Article ; Online: Chemosensory receptor specificity and regulation.
2015 Volume 38, Page(s) 331–349
Abstract: The senses provide a means by which data on the physical and chemical properties of the environment may be collected and meaningfully interpreted. Sensation begins at the periphery, where a multitude of different sensory cell types are activated by ... ...
Abstract | The senses provide a means by which data on the physical and chemical properties of the environment may be collected and meaningfully interpreted. Sensation begins at the periphery, where a multitude of different sensory cell types are activated by environmental stimuli as different as photons and odorant molecules. Stimulus sensitivity is due to expression of different cell surface sensory receptors, and therefore the receptive field of each sense is defined by the aggregate of expressed receptors in each sensory tissue. Here, we review current understanding on patterns of expression and modes of regulation of sensory receptors. |
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MeSH term(s) | Animals ; Receptors, G-Protein-Coupled/genetics ; Receptors, G-Protein-Coupled/physiology ; Receptors, Odorant/genetics ; Receptors, Odorant/physiology ; Sensory Receptor Cells/physiology ; Vomeronasal Organ/physiology |
Chemical Substances | Receptors, G-Protein-Coupled ; Receptors, Odorant ; taste receptors, type 1 ; taste receptors, type 2 |
Language | English |
Publishing date | 2015-07-08 |
Publishing country | United States |
Document type | Journal Article ; Research Support, N.I.H., Extramural ; Review |
ZDB-ID | 282459-0 |
ISSN | 1545-4126 ; 0147-006X |
ISSN (online) | 1545-4126 |
ISSN | 0147-006X |
DOI | 10.1146/annurev-neuro-071714-034145 |
Database | MEDical Literature Analysis and Retrieval System OnLINE |
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