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  1. Article: Soft microswimmers: Material capabilities and biomedical applications

    Yan, Guanghui / Solovev, Alexander A. / Huang, Gaoshan / Cui, Jizhai / Mei, Yongfeng

    Current opinion in colloid & interface science. 2022,

    2022  

    Abstract: In the last decades, microrobotics has attracted much attention of researchers due to the unique characteristics of shapes, propulsion mechanisms, and potential applications in the biomedical field. Recently, the research of microrobots has shifted to ... ...

    Abstract In the last decades, microrobotics has attracted much attention of researchers due to the unique characteristics of shapes, propulsion mechanisms, and potential applications in the biomedical field. Recently, the research of microrobots has shifted to soft microrobots owing to their softness, elasticity and reconfigurability benefiting to interact with the complex channels in the human body compared to their rigid counterparts. There is significant progress on soft microswimmers and that encourages us to review this field timely to promote the development. In this review, we mainly highlight the progress of the soft microswimmers in recent years. The materials with softness, deformability and shape-morphing characteristics are surveyed as well as biocompatibility, followed by standard fabrication methods. Additionally, the locomotion based on self-propelled and external-field-driven mechanisms has been compared and discussed. Finally, the biomedical applications in imaging, targeted drug delivery and therapy, and microsurgery are highlighted followed by addressing the perspectives.
    Keywords biocompatibility ; drugs ; hardness ; humans ; locomotion ; therapeutics
    Language English
    Publishing place Elsevier Ltd
    Document type Article
    Note Pre-press version
    ZDB-ID 2019683-0
    ISSN 1359-0294
    ISSN 1359-0294
    DOI 10.1016/j.cocis.2022.101609
    Database NAL-Catalogue (AGRICOLA)

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  2. Article ; Online: Shape Memory Alloy Helical Microrobots with Transformable Capability towards Vascular Occlusion Treatment.

    Zhang, Hehua / Xu, Borui / Ouyang, Yi / Wang, Yunqi / Zhu, Hong / Huang, Gaoshan / Cui, Jizhai / Mei, Yongfeng

    Research (Washington, D.C.)

    2022  Volume 2022, Page(s) 9842752

    Abstract: Practical implementation of minimally invasive biomedical applications has been a long-sought goal for microrobots. In this field, most previous studies only demonstrate microrobots with locomotion ability or performing a single task, unable to be ... ...

    Abstract Practical implementation of minimally invasive biomedical applications has been a long-sought goal for microrobots. In this field, most previous studies only demonstrate microrobots with locomotion ability or performing a single task, unable to be functionalized effectively. Here, we propose a biocompatible shape memory alloy helical microrobot with regulative structure transformation, making it possible to adjust its motion behavior and mechanical properties precisely. Especially, towards vascular occlusion problem, these microrobots reveal a fundamental solution strategy in the mechanical capability using shape memory effect. Such shape-transformable microrobots can not only manipulate thrust and torque by structure to enhance the unclogging efficiency as a microdriller but also utilize the high work energy to apply the expandable helical tail as a self-propulsive stent. The strategy takes advantage of untethered manipulation to operate microsurgery without unnecessary damage. This study opens a route to functionalize microrobots via accurate tuning in structures, motions, and mechanical properties.
    Language English
    Publishing date 2022-07-06
    Publishing country United States
    Document type Journal Article
    ISSN 2639-5274
    ISSN (online) 2639-5274
    DOI 10.34133/2022/9842752
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Multilevel design and construction in nanomembrane rolling for three-dimensional angle-sensitive photodetection.

    Zhang, Ziyu / Wu, Binmin / Wang, Yang / Cai, Tianjun / Ma, Mingze / You, Chunyu / Liu, Chang / Jiang, Guobang / Hu, Yuhang / Li, Xing / Chen, Xiang-Zhong / Song, Enming / Cui, Jizhai / Huang, Gaoshan / Kiravittaya, Suwit / Mei, Yongfeng

    Nature communications

    2024  Volume 15, Issue 1, Page(s) 3066

    Abstract: Releasing pre-strained two-dimensional nanomembranes to assemble on-chip three-dimensional devices is crucial for upcoming advanced electronic and optoelectronic applications. However, the release process is affected by many unclear factors, hindering ... ...

    Abstract Releasing pre-strained two-dimensional nanomembranes to assemble on-chip three-dimensional devices is crucial for upcoming advanced electronic and optoelectronic applications. However, the release process is affected by many unclear factors, hindering the transition from laboratory to industrial applications. Here, we propose a quasistatic multilevel finite element modeling to assemble three-dimensional structures from two-dimensional nanomembranes and offer verification results by various bilayer nanomembranes. Take Si/Cr nanomembrane as an example, we confirm that the three-dimensional structural formation is governed by both the minimum energy state and the geometric constraints imposed by the edges of the sacrificial layer. Large-scale, high-yield fabrication of three-dimensional structures is achieved, and two distinct three-dimensional structures are assembled from the same precursor. Six types of three-dimensional Si/Cr photodetectors are then prepared to resolve the incident angle of light with a deep neural network model, opening up possibilities for the design and manufacturing methods of More-than-Moore-era devices.
    Language English
    Publishing date 2024-04-09
    Publishing country England
    Document type Journal Article
    ZDB-ID 2553671-0
    ISSN 2041-1723 ; 2041-1723
    ISSN (online) 2041-1723
    ISSN 2041-1723
    DOI 10.1038/s41467-024-47405-2
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Bridging the gap: harnessing liquid nanomachine know-how for tackling harmful airborne particulates.

    Kuzin, Aleksei / Chen, Guoxiang / Zhu, Fenyang / Gorin, Dmitry / Mohan, Brij / Choudhury, Udit / Cui, Jizhai / Modi, Krunal / Huang, Gaoshan / Mei, Yongfeng / Solovev, Alexander A

    Nanoscale

    2023  Volume 15, Issue 44, Page(s) 17727–17738

    Abstract: The emergence of "nanomotors", "nanomachines", and "nanorobotics" has transformed dynamic nanoparticle research, driving a transition from passive to active and intelligent nanoscale systems. This review examines two critical fields: the investigation of ...

    Abstract The emergence of "nanomotors", "nanomachines", and "nanorobotics" has transformed dynamic nanoparticle research, driving a transition from passive to active and intelligent nanoscale systems. This review examines two critical fields: the investigation of airborne particles, significant contributors to air pollution, and the rapidly emerging domain of catalytic and field-controlled nano- and micromotors. We examine the basic concepts of nano- and micromachines in motion and envision their possible use in a gaseous medium to trap and neutralize hazardous particulates. While past studies described the application of nanotechnology and nanomotors in various scenarios, airborne nano/micromachine motion and their control have yet to be thoroughly explored. This review intends to promote multidisciplinary research on nanomachines' propulsion and task-oriented applications, highlighting their relevance in obtaining a cleaner atmospheric environment, a critical component to consider for human health.
    MeSH term(s) Humans ; Nanotechnology ; Motion ; Nanoparticles ; Catalysis
    Language English
    Publishing date 2023-11-16
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 2515664-0
    ISSN 2040-3372 ; 2040-3364
    ISSN (online) 2040-3372
    ISSN 2040-3364
    DOI 10.1039/d3nr03808d
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: One-step rolling fabrication of VO

    Wu, Binmin / Zhang, Ziyu / Chen, Bingxin / Zheng, Zhi / You, Chunyu / Liu, Chang / Li, Xing / Wang, Jinlong / Wang, Yunqi / Song, Enming / Cui, Jizhai / An, Zhenghua / Huang, Gaoshan / Mei, Yongfeng

    Science advances

    2023  Volume 9, Issue 42, Page(s) eadi7805

    Abstract: Uncooled infrared detection based on vanadium dioxide ( ... ...

    Abstract Uncooled infrared detection based on vanadium dioxide (VO
    Language English
    Publishing date 2023-10-18
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2810933-8
    ISSN 2375-2548 ; 2375-2548
    ISSN (online) 2375-2548
    ISSN 2375-2548
    DOI 10.1126/sciadv.adi7805
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Self-Rolled-Up Ultrathin Single-Crystalline Silicon Nanomembranes for On-Chip Tubular Polarization Photodetectors.

    Wu, Binmin / Zhang, Ziyu / Zheng, Zhi / Cai, Tianjun / You, Chunyu / Liu, Chang / Li, Xing / Wang, Yang / Wang, Jinlong / Li, Hongbin / Song, Enming / Cui, Jizhai / Huang, Gaoshan / Mei, Yongfeng

    Advanced materials (Deerfield Beach, Fla.)

    2023  Volume 35, Issue 52, Page(s) e2306715

    Abstract: Freestanding single-crystalline nanomembranes and their assembly have broad application potential in photodetectors for integrated chips. However, the release and self-assembly process of single-crystalline semiconductor nanomembranes still remains a ... ...

    Abstract Freestanding single-crystalline nanomembranes and their assembly have broad application potential in photodetectors for integrated chips. However, the release and self-assembly process of single-crystalline semiconductor nanomembranes still remains a great challenge in on-chip processing and functional integration, and photodetectors based on nanomembrane always suffer from limited absorption of nanoscale thickness. Here, a non-destructive releasing and rolling process is employed to prepare tubular photodetectors based on freestanding single-crystalline Si nanomembranes. Spontaneous release and self-assembly are achieved by residual strain introduced by lattice mismatch at the epitaxial interface of Si and Ge, and the intrinsic stress and strain distributions in self-rolled-up Si nanomembranes are analyzed experimentally and computationally. The advantages of light trapping and wide-angle optical coupling are realized by tubular geometry. This Si microtube device achieves reliable Ohmic contact and exhibits a photoresponsivity of over 330 mA W
    Language English
    Publishing date 2023-11-20
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 1474949-X
    ISSN 1521-4095 ; 0935-9648
    ISSN (online) 1521-4095
    ISSN 0935-9648
    DOI 10.1002/adma.202306715
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: Flying Squirrel-Inspired Motion Control of a Light-Deformed Pt-PAzoMA Micromotor through Drag Force Manipulation

    Lin, Xinyi / Xu, Borui / Zhao, Zhe / Yang, Xiaoyan / Xing, Yi / You, Chunyu / Kong, Ye / Cui, Jizhai / Zhu, Liangliang / Lin, Shaoliang / Mei, Yongfeng

    ACS applied materials & interfaces. 2021 June 18, v. 13, no. 25

    2021  

    Abstract: Micromotors require stable and precise motion control for complex tasks such as microsurgery, drug delivery in vivo, or environmental monitoring ex vivo. However, a continuous control signal is needed for micromotors to achieve motion control during ... ...

    Abstract Micromotors require stable and precise motion control for complex tasks such as microsurgery, drug delivery in vivo, or environmental monitoring ex vivo. However, a continuous control signal is needed for micromotors to achieve motion control during their whole journey, which hinders their application in areas where external control stimuli are limited or unavailable. Fortunately, nature suggests an excellent solution that flying squirrel exhibits motion tuning capability by deforming itself when jumping off a tall tree. Inspired by this, we propose a Pt-PAzoMA Janus micromotor that precisely changes its shape (from a spherical shape to an elliptical shape) under a brief light signal (450 nm) and maintains this deformation until next signal reception. The deformed elliptical micromotor performs relatively low-speed motion compared to the spherical one, which is further confirmed by massive simulation results. In addition, by investigating motion behavior experimentally and theoretically, it is proved that the motion modulation is caused by the drag force changing brought from the deformation. This method represents a different route to regulate the motion of micromotors without a continuous signal, which is useful in application scenarios where the environmental control signal is inaccessible/limited or long-time operation with minimum energy input is required to maintain motion manipulation. With further function modification, this kind of shape-changing micromotor has potential in optimizing drug diffusion efficiency by speed altering and long-term monitoring at the diseased area by confining the active range of the micromotor in the targeted area through deformation.
    Keywords deformation ; drugs ; energy ; nanoparticles ; trees
    Language English
    Dates of publication 2021-0618
    Size p. 30106-30117.
    Publishing place American Chemical Society
    Document type Article
    ISSN 1944-8252
    DOI 10.1021/acsami.1c07569
    Database NAL-Catalogue (AGRICOLA)

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  8. Article ; Online: Publisher Correction: Nanomagnetic encoding of shape-morphing micromachines.

    Cui, Jizhai / Huang, Tian-Yun / Luo, Zhaochu / Testa, Paolo / Gu, Hongri / Chen, Xiang-Zhong / Nelson, Bradley J / Heyderman, Laura J

    Nature

    2020  Volume 578, Issue 7793, Page(s) E10

    Abstract: An Amendment to this paper has been published and can be accessed via a link at the top of the paper. ...

    Abstract An Amendment to this paper has been published and can be accessed via a link at the top of the paper.
    Language English
    Publishing date 2020-01-14
    Publishing country England
    Document type Journal Article ; Published Erratum
    ZDB-ID 120714-3
    ISSN 1476-4687 ; 0028-0836
    ISSN (online) 1476-4687
    ISSN 0028-0836
    DOI 10.1038/s41586-019-1888-6
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 26: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)
    Zs.MG 9: Show issues
    Zs.MO 244: Show issues

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  9. Article: Integration of a Metal–Organic Framework Film with a Tubular Whispering-Gallery-Mode Microcavity for Effective CO₂ Sensing

    Kong, Ye / Zhao, Zhe / Wang, Yunqi / Yang, Shuo / Huang, Gaoshan / Wang, Yang / Liu, Chang / You, Chunyu / Tan, Ji / Wang, Chao / Xu, Borui / Cui, Jizhai / Liu, Xuanyong / Mei, Yongfeng

    ACS applied materials & interfaces. 2021 Nov. 23, v. 13, no. 48

    2021  

    Abstract: Carbon dioxide (CO₂) sensing using an optical technique is of great importance in the environment and industrial emission monitoring. However, limited by the poor specific adsorption of gas molecules as well as insufficient coupling efficiency, there is ... ...

    Abstract Carbon dioxide (CO₂) sensing using an optical technique is of great importance in the environment and industrial emission monitoring. However, limited by the poor specific adsorption of gas molecules as well as insufficient coupling efficiency, there is still a long way to go toward realizing a highly sensitive optical CO₂ gas sensor. Herein, by combining the advantages of a whispering-gallery-mode microcavity and a metal–organic framework (MOF) film, a porous functional microcavity (PF-MC) was fabricated with the assistance of the atomic layer deposition technique and was applied to CO₂ sensing. In this functional composite, the rolled-up microcavity provides the ability to tune the propagation of light waves and the electromagnetic coupling with the surroundings via an evanescent field, while the nanoporous MOF film contributes to the specific adsorption of CO₂. The composite demonstrates a high sensitivity of 188 nm RIU–¹ (7.4 pm/% with respect to the CO₂ concentration) and a low detection limit of ∼5.85 × 10–⁵ RIU. Furthermore, the PF-MC exhibits great selectivity to CO₂ and outstanding reproducibility, which is promising for the next-generation optical gas sensing devices.
    Keywords adsorption ; carbon dioxide ; coordination polymers ; detection limit ; nanopores
    Language English
    Dates of publication 2021-1123
    Size p. 58104-58113.
    Publishing place American Chemical Society
    Document type Article
    ISSN 1944-8252
    DOI 10.1021/acsami.1c16322
    Database NAL-Catalogue (AGRICOLA)

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  10. Article ; Online: Nanomagnetic encoding of shape-morphing micromachines.

    Cui, Jizhai / Huang, Tian-Yun / Luo, Zhaochu / Testa, Paolo / Gu, Hongri / Chen, Xiang-Zhong / Nelson, Bradley J / Heyderman, Laura J

    Nature

    2019  Volume 575, Issue 7781, Page(s) 164–168

    Abstract: Shape-morphing systems, which can perform complex tasks through morphological transformations, are of great interest for future applications in minimally invasive ... ...

    Abstract Shape-morphing systems, which can perform complex tasks through morphological transformations, are of great interest for future applications in minimally invasive medicine
    Language English
    Publishing date 2019-11-06
    Publishing country England
    Document type Journal Article
    ZDB-ID 120714-3
    ISSN 1476-4687 ; 0028-0836
    ISSN (online) 1476-4687
    ISSN 0028-0836
    DOI 10.1038/s41586-019-1713-2
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 26: Show issues Location:
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    Zs.MO 244: Show issues

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