Article ; Online: The Anticonvulsant Lamotrigine Reduces Bout-Like Alcohol Drinking in Rats.
Alcohol and alcoholism (Oxford, Oxfordshire)
2021 Volume 57, Issue 2, Page(s) 242–245
Abstract: We used an optical lickometer system to study drinking microstructure and effect of lamotrigine in voluntary alcohol-drinking rats. We showed that, similar to humans, animals differ by their drinking microstructure where some consume alcohol exclusively ... ...
| Abstract | We used an optical lickometer system to study drinking microstructure and effect of lamotrigine in voluntary alcohol-drinking rats. We showed that, similar to humans, animals differ by their drinking microstructure where some consume alcohol exclusively in a bout-like patterns. The study suggests that anticonvulsants, such as lamotrigine, may be one treatment strategy specifically affecting this type of drinking. |
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| MeSH term(s) | Alcohol Drinking/drug therapy ; Animals ; Anticonvulsants/pharmacology ; Anticonvulsants/therapeutic use ; Ethanol ; Lamotrigine ; Rats | |||||
| Chemical Substances | Anticonvulsants ; Ethanol (3K9958V90M) ; Lamotrigine (U3H27498KS) | |||||
| Language | English | |||||
| Publishing date | 2021-10-30 | |||||
| Publishing country | England | |||||
| Document type | Journal Article | |||||
| ZDB-ID | 604956-4 | |||||
| ISSN | 1464-3502 ; 0309-1635 ; 0735-0414 | |||||
| ISSN (online) | 1464-3502 | |||||
| ISSN | 0309-1635 ; 0735-0414 | |||||
| DOI | 10.1093/alcalc/agab073 | |||||
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| Database | MEDical Literature Analysis and Retrieval System OnLINE |
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