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  1. Article ; Online: Adversarial Transferred Data-Assisted Soft Sensor for Enhanced Multigrade Quality Prediction.

    Dai, Yun / Yang, Chao / Zhu, Jialiang / Liu, Yi

    ACS omega

    2023  Volume 8, Issue 22, Page(s) 19900–19911

    Abstract: Although recent transfer learning soft sensors show promising applications in multigrade chemical processes, good prediction performance mainly relies on available target domain data, which is difficult to achieve for a start-up grade. Additionally, only ...

    Abstract Although recent transfer learning soft sensors show promising applications in multigrade chemical processes, good prediction performance mainly relies on available target domain data, which is difficult to achieve for a start-up grade. Additionally, only employing a single global model is inadequate to characterize the inner relationship of process variables. A just-in-time adversarial transfer learning (JATL) soft sensing method is developed to enhance multigrade process prediction performance. The distribution discrepancies of process variables between two different operating grades are first reduced by the ATL strategy. Subsequently, by applying the just-in-time learning approach, a similar data set is selected from the transferred source data for reliable model construction. Consequently, with the JATL-based soft sensor, quality prediction of a new target grade is implemented without its own labeled data. Experimental results on two multigrade chemical processes validate that the JATL method can give rise to the improvement of model performance.
    Language English
    Publishing date 2023-05-25
    Publishing country United States
    Document type Journal Article
    ISSN 2470-1343
    ISSN (online) 2470-1343
    DOI 10.1021/acsomega.3c01832
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Editorial: Combating cancer with natural products: Non-coding RNA and RNA modification.

    Huang, Yongye / Hou, Yue / Qu, Peng / Dai, Yun

    Frontiers in pharmacology

    2023  Volume 14, Page(s) 1149777

    Language English
    Publishing date 2023-02-10
    Publishing country Switzerland
    Document type Editorial
    ZDB-ID 2587355-6
    ISSN 1663-9812
    ISSN 1663-9812
    DOI 10.3389/fphar.2023.1149777
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Editorial: Epigenetic, metabolic, and transcriptional regulation of immune cell plasticity and functions in cancer and non-cancer diseases.

    Dai, Yun / Ren, Dong / He, Yafeng / Yi, Huanfa

    Frontiers in immunology

    2023  Volume 14, Page(s) 1284124

    MeSH term(s) Humans ; Cell Plasticity ; Neoplasms/genetics ; Gene Expression Regulation ; Biochemical Phenomena ; Epigenesis, Genetic
    Language English
    Publishing date 2023-09-25
    Publishing country Switzerland
    Document type Editorial ; Research Support, Non-U.S. Gov't
    ZDB-ID 2606827-8
    ISSN 1664-3224 ; 1664-3224
    ISSN (online) 1664-3224
    ISSN 1664-3224
    DOI 10.3389/fimmu.2023.1284124
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: [Safe Utilization Effect of Passivator on Mild to Moderate Cadmium Contaminated Farmland].

    Wang, Xiao-Jing / Zhang, Dong-Ming / Cao, Yang / Lü, Jia-Long / Dai, Yun-Chao

    Huan jing ke xue= Huanjing kexue

    2024  Volume 45, Issue 2, Page(s) 1098–1106

    Abstract: In order to study the safe utilization of acid cadmium (Cd) contaminated soil, light and moderate Cd-contaminated farmland in Shangluo, Shaanxi Province was taken as the research object, and lime, biochar, and calcium magnesium phosphate fertilizer were ... ...

    Abstract In order to study the safe utilization of acid cadmium (Cd) contaminated soil, light and moderate Cd-contaminated farmland in Shangluo, Shaanxi Province was taken as the research object, and lime, biochar, and calcium magnesium phosphate fertilizer were applied. Through the wheat-maize rotation experiment, the safe utilization effect of different amounts of passivator on Cd-contaminated soil was explored, and the best ratio of passivator was selected. The results showed that: ① the soil quality could be improved to varying degrees by applying the passivator. ② After the application of amendments, the grain yield of wheat and maize increased to different degrees. ③ The lime 2 340 kg·hm
    MeSH term(s) Farms ; Cadmium/analysis ; Soil Pollutants/analysis ; Charcoal/chemistry ; Soil/chemistry ; Environmental Pollutants ; Triticum ; Oryza ; Oxides ; Calcium Compounds
    Chemical Substances Cadmium (00BH33GNGH) ; lime (C7X2M0VVNH) ; biochar ; Soil Pollutants ; Charcoal (16291-96-6) ; Soil ; Environmental Pollutants ; Oxides ; Calcium Compounds
    Language Chinese
    Publishing date 2024-03-12
    Publishing country China
    Document type English Abstract ; Journal Article
    ISSN 0250-3301
    ISSN 0250-3301
    DOI 10.13227/j.hjkx.202303151
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Influence of Helicobacter pylori Infection and Eradication on Small Intestinal Bacterial Overgrowth and Abdominal Symptoms.

    Wang, Xiaolei / Zhu, Die / Li, Siyu / Dai, Yun / Teng, Guigen / Wang, Weihong

    Digestive diseases and sciences

    2024  Volume 69, Issue 4, Page(s) 1293–1301

    Abstract: Background: The relationship between Helicobacter pylori (H. pylori) infection and small intestinal bacterial overgrowth (SIBO) has attracted attention recently.: Aims: To analyze the influence of H. pylori infection and eradication on SIBO, IMO, and ...

    Abstract Background: The relationship between Helicobacter pylori (H. pylori) infection and small intestinal bacterial overgrowth (SIBO) has attracted attention recently.
    Aims: To analyze the influence of H. pylori infection and eradication on SIBO, IMO, and abdominal symptoms.
    Methods: Patients with gastrointestinal symptoms were tested for
    Results: Of the 102 subjects, 53 were H. pylori positive. The prevalence of SIBO and IMO were higher in patients with H. pylori infection than in those without infection (49.1% vs 24.5%, P = 0.019 for SIBO; 24.5% vs 8.2%, P = 0.027 for IMO). GSRS scores were similar between H. pylori-infected and uninfected patients (2 (IQR: 1;3) vs 2 (IQR: 1;2), P = 0.211). Patients with SIBO or IMO presented higher GSRS scores than patients with both SIBO and IMO negative (2 (IQR: 2;3), 2 (IQR: 2;3) vs 2 (IQR: 1;2), P = 0.011, 0.001, respectively). For the 50 patients who successfully eradicated H. pylori, the response rates for SIBO and IMO were 66.7% and 76.9%, respectively. GSRS scores also significantly decreased (2 (IQR: 1;3) to 0 (IQR: 0;1), P < 0.001) after eradication.
    Conclusion: Helicobacter pylori infection was associated with higher prevalence of SIBO and IMO, both of which led to more pronounced abdominal symptoms. H. pylori eradication also achieved therapeutic effects on SIBO and IMO, accompanied by relief of abdominal symptoms.
    MeSH term(s) Humans ; Helicobacter Infections/drug therapy ; Helicobacter pylori ; Gastrointestinal Diseases/microbiology ; Bismuth/therapeutic use ; Lactulose/therapeutic use ; Breath Tests ; Anti-Bacterial Agents/therapeutic use ; Drug Therapy, Combination
    Chemical Substances Bismuth (U015TT5I8H) ; Lactulose (4618-18-2) ; Anti-Bacterial Agents
    Language English
    Publishing date 2024-02-15
    Publishing country United States
    Document type Journal Article
    ZDB-ID 304250-9
    ISSN 1573-2568 ; 0163-2116
    ISSN (online) 1573-2568
    ISSN 0163-2116
    DOI 10.1007/s10620-024-08279-y
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Metabolic reprogramming and interventions in endometrial carcinoma.

    Li, Jiajia / Yang, Hongmei / Zhang, Lingyi / Zhang, Songling / Dai, Yun

    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

    2023  Volume 161, Page(s) 114526

    Abstract: Cancer cells are usually featured by metabolic adaptations that facilitate their growth, invasion, and metastasis. Thus, reprogramming of intracellular energy metabolism is currently one of the hotspots in the field of cancer research. Whereas aerobic ... ...

    Abstract Cancer cells are usually featured by metabolic adaptations that facilitate their growth, invasion, and metastasis. Thus, reprogramming of intracellular energy metabolism is currently one of the hotspots in the field of cancer research. Whereas aerobic glycolysis (known as the Warburg effect) has long been considered a dominant form of energy metabolism in cancer cells, emerging evidence indicates that other metabolic forms, especially oxidative phosphorylation (OXPHOS), may play a critical role at least in some types of cancer. Of note, women with metabolic syndromes (MetS), including obesity, hyperglycemia, dyslipidemia, and hypertension, have an increased risk of developing endometrial carcinoma (EC), suggesting a close link between metabolism and EC. Interestingly, the metabolic preferences vary among EC cell types, particularly cancer stem cells and chemotherapy-resistant cells. Currently, it is commonly accepted that glycolysis is the main energy provider in EC cells, while OXPHOS is reduced or impaired. Moreover, agents specifically targeting the glycolysis and/or OXPHOS pathways can inhibit tumor cell growth and promote chemosensitization. For example, metformin and weight control not only reduce the incidence of EC but also improve the prognosis of EC patients. In this review, we comprehensively overview the current in-depth understanding of the relationship between metabolism and EC and provide up-to-date insights into the development of novel therapies targeting energy metabolism for auxiliary treatment in combination with chemotherapy for EC, especially those resistant to conventional chemotherapy.
    MeSH term(s) Humans ; Female ; Energy Metabolism ; Glycolysis ; Oxidative Phosphorylation ; Citric Acid Cycle ; Endometrial Neoplasms/drug therapy
    Language English
    Publishing date 2023-03-16
    Publishing country France
    Document type Journal Article ; Review
    ZDB-ID 392415-4
    ISSN 1950-6007 ; 0753-3322 ; 0300-0893
    ISSN (online) 1950-6007
    ISSN 0753-3322 ; 0300-0893
    DOI 10.1016/j.biopha.2023.114526
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Ocular aberration measurement with and without an aperture stop using a Shack-Hartmann wavefront sensor.

    Yang, Yanrong / Huang, Linhai / Zhao, Junlei / Gu, Naiting / Dai, Yun

    Applied optics

    2023  Volume 62, Issue 35, Page(s) 9361–9367

    Abstract: Pupil size is an important parameter since it governs the magnitude of ocular aberrations. The pupil size of a human eye has significant individual differences and varies with light level and accommodation. In order to accurately measure ocular ... ...

    Abstract Pupil size is an important parameter since it governs the magnitude of ocular aberrations. The pupil size of a human eye has significant individual differences and varies with light level and accommodation. In order to accurately measure ocular aberrations under different pupil sizes using a Shack-Hartmann wavefront sensor (SHWFS), two types of relationship matrices
    Language English
    Publishing date 2023-12-18
    Publishing country United States
    Document type Journal Article
    ISSN 1539-4522
    ISSN (online) 1539-4522
    DOI 10.1364/AO.505211
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article: Efficacy and safety of vonoprazan-amoxicillin dual therapy for

    Wang, Xiaolei / Teng, Guigen / Dong, Xinhong / Dai, Yun / Wang, Weihong

    Therapeutic advances in gastroenterology

    2023  Volume 16, Page(s) 17562848231190976

    Abstract: Background: With the increase in antibiotic resistance, the success rate of : Objectives: To compare the efficacy and safety of VA dual therapy and bismuth quadruple therapy containing amoxicillin and clarithromycin for : Design: This study was a ... ...

    Abstract Background: With the increase in antibiotic resistance, the success rate of
    Objectives: To compare the efficacy and safety of VA dual therapy and bismuth quadruple therapy containing amoxicillin and clarithromycin for
    Design: This study was a single-center, open-label, randomized controlled trial.
    Methods: Treatment-naïve
    Results: A total of 151 patients were enrolled. The intention-to-treat (ITT), modified intention-to-treat (mITT), and per-protocol (PP) eradication rates and their 95% confidence intervals (95% CIs) were 94.6% (86.0-98.3%), 98.6% (91.3-99.9%), and 98.5% (90.9-99.9%) for VA group and 87.0% (77.0-93.3%), 91.8% (82.3-96.6%), and 93% (83.7-97.4%) for RBAC group. The eradication rate of the VA group was noninferior to the RBAC group in ITT, mITT, and PP analyses (
    Conclusion: The efficacy of VA dual therapy is noninferior to RBAC in
    Registration: This study was registered at the Chinese Clinical Trial Registry (ChiCTR2100052550) on 30 October 2021.
    Language English
    Publishing date 2023-08-30
    Publishing country England
    Document type Journal Article
    ZDB-ID 2440710-0
    ISSN 1756-2848 ; 1756-283X
    ISSN (online) 1756-2848
    ISSN 1756-283X
    DOI 10.1177/17562848231190976
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article: Empirical

    Li, Meng / Wang, Xiaolei / Meng, Wenting / Dai, Yun / Wang, Weihong

    Therapeutic advances in gastroenterology

    2023  Volume 16, Page(s) 17562848231196357

    Abstract: Background: The eradication rate of : Objectives: The purpose of our study was to evaluate whether tailored therapy based on genotypic resistance is superior to empirical therapy for : Design: A systematic review and meta-analysis of randomized ... ...

    Abstract Background: The eradication rate of
    Objectives: The purpose of our study was to evaluate whether tailored therapy based on genotypic resistance is superior to empirical therapy for
    Design: A systematic review and meta-analysis of randomized controlled trials (RCTs) comparing tailored therapy based on genotypic resistance with empirical therapy was performed.
    Sources and methods: We retrieved relevant studies from PubMed, Embase, and the Cochrane Library. The primary outcome was
    Results: A total of 12 qualified RCTs containing 3940 patients were identified in our systematic review and meta-analysis. The pooled eradication rates of tailored therapy based on the detection of genotypic resistance were consistently higher than those in the empirical treatment group, with no statistical significance. In triple therapy, the eradication rate was significantly higher in the tailored group than in the empirical group by intention-to-treat analysis (ITT) and per-protocol analysis (PP) analysis (
    Conclusion: In conclusion, tailored therapy based on molecular methods may offer better efficacy than empirical triple therapy, but it may not be superior to empirical quadruple therapy in eradicating
    Registration prospero: CRD42023408688.
    Language English
    Publishing date 2023-08-31
    Publishing country England
    Document type Journal Article
    ZDB-ID 2440710-0
    ISSN 1756-2848 ; 1756-283X
    ISSN (online) 1756-2848
    ISSN 1756-283X
    DOI 10.1177/17562848231196357
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article: Treatment of Liver Fibrosis: A 20-Year Bibliometric and Knowledge-Map Analysis.

    Dai, Yun-Kai / Zhao, Zhi-Min / Liu, Chenghai

    Frontiers in pharmacology

    2022  Volume 13, Page(s) 942841

    Abstract: Objectives: ...

    Abstract Objectives:
    Language English
    Publishing date 2022-07-12
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2587355-6
    ISSN 1663-9812
    ISSN 1663-9812
    DOI 10.3389/fphar.2022.942841
    Database MEDical Literature Analysis and Retrieval System OnLINE

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