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Article ; Online: How to Achieve Carbon Neutrality in Cities? Evidence from China’s Low-Carbon Cities Development

Huaxing Wang / Chuan Chen / Zhiqiao Xiong / Dandan Li

International Journal of Environmental Research and Public Health, Vol 20, Iss 2121, p

2023 Volume 2121

Abstract: Low-carbon city pilots (LCCP) is a key policy for realizing emission peak and carbon neutrality in China, using China’s samples from 280 towns from 2006 to 2016. The article utilizes PSM-DID, mediated effects, and moderating effects approach for ... ...

Abstract	Low-carbon city pilots (LCCP) is a key policy for realizing emission peak and carbon neutrality in China, using China’s samples from 280 towns from 2006 to 2016. The article utilizes PSM-DID, mediated effects, and moderating effects approach for validating a CO 2 reduction effect, mechanisms, and synergistic elements of LCCP. The regression outcomes suggest that (1) LCCP significantly decreases CO 2 emissions levels and average annual carbon emissions in LCCP fall by 2.6 percent. (2) LCCP focus on reducing carbon emissions by increasing R&D investment, the efficiency of energy, and decreasing the high CO 2 emissions industry. Among them, the reduction of the high carbon emission industry is mainly FDI, while the reduction of local industry is not obvious. (3) LCCP’s carbon reduction effects suggest a reversed U-shape relationship with city size. Digitalization and marketization of LCCP are crucial to the carbon reduction effect. Carbon reduction and pollution reduction have a strong synergistic effect.
Keywords	LLCP ; carbon emission ; carbon neutral mechanisms ; synergistic effect ; PSM-DID ; Medicine ; R
Subject code	670
Language	English
Publishing date	2023-01-01T00:00:00Z
Publisher	MDPI AG
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Effects of Temperature and Salt Stress on the Expression of delta-12 Fatty Acid Desaturase Genes and Fatty Acid Compositions in Safflower

Dandan Li / Kaijie Li / Guangchong Zhou / Songtao He

International Journal of Molecular Sciences, Vol 24, Iss 2765, p

2023 Volume 2765

Abstract: The regulation of microsomal (e.g., FAD2) and plastidial (e.g., FAD6) oleate desaturases by cold, heat and salt stress were investigated. Gene expression levels and fatty acid compositions were determined in the roots, stems and leaves of safflower ... ...

Abstract	The regulation of microsomal (e.g., FAD2) and plastidial (e.g., FAD6) oleate desaturases by cold, heat and salt stress were investigated. Gene expression levels and fatty acid compositions were determined in the roots, stems and leaves of safflower following stress treatments. A safflower plastidial oleate desaturase gene, CtFAD6 , was cloned, and oleic acid desaturation was confirmed in Synechococcus sp. strain PCC7942. The results showed that temperature regulated oleate desaturation at the transcriptional level, and this regulation pattern was tissue-specific. CtFAD2-1 , CtFAD2-2 and CtFAD6 were significantly induced under cold and heat stress in young leaves, and CtFAD2-2 and CtFAD6 were slightly induced in young stems. In contrast, CtFAD2-1 , CtFAD2-11 and CtFAD2-10 were sensitive to salt stress in all safflower tissues (roots, stem and leaves). CtFAD6 was insensitive to salt and was slightly induced in leaves only.
Keywords	Carthamus tinctorius L ; Asteraceae ; temperature stress ; salt stress ; Δ 12 fatty acid desaturase ; Biology (General) ; QH301-705.5 ; Chemistry ; QD1-999
Language	English
Publishing date	2023-02-01T00:00:00Z
Publisher	MDPI AG
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Two-Stage Robust Lossless DWI Watermarking Based on Transformer Networks in the Wavelet Domain

Zhangyu Liu / Zhi Li / Long Zheng / Dandan Li

Applied Sciences, Vol 13, Iss 6886, p

2023 Volume 6886

Abstract: For copyright protection of diffusion-weighted imaging (DWI) images, traditional robust watermarking techniques result in irreversible distortions, while reversible watermarking methods exhibit poor robustness. We propose a two-stage lossless ... ...

Abstract	For copyright protection of diffusion-weighted imaging (DWI) images, traditional robust watermarking techniques result in irreversible distortions, while reversible watermarking methods exhibit poor robustness. We propose a two-stage lossless watermarking algorithm based on a Transformer network to solve this problem. The first stage of the algorithm is to train the robust watermarking network, embed the watermark into the cover image in the wavelet domain, and design the frequency information enhancement module to improve the reconstruction quality. In the second stage, based on the pre-trained robust watermarking network, the difference image between the watermarked image and the cover image is reversibly embedded into the watermarked image as the compensation information to losslessly recover the cover image. The difference image is compressed using DCT and Huffman coding to reduce the compensation information. Finally, the watermark extraction network is trained on the second embedding result to avoid weakening the robustness of the first stage caused by the reversible embedding. The experimental results demonstrate that the PSNR of the watermarked image reaches 60.18 dB. Under various types of image attacks, the watermark extraction BER is below 0.003, indicating excellent robustness. The cover image can be recovered losslessly under no attack.
Keywords	robust lossless watermark ; diffusion-weighted imaging ; deep learning ; Transformer ; discrete wavelet transform ; Technology ; T ; Engineering (General). Civil engineering (General) ; TA1-2040 ; Biology (General) ; QH301-705.5 ; Physics ; QC1-999 ; Chemistry ; QD1-999
Subject code	510
Language	English
Publishing date	2023-06-01T00:00:00Z
Publisher	MDPI AG
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: 18F-FDG PET/CT features of Meigs syndrome induced by ovarian sex cord stromal tumors

Xianwen Hu / Wenxin Li / Xiaotian Li / Dandan Li / Jiong Cai / Pan Wang

Scientific Reports, Vol 14, Iss 1, Pp 1-

a retrospective clinical study

2024 Volume 8

Abstract: Abstract The objective of this study was retrospectively to analyze the clinical characteristics and 18F-FDG PET/CT findings in Meigs syndrome (MS) patients. A total of 21 patients with MS induced by ovarian stromal tumors and 69 patients with pseudo-MS ... ...

Abstract	Abstract The objective of this study was retrospectively to analyze the clinical characteristics and 18F-FDG PET/CT findings in Meigs syndrome (MS) patients. A total of 21 patients with MS induced by ovarian stromal tumors and 69 patients with pseudo-MS caused by ovarian cancer (OC-PMS) were subjected to evaluation using 18F-FDG PET/CT. Visual and semi-quantitative methods were employed to analyze the PET/CT findings. Visual analysis included recording whether the density of the primary tumor was uniform, whether there were cystic changes and calcifications, and the location of serous fluid accumulation. Semi-quantitative analysis involved the measurement of the tumor size, SUVmax, and SUVmean. No significant difference was observed in the size and density of primary tumors between the MS group and the OC-PMS group. However, the SUVmax and SUVmean of tumors in the MS group were found to be significantly lower than those in the OC-PMS group. The amount of serous cavity effusion caused by ovarian sex cord stromal tumors was found to be unrelated to the size of the tumor, SUVmax, and SUVmean but was positively correlated with the level of Ca125. MS patients have both benign ovarian tumors and ascites and/or pleural effusion, which may be accompanied by elevated Ca125 levels. This should be considered as one of the differential diagnoses for ovarian cancer. Understanding the PET/CT features of MS can facilitate the attainment of an accurate diagnosis before surgery.
Keywords	Medicine ; R ; Science ; Q
Subject code	616
Language	English
Publishing date	2024-01-01T00:00:00Z
Publisher	Nature Portfolio
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Research progress of microRNAs suppressing tumorigenesis through Hippo signaling

CHA Na, HAO Dandan, LI Tianzhu

Jichu yixue yu linchuang, Vol 43, Iss 12, Pp 1871-

2023 Volume 1875

Abstract: The aberrant activation of yes-associated protein (YAP) and transcriptional coactivator with PDZ-binding motif (TAZ), downstream effectors of the Hippo signaling pathway, has been implicated in hepatocellular carcinoma(HCC). The microRNAs (miRNAs) works ... ...

Abstract	The aberrant activation of yes-associated protein (YAP) and transcriptional coactivator with PDZ-binding motif (TAZ), downstream effectors of the Hippo signaling pathway, has been implicated in hepatocellular carcinoma(HCC). The microRNAs (miRNAs) works as a tumor suppressors that influence the proliferation, migration and apoptosis of tumor cells by modulating Hippo-YAP/TAZ signaling during hepatic tumorigenesis. Exploring the role of miRNAs in regulating Hippo YAP/TAZ pathway in HCC can provide new ideas for the diagnosis and treatment of HCC.
Keywords	hepatocellular carcinoma\|hippo pathway\|micrornas\|molecular mechanism ; Medicine ; R
Language	Chinese
Publishing date	2023-12-01T00:00:00Z
Publisher	Institute of Basic Medical Sciences and Peking Union Medical College Hospital, Chinese Academy of Medical Sciences / Peking Union Medical College.
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: The effect of low-carbon pilot policy on low-carbon technological innovation in China

Hongwei Yu / Fei Peng / Taiping Yuan / Dandan Li / Daqian Shi

Journal of Innovation & Knowledge, Vol 8, Iss 3, Pp 100392- (2023)

Reexamining the porter hypothesis using difference-in-difference-in-differences strategy

2023

Abstract: The Porter hypothesis predicts that the win-win goals of environmental improvement and economic performance can be achieved though technological innovation, but it remains to be tested in elaborated ways. Explicitly identifying the role of environmental ... ...

Abstract	The Porter hypothesis predicts that the win-win goals of environmental improvement and economic performance can be achieved though technological innovation, but it remains to be tested in elaborated ways. Explicitly identifying the role of environmental regulation and finely clarifying the scope of technological innovation have become two important prerequisites for accurately testing the “Porter hypothesis”. Taking China's Low-carbon Pilot Policy as a quasi-natural experiment, this paper constructs a difference-in-difference-in-differences (DDD) strategy to identify the environmental regulation, and selects the low-carbon technological innovation which may be more dependent on Low-carbon Pilot Policy as the explanatory variable, to reexamine the “Porter hypothesis” in China. Based on the data of listed companies in China from 2007 to 2016, this paper conducts substantial empirical studies on effect estimation, robustness test and heterogeneity analysis. The results show that the Low-carbon Pilot Policy significantly promotes the low-carbon technological innovation of enterprises in high-carbon emission industries in pilot cities. The robustness test also verifies the reliability of those results which confirms the validity of “Porter hypothesis”. However, the heterogeneity analysis finds that the testing results of “Porter hypothesis” may vary depending on firms’ characteristics. The Low-carbon Pilot Policy has a positive and significant effect on the enterprises in eastern regions or in the cities with higher R&D investment, it can also promote non-state-owned enterprises’ innovation significantly. This paper may contribute to understand more about “Porter hypothesis” in China and offer strategies for more accurately testing on “Potter hypothesis”.
Keywords	O33 Q48 ; History of scholarship and learning. The humanities ; AZ20-999 ; Social sciences (General) ; H1-99
Subject code	338
Language	English
Publishing date	2023-07-01T00:00:00Z
Publisher	Elsevier
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Metalloprotein-Specific or Critical Amino Acid Residues

Dandan Li / Tengbing He / Muhammad Saleem / Guandi He

International Journal of Molecular Sciences, Vol 23, Iss 1734, p

Perspectives on Plant-Precise Detoxification and Recognition Mechanisms under Cadmium Stress

2022 Volume 1734

Abstract: Cadmium (Cd) pollution in cultivated land is caused by irresistible geological factors and human activities; intense diffusion and migration have seriously affected the safety of food crops. Plants have evolved mechanisms to control excessive influx of ... ...

Abstract	Cadmium (Cd) pollution in cultivated land is caused by irresistible geological factors and human activities; intense diffusion and migration have seriously affected the safety of food crops. Plants have evolved mechanisms to control excessive influx of Cd in the environment, such as directional transport, chelation and detoxification. This is done by some specific metalloproteins, whose key amino acid motifs have been investigated by scientists one by one. The application of powerful cell biology, crystal structure science, and molecular probe targeted labeling technology has identified a series of protein families involved in the influx, transport and detoxification of the heavy metal Cd. This review summarizes them as influx proteins (NRAMP, ZIP), chelating proteins (MT, PDF), vacuolar proteins (CAX, ABCC, MTP), long-distance transport proteins (OPT, HMA) and efflux proteins (PCR, ABCG). We selected representative proteins from each family, and compared their amino acid sequence, motif structure, subcellular location, tissue specific distribution and other characteristics of differences and common points, so as to summarize the key residues of the Cd binding target. Then, we explain its special mechanism of action from the molecular structure. In conclusion, this review is expected to provide a reference for the exploration of key amino acid targets of Cd, and lay a foundation for the intelligent design and breeding of crops with high/low Cd accumulation.
Keywords	Cd transport and detoxification ; H/DXXXD ; cysteine-related residues ; functional protein ; Biology (General) ; QH301-705.5 ; Chemistry ; QD1-999
Subject code	580
Language	English
Publishing date	2022-02-01T00:00:00Z
Publisher	MDPI AG
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Construction of Neonatal PICC Nursing Quality Evaluation System

Shi Xiaoli / Hao Weiyan / Dandan Li

Applied Bionics and Biomechanics, Vol

2022 Volume 2022

Abstract: Objective. In order to improve the quality of neonatal care, this study analyzed the construction of PICC and scientifically evaluated the quality of PICC. Methods. A total of 100 neonatal patients admitted to the Pediatric Medical Intensive Care Unit of ...

Abstract	Objective. In order to improve the quality of neonatal care, this study analyzed the construction of PICC and scientifically evaluated the quality of PICC. Methods. A total of 100 neonatal patients admitted to the Pediatric Medical Intensive Care Unit of the People’s Hospital in Laizhou City of Shandong Province between January 2015 and December 2018 were selected for nursing intervention. They were randomly divided into 50 cases in the observation group and 50 cases in the reference group. In the observation group, 50 were neonatal patients who received and completed PICC catheterization care, and in the reference group, 50 were neonatal patients with traditional conventional puncture care, PICC nursing quality evaluation index system, and nursing quality standard were applied, and questionnaire survey and patient satisfaction survey were conducted in the treatment. The two groups were compared for the success rate of one puncture, catheter detachment, treatment of local bleeding, incidence of nursing risk during other treatment, and other related nursing quality results. Results. The incidence of related medical and nursing risks in neonatal patients such as one-time puncture success rate, catheter detachment during treatment, and local bleeding was significantly lower than those in neonatal patients receiving conventional nursing methods. The incidence of nursing risk events during puncture was effectively reduced. It is shown in the comparison of adverse events in neonatal pediatric nursing in the fourth quarter of 2017 and 2018. In 2018, the proportion of adverse events in neonatal nursing is decreasing, the quality index of nursing is improving, and the satisfaction of patients’ families and relevant personnel in treatment is increasing. Conclusion. The construction and application of neonatal PICC nursing quality evaluation system can improve the success rate of one-time puncture, reduce the pain of newborns, improve the nursing quality evaluation system, scientifically and reasonably provide effective ...
Keywords	Biotechnology ; TP248.13-248.65 ; Biology (General) ; QH301-705.5
Language	English
Publishing date	2022-01-01T00:00:00Z
Publisher	Hindawi Limited
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Effects of Neonatal Feeding Patterns on Infant Health

Shi Xiaoli / Hao Weiyan / Dandan Li

Applied Bionics and Biomechanics, Vol

2022 Volume 2022

Abstract: Objective. Early and reasonable feeding mode can not only ensure the good nutritional condition of infants but also enhance the infant immunity and resistance, which has a certain role in promoting health and preventing the occurrence of chronic diseases ...

Abstract	Objective. Early and reasonable feeding mode can not only ensure the good nutritional condition of infants but also enhance the infant immunity and resistance, which has a certain role in promoting health and preventing the occurrence of chronic diseases in adulthood. In this study, the effect of neonatal feeding methods on the infant body, the influence of early feeding on the growth rate, and development of infants aged 0-3. Method. From January 2016 to June 2019, a total of 600 infants who have been systematically managed in our hospital since birth were selected. All newborns were 37-40 weeks old, weighing 2350-4100 g, without congenital diseases. They were grouped according to feeding methods. 194 infants were exclusively breastfed, 32.3%; 207 people were artificially fed, 34.5%; 199 people were mixed fed, 33.2%. The Kaup index method was used to judge the nutritional status. Developmental Screening Test for ages 0 to 6 (DST) and Bailey Infant Development Scale (BIDS) were used to rate the intellectual and behavioral development of infants and children. According to the growth and development reference standard of 0 ~ 4-year-old children recommended by who in 2006, the age weight standard deviation score (WAZ), age length (height) standard deviation score (HAZ), and body (long) height-weight standard deviation score (WHZ) were performed, and the statistical analysis was performed with SPSS24.0 software. The height, weight, intelligence, and motor development of infants in the three groups at 1 month, 3 months, 6 months, 12 months, 24 months, and 36 months were analyzed and compared, and the test results were recorded in detail. Result. There was no significant difference in 3-month-old WAZ and HAZ among the three groups (P>0.05). Within 6 months, the WAZ and HAZ values of the pure breastfeeding group and mixed feeding group were higher than those of the artificial feeding group (P<0.05). From 6 months to 12 months, the WAZ and HAZ values of the artificial feeding group were better than those of ...
Keywords	Biotechnology ; TP248.13-248.65 ; Biology (General) ; QH301-705.5
Subject code	590
Language	English
Publishing date	2022-01-01T00:00:00Z
Publisher	Hindawi Limited
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Antithrombotic therapy for secondary prevention of unprovoked venous thromboembolism

Dandan Li / Yi Liu / Yao Song / Aiping Wen

Annals of Medicine, Vol 54, Iss 1, Pp 253-

a systematic review and network meta-analysis of randomized controlled trials

2022 Volume 261

Abstract: Background Extended antithrombotic treatment is recommended for secondary prevention of unprovoked venous thromboembolism (VTE), however, there is no consensus on which antithrombotic strategy is preferable. Aim To compare the efficacy and safety of ... ...

Abstract	Background Extended antithrombotic treatment is recommended for secondary prevention of unprovoked venous thromboembolism (VTE), however, there is no consensus on which antithrombotic strategy is preferable. Aim To compare the efficacy and safety of different antithrombotic strategies for secondary prevention unprovoked VTE. Methods Cochrane Central Register of Controlled Trials, Embase, and MEDLINE were systematically searched from inception to 22 July 2020 for randomized controlled trials (RCTs) that compared the efficacy and/or safety of extended antithrombotic strategies including aspirin, warfarin and direct oral anticoagulants (DOACs) for secondary prevention of unprovoked VTE. The primary outcome was risk of major bleeding and the secondary outcomes were risks of recurrent VTE and all-cause death. Odds ratios (ORs) and 95% confidence intervals (CIs) were estimated using pairwise and network meta-analysis with random effect. Possible ranking of extended antithrombotic strategies was plotted using the surface under the cumulative ranking curve and mean ranks. Results Seventeen RCTs met the inclusion criteria, and meta-analysis results showed that warfarin was associated with significantly higher risk of major bleeding than placebo/observation (OR 2.71, 95% CI 1.32–5.55) or apixaban (OR 10.65, 95% CI 1.06–107.13). Apixaban and low-apixaban were the top two strategies according to the ranking of major bleeding. Warfarin (OR 0.25, 95%CI 0.13–0.49), rivaroxaban (OR 0.18, 95%CI 0.03–0.90), apixaban (OR 0.18, 95%CI 0.04–0.85) and low-apixaban (OR 0.18, 95%CI 0.04–0.82) were related to significantly lower risk than placebo/observation; edoxaban was non-inferior to warfarin on the risk of recurrent VTE. Furthermore, apixaban was linked with significantly lower risk of all-cause death than placebo/observation (OR 0.29, 95% CI 0.09–0.88). Conclusion Apixaban showed superiority to other antithrombotic strategies on major bleeding and all-cause death for secondary prevention of unprovoked VTE. Further studies are ...
Keywords	secondary prevention ; doac ; unprovoked vte ; network meta-analysis ; Medicine ; R
Subject code	610
Language	English
Publishing date	2022-12-01T00:00:00Z
Publisher	Taylor & Francis Group
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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