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Article ; Online: PD-1 Blockade Modulates Functional Activities of Exhausted-Like T Cell in Patients With Cutaneous Leishmaniasis.

Garcia de Moura, Renan / Covre, Luciana Polaco / Fantecelle, Carlos Henrique / Gajardo, Vitor Alejandro Torres / Cunha, Carla Baroni / Stringari, Lorenzzo Lyrio / Belew, Ashton Trey / Daniel, Camila Batista / Zeidler, Sandra Ventorin Von / Tadokoro, Carlos Eduardo / de Matos Guedes, Herbert Leonel / Zanotti, Raphael Lubiana / Mosser, David / Falqueto, Aloisio / Akbar, Arne N / Gomes, Daniel Claudio Oliveira

Frontiers in immunology

2021  Volume 12, Page(s) 632667

Abstract: Patients infected ... ...

Abstract Patients infected by
MeSH term(s) Adult ; Cell Proliferation/drug effects ; Female ; Humans ; Immune Checkpoint Inhibitors/pharmacology ; Immune Checkpoint Proteins/metabolism ; Immunosenescence ; Inflammation ; Interferon-gamma/immunology ; Leishmania braziliensis/pathogenicity ; Leishmaniasis, Cutaneous/immunology ; Male ; Middle Aged ; Programmed Cell Death 1 Receptor/antagonists & inhibitors ; Programmed Cell Death 1 Receptor/metabolism ; Skin/immunology ; T-Lymphocyte Subsets/drug effects ; T-Lymphocyte Subsets/immunology ; T-Lymphocyte Subsets/metabolism ; T-Lymphocytes/drug effects ; T-Lymphocytes/immunology ; T-Lymphocytes/metabolism
Chemical Substances IFNG protein, human ; Immune Checkpoint Inhibitors ; Immune Checkpoint Proteins ; PDCD1 protein, human ; Programmed Cell Death 1 Receptor ; Interferon-gamma (82115-62-6)
Language English
Publishing date 2021-03-09
Publishing country Switzerland
Document type Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID 2606827-8
ISSN 1664-3224 ; 1664-3224
ISSN (online) 1664-3224
ISSN 1664-3224
DOI 10.3389/fimmu.2021.632667
Database MEDical Literature Analysis and Retrieval System OnLINE

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