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  1. Book: Hematological malignancies

    Czader, Magdalena

    (Methods in molecular biology ; 999 ; Springer protocols)

    2013  

    Author's details ed. by Magdalena Czader
    Series title Methods in molecular biology ; 999
    Springer protocols
    Collection
    Language English
    Size X, 304 S. : Ill., graph. Darst.
    Publisher Springer
    Publishing place New York u.a.
    Publishing country United States
    Document type Book
    HBZ-ID HT017668975
    ISBN 978-1-62703-356-5 ; 9781627033572 ; 1-62703-356-4 ; 1627033572
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    2013 A 1243 available for loan (reading room) Lesesaal EG

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  2. Article ; Online: How I Diagnose.

    Siddon, Alexa J / Czader, Magdalena

    American journal of clinical pathology

    2020  Volume 154, Issue 1, Page(s) 4

    MeSH term(s) Humans ; Myelodysplastic Syndromes
    Language English
    Publishing date 2020-05-27
    Publishing country England
    Document type Journal Article ; Comment
    ZDB-ID 2944-0
    ISSN 1943-7722 ; 0002-9173
    ISSN (online) 1943-7722
    ISSN 0002-9173
    DOI 10.1093/ajcp/aqaa034
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

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  3. Article ; Online: A familial

    Rahim, Mahvish Q / Rahrig, April / Overholt, Kathleen / Conboy, Erin / Czader, Magdalena / Saraf, Amanda June

    Cold Spring Harbor molecular case studies

    2023  Volume 9, Issue 2

    Abstract: Myelodysplastic syndrome (MDS) is a rare pediatric diagnosis characterized by ineffective hematopoiesis with potential to evolve into acute myelogenous leukemia (AML). In this report, we describe a unique case of a 17-yr-old female with an aggressive ... ...

    Abstract Myelodysplastic syndrome (MDS) is a rare pediatric diagnosis characterized by ineffective hematopoiesis with potential to evolve into acute myelogenous leukemia (AML). In this report, we describe a unique case of a 17-yr-old female with an aggressive course of MDS with excess blasts who was found to have monosomy 7 and a
    MeSH term(s) Female ; Humans ; Chromosome Deletion ; Germ-Line Mutation ; Intracellular Signaling Peptides and Proteins/genetics ; Myelodysplastic Syndromes/diagnosis ; Myelodysplastic Syndromes/genetics ; Phenotype ; Adolescent
    Chemical Substances Intracellular Signaling Peptides and Proteins ; SAMD9 protein, human
    Language English
    Publishing date 2023-05-09
    Publishing country United States
    Document type Case Reports ; Journal Article
    ZDB-ID 2835759-0
    ISSN 2373-2873 ; 2373-2873
    ISSN (online) 2373-2873
    ISSN 2373-2873
    DOI 10.1101/mcs.a006256
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Fifth Edition of the World Health Organization Classification of Tumors of the Hematopoietic and Lymphoid Tissues: Acute Lymphoblastic Leukemias, Mixed-Phenotype Acute Leukemias, Myeloid/Lymphoid Neoplasms With Eosinophilia, Dendritic/Histiocytic Neoplasms, and Genetic Tumor Syndromes.

    Choi, John K / Xiao, Wenbin / Chen, Xueyan / Loghavi, Sanam / Elenitoba-Johnson, Kojo S / Naresh, Kikkeri N / Medeiros, L Jeffrey / Czader, Magdalena

    Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc

    2024  Volume 37, Issue 5, Page(s) 100466

    Abstract: This manuscript represents a review of lymphoblastic leukemia/lymphoma (acute lymphoblastic leukemia/lymphoblastic lymphoma), acute leukemias of ambiguous lineage, mixed-phenotype acute leukemias, myeloid/lymphoid neoplasms with eosinophilia and defining ...

    Abstract This manuscript represents a review of lymphoblastic leukemia/lymphoma (acute lymphoblastic leukemia/lymphoblastic lymphoma), acute leukemias of ambiguous lineage, mixed-phenotype acute leukemias, myeloid/lymphoid neoplasms with eosinophilia and defining gene rearrangements, histiocytic and dendritic neoplasms, and genetic tumor syndromes of the 5th edition of the World Health Organization Classification of Tumors of the Hematopoietic and Lymphoid Tissues. The diagnostic, clinicopathologic, cytogenetic, and molecular genetic features are discussed. The differences in comparison to the 4th revised edition of the World Health Organization classification of hematolymphoid neoplasms are highlighted.
    Language English
    Publishing date 2024-03-07
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 645073-8
    ISSN 1530-0285 ; 0893-3952
    ISSN (online) 1530-0285
    ISSN 0893-3952
    DOI 10.1016/j.modpat.2024.100466
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 2450: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  5. Book: Hematological malignancies

    Czader, Magdalena

    (Methods in Molecular Biology, ; 999 ; Springer protocols)

    2013  

    Author's details edited by Magdalena Czader
    Series title Methods in Molecular Biology, ; 999
    Springer protocols
    MeSH term(s) Hematologic Neoplasms/diagnosis ; Molecular Diagnostic Techniques/methods
    Language English
    Size x, 304 p. :, ill. (some col.), cm.
    Publisher Humana Press ; Springer
    Publishing place New York
    Document type Book
    ISBN 1627033564 ; 9781627033565 ; 9781627033572 ; 1627033572
    Database Catalogue of the US National Library of Medicine (NLM)

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  6. Article ; Online: Focused reviews of practical flow cytometry applications in hematopathology.

    Wang, Sa A / Czader, Magdalena B

    Cytometry. Part B, Clinical cytometry

    2018  Volume 96, Issue 1, Page(s) 19

    MeSH term(s) Flow Cytometry/methods ; Hematologic Diseases/diagnosis ; Humans ; Immunophenotyping
    Language English
    Publishing date 2018-12-13
    Publishing country United States
    Document type Editorial ; Introductory Journal Article
    ZDB-ID 2099657-3
    ISSN 1552-4957 ; 1552-4949 ; 0196-4763
    ISSN (online) 1552-4957
    ISSN 1552-4949 ; 0196-4763
    DOI 10.1002/cyto.b.21758
    Database MEDical Literature Analysis and Retrieval System OnLINE

    Full text online

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1688: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  7. Article ; Online: Cold agglutinin-mediated autoimmune haemolytic anaemia associated with diffuse large B cell lymphoma.

    Wongsaengsak, Sariya / Czader, Magdalena / Suvannasankha, Attaya

    BMJ case reports

    2018  Volume 2018

    Abstract: Cold agglutinin-mediated autoimmune haemolytic anaemia is associated with the development of autoantibodies that can agglutinate red blood cells at cold temperatures. While primary cold agglutinin disease is an idiopathic lymphoproliferative disorder, ... ...

    Abstract Cold agglutinin-mediated autoimmune haemolytic anaemia is associated with the development of autoantibodies that can agglutinate red blood cells at cold temperatures. While primary cold agglutinin disease is an idiopathic lymphoproliferative disorder, secondary cold agglutinin syndrome (CAS) complicates other diseases such as infections, autoimmune diseases and cancers, mostly low-grade lymphomas. Early recognition, treatment of CAS and treatment of its associated underlying diseases are crucial to a successful outcome. We report a case of CAS in a setting of diffuse large B cell lymphoma, in which the treatment course was complicated by worsened anaemia due to chemotherapy-induced myelosuppression. We reviewed previously reported cases and discussed diagnosis and treatment strategies, including novel complement inhibitors, as potential future therapy.
    MeSH term(s) Aged ; Anemia, Hemolytic, Autoimmune/blood ; Anemia, Hemolytic, Autoimmune/complications ; Anemia, Hemolytic, Autoimmune/diagnosis ; Female ; Humans ; Lymphoma, Large B-Cell, Diffuse/blood ; Lymphoma, Large B-Cell, Diffuse/complications ; Lymphoma, Large B-Cell, Diffuse/therapy
    Language English
    Publishing date 2018-07-10
    Publishing country England
    Document type Case Reports ; Journal Article
    ISSN 1757-790X
    ISSN (online) 1757-790X
    DOI 10.1136/bcr-2017-222064
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Acute Myeloid Leukemia and Other Types of Disease Progression in Myeloproliferative Neoplasms.

    Czader, Magdalena / Orazi, Attilio

    American journal of clinical pathology

    2015  Volume 144, Issue 2, Page(s) 188–206

    Abstract: Objectives: This session of the Society for Hematopathology/European Association for Haematopathology workshop focused on disease progression in myeloproliferative neoplasms (MPNs).: Methods: The session included typical and unusual presentations of ... ...

    Abstract Objectives: This session of the Society for Hematopathology/European Association for Haematopathology workshop focused on disease progression in myeloproliferative neoplasms (MPNs).
    Methods: The session included typical and unusual presentations of chronic myelogenous leukemia (CML), BCR-ABL1 positive; Philadelphia chromosome-negative (Ph-neg) MPNs; and mastocytosis.
    Results: Cases of CML illustrated various manifestations of progression, with emphasis on criteria defining stages of the disease. Issues were discussed related to the patterns of recurrence in patients receiving tyrosine kinase inhibitor therapy, including leukemic transformation occurring in a Ph-neg clone. Ph-neg MPN cases highlighted diagnostic approaches used to establish accelerated and blast phases, including cases with significant myelofibrosis and when an adequate bone marrow aspirate smear is not available. The session also included rare cases of aggressive mastocytosis.
    Conclusions: There was agreement that a definitive diagnosis can be challenging in the absence of documented review of prior diagnostic material and clinical history.
    MeSH term(s) Disease Progression ; Humans ; Leukemia, Myeloid, Acute/diagnosis ; Myeloproliferative Disorders/diagnosis
    Language English
    Publishing date 2015-08
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 2944-0
    ISSN 1943-7722 ; 0002-9173
    ISSN (online) 1943-7722
    ISSN 0002-9173
    DOI 10.1309/AJCPZQK40JOZZZCC
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Ud II Zs.91: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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  9. Article ; Online: Genetic Testing in the Diagnosis and Biology of Acute Leukemia.

    Harris, Marian H / Czuchlewski, David R / Arber, Daniel A / Czader, Magdalena

    American journal of clinical pathology

    2019  Volume 152, Issue 3, Page(s) 322–346

    Abstract: Objectives: The 2017 Workshop of the Society for Hematopathology/European Association for Haematopathology examined the role of molecular genetics in the diagnosis and biology of acute leukemia.: Methods: Acute leukemias were reviewed in two sessions: ...

    Abstract Objectives: The 2017 Workshop of the Society for Hematopathology/European Association for Haematopathology examined the role of molecular genetics in the diagnosis and biology of acute leukemia.
    Methods: Acute leukemias were reviewed in two sessions: "Genetic Testing in Diagnosis of Acute Leukemias" (53 cases) and "Genetics Revealing the Biology of Acute Leukemias" (41 cases).
    Results: Cases included acute lymphoblastic leukemia, acute myeloid leukemia, and acute leukemia of ambiguous lineage. Many cases demonstrated genetic alterations of known diagnostic, prognostic, and/or therapeutic significance, while others exhibited alterations that illuminated disease biology. The workshop highlighted the complexity of acute leukemia diagnosis and follow-up, while illustrating advantages and pitfalls of molecular genetic testing.
    Conclusions: Our understanding of the molecular genetics of acute leukemias continues to grow rapidly. Awareness of the potential complexity of genetic architecture and environment is critical and emphasizes the importance of integrating clinical information with morphologic, immunophenotypic, and molecular genetic evaluation.
    MeSH term(s) Genetic Testing ; Humans ; Leukemia, Biphenotypic, Acute/diagnosis ; Leukemia, Biphenotypic, Acute/genetics ; Leukemia, Biphenotypic, Acute/pathology ; Leukemia, Myeloid, Acute/diagnosis ; Leukemia, Myeloid, Acute/genetics ; Leukemia, Myeloid, Acute/pathology ; Pathology, Molecular ; Precursor Cell Lymphoblastic Leukemia-Lymphoma/diagnosis ; Precursor Cell Lymphoblastic Leukemia-Lymphoma/genetics ; Precursor Cell Lymphoblastic Leukemia-Lymphoma/pathology
    Language English
    Publishing date 2019-07-18
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 2944-0
    ISSN 1943-7722 ; 0002-9173
    ISSN (online) 1943-7722
    ISSN 0002-9173
    DOI 10.1093/ajcp/aqz093
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Ud II Zs.91: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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  10. Article ; Online: Transformations of marginal zone lymphomas and lymphoplasmacytic lymphomas: Report from the 2021 SH/EAHP Workshop.

    Cook, James R / Amador, Catalina / Czader, Magdalena / Duffield, Amy / Goodlad, John / Ott, German / Xiao, Wenbin / Dave, Sandeep / Thakkar, Devang / Thacker, Elizabeth / Dogan, Ahmet / Wasik, Mariusz / Nejati, Reza

    American journal of clinical pathology

    2023  

    Abstract: Objectives: To summarize the conclusions of the 2021 Society for Hematopathology/European Association for Haematopathology workshop regarding transformations of marginal zone lymphoma (MZL) and lymphoplasmacytic lymphoma (LPL).: Methods: Nineteen ... ...

    Abstract Objectives: To summarize the conclusions of the 2021 Society for Hematopathology/European Association for Haematopathology workshop regarding transformations of marginal zone lymphoma (MZL) and lymphoplasmacytic lymphoma (LPL).
    Methods: Nineteen cases were submitted to this portion of the workshop. Additional studies were performed in cases with sufficient material.
    Results: Cases included splenic MZL (n = 4), splenic diffuse red pulp small B-cell lymphoma (n = 2), nodal MZL (n = 4), extranodal MZL (n = 1), and LPL (n = 8). The most common transformation was to diffuse large B-cell lymphoma (DLBCL), but others included classic Hodgkin lymphoma, high-grade B-cell lymphomas with MYC and BCL6 rearrangements, plasmablastic lymphoma, and plasma cell leukemia. Two splenic MZLs with transformation to DLBCL contained t(14;19)(q32;q13.3) IGH::BCL3 rearrangements in both samples. Paired sequencing studies in 5 MZLs with transformation to clonally related DLBCL identified a variety of mutations and gene fusions at the time of transformation, including CARD11, IGH::MYC, NOTCH2, P2RY8, TBLX1X1, and IGH::CD274.
    Conclusions: Marginal zone lymphoma and LPL may undergo a variety of transformation events, most commonly to DLBCL, which is usually, although not always, directly clonally related to the underlying low-grade lymphoma. Multiparameter analysis including broad-based sequencing studies can assist in the diagnosis and classification of these uncommon cases.
    Language English
    Publishing date 2023-04-26
    Publishing country England
    Document type Journal Article
    ZDB-ID 2944-0
    ISSN 1943-7722 ; 0002-9173
    ISSN (online) 1943-7722
    ISSN 0002-9173
    DOI 10.1093/ajcp/aqad034
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Ud II Zs.91: Show issues Location:
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