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  1. Article ; Online: Coinfección por COVID-19 y gripe A: una cuestión de principios.

    Lozano-Parras, M Angeles / Amann-Arévalo, Marta / Ciller-Martínez, Marta / Culebras-López, Esther

    Enfermedades infecciosas y microbiologia clinica

    2020  Volume 39, Issue 4, Page(s) 214–215

    Title translation COVID-19 and influenza A coinfection: a matter of principle.
    Language Spanish
    Publishing date 2020-07-16
    Publishing country Spain
    Document type Case Reports
    ZDB-ID 1070941-1
    ISSN 1578-1852 ; 0213-005X
    ISSN (online) 1578-1852
    ISSN 0213-005X
    DOI 10.1016/j.eimc.2020.06.017
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

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  2. Article ; Online: COVID-19 and influenza A coinfection: a matter of principle.

    Lozano-Parras, M Angeles / Amann-Arévalo, Marta / Ciller-Martínez, Marta / Culebras-López, Esther

    Enfermedades infecciosas y microbiologia clinica (English ed.)

    2020  Volume 39, Issue 4, Page(s) 214–215

    Title translation Coinfección por COVID-19 y gripe A: una cuestión de principios.
    MeSH term(s) Adrenal Cortex Hormones/adverse effects ; Adrenal Cortex Hormones/pharmacology ; Adrenal Cortex Hormones/therapeutic use ; Anti-Inflammatory Agents/adverse effects ; Anti-Inflammatory Agents/pharmacology ; Anti-Inflammatory Agents/therapeutic use ; COVID-19/complications ; COVID-19/diagnostic imaging ; COVID-19/virology ; COVID-19 Nucleic Acid Testing ; Coinfection/virology ; Contraindications, Drug ; Female ; Humans ; Immunosuppressive Agents/adverse effects ; Immunosuppressive Agents/pharmacology ; Immunosuppressive Agents/therapeutic use ; Influenza A virus/isolation & purification ; Influenza, Human/complications ; Influenza, Human/drug therapy ; Influenza, Human/virology ; Middle Aged ; Nasopharynx/virology ; Pneumonia, Viral/diagnostic imaging ; Pneumonia, Viral/drug therapy ; Pneumonia, Viral/etiology ; Remission Induction ; SARS-CoV-2/drug effects ; SARS-CoV-2/isolation & purification ; COVID-19 Drug Treatment
    Chemical Substances Adrenal Cortex Hormones ; Anti-Inflammatory Agents ; Immunosuppressive Agents
    Keywords covid19
    Language Spanish
    Publishing date 2020-07-16
    Publishing country Spain
    Document type Case Reports
    ISSN 2529-993X
    ISSN (online) 2529-993X
    DOI 10.1016/j.eimc.2020.06.017
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Coinfección por COVID-19 y gripe A: una cuestión de principios./ Coinfección por COVID-19 y gripe A: una cuestión de principios./ COVID-19 and influenza A coinfection: a matter of principle

    Lozano-Parras, M Angeles / Amann-Arévalo, Marta / Ciller-Martínez, Marta / Culebras-López, Esther

    Enferm. infecc. microbiol. clin. (Ed. impr.)

    Keywords covid19
    Publisher WHO
    Document type Article
    Note WHO #Covidence: #650927
    Database COVID19

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  4. Article ; Online: Coinfección por COVID-19 y gripe A

    Lozano-Parras, M. Angeles / Amann-Arévalo, Marta / Ciller-Martínez, Marta / Culebras-López, Esther

    Enfermedades Infecciosas y Microbiología Clínica ; ISSN 0213-005X

    una cuestión de principios

    2020  

    Keywords Microbiology (medical) ; covid19
    Language Spanish
    Publisher Elsevier BV
    Publishing country us
    Document type Article ; Online
    DOI 10.1016/j.eimc.2020.06.017
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  5. Article: Specific Cellular and Humoral Response after the Third Dose of Anti-SARS-CoV-2 RNA Vaccine in Patients with Immune-Mediated Rheumatic Diseases on Immunosuppressive Therapy.

    Mohamed Mohamed, Kauzar / Álvarez-Hernández, María Paula / Jiménez García, Carlos / Guevara-Hoyer, Kissy / Freites, Dalifer / Martínez Prada, Cristina / Pérez-Sancristóbal, Inés / Fernández Gutiérrez, Benjamín / Mato Chaín, Gloria / Rodero, Maria / Rodríguez de la Peña, Antonia / Mulero, Teresa / Bravo, Cecilia / Toledano, Esther / Culebras López, Esther / Mediero Valeros, Beatriz / Pérez Segura, Pedro / Sánchez-Ramón, Silvia / Candelas Rodríguez, Gloria

    Biomedicines

    2023  Volume 11, Issue 9

    Abstract: Objective: Data on cellular and humoral immunogenicity after the third dose of anti-SARS-CoV-2 vaccines in patients with immune-mediated rheumatic diseases (IMRDs) are scarce. Herein, we evaluated the adaptive immune response in IMRD patients treated ... ...

    Abstract Objective: Data on cellular and humoral immunogenicity after the third dose of anti-SARS-CoV-2 vaccines in patients with immune-mediated rheumatic diseases (IMRDs) are scarce. Herein, we evaluated the adaptive immune response in IMRD patients treated with different immunosuppressive therapies (conventional synthetic disease-modifying antirheumatic drugs [csDMARDs], biological disease-modifying antirheumatic drugs [bDMARDs], and targeted synthetic disease-modifying antirheumatic drugs [tsDMARDs]) after the booster of the anti-SARS-CoV-2 vaccine to determine whether any drug reduced the vaccine's response.
    Methods: A single-center prospective study was conducted, including patients presenting with IMRD and healthy controls (HC). Specific anti-SARS-CoV-2 interferon-gamma (IFN-γ) production was evaluated between 8-12 weeks after the third dose of the SARS-CoV-2 vaccine. In addition, anti-Spike IgG antibody titers were also measured.
    Results: Samples were obtained from 79 IMRD patients (51 women, 28 men; mean age 57 ± 11.3 years old): 43 rheumatoid arthritis, 10 psoriatic arthritis, 14 ankylosing spondylitis, 10 undifferentiated spondyloarthritis, and 2 inflammatory bowel disease-associated spondyloarthritis (IBD-SpA). In total, 31 HC (mean age 50.9 ± 13.1 years old, 67.7% women) were included in the study. Post-vaccine results displayed positive T-cell immune responses in 68 out of 79 (86.1%) IMRD patients (82.3% of those without prior COVID-19). All HC and IMRDs patients had an antibody response against the SARS-CoV-2 receptor-binding domain; however, the HC response was significantly higher (median of 18,048 AU/mL) than in IMRDs patients (median of 6590.3 AU/mL,
    Conclusion: Our preliminary data show that the majority of our IMRD patients develop cellular and humoral responses after the SARS-CoV-2 booster vaccination, emphasizing the relevance of vaccination in this group. However, the magnitude of specific responses was dependent on the immunosuppressive therapy administered. Specific vaccination protocols and personalized decisions about boosters are essential for these patients.
    Language English
    Publishing date 2023-08-29
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2720867-9
    ISSN 2227-9059
    ISSN 2227-9059
    DOI 10.3390/biomedicines11092418
    Database MEDical Literature Analysis and Retrieval System OnLINE

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