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  1. Article ; Online: Cervical and Oropharyngeal Lymphogranuloma Venereum: Case Report and Literature Review.

    Galeano-Valle, Francisco / Pérez-Latorre, Leire / Díez-Romero, Cristina / Fanciulli, Chiara / Aldamiz-Echeverria-Lois, Teresa / Tejerina-Picado, Francisco

    Sexually transmitted diseases

    2019  Volume 46, Issue 10, Page(s) 689–692

    Abstract: Lymphogranuloma venereum (LGV) is a sexually transmitted infection caused by invasive serovars of Chlamydia trachomatis. There have been only a few case reports of oropharyngeal C. trachomatis infection complicated with cervical LGV. We report a case of ... ...

    Abstract Lymphogranuloma venereum (LGV) is a sexually transmitted infection caused by invasive serovars of Chlamydia trachomatis. There have been only a few case reports of oropharyngeal C. trachomatis infection complicated with cervical LGV. We report a case of a HIV-positive male patient with cervical LGV that presented a poor evolution despite appropriate treatment.
    MeSH term(s) Anti-Bacterial Agents/therapeutic use ; Cervical Atlas/microbiology ; Chlamydia Infections/complications ; Chlamydia Infections/microbiology ; Chlamydia trachomatis ; HIV Infections/complications ; HIV Infections/drug therapy ; HIV Infections/microbiology ; HIV Seropositivity/complications ; HIV Seropositivity/microbiology ; Homosexuality, Male ; Humans ; Lymphogranuloma Venereum/diagnostic imaging ; Lymphogranuloma Venereum/drug therapy ; Male ; Middle Aged ; Oropharynx/microbiology ; Serogroup ; Tomography, X-Ray Computed
    Chemical Substances Anti-Bacterial Agents
    Language English
    Publishing date 2019-06-27
    Publishing country United States
    Document type Case Reports ; Journal Article ; Review
    ZDB-ID 435191-5
    ISSN 1537-4521 ; 0148-5717
    ISSN (online) 1537-4521
    ISSN 0148-5717
    DOI 10.1097/OLQ.0000000000001036
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Virological outcome among HIV infected patients transferred from pediatric care to adult units in Madrid, Spain (1997-2017).

    Beltrán-Pavez, Carolina / Gutiérrez-López, Miguel / Rubio-Garrido, Marina / Valadés-Alcaraz, Ana / Prieto, Luis / Ramos, José Tomás / Jiménez De Ory, Santiago / Navarro, Marisa / Díez-Romero, Cristina / Pulido, Federico / Valencia, Eulalia / Holguín, África

    Scientific reports

    2020  Volume 10, Issue 1, Page(s) 16891

    Abstract: The aim of this transversal study was to describe the virological and immunological features of HIV-infected youths transferred from pediatric to adult care units since 1997 vs. the non-transferred patients from the Madrid Cohort of HIV-infected children ...

    Abstract The aim of this transversal study was to describe the virological and immunological features of HIV-infected youths transferred from pediatric to adult care units since 1997 vs. the non-transferred patients from the Madrid Cohort of HIV-infected children and adolescents in Spain. We included 106 non-transferred and 184 transferred patients under clinical follow-up in 17 public hospitals in Madrid by the end of December 2017. Virological and immunological outcomes were compared in transferred vs. non-transferred patients. ART drug resistance mutations and HIV-variants were analyzed in all subjects with available resistance pol genotypes and/or genotypic resistance profiles. Among the study cohort, 133 (72.3%) of 184 transferred and 75 (70.7%) of 106 non-transferred patients had available resistance genotypes. Most (88.9%) of transferred had ART experience at sampling. A third (33.3%) had had a triple-class experience. Acquired drug resistance (ADR) prevalence was significantly higher in pretreated transferred than non-transferred patients (71.8% vs. 44%; p = 0.0009), mainly to NRTI (72.8% vs. 31.1%; p < 0.0001) and PI (29.1% vs. 12%; p = 0.0262). HIV-1 non-B variants were less frequent in transferred vs. non-transferred (6.9% vs. 32%; p < 0.0001). In conclusion, the frequent resistant genotypes found in transferred youths justifies the reinforcement of HIV resistance monitoring after the transition to avoid future therapeutic failures.
    MeSH term(s) Adolescent ; Adult ; Anti-HIV Agents/therapeutic use ; Child ; Child, Preschool ; Cohort Studies ; Drug Resistance, Viral/genetics ; Female ; Genotype ; HIV Infections/drug therapy ; HIV Infections/genetics ; HIV Infections/virology ; HIV-1/drug effects ; HIV-1/genetics ; Humans ; Infant ; Male ; Mutation/genetics ; Pediatrics ; Spain ; Viral Load/genetics ; Young Adult
    Chemical Substances Anti-HIV Agents
    Language English
    Publishing date 2020-10-09
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2615211-3
    ISSN 2045-2322 ; 2045-2322
    ISSN (online) 2045-2322
    ISSN 2045-2322
    DOI 10.1038/s41598-020-70861-x
    Database MEDical Literature Analysis and Retrieval System OnLINE

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