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  1. Article ; Online: Biological effects of a copper-based fungicide on the fruit fly,

    Rieder, G S / Zamberlan, D C / Aschner, M / Silva, L F O / da Rocha, J B T

    Journal of environmental science and health. Part. B, Pesticides, food contaminants, and agricultural wastes

    2024  , Page(s) 1–9

    Abstract: The increased consumption of pesticides can have a negative environmental impact by increasing the essential metals to toxic levels. Bordasul® is a commonly used fungicide in Brazil and it is composed of 20% Cu, 10% sulfur, and 3.0% calcium. The study of ...

    Abstract The increased consumption of pesticides can have a negative environmental impact by increasing the essential metals to toxic levels. Bordasul® is a commonly used fungicide in Brazil and it is composed of 20% Cu, 10% sulfur, and 3.0% calcium. The study of fungicides
    Language English
    Publishing date 2024-05-06
    Publishing country England
    Document type Journal Article
    ZDB-ID 197072-0
    ISSN 1532-4109 ; 0360-1234
    ISSN (online) 1532-4109
    ISSN 0360-1234
    DOI 10.1080/03601234.2024.2347167
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.B 1217: Show issues Location:
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  2. Article ; Online: Toxicological and behavioral analyses indicates the safety of a biofertilizer in the non-target D. melanogaster.

    Rieder, G S / Zamberlan, D C / Silva, L F O / Borin, B C / Schuch, A P / da Rocha, J B T

    The Science of the total environment

    2023  Volume 873, Page(s) 162150

    Abstract: The demand for food to feed the growing world population has been promoting the indiscriminate use of chemical fertilizers, which can be detrimental to the environment. In order to maintain high crop productivity without damaging the ecosystem, ... ...

    Abstract The demand for food to feed the growing world population has been promoting the indiscriminate use of chemical fertilizers, which can be detrimental to the environment. In order to maintain high crop productivity without damaging the ecosystem, biofertilizers have emerged as alternative to reduce the use of chemical fertilizers. So, environmentally safer biofertilizer can replace the exploitation of more toxic chemical fertilizer. Here, the fly Drosophila melanogaster was used to study the potential toxicity of the biofertilizer Beifort®. Flies were exposed to high concentrations of Beifort® in the diet (1.8 mL/L, 9.0 mL/L and 18 mL/L), and morphological and behavioral endpoints of toxicity were analyzed (development from egg to adult age, flies longevity, climbing performance, memory and learning of an associative learning, larvae digestive tract damage and plasmid DNA break). Beifort® did not modify flies development, survival, digestive track cell damage, locomotor activity or memory. Beifort® did not induce DNA breakage in vitro and had no toxicity to the non-target D. melanogaster after in vivo exposure. Thus, in addition of promoting the sustainable use of agricultural wastes, the exploitation of Beifort® can contribute to decrease the use of chemical fertilizers.
    MeSH term(s) Animals ; Drosophila melanogaster ; Ecosystem ; Fertilizers/toxicity ; Fertilizers/analysis ; Agriculture ; Crop Production
    Chemical Substances Fertilizers
    Language English
    Publishing date 2023-02-09
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 121506-1
    ISSN 1879-1026 ; 0048-9697
    ISSN (online) 1879-1026
    ISSN 0048-9697
    DOI 10.1016/j.scitotenv.2023.162150
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Interplay between diphenyl diselenide and copper: Impact on D. melanogaster survival, behavior, and biochemical parameters.

    Rieder, G S / Duarte, T / Delgado, C P / Rodighiero, A / Nogara, P A / Orian, L / Aschner, M / Dalla Corte, C L / Da Rocha, J B T

    Comparative biochemistry and physiology. Toxicology & pharmacology : CBP

    2024  Volume 281, Page(s) 109899

    Abstract: ... Copper ( ... ...

    Abstract Copper (Cu
    MeSH term(s) Animals ; Benzene Derivatives/toxicity ; Benzene Derivatives/pharmacology ; Drosophila melanogaster/drug effects ; Organoselenium Compounds/pharmacology ; Organoselenium Compounds/toxicity ; Male ; Oxidative Stress/drug effects ; Reactive Oxygen Species/metabolism ; Behavior, Animal/drug effects ; Female ; Copper/toxicity ; Acetylcholinesterase/metabolism ; Antioxidants/metabolism ; Catalase/metabolism ; Copper Sulfate/toxicity ; Locomotion/drug effects ; Cell Survival/drug effects
    Chemical Substances diphenyldiselenide (1666-13-3) ; Benzene Derivatives ; Organoselenium Compounds ; Reactive Oxygen Species ; Copper (789U1901C5) ; Acetylcholinesterase (EC 3.1.1.7) ; Antioxidants ; Catalase (EC 1.11.1.6) ; Copper Sulfate (LRX7AJ16DT)
    Language English
    Publishing date 2024-03-20
    Publishing country United States
    Document type Journal Article
    ZDB-ID 189285-x
    ISSN 1532-0456 ; 0306-4492 ; 0742-8413
    ISSN 1532-0456 ; 0306-4492 ; 0742-8413
    DOI 10.1016/j.cbpc.2024.109899
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 44/C: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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  4. Article ; Online: Toxicological and behavioral analyses indicates the safety of a biofertilizer in the non-target D. melanogaster

    Rieder, G.S. / Zamberlan, D.C. / Silva, L.F.O. / Borin, B.C. / Schuch, A.P. / da Rocha, J.B.T.

    Science of the Total Environment. 2023 May, v. 873 p.162150-

    2023  

    Abstract: The demand for food to feed the growing world population has been promoting the indiscriminate use of chemical fertilizers, which can be detrimental to the environment. In order to maintain high crop productivity without damaging the ecosystem, ... ...

    Abstract The demand for food to feed the growing world population has been promoting the indiscriminate use of chemical fertilizers, which can be detrimental to the environment. In order to maintain high crop productivity without damaging the ecosystem, biofertilizers have emerged as alternative to reduce the use of chemical fertilizers. So, environmentally safer biofertilizer can replace the exploitation of more toxic chemical fertilizer. Here, the fly Drosophila melanogaster was used to study the potential toxicity of the biofertilizer Beifort®. Flies were exposed to high concentrations of Beifort® in the diet (1.8 mL/L, 9.0 mL/L and 18 mL/L), and morphological and behavioral endpoints of toxicity were analyzed (development from egg to adult age, flies longevity, climbing performance, memory and learning of an associative learning, larvae digestive tract damage and plasmid DNA break). Beifort® did not modify flies development, survival, digestive track cell damage, locomotor activity or memory. Beifort® did not induce DNA breakage in vitro and had no toxicity to the non-target D. melanogaster after in vivo exposure. Thus, in addition of promoting the sustainable use of agricultural wastes, the exploitation of Beifort® can contribute to decrease the use of chemical fertilizers.
    Keywords DNA damage ; Drosophila melanogaster ; adults ; biofertilizers ; diet ; digestive tract ; ecosystems ; eggs ; environment ; locomotion ; longevity ; memory ; mineral fertilizers ; plasmids ; toxic substances ; toxicity ; toxicology ; Biofertilizer ; Beifort ; Behavior ; Development
    Language English
    Dates of publication 2023-05
    Publishing place Elsevier B.V.
    Document type Article ; Online
    Note Pre-press version
    ZDB-ID 121506-1
    ISSN 1879-1026 ; 0048-9697
    ISSN (online) 1879-1026
    ISSN 0048-9697
    DOI 10.1016/j.scitotenv.2023.162150
    Database NAL-Catalogue (AGRICOLA)

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    In stock of ZB MED Bonn / Germany

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  5. Article: Copper decreases associative learning and memory in Drosophila melanogaster

    Zamberlan, D.C / da Rocha, J.B.T / Halmenschelager, P.T / Silva, L.F.O

    Science of the total environment. 2020 Mar. 25, v. 710

    2020  

    Abstract: Copper is an essential element to all living organisms. Repeated use of metal-enriched chemicals, fertilizers, and organic substances may cause contamination at a large scale. Altered levels of Cu2+ may result in harmful effects and can be associated ... ...

    Abstract Copper is an essential element to all living organisms. Repeated use of metal-enriched chemicals, fertilizers, and organic substances may cause contamination at a large scale. Altered levels of Cu2+ may result in harmful effects and can be associated with memory and cognitive dysfunction. Studying simple, genetically tractable organisms such as Drosophila melanogaster, can reveal important data on the neural basis of conditioning. D. melanogaster is an important alternative experimental model to assess the toxic response to metals. In the present study, the effects of copper on flies’ development and in learning and memory retention in male and female adult flies were investigated. We paired an odorant to pain perception and observed the aversion behavior over time. Exposure of D. melanogaster eggs to Cu2+ increased mortality of larvae, pupae, and adults and decreased memory retention in adults. Moreover, male flies demonstrated to be more susceptible to Cu2+ toxicity than females. The results therefore, reinforce the importance of controlling the anthropogenic heavy-metals soil contamination given their hazardous effects to living organisms.
    Keywords cognition ; copper ; Drosophila melanogaster ; eggs ; females ; fertilizers ; heavy metals ; imagos ; larvae ; males ; memory ; mortality ; odor compounds ; organic matter ; pain ; pupae ; soil pollution ; toxicity
    Language English
    Dates of publication 2020-0325
    Publishing place Elsevier B.V.
    Document type Article
    ZDB-ID 121506-1
    ISSN 1879-1026 ; 0048-9697
    ISSN (online) 1879-1026
    ISSN 0048-9697
    DOI 10.1016/j.scitotenv.2019.135306
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  6. Article ; Online: Copper decreases associative learning and memory in Drosophila melanogaster.

    Zamberlan, D C / Halmenschelager, P T / Silva, L F O / da Rocha, J B T

    The Science of the total environment

    2019  Volume 710, Page(s) 135306

    Abstract: Copper is an essential element to all living organisms. Repeated use of metal-enriched chemicals, fertilizers, and organic substances may cause contamination at a large scale. Altered levels of ... ...

    Abstract Copper is an essential element to all living organisms. Repeated use of metal-enriched chemicals, fertilizers, and organic substances may cause contamination at a large scale. Altered levels of Cu
    MeSH term(s) Animals ; Copper ; Drosophila melanogaster ; Female ; Larva ; Learning ; Male
    Chemical Substances Copper (789U1901C5)
    Language English
    Publishing date 2019-11-24
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 121506-1
    ISSN 1879-1026 ; 0048-9697
    ISSN (online) 1879-1026
    ISSN 0048-9697
    DOI 10.1016/j.scitotenv.2019.135306
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 949: Show issues Location:
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  7. Article: Exposure to sublethal concentrations of Zn(II) and Cu(II) changes biochemical parameters in Leporinus obtusidens.

    Gioda, C R / Lissner, L A / Pretto, A / da Rocha, J B T / Schetinger, M R C / Neto, J R / Morsch, V M / Loro, V L

    Chemosphere

    2007  Volume 69, Issue 1, Page(s) 170–175

    Abstract: The aim of the present study was to assess the effect of the exposure of Leporinus obtusidens (Piava) to zinc and copper on catalase activity in the liver, delta-aminolevulinate dehidratase (delta-ALA-D) activity in liver, muscle, brain and kidney, and ... ...

    Abstract The aim of the present study was to assess the effect of the exposure of Leporinus obtusidens (Piava) to zinc and copper on catalase activity in the liver, delta-aminolevulinate dehidratase (delta-ALA-D) activity in liver, muscle, brain and kidney, and thiobarbituric reactive species (TBARS) in brain, muscle and liver. In addition, hematological parameters were measured in blood. The fish were exposed to 10% and 20% of the derived LC(50) values, 2.3 and 4.6 mg Zn l(-1) and 0.02 and 0.04 mg Cu l(-1), and sampled on days 30 and 45. Exposure to Zn(II) and Cu(II) decreased hematological parameters and also delta-ALA-D activity mainly in liver and kidney at all concentrations tested. Liver catalase activity increased after zinc or copper exposure at all concentrations and exposure times tested. Thiobarbituric reactive substances (TBARS) increased in the brain and liver of the fish exposed to zinc(II) for 45 days at both metal concentrations. In muscle, zinc(II) increased TBARS production at both exposure times and concentrations tested. Copper(II) exposure reduced the TBARS levels in liver at both concentrations and times tested. In brain, there was a decrease in TBARS levels only after 45 days of exposure. In muscle, this decrease was observed after 30 days of exposure at both concentrations. Although zinc and copper are required as microelements in the cells, our results showed that the sublethal concentrations of these metals can change biochemical parameters which may alter normal cellular function. These results pointed out the differential sensitivity of fish tissues to essential, but also toxic and environmentally relevant metals. The alterations of distinct biochemical parameters in fish tissues certainly contribute to the toxicity of Zn and Cu, and are of importance for an area that has been growing and has still been poorly explored in the literature.
    MeSH term(s) Animals ; Brain/drug effects ; Brain/metabolism ; Catalase/metabolism ; Copper/toxicity ; Erythrocyte Count ; Female ; Fishes/metabolism ; Hematocrit ; Hemoglobins/metabolism ; Kidney/drug effects ; Kidney/metabolism ; Liver/drug effects ; Liver/metabolism ; Male ; Muscles/drug effects ; Muscles/metabolism ; Porphobilinogen Synthase/metabolism ; Thiobarbituric Acid Reactive Substances/metabolism ; Water Pollutants, Chemical/toxicity ; Zinc/toxicity
    Chemical Substances Hemoglobins ; Thiobarbituric Acid Reactive Substances ; Water Pollutants, Chemical ; Copper (789U1901C5) ; Catalase (EC 1.11.1.6) ; Porphobilinogen Synthase (EC 4.2.1.24) ; Zinc (J41CSQ7QDS)
    Language English
    Publishing date 2007-08
    Publishing country England
    Document type Journal Article
    ZDB-ID 120089-6
    ISSN 1879-1298 ; 0045-6535 ; 0366-7111
    ISSN (online) 1879-1298
    ISSN 0045-6535 ; 0366-7111
    DOI 10.1016/j.chemosphere.2007.04.008
    Database MEDical Literature Analysis and Retrieval System OnLINE

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