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  1. Article ; Online: Trends in Laboratory-Confirmed SARS-CoV-2 Reinfections and Associated Hospitalizations and Deaths Among Adults Aged ≥18 Years - 18 U.S. Jurisdictions, September 2021-December 2022.

    Ma, Kevin C / Dorabawila, Vajeera / León, Tomás M / Henry, Hannah / Johnson, Amelia G / Rosenberg, Eli / Mansfield, Joshua A / Midgley, Claire M / Plumb, Ian D / Aiken, Julia / Khanani, Quratul Ain / Auche, Steven / Bayoumi, Nagla S / Bennett, Sarah A / Bernu, Carmen / Chang, Carolyn / Como-Sabetti, Kathryn J / Cueto, Kevin / Cunningham, Spencer /
    Eddy, Meredith / Falender, Rebecca A / Fleischauer, Aaron / Frank, Darren M / Harrington, Pauline / Hoskins, Mikhail / Howsare, Adam / Ingaiza, Lucy M / Islam, Aras S / Jensen, Shelli A / Jones, Jefferson M / Kambach, Grace / Kanishka, Fnu / Levin, Yuriy / Masarik, John F / Meyer, Stephanie D / Milroy, Lauren / Morris, Keeley J / Olmstead, John / Olsen, Nina S / Omoike, Enaholo / Patel, Komal / Pettinger, Amanda / Pike, Melissa A / Reed, Isaiah G / Slocum, Elizabeth / Sutton, Melissa / Tilakaratne, Buddhi P / Vest, Hailey / Vostok, Johanna / Wang, Jennifer S / Watson-Lewis, Lydia / Wienkes, Haley N / Hagen, Melissa Briggs / Silk, Benjamin J / Scobie, Heather M

    MMWR. Morbidity and mortality weekly report

    2023  Volume 72, Issue 25, Page(s) 683–689

    Abstract: Although reinfections with SARS-CoV-2 have occurred in the United States with increasing frequency, U.S. epidemiologic trends in reinfections and associated severe outcomes have not been characterized. Weekly counts of SARS-CoV-2 reinfections, total ... ...

    Abstract Although reinfections with SARS-CoV-2 have occurred in the United States with increasing frequency, U.S. epidemiologic trends in reinfections and associated severe outcomes have not been characterized. Weekly counts of SARS-CoV-2 reinfections, total infections, and associated hospitalizations and deaths reported by 18 U.S. jurisdictions during September 5, 2021-December 31, 2022, were analyzed overall, by age group, and by five periods of SARS-CoV-2 variant predominance (Delta and Omicron [BA.1, BA.2, BA.4/BA.5, and BQ.1/BQ.1.1]). Among reported reinfections, weekly trends in the median intervals between infections and frequencies of predominant variants during previous infections were calculated. As a percentage of all infections, reinfections increased substantially from the Delta (2.7%) to the Omicron BQ.1/BQ.1.1 (28.8%) periods; during the same periods, increases in the percentages of reinfections among COVID-19-associated hospitalizations (from 1.9% [Delta] to 17.0% [Omicron BQ.1/BQ.1.1]) and deaths (from 1.2% [Delta] to 12.3% [Omicron BQ.1/BQ.1.1]) were also substantial. Percentages of all COVID-19 cases, hospitalizations, and deaths that were reinfections were consistently higher across variant periods among adults aged 18-49 years compared with those among adults aged ≥50 years. The median interval between infections ranged from 269 to 411 days by week, with a steep decline at the start of the BA.4/BA.5 period, when >50% of reinfections occurred among persons previously infected during the Alpha variant period or later. To prevent severe COVID-19 outcomes, including those following reinfection, CDC recommends staying up to date with COVID-19 vaccination and receiving timely antiviral treatments, when eligible.
    MeSH term(s) Adolescent ; Adult ; Humans ; COVID-19/diagnosis ; COVID-19/epidemiology ; COVID-19 Vaccines ; Hospitalization/trends ; Reinfection/epidemiology ; SARS-CoV-2 ; Hospital Mortality
    Chemical Substances COVID-19 Vaccines
    Language English
    Publishing date 2023-06-23
    Publishing country United States
    Document type Journal Article
    ZDB-ID 412775-4
    ISSN 1545-861X ; 0149-2195
    ISSN (online) 1545-861X
    ISSN 0149-2195
    DOI 10.15585/mmwr.mm7225a3
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: COVID-19 Incidence and Mortality Among Unvaccinated and Vaccinated Persons Aged ≥12 Years by Receipt of Bivalent Booster Doses and Time Since Vaccination - 24 U.S. Jurisdictions, October 3, 2021-December 24, 2022.

    Johnson, Amelia G / Linde, Lauren / Ali, Akilah R / DeSantis, Allison / Shi, Minchan / Adam, Carolyn / Armstrong, Brandy / Armstrong, Brett / Asbell, Madison / Auche, Steven / Bayoumi, Nagla S / Bingay, Boudu / Chasse, Melisse / Christofferson, Scott / Cima, Michael / Cueto, Kevin / Cunningham, Spencer / Delgadillo, Janelle / Dorabawila, Vajeera /
    Drenzek, Cherie / Dupervil, Brandi / Durant, Tonji / Fleischauer, Aaron / Hamilton, Ross / Harrington, Pauline / Hicks, Liam / Hodis, Jeffrey D / Hoefer, Dina / Horrocks, Sam / Hoskins, Mikhail / Husain, Sofia / Ingram, L Amanda / Jara, Amanda / Jones, Amanda / Kanishka, F N U / Kaur, Ramandeep / Khan, Saadiah I / Kirkendall, Samantha / Lauro, Priscilla / Lyons, Shelby / Mansfield, Joshua / Markelz, Amanda / Masarik, John / McCormick, Donald / Mendoza, Erica / Morris, Keeley J / Omoike, Enaholo / Patel, Komal / Pike, Melissa A / Pilishvili, Tamara / Praetorius, Kevin / Reed, Isaiah G / Severson, Rachel L / Sigalo, Nekabari / Stanislawski, Emma / Stich, Sarah / Tilakaratne, Buddhi P / Turner, Kathryn A / Wiedeman, Caleb / Zaldivar, Allison / Silk, Benjamin J / Scobie, Heather M

    MMWR. Morbidity and mortality weekly report

    2023  Volume 72, Issue 6, Page(s) 145–152

    Abstract: On September 1, 2022, CDC recommended an updated (bivalent) COVID-19 vaccine booster to help restore waning protection conferred by previous vaccination and broaden protection against emerging variants for persons aged ≥12 years (subsequently extended to ...

    Abstract On September 1, 2022, CDC recommended an updated (bivalent) COVID-19 vaccine booster to help restore waning protection conferred by previous vaccination and broaden protection against emerging variants for persons aged ≥12 years (subsequently extended to persons aged ≥6 months).* To assess the impact of original (monovalent) COVID-19 vaccines and bivalent boosters, case and mortality rate ratios (RRs) were estimated comparing unvaccinated and vaccinated persons aged ≥12 years by overall receipt of and by time since booster vaccination (monovalent or bivalent) during Delta variant and Omicron sublineage (BA.1, BA.2, early BA.4/BA.5, and late BA.4/BA.5) predominance.
    MeSH term(s) Humans ; Aged ; COVID-19 Vaccines ; COVID-19/epidemiology ; COVID-19/prevention & control ; Incidence ; SARS-CoV-2 ; Vaccination
    Chemical Substances COVID-19 Vaccines
    Language English
    Publishing date 2023-02-10
    Publishing country United States
    Document type Journal Article
    ZDB-ID 412775-4
    ISSN 1545-861X ; 0149-2195
    ISSN (online) 1545-861X
    ISSN 0149-2195
    DOI 10.15585/mmwr.mm7206a3
    Database MEDical Literature Analysis and Retrieval System OnLINE

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