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  1. Book: Leitsymptombasierte Notfallmedizin

    Dünser, Martin W. / Klinglmair, M. / Eisenburger, P. / Gotterbarm, Tobias / Neuner, M. / Valentin, Andreas / Vosko, M.

    Akut- und Notfälle präzise diagnostizieren und richtig behandeln : ein Wissenskompendium und Praxishandbuch

    2023  

    Author's details M. Dünser, M. Klinglmair, P. Eisenburger, T. Gotterbarm, M. Neuner, A. Valentin, M. Vosko
    Keywords Diagnostizieren ; Differentialdiagnosen ; Zeitersparnis ; Notfälle ; Akutfälle ; Praxisnah
    Language German
    Size 768 Seiten, Illustrationen, 24 cm x 17 cm
    Publisher Trauner
    Publishing place Linz
    Publishing country Austria
    Document type Book
    Note Zugang zur Online-Ausgabe über Code
    HBZ-ID HT021730084
    ISBN 978-3-99113-324-7 ; 3-99113-324-5
    Database Catalogue ZB MED Medicine, Health

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  2. Article ; Online: Pestiviren bei Schafen und Ziegen in ­Österreich: Möglichkeiten zur ­Einbindung in die BVDV-Überwachung.

    Sailer, A / Wallner, A / Haidegger, M / Dünser, M

    Schweizer Archiv fur Tierheilkunde

    2023  Volume 165, Issue 12, Page(s) 783–791

    Abstract: Introduction: After the successful eradication of the bovine viral diarrhea virus (BVDV) in cattle in Austria, the risk of infections with the border disease virus (BDV) remains. Both viruses belong to the pestivirus genus. BDV infections lead to false- ... ...

    Title translation Pestiviruses in sheep and goats in Austria: Options for integration into the bovine viral diarrhea (BVDV) monitoring program.
    Abstract Introduction: After the successful eradication of the bovine viral diarrhea virus (BVDV) in cattle in Austria, the risk of infections with the border disease virus (BDV) remains. Both viruses belong to the pestivirus genus. BDV infections lead to false-positive results in BVDV surveillance. This can be attributed to the contact to small ruminant populations. In particular, keeping cattle together with sheep or goats on a farm or alpine pasture are significant risk factors. Between 2015 and 2022, BDV type 3 was detected in 15 cattles in Austria. These animals were almost exclusively persistently infected calves. However, a positive antibody result for pestiviruses can lead to an extremely time-consuming and costly, and not always successful search for the source of the infection if no active virus excretor is found. This study documents how small ruminants can be integrated into pestivirus monitoring with a manageable amount of work and costs. 23 406 sheep and goat samples from two brucellosis surveillance programs in small ruminants were analyzed retrospectively. Blood samples were examined using pestivirus real-time pool RT-PCR (qPCR). Direct virus detection of BDV-3 was achieved in 40 sheep from five different federal states. Over the entire investigation period a further 37 detections of BDV-3 were found in cattle, sheep and goats outside of this study throughout Austria. This study accounts for 52 % of all border disease detections from 2015 to 2022. By including small ruminants in pestivirus monitoring, the disruptive factor BDV and the risk of its introduction into cattle herds can be significantly minimized in the future.
    MeSH term(s) Animals ; Sheep ; Cattle ; Pestivirus/genetics ; Goats ; Austria/epidemiology ; Retrospective Studies ; Pestivirus Infections/epidemiology ; Pestivirus Infections/veterinary ; Border disease virus ; Diarrhea/veterinary ; Goat Diseases/epidemiology
    Language German
    Publishing date 2023-07-14
    Publishing country Switzerland
    Document type English Abstract ; Journal Article
    ZDB-ID 391726-5
    ISSN 1664-2848 ; 0036-7281
    ISSN (online) 1664-2848
    ISSN 0036-7281
    DOI doi.org/10.17236/sat00413
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Self-harm and poisoning data in rural Ugandan hospitals - a reply.

    Duenser, M

    Anaesthesia

    2016  Volume 72, Issue 5, Page(s) 665–666

    MeSH term(s) Self-Injurious Behavior
    Language English
    Publishing date 2016-02-04
    Publishing country England
    Document type Letter ; Comment
    ZDB-ID 80033-8
    ISSN 1365-2044 ; 0003-2409
    ISSN (online) 1365-2044
    ISSN 0003-2409
    DOI 10.1111/anae.13887
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Anamnese und klinische Untersuchung in der Notfall- und Intensivmedizin.

    Steinkellner, C / Schlömmer, C / Dünser, M

    Medizinische Klinik, Intensivmedizin und Notfallmedizin

    2020  Volume 115, Issue 7, Page(s) 530–538

    Abstract: Medical history taking and the clinical examination are the traditional medical tools in making a diagnosis. Both the medical history taking and clinical examination have wrongly lost their practical value in modern emergency and intensive care medicine. ...

    Title translation Medical history taking and clinical examination in emergency and intensive care medicine.
    Abstract Medical history taking and the clinical examination are the traditional medical tools in making a diagnosis. Both the medical history taking and clinical examination have wrongly lost their practical value in modern emergency and intensive care medicine. When diagnosing an acutely or critically ill patient, the sequence, technique and focus of history taking and the clinical examination must be adapted to the individual situation and the condition of the patient. In this article the continuing central importance of both techniques in the diagnostics of emergency and intensive care patients is practically evaluated and discussed.
    MeSH term(s) Critical Care ; Critical Illness/therapy ; Emergency Medicine ; Emergency Service, Hospital ; Humans ; Medical History Taking ; Physical Examination
    Language German
    Publishing date 2020-09-03
    Publishing country Germany
    Document type Journal Article ; Review
    ZDB-ID 2636018-4
    ISSN 2193-6226 ; 1435-1420 ; 0723-5003 ; 2193-6218 ; 0175-3851
    ISSN (online) 2193-6226 ; 1435-1420
    ISSN 0723-5003 ; 2193-6218 ; 0175-3851
    DOI 10.1007/s00063-020-00731-x
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Angiotensin II als alternativer nichtadrenerger Vasopressor : Ergebnisse einer randomisierten doppelblinden placebokontrollierten Effektivitätsstudie.

    Dünser, M / Meier, J

    Medizinische Klinik, Intensivmedizin und Notfallmedizin

    2017  Volume 112, Issue 6, Page(s) 540–542

    Title translation Angiotensin II as an alternative nonadrenergic vasopressor : Results of a randomized, double-blind, placebo-controlled efficacy study.
    Language German
    Publishing date 2017-09
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 2636018-4
    ISSN 2193-6226 ; 1435-1420 ; 0723-5003 ; 2193-6218 ; 0175-3851
    ISSN (online) 2193-6226 ; 1435-1420
    ISSN 0723-5003 ; 2193-6218 ; 0175-3851
    DOI 10.1007/s00063-017-0319-4
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: Mycobacterium avium

    Schrott, Juliane / Sodoma, Eva / Dünser, Michael / Tichy, Alexander / Khol, Johannes Lorenz

    Animals : an open access journal from MDPI

    2023  Volume 13, Issue 9

    Abstract: This study aimed to investigate the prevalence ... ...

    Abstract This study aimed to investigate the prevalence of
    Language English
    Publishing date 2023-04-30
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2606558-7
    ISSN 2076-2615
    ISSN 2076-2615
    DOI 10.3390/ani13091517
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: RBC Transfusion Triggers: Is There Anything New?

    Tomic Mahecic, Tina / Dünser, Martin / Meier, Jens

    Transfusion medicine and hemotherapy : offizielles Organ der Deutschen Gesellschaft fur Transfusionsmedizin und Immunhamatologie

    2020  Volume 47, Issue 5, Page(s) 361–368

    Abstract: For many years, in daily clinical practice, the traditional 10/30 rule (hemoglobin 10 g/dL - hematocrit 30%) has been the most commonly used trigger for blood transfusions. Over the years, this approach is believed to have contributed to a countless ... ...

    Abstract For many years, in daily clinical practice, the traditional 10/30 rule (hemoglobin 10 g/dL - hematocrit 30%) has been the most commonly used trigger for blood transfusions. Over the years, this approach is believed to have contributed to a countless number of unnecessary transfusions and an unknown number of overtransfusion-related deaths. Recent studies have shown that lower hemoglobin levels can safely be accepted, even in critically ill patients. However, even these new transfusion thresholds are far beyond the theoretical limits of individual anemia tolerance. For this reason, almost all publications addressing the limits of acute anemia recommend physiological transfusion triggers to indicate the transfusion of erythrocyte concentrates as an alternative. Although this concept appears intuitive at first glance, no solid scientific evidence supports the safety and benefit of physiological transfusion triggers to indicate the optimal time point for transfusion of allogeneic blood. It is therefore imperative to continue searching for the most sensitive and specific parameters that can guide the clinician when to transfuse in order to avoid anemia-induced organ dysfunction while avoiding overtransfusion-related adverse effects. This narrative review discusses the concept of anemia tolerance and critically compares hemoglobin-based triggers with physiological transfusion for various clinical indications.
    Language English
    Publishing date 2020-09-24
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2100848-6
    ISSN 1660-3818 ; 1660-3796
    ISSN (online) 1660-3818
    ISSN 1660-3796
    DOI 10.1159/000511229
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Diagnostik der akuten Organischämie : Eine Praxisanleitung für Notfall- und Intensivmediziner.

    Szasz, Johannes / Noitz, Matthias / Dünser, Martin

    Medizinische Klinik, Intensivmedizin und Notfallmedizin

    2020  Volume 115, Issue 2, Page(s) 159–172

    Abstract: Ischemia refers to a reduction or interruption of the blood flow to one or more organs. Early recognition of shock, a global ischemic state of the body, is of key importance in emergency and intensive care medicine. The physical examination and point-of- ... ...

    Title translation Diagnosing acute organ ischemia : A practical guide for the emergency and intensive care physician.
    Abstract Ischemia refers to a reduction or interruption of the blood flow to one or more organs. Early recognition of shock, a global ischemic state of the body, is of key importance in emergency and intensive care medicine. The physical examination and point-of-care laboratory diagnostics (i.e. lactate, base deficit, central/mixed venous oxygen saturation, venous-arterial carbon dioxide partial tension) are the methods of choice to diagnose shock in clinical practice. Importantly, a state of shock can also be present in patients with normo- or hypertensive arterial blood pressures. In shock, hypoperfusion of vital and visceral organs occurs. In the second part of this article, physical examination techniques, laboratory and diagnostic methods to detect shock-related hypoperfusion of the brain, heart, kidney and gastrointestinal tract are reviewed.
    MeSH term(s) Blood Gas Analysis ; Carbon Dioxide ; Critical Care ; Emergency Service, Hospital ; Humans ; Ischemia/diagnosis ; Oxygen ; Shock
    Chemical Substances Carbon Dioxide (142M471B3J) ; Oxygen (S88TT14065)
    Language German
    Publishing date 2020-02-21
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 2636018-4
    ISSN 2193-6226 ; 1435-1420 ; 0723-5003 ; 2193-6218 ; 0175-3851
    ISSN (online) 2193-6226 ; 1435-1420
    ISSN 0723-5003 ; 2193-6218 ; 0175-3851
    DOI 10.1007/s00063-020-00655-6
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Machine Learning Prediction of SARS-CoV-2 Polymerase Chain Reaction Results with Routine Blood Tests.

    Tschoellitsch, Thomas / Dünser, Martin / Böck, Carl / Schwarzbauer, Karin / Meier, Jens

    Laboratory medicine

    2020  Volume 52, Issue 2, Page(s) 146–149

    Abstract: Objective: The diagnosis of COVID-19 is based on the detection of SARS-CoV-2 in respiratory secretions, blood, or stool. Currently, reverse transcription polymerase chain reaction (RT-PCR) is the most commonly used method to test for SARS-CoV-2.: ... ...

    Abstract Objective: The diagnosis of COVID-19 is based on the detection of SARS-CoV-2 in respiratory secretions, blood, or stool. Currently, reverse transcription polymerase chain reaction (RT-PCR) is the most commonly used method to test for SARS-CoV-2.
    Methods: In this retrospective cohort analysis, we evaluated whether machine learning could exclude SARS-CoV-2 infection using routinely available laboratory values. A Random Forests algorithm with 28 unique features was trained to predict the RT-PCR results.
    Results: Out of 12,848 patients undergoing SARS-CoV-2 testing, routine blood tests were simultaneously performed in 1357 patients. The machine learning model could predict SARS-CoV-2 test results with an accuracy of 86% and an area under the receiver operating characteristic curve of 0.74.
    Conclusion: Machine learning methods can reliably predict a negative SARS-CoV-2 RT-PCR test result using standard blood tests.
    MeSH term(s) Adult ; Aged ; Aged, 80 and over ; COVID-19/blood ; COVID-19 Nucleic Acid Testing ; Female ; Humans ; Machine Learning ; Male ; Middle Aged ; Retrospective Studies ; SARS-CoV-2/isolation & purification ; Sensitivity and Specificity
    Language English
    Publishing date 2020-12-18
    Publishing country England
    Document type Journal Article
    ZDB-ID 391758-7
    ISSN 1943-7730 ; 0007-5027
    ISSN (online) 1943-7730
    ISSN 0007-5027
    DOI 10.1093/labmed/lmaa111
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Die Rolle der Mikrozirkulation in der Entstehung des Organversagens.

    Noitz, Matthias / Steinkellner, Christoph / Willingshofer, Mark Philipp / Szasz, Johannes / Dünser, Martin

    Deutsche medizinische Wochenschrift (1946)

    2021  Volume 147, Issue 1-02, Page(s) 17–25

    Abstract: The microcirculation includes all blood and lymph vessels with a diameter < 100 µm. Microcirculatory dysfunction is common in critically ill patients and is closely associated with both the severity of (multi-)organ dysfunction and mortality. The nature ... ...

    Title translation The role of the microcirculation in the pathogenesis of organ dysfunction.
    Abstract The microcirculation includes all blood and lymph vessels with a diameter < 100 µm. Microcirculatory dysfunction is common in critically ill patients and is closely associated with both the severity of (multi-)organ dysfunction and mortality. The nature and extent of microcirculatory dysfunction differ depending on the underlying disease and are most pronounced in patients with systemic inflammation (e. g. sepsis), specific infections (e. g. malaria, dengue) or thrombocytopenia-associated multiple organ failure. This manuscript provides an overview of the pathophysiology, monitoring and therapy of microcirculatory dysfunction in the critically ill patient.
    MeSH term(s) Critical Illness ; Humans ; Microcirculation/physiology ; Multiple Organ Failure/physiopathology ; Vascular Diseases/physiopathology
    Language German
    Publishing date 2021-12-28
    Publishing country Germany
    Document type Journal Article ; Review
    ZDB-ID 200446-x
    ISSN 1439-4413 ; 0012-0472
    ISSN (online) 1439-4413
    ISSN 0012-0472
    DOI 10.1055/a-1226-9091
    Database MEDical Literature Analysis and Retrieval System OnLINE

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