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  1. Article ; Online: [No title information]

    Gramkow, Mathias Holsey / Damsgaard, Line / McWilliam, Oskar / Roos, Peter

    Ugeskrift for laeger

    2023  Volume 185, Issue 50

    Abstract: Introduction Christmas-themed scientific articles are becoming increasingly popular and may represent a shortcut to scientific demise due to their demand for time better spent on "serious" research. We aimed to investigate whether authorship on Christmas- ...

    Title translation Christmas article: Christmas lasts a long time, but do Christmas article writers? A bibliometric case-control study.
    Abstract Introduction Christmas-themed scientific articles are becoming increasingly popular and may represent a shortcut to scientific demise due to their demand for time better spent on "serious" research. We aimed to investigate whether authorship on Christmas-themed medical articles could damage the scientific careers of authors. We hypothesized that Christmas-authorships had a negative impact on core bibliometric outcomes such as publication rates. Methods We extracted demographic and bibliometric data on first- and last authors of medical papers written for the Christmas edition of Journal of The Danish Medical Association through the years 2010-2012. These cases were compared with controls representing authors of original "serious" research papers written in the same years. We performed a negative binomial regression with the number of publications ten years after the index date (defined as the publication year of Christmas/"serious" article) as the outcome and adjusted models for sex and age. Results We found that first authors of Christmas-themed papers had a publication rate ratio (PRR) of 3.8 (95% confidence interval (CI): 1.4-12.4) in unadjusted analysis and last authors had a PRR of 0.6 (95% CI: 0.2-1.6). The associations weakened and were statistically insignificant in adjusted analyses. Conclusion Our results indicate that first authors publish more in the years following the publication of a Christmas article, although the association may be entirely driven by sex and age. Causality remains uncertain and further studies (such as RCTs) which randomize authors to produce Christmas-themed (preferably in a Santa's workshop setting) or serious articles are needed. Funding. None. Trial registration. None.
    MeSH term(s) Humans ; Case-Control Studies ; Bibliometrics ; Authorship
    Language Danish
    Publishing date 2023-12-11
    Publishing country Denmark
    Document type English Abstract ; Journal Article
    ZDB-ID 124102-3
    ISSN 1603-6824 ; 0041-5782
    ISSN (online) 1603-6824
    ISSN 0041-5782
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Healthcare utilization prior to a diagnosis of young-onset Alzheimer's disease: a nationwide nested case-control study.

    Damsgaard, Line / Janbek, Janet / Laursen, Thomas Munk / Waldemar, Gunhild / Jensen-Dahm, Christina

    Journal of neurology

    2023  Volume 270, Issue 12, Page(s) 6093–6102

    Abstract: Objective: Our aim was to identify changes in healthcare utilization prior to a young-onset Alzheimer's disease diagnosis.: Methods: In a retrospective incidence density matched nested case-control study using national health registers, we examined ... ...

    Abstract Objective: Our aim was to identify changes in healthcare utilization prior to a young-onset Alzheimer's disease diagnosis.
    Methods: In a retrospective incidence density matched nested case-control study using national health registers, we examined healthcare utilization for those diagnosed with young-onset Alzheimer's disease in Danish memory clinics during 2016-2018 compared with age- and sex-matched controls. Negative binomial regression analysis produced contact rate ratios.
    Results: The study included 1082 young-onset Alzheimer's disease patients and 3246 controls. In the year preceding diagnosis, we found increased contact rate ratios for all types of contacts except physiotherapy. Contact rate ratios for contacts with a general practitioner were significantly increased also > 1-5 and > 5-10 years before diagnosis. The highest contact rate ratios were for psychiatric emergency contacts (8.69, 95% CI 4.29-17.62) ≤ 1 year before diagnosis.
    Interpretation: Results demonstrate that young-onset Alzheimer's disease patients have increased healthcare utilization from 5 to 10 years prior to diagnosis. Awareness of specific alterations in health-seeking behaviour may help healthcare professionals provide timely diagnoses.
    MeSH term(s) Humans ; Alzheimer Disease/diagnosis ; Alzheimer Disease/epidemiology ; Alzheimer Disease/therapy ; Case-Control Studies ; Retrospective Studies ; Patient Acceptance of Health Care
    Language English
    Publishing date 2023-09-05
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 187050-6
    ISSN 1432-1459 ; 0340-5354 ; 0012-1037 ; 0939-1517 ; 1619-800X
    ISSN (online) 1432-1459
    ISSN 0340-5354 ; 0012-1037 ; 0939-1517 ; 1619-800X
    DOI 10.1007/s00415-023-11974-x
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Mapping morbidity 10 years prior to a diagnosis of young onset Alzheimer's disease.

    Damsgaard, Line / Janbek, Janet / Laursen, Thomas M / Høgh, Peter / Vestergaard, Karsten / Gottrup, Hanne / Jensen-Dahm, Christina / Waldemar, Gunhild

    Alzheimer's & dementia : the journal of the Alzheimer's Association

    2024  Volume 20, Issue 4, Page(s) 2373–2383

    Abstract: Introduction: Early symptoms in young onset Alzheimer's disease (YOAD) may be misinterpreted, causing delayed diagnosis. This population-based study aimed to map morbidity prior to YOAD diagnosis.: Methods: In a register-based incidence density ... ...

    Abstract Introduction: Early symptoms in young onset Alzheimer's disease (YOAD) may be misinterpreted, causing delayed diagnosis. This population-based study aimed to map morbidity prior to YOAD diagnosis.
    Methods: In a register-based incidence density matched nested case-control study, we examined hospital-diagnosed morbidity for people diagnosed with YOAD in Danish memory clinics during 2016-2020 compared to controls in a 10-year period. Conditional logistic regression produced incidence rate ratios (IRRs).
    Results: The study included 1745 cases and 5235 controls. YOAD patients had a higher morbidity burden in the year immediately before dementia diagnosis, for certain disorders up to 10 years before. This was especially evident for psychiatric morbidity with the highest increased IRRs throughout the entire period and IRR 1.43 (95% confidence interval 1.14-1.79) in the 5-10-years before dementia diagnosis.
    Discussion: YOAD patients display a different pattern of morbidity up to 10 years prior to diagnosis. Awareness of specific alterations in morbidity may improve efforts toward a timely diagnosis.
    Highlights: Retrospective, nested case-control study of young onset Alzheimer's disease (YOAD). YOAD cases had a higher morbidity burden than controls. YOAD cases had a higher psychiatric morbidity burden up to 10 years before diagnosis. Altered morbidity patterns could serve as an early warning sign of YOAD.
    MeSH term(s) Humans ; Alzheimer Disease/diagnosis ; Alzheimer Disease/epidemiology ; Alzheimer Disease/psychology ; Retrospective Studies ; Case-Control Studies ; Morbidity
    Language English
    Publishing date 2024-01-31
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2211627-8
    ISSN 1552-5279 ; 1552-5260
    ISSN (online) 1552-5279
    ISSN 1552-5260
    DOI 10.1002/alz.13681
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Tweens - a new target group for the ice cream industry?

    Damsgaard, Line

    European dairy magazine

    2015  Volume 27, Issue 2, Page(s) 6–8

    Language German ; English
    Document type Article
    ZDB-ID 1018750-9
    ISSN 0936-6318
    Database Current Contents Nutrition, Environment, Agriculture

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  5. Article ; Online: Hospital-diagnosed sleep disorders and incident dementia: a nationwide observational cohort study.

    Damsgaard, Line / Janbek, Janet / Laursen, Thomas Munk / Erlangsen, Annette / Spira, Adam P / Waldemar, Gunhild

    European journal of neurology

    2022  Volume 29, Issue 12, Page(s) 3528–3536

    Abstract: Background and purpose: Several smaller, community-based studies have suggested a link between sleep disorders and dementia with a focus on sleep as a modifiable risk factor for dementia. Studies on neurodegenerative diseases are prone to reverse ... ...

    Abstract Background and purpose: Several smaller, community-based studies have suggested a link between sleep disorders and dementia with a focus on sleep as a modifiable risk factor for dementia. Studies on neurodegenerative diseases are prone to reverse causation, and few studies have examined the association with long follow-up time. Our aim was to explore the possible association between sleep disorders and late-onset dementia in an entire population.
    Methods: In a nationwide cohort with 40-year follow-up, associations between hospital-based sleep disorder diagnoses and late-onset dementia were assessed. Incidence rate ratios (IRR) were calculated using Poisson regression.
    Results: The cohort consisted of 1,491,276 people. Those with any sleep disorder had a 17% higher risk of dementia (IRR 1.17, 95% confidence interval [CI] 1.11-1.24) compared to people with no sleep disorder, adjusted for age, sex, calendar year, highest attained educational level at age 50, and somatic and psychiatric comorbidity. The risk of dementia was significantly increased 0-5 years after sleep disorder diagnosis (IRR 1.35, 95% CI 1.25-1.47), whilst the association after 5 years or more was non-significant (1.05, 95% CI 0.97-1.13).
    Conclusions: Our findings show an increased short-term risk of dementia following a hospital-based sleep disorder diagnosis, whilst weaker evidence of a long-term risk was found. This could potentially point towards sleep disorders as an early symptom of dementia. Further research is needed to distinguish sleep disorders as an early symptom of dementia, a risk factor, or both.
    MeSH term(s) Humans ; Middle Aged ; Sleep Wake Disorders/complications ; Cohort Studies ; Incidence ; Risk Factors ; Hospitals ; Dementia/epidemiology
    Language English
    Publishing date 2022-08-18
    Publishing country England
    Document type Observational Study ; Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 1280785-0
    ISSN 1468-1331 ; 1351-5101 ; 1471-0552
    ISSN (online) 1468-1331
    ISSN 1351-5101 ; 1471-0552
    DOI 10.1111/ene.15517
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: Use of glycosylated haemoglobin as diagnostic tool in Greenland: prevalence of diagnosed diabetes mellitus.

    Damsgaard, Line / Pedersen, Michael Lynge

    Diabetology & metabolic syndrome

    2013  Volume 5, Issue 1, Page(s) 59

    Abstract: Background: The prevalence of undiagnosed diabetes mellitus (DM) in Greenland has been reported very high with only 30% of cases diagnosed. In 2010, glycosylated hemoglobin (A1C) was introduced as a diagnostic tool in Greenland. However, the current use ...

    Abstract Background: The prevalence of undiagnosed diabetes mellitus (DM) in Greenland has been reported very high with only 30% of cases diagnosed. In 2010, glycosylated hemoglobin (A1C) was introduced as a diagnostic tool in Greenland. However, the current use of A1c is unknown as well as the current prevalence of diagnosed DM.The aim of this study was firstly to estimate the use of A1C as diagnostic tool within the first 27 months after introducing the method and secondly to estimate the age and gender specific prevalence of diagnosed DM in Greenland in 2012.
    Methods: This study was perfomed as a cross-sectional register study using data from electronic medical records (EMR). To analyse the use of A1C as diagnostic tool:A sample amongst all Greenlanders at or above age 35 old was used to determine the number of individuals screened with A1C within a 27 month period, excluding those already known to have DM.To estimate the prevalence of diagnosted DM: Patients with DM were identified electronically using a statistic module run on data in the EMR. Age and gender specific prevalence was estimated using the Greenlandic population as of 1 January 2012 as the background population.
    Results: The test sample resulted in a study group of 1008 individuals from which 2.3% (23) were excluded because they were already known to have DM. Among the remaining 985, 13.6% were tested with A1C at least once during the 27 months of observation. DM was diagnosed in 7.5% (10) of the tested persons and in 1.0% of the whole group.Regarding prevalence, a total of 920 patients with diagnosed DM were identified. The total prevalence among adults aged 20-79 years old was 2.20% (95% CI: 2.05-2.34) with no significant difference between genders.
    Conclusion: Testing for DM using A1C as diagnostic tool is used in Greenland. The prevalence of diagnosed DM in Greenland remains low although increasing. Undiagnosed DM may still be an important issue in Greenland.
    Language English
    Publishing date 2013-10-09
    Publishing country England
    Document type Journal Article
    ZDB-ID 2518786-7
    ISSN 1758-5996
    ISSN 1758-5996
    DOI 10.1186/1758-5996-5-59
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Use of antibiotics at the emergency department

    Damsgaard Line / Oestergaard Asta

    Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine, Vol 18, Iss Suppl 1, p P

    2010  Volume 39

    Keywords Medical emergencies. Critical care. Intensive care. First aid ; RC86-88.9 ; Internal medicine ; RC31-1245 ; Medicine ; R ; DOAJ:Internal medicine ; DOAJ:Medicine (General) ; DOAJ:Health Sciences
    Language English
    Publishing date 2010-09-01T00:00:00Z
    Publisher BioMed Central
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  8. Article ; Online: Efficient guidelines support professionalism

    Damsgaard Line / Mølbak Anne Grethe

    Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine, Vol 18, Iss Suppl 1, p P

    2010  Volume 11

    Keywords Medical emergencies. Critical care. Intensive care. First aid ; RC86-88.9 ; Internal medicine ; RC31-1245 ; Medicine ; R ; DOAJ:Internal medicine ; DOAJ:Medicine (General) ; DOAJ:Health Sciences
    Language English
    Publishing date 2010-09-01T00:00:00Z
    Publisher BioMed Central
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  9. Article ; Online: Wernickes encefalopati hos patienter med alkoholabstinenssymptomer.

    Damsgaard, Line / Ulrichsen, Jakob / Nielsen, Mogens Kai

    Ugeskrift for laeger

    2010  Volume 172, Issue 28, Page(s) 2054–2058

    Abstract: Introduction: Wernicke's encephalopathy (WE) is caused by lack of thiamin. In Denmark, WE most often occurs in alcoholics. In the present study, we wanted to investigate the frequency of WE in patients hospitalized for treatment of alcohol withdrawal ... ...

    Title translation Wernicke's encephalopathy in patients with alcohol withdrawal symptoms.
    Abstract Introduction: Wernicke's encephalopathy (WE) is caused by lack of thiamin. In Denmark, WE most often occurs in alcoholics. In the present study, we wanted to investigate the frequency of WE in patients hospitalized for treatment of alcohol withdrawal symptoms in a psychiatric emergency ward.
    Material and methods: Prospective registration of symptoms and treatment regimen in all patients admitted for alcohol withdrawal treatment in the period 22.02.2007-31.08.2008.
    Results: Symptoms of WE occurred in 52 of a total of 497 patients (11%). Ataxia of gait was the predominant symptom, succeeded by cognitive impairment, whereas ocular palsy was unusual. Patients with WE were on average administered approximately 50% more phenobarbital than patients without symptoms of WE (p < 0.01), probably reflecting a more severe withdrawal reaction. In 21 of the 52 patients with WE (41%) the preceding period of alcohol intake was shorter than 14 days.
    Discussion: WE is a frequently occurring condition among patients treated for alcohol withdrawal symptoms in psychiatric wards. A possible pathogenetic factor is the alcohol withdrawal reaction, as cerebral hyperactivity may lead to increased thiamin consumption and thus depletion of the depots. To avoid insufficient treatment, routine administration of large doses of intravenous thiamine to all patients admitted with alcohol withdrawal symptoms should be considered.
    MeSH term(s) Adult ; Ethanol/adverse effects ; Female ; Humans ; Male ; Middle Aged ; Prospective Studies ; Substance Withdrawal Syndrome/complications ; Substance Withdrawal Syndrome/drug therapy ; Thiamine/administration & dosage ; Vitamin B Complex/administration & dosage ; Wernicke Encephalopathy/diagnosis ; Wernicke Encephalopathy/etiology ; Wernicke Encephalopathy/prevention & control
    Chemical Substances Vitamin B Complex (12001-76-2) ; Ethanol (3K9958V90M) ; Thiamine (X66NSO3N35)
    Language Danish
    Publishing date 2010-07-12
    Publishing country Denmark
    Document type English Abstract ; Journal Article
    ZDB-ID 124102-3
    ISSN 1603-6824 ; 0041-5782
    ISSN (online) 1603-6824
    ISSN 0041-5782
    Database MEDical Literature Analysis and Retrieval System OnLINE

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