LIVIVO - The Search Portal for Life Sciences

zur deutschen Oberfläche wechseln
Advanced search

Search results

Result 1 - 3 of total 3

Search options

  1. Article ; Online: Continuous positive airway pressure to avoid intubation in SARS-CoV-2 pneumonia: a two-period retrospective case-control study.

    Oranger, Mathilde / Gonzalez-Bermejo, Jésus / Dacosta-Noble, Philippine / Llontop, Claudia / Guerder, Antoine / Trosini-Desert, Valery / Faure, Morgane / Raux, Mathieu / Decavele, Maxens / Demoule, Alexandre / Morélot-Panzini, Capucine / Similowski, Thomas

    The European respiratory journal

    2020  Volume 56, Issue 2

    MeSH term(s) Betacoronavirus ; COVID-19 ; Case-Control Studies ; China ; Continuous Positive Airway Pressure ; Coronavirus ; Coronavirus Infections/epidemiology ; Humans ; Intubation, Intratracheal ; Pandemics ; Pneumonia, Viral/epidemiology ; Retrospective Studies ; SARS-CoV-2
    Keywords covid19
    Language English
    Publishing date 2020-08-13
    Publishing country England
    Document type Letter ; Comment
    ZDB-ID 639359-7
    ISSN 1399-3003 ; 0903-1936
    ISSN (online) 1399-3003
    ISSN 0903-1936
    DOI 10.1183/13993003.01692-2020
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 2322: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)
    Zs.MO 292: Show issues

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  2. Article ; Online: Positive plasma cotinine during platinum-based chemotherapy is associated with poor response rate in advanced non-small cell lung cancer patients.

    Dacosta-Noble, Philippine / Costantini, Adrien / Dumenil, Coraline / Dumoulin, Jennifer / Helly de Tauriers, Pierre / Giraud, Violaine / Labrune, Sylvie / Emile, Jean-François / Alvarez, Jean-Claude / Chinet, Thierry / Giroux Leprieur, Etienne

    PloS one

    2019  Volume 14, Issue 7, Page(s) e0219080

    Abstract: Introduction: Patients with advanced non-small cell lung cancer (NSCLC) are most of the time treated with a first-line cytotoxic chemotherapy. Tobacco use is responsible for 90% of lung cancer. The aim of this study was to evaluate the impact of smoking ...

    Abstract Introduction: Patients with advanced non-small cell lung cancer (NSCLC) are most of the time treated with a first-line cytotoxic chemotherapy. Tobacco use is responsible for 90% of lung cancer. The aim of this study was to evaluate the impact of smoking continuation during first-line chemotherapy on tumor response in advanced-stage NSCLC.
    Materials and methods: All patients with an advanced-stage NSCLC (IIIb or IV), treated with first-line platinum-based chemotherapy in our Department between June 2013 and July 2017 were included. Smoking status was assessed at inclusion by self-report, then at the tumor assessment consultation after 2 months of treatment, by both self-report and plasmatic cotinine measurement. Chemotherapy response, progression-free survival (PFS), overall survival (OS) and stage 3-4 toxicity were registered.
    Results: Ninety-seven patients were included: 8 (8%) declared to be non-smokers, 56 (58%) current smokers and 33 (34%) former smokers at diagnosis. At the first tumor evaluation, 24 (25%) self-reported as active smokers and 73 (75%) as non-smokers; overall response rate (ORR) was respectively 38% and 48% (p = 0.373). Fifty-four patients had a plasmatic cotinine evaluation at the first tumor evaluation. Seventeen patients (32%) had a positive cotinine rate (median 108ng/mL, IQR 31-236). Six patients (35%) had positive cotinine rate whereas declaring to be non-smokers at the first tumor evaluation. ORR was 18% in case of positive cotinine rate, and 57% when negative (p = 0.007). Regardless of the method for smoking status evaluation, PFS, OS and grade 3-4 toxicities were similar between smoker and non-smoker patients at the first tumor evaluation.
    Conclusion: Smoking continuation during platinum-based chemotherapy, reflected by positive plasma cotinine rate, was associated with a poor ORR.
    MeSH term(s) Adult ; Aged ; Aged, 80 and over ; Antineoplastic Agents/therapeutic use ; Biomarkers/blood ; Carcinoma, Non-Small-Cell Lung/blood ; Carcinoma, Non-Small-Cell Lung/drug therapy ; Carcinoma, Non-Small-Cell Lung/mortality ; Cotinine/blood ; Disease-Free Survival ; Female ; France/epidemiology ; Humans ; Kaplan-Meier Estimate ; Lung Neoplasms/blood ; Lung Neoplasms/drug therapy ; Lung Neoplasms/mortality ; Male ; Middle Aged ; Platinum Compounds/therapeutic use ; Prognosis ; Prospective Studies ; Retrospective Studies ; Tobacco Smoking/adverse effects ; Tobacco Smoking/blood
    Chemical Substances Antineoplastic Agents ; Biomarkers ; Platinum Compounds ; Cotinine (K5161X06LL)
    Language English
    Publishing date 2019-07-01
    Publishing country United States
    Document type Journal Article ; Observational Study
    ISSN 1932-6203
    ISSN (online) 1932-6203
    DOI 10.1371/journal.pone.0219080
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  3. Article: Continuous positive airway pressure to avoid intubation in SARS-CoV-2 pneumonia: a two-period retrospective case-control study

    Oranger, Mathilde / Gonzalez-Bermejo, Jésus / Dacosta-Noble, Philippine / Llontop, Claudia / Guerder, Antoine / Trosini-Desert, Valery / Faure, Morgane / Raux, Mathieu / Decavele, Maxens / Demoule, Alexandre / Morélot-Panzini, Capucine / Similowski, Thomas

    Eur. respir. j

    Keywords covid19
    Publisher WHO
    Document type Article
    Note WHO #Covidence: #324308
    Database COVID19

    Kategorien

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

To top