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  1. Article ; Online: Bilateral acute depigmentation of the iris (BADI) and bilateral acute iris transillumination (BAIT): A case series from a center in Brazil.

    Costa, Flavia Veiga / Silva, Amanda Gomes E / Pedroso, Leticia Alcântara / Biancardi, Ana Luiza / Curi, André Luiz Land

    Arquivos brasileiros de oftalmologia

    2024  Volume 87, Issue 4, Page(s) e2023

    Abstract: Bilateral acute depigmentation of the iris and bilateral acute iris transillumination (BAIT) are similar clinical entities. The former causes acute-onset depigmentation of the iris stroma without transillumination, whereas the latter causes ... ...

    Abstract Bilateral acute depigmentation of the iris and bilateral acute iris transillumination (BAIT) are similar clinical entities. The former causes acute-onset depigmentation of the iris stroma without transillumination, whereas the latter causes depigmentation of the iris pigment epithelium with transillumination. The etiopathogenesis of these conditions is not yet fully understood, but the proposed causes include the use of systemic antibiotics (especially moxifloxacin) and viral triggers. We present a case series of five female patients with a mean age of 41 (32-45) years, all of whom suffered acute onset of bilateral pain and redness of the eyes after moxifloxacin use (oral or topical). It is important for ophthalmologists to be aware of the two forms of iris depigmentation since this case series suggests that SARS-CoV-2 or its empirical treatment with moxifloxacin may trigger iris depigmentation. If this is the case, clinicians will likely see increased incidences of bilateral acute depigmentation of the iris and bilateral acute iris transillumination during and after the COVID-19 pandemic.
    MeSH term(s) Humans ; Female ; Adult ; Iris Diseases/chemically induced ; Middle Aged ; COVID-19/complications ; Brazil ; Acute Disease ; Moxifloxacin/adverse effects ; Moxifloxacin/therapeutic use ; Transillumination ; SARS-CoV-2 ; Pigmentation Disorders/chemically induced ; Iris/pathology ; Anti-Bacterial Agents/adverse effects ; Pigment Epithelium of Eye/pathology ; Pigment Epithelium of Eye/drug effects
    Chemical Substances Moxifloxacin (U188XYD42P) ; Anti-Bacterial Agents
    Language English
    Publishing date 2024-04-19
    Publishing country Brazil
    Document type Case Reports
    ZDB-ID 603915-7
    ISSN 1678-2925 ; 0004-2749
    ISSN (online) 1678-2925
    ISSN 0004-2749
    DOI 10.5935/0004-2749.2023-0219
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Re: "Orbital Cellulitis in Chagas Disease: An Unusual Presentation".

    Hasslocher Moreno, Alejandro Marcel / Curi, Andre Luiz Land

    Ophthalmic plastic and reconstructive surgery

    2021  Volume 37, Issue 5, Page(s) 500

    MeSH term(s) Chagas Disease/complications ; Chagas Disease/diagnosis ; Humans ; Orbital Cellulitis/diagnosis ; Orbital Cellulitis/etiology ; Orbital Diseases/diagnosis ; Orbital Diseases/etiology
    Language English
    Publishing date 2021-09-15
    Publishing country United States
    Document type Journal Article ; Comment
    ZDB-ID 632830-1
    ISSN 1537-2677 ; 0740-9303
    ISSN (online) 1537-2677
    ISSN 0740-9303
    DOI 10.1097/IOP.0000000000002040
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  3. Article ; Online: Indocyanine green angiographic findings in a patient with AIDS and disseminated sporotrichosis.

    Biancardi, Ana Luiza / Moraes, Raíssa Lima de / Curi, André Luiz Land

    Arquivos brasileiros de oftalmologia

    2022  Volume 85, Issue 3, Page(s) 320–321

    MeSH term(s) Acquired Immunodeficiency Syndrome/drug therapy ; Angiography ; Antifungal Agents/therapeutic use ; Humans ; Indocyanine Green ; Sporotrichosis/diagnostic imaging ; Sporotrichosis/drug therapy
    Chemical Substances Antifungal Agents ; Indocyanine Green (IX6J1063HV)
    Language English
    Publishing date 2022-06-22
    Publishing country Brazil
    Document type Letter
    ZDB-ID 603915-7
    ISSN 1678-2925 ; 0004-2749
    ISSN (online) 1678-2925
    ISSN 0004-2749
    DOI 10.5935/0004-2749.202200102
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  4. Article ; Online: Pediatric Posterior Infectious Uveitis.

    Curi, André Luiz Land / de-la-Torre, Alejandra / Schlaen, Ariel / Mahendradas, Papdmamalini / Biswas, Jyortimay

    Ocular immunology and inflammation

    2023  Volume 31, Issue 10, Page(s) 1944–1954

    Abstract: Purpose: To describe the most important cause of infectious posterior uveitis in pediatric patients.: Methods: Review of the literature.: Results: The most important causes of infectious uveitis in pediatric patients are: cat-scratch disease, ... ...

    Abstract Purpose: To describe the most important cause of infectious posterior uveitis in pediatric patients.
    Methods: Review of the literature.
    Results: The most important causes of infectious uveitis in pediatric patients are: cat-scratch disease, toxocariasis, tuberculosis, viral diseases and toxoplasmosis. Ocular manifestations include retinitis, neuroretinitis, choroidal granulomas, peripheral granulomas and posterior pole granulomas.
    Conclusion: Infectious posterior uveitis is a challenging subject and should be considered in the differential diagnosis of any posterior uveitis in children. Infectious uveitis must be excluded before initiating immunosuppressive therapy.
    MeSH term(s) Animals ; Humans ; Child ; Uveitis, Posterior/diagnosis ; Uveitis, Posterior/drug therapy ; Uveitis/diagnosis ; Uveitis/drug therapy ; Retinitis/diagnosis ; Retinitis/drug therapy ; Eye Infections/diagnosis ; Eye Infections/drug therapy ; Eye Infections, Bacterial/diagnosis ; Choroid ; Granuloma
    Language English
    Publishing date 2023-12-14
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 1193873-0
    ISSN 1744-5078 ; 0927-3948
    ISSN (online) 1744-5078
    ISSN 0927-3948
    DOI 10.1080/09273948.2023.2284990
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  5. Article ; Online: Monkeypox Infection Causing Conjunctival Vesicles and Anterior Uveitis.

    Carvalho, Erika Moreira / Medeiros, Manuela / Veloso, Valdilea Gonçalves / Biancardi, Ana Luiza / Curi, André Luiz Land

    Ocular immunology and inflammation

    2023  Volume 32, Issue 3, Page(s) 266–267

    Abstract: Human monkeypox is a zoonosis caused by ... ...

    Abstract Human monkeypox is a zoonosis caused by an
    MeSH term(s) Animals ; Humans ; Mpox (monkeypox) ; Monkeypox virus ; Zoonoses ; Uveitis, Anterior/diagnosis ; Eye
    Language English
    Publishing date 2023-02-17
    Publishing country England
    Document type Case Reports ; Journal Article
    ZDB-ID 1193873-0
    ISSN 1744-5078 ; 0927-3948
    ISSN (online) 1744-5078
    ISSN 0927-3948
    DOI 10.1080/09273948.2023.2174884
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  6. Article ; Online: Vitreoretinal Surgery in Uveitis: From Old to New Concepts - A Review.

    Mazzeo, Thiago José Muniz Machado / Cristina Mendonça Freire, Raimunda / Guimarães Machado, Cleide / Gomes, André Marcelo Vieira / Curi, André Luiz Land

    Ocular immunology and inflammation

    2023  , Page(s) 1–14

    Abstract: Purpose: The aim of this article is to do a comprehensive literature review about the current role of pars plana vitrectomy in uveitis and in its different structural complications such as cystoid macular edema, epiretinal membrane, macular hole, and ... ...

    Abstract Purpose: The aim of this article is to do a comprehensive literature review about the current role of pars plana vitrectomy in uveitis and in its different structural complications such as cystoid macular edema, epiretinal membrane, macular hole, and retinal detachment.
    Methods: This comprehensive literature review was performed based on a search on PubMed, BioMed Central, Science Open, and CORE databases, of relevant articles abording pars plana vitrectomy in uveitis.
    Discussion: Uveitis is a complex disease with multiple etiologies and pathogenic mechanisms. Therapeutic pars plana vitrectomy (PPV) may aid in uveitic structural complications such as cystoid macular edema, epiretinal membranes, macular hole, and retinal detachments even though some cases may present unpredictable visual outcomes. Diagnostic PPV with appropriate ancillary testing is also a valuable tool for the assessment and diagnosis of uveitis in a large proportion of patients.
    Conclusion: Over the years, pars plana vitrectomy has undergone significant transformations since its invention nearly 5 decades ago, however, the quality of evidence in the literature regarding its use for uveitis has not improved in the same way. Even though some structural uveitis complications (as previously mentioned) may respond well to surgery, there is still a certain unpredictability regarding its visual outcomes. On the other hand, diagnostic vitrectomy with appropriate ancillary testing is also a valuable tool for the assessment and diagnosis of uveitis in a large proportion of patients.
    Language English
    Publishing date 2023-04-24
    Publishing country England
    Document type Journal Article
    ZDB-ID 1193873-0
    ISSN 1744-5078 ; 0927-3948
    ISSN (online) 1744-5078
    ISSN 0927-3948
    DOI 10.1080/09273948.2023.2193842
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  7. Article ; Online: Acute ocular toxoplasmosis presenting as a retinal angiomatous lesion.

    Pedroso, Leticia Alcântara / Costa, Flavia Veiga / Silva, Amanda Gomes E / Silva, Juliana Rocha de Mendonça da / Biancardi, Ana Luiza / Curi, André Luiz Land

    Arquivos brasileiros de oftalmologia

    2023  Volume 86, Issue 3, Page(s) 294

    MeSH term(s) Humans ; Toxoplasmosis, Ocular/complications ; Toxoplasmosis, Ocular/diagnosis ; Toxoplasmosis, Ocular/pathology ; Fluorescein Angiography
    Language English
    Publishing date 2023-06-02
    Publishing country Brazil
    Document type Letter
    ZDB-ID 603915-7
    ISSN 1678-2925 ; 0004-2749
    ISSN (online) 1678-2925
    ISSN 0004-2749
    DOI 10.5935/0004-2749.2023-0053
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  8. Article ; Online: Presumed endogenous fungal endophthalmitis in a patient with lymphopenia and confirmed SARS-CoV-2 infection.

    Carvalho, Erika Moreira / Santos, Nathalia Silva / Paiva, Alexandre de Carvalho Mendes / Teixeira, Fernando Henrique Flores / Biancardi, Ana Luiza / Curi, André Luiz Land

    Arquivos brasileiros de oftalmologia

    2023  Volume 86, Issue 2, Page(s) 190–191

    MeSH term(s) Humans ; COVID-19/complications ; SARS-CoV-2 ; Antifungal Agents/therapeutic use ; Endophthalmitis/microbiology ; Lymphopenia/complications ; Lymphopenia/drug therapy ; Eye Infections, Fungal/drug therapy
    Chemical Substances Antifungal Agents
    Language English
    Publishing date 2023-05-01
    Publishing country Brazil
    Document type Letter
    ZDB-ID 603915-7
    ISSN 1678-2925 ; 0004-2749
    ISSN (online) 1678-2925
    ISSN 0004-2749
    DOI 10.5935/0004-2749.2022-0203
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  9. Article ; Online: Optical coherence tomography findings in fungal uveitis.

    Teixeira, Fernando Henrique Flores / Santos, Nathalia Silva / de Carvalho Mendes Paiva, Alexandre / Carvalho, Erika Moreira / Biancardi, Ana Luiza / Curi, André Luiz Land

    International ophthalmology

    2023  Volume 43, Issue 8, Page(s) 3023–3030

    Abstract: Purpose: The purpose of the study was to describe the vitreal, retinal, and choroidal features of eyes affected by endogenous endophthalmitis (EE) and evaluate the effects of systemic antifungal drug treatment and pars plana vitrectomy by using spectral ...

    Abstract Purpose: The purpose of the study was to describe the vitreal, retinal, and choroidal features of eyes affected by endogenous endophthalmitis (EE) and evaluate the effects of systemic antifungal drug treatment and pars plana vitrectomy by using spectral domain optical coherence tomography (SD-OCT).
    Methods: Medical records and SD-OCT images of eyes diagnosed with EE at a single uveitis tertiary referral center in Brazil were acquired at the time of diagnosis, after 7 days of high-dose antifungal drug treatment, and at follow-up assessments performed 30 days after resolution.
    Results: Thirteen eyes were enrolled in the study. All patients showed hyperreflective round-shaped lesions on SD-OCT and pre-retinal aggregates. Five eyes responded to antifungal systemic oral drugs despite showing vitreous opacity. The response to treatment was observable on optical coherence tomography (OCT) images.
    Conclusion: Fungal endophthalmitis showed typical features on SD-OCT, facilitating early diagnosis and treatment despite the absence of vitreous culture or biopsy. This study suggests that OCT images can be used to support diagnosis by physicians who do not have access to vitreoretinal surgery.
    MeSH term(s) Humans ; Tomography, Optical Coherence/methods ; Antifungal Agents ; Uveitis/diagnosis ; Uveitis/surgery ; Endophthalmitis/diagnosis ; Vitrectomy/methods ; Retrospective Studies
    Chemical Substances Antifungal Agents
    Language English
    Publishing date 2023-04-01
    Publishing country Netherlands
    Document type Journal Article ; Review
    ZDB-ID 800087-6
    ISSN 1573-2630 ; 0165-5701
    ISSN (online) 1573-2630
    ISSN 0165-5701
    DOI 10.1007/s10792-023-02696-0
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Different clinical manifestations of ocular sporotrichosis in the same patient: an alert to ophthalmologists in nonendemic areas.

    Paiva, Alexandre de Carvalho Mendes / Biancardi, Ana Luiza / Curi, André Luiz Land

    Arquivos brasileiros de oftalmologia

    2020  Volume 83, Issue 5, Page(s) 457–458

    MeSH term(s) Antifungal Agents/therapeutic use ; Humans ; Ophthalmologists ; Sporotrichosis/diagnosis ; Sporotrichosis/drug therapy
    Chemical Substances Antifungal Agents
    Language English
    Publishing date 2020-10-20
    Publishing country Brazil
    Document type Letter
    ZDB-ID 603915-7
    ISSN 1678-2925 ; 0004-2749
    ISSN (online) 1678-2925
    ISSN 0004-2749
    DOI 10.5935/0004-2749.20200107
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