LIVIVO - The Search Portal for Life Sciences

zur deutschen Oberfläche wechseln
Advanced search

Search results

Result 1 - 10 of total 18

Search options

  1. Article ; Online: El tratamiento informativo de las protestas en Colombia de 2021 en la prensa española

    Juan C. Figuereo-Benítez / Jair Esquiaqui-Buelvas / Daniel Moya-López / Rosalba Mancinas-Chávez

    Disertaciones, Vol 17, Iss

    El País, El Mundo, La Vanguardia y ABC

    2023  Volume 1

    Abstract: El 28 de abril de 2021 se inició la ola de protestas más importante de la historia reciente de Colombia: el Paro Nacional. La reforma tributaria fue el principal punto de conflicto, que luego se trasladó a las políticas neoliberales del gobierno de Iván ... ...

    Abstract El 28 de abril de 2021 se inició la ola de protestas más importante de la historia reciente de Colombia: el Paro Nacional. La reforma tributaria fue el principal punto de conflicto, que luego se trasladó a las políticas neoliberales del gobierno de Iván Duque, la violencia policial y la desigualdad, entre otros asuntos. Las protestas se cobraron la vida de más de 60 personas y movilizaron a miles de ciudadanos en todo el país, lo que acaparó la atención de la prensa nacional e internacional. Este artículo analiza el tratamiento informativo que los diarios de tirada nacional en España El País, El Mundo, La Vanguardia y abc concedieron a las protestas, para valorar qué importancia le otorgaron y apuntar de qué manera contribuyeron al conocimiento informativo de los españoles. La investigación se apoya en un análisis de contenido cuantitativo, en el que además de analizar la cobertura periodística se establece una comparación entre los cuatro periódicos seleccionados durante el primer mes desde el estallido. Las primeras conclusiones muestran que, si bien la cobertura fue casi diaria, no se abordó el tema en profundidad.
    Keywords Colombia ; paro nacional ; protestas ; cobertura periodística ; prensa española ; Communication. Mass media ; P87-96 ; Social Sciences ; H
    Language English
    Publishing date 2023-12-01T00:00:00Z
    Publisher Universidad del Rosario; Universidad de los Andes de Venezuela; Universidad Complutense de Madrid
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    More links

    Kategorien

  2. Article ; Online: Assessing kidney development and disease using kidney organoids and CRISPR engineering

    Wajima Safi / Andrés Marco / Daniel Moya / Patricia Prado / Elena Garreta / Nuria Montserrat

    Frontiers in Cell and Developmental Biology, Vol

    2022  Volume 10

    Abstract: The differentiation of human pluripotent stem cells (hPSCs) towards organoids is one of the biggest scientific advances in regenerative medicine. Kidney organoids have not only laid the groundwork for various organ-like tissue systems but also provided ... ...

    Abstract The differentiation of human pluripotent stem cells (hPSCs) towards organoids is one of the biggest scientific advances in regenerative medicine. Kidney organoids have not only laid the groundwork for various organ-like tissue systems but also provided insights into kidney embryonic development. Thus, several protocols for the differentiation of renal progenitors or mature cell types have been established. Insights into the interplay of developmental pathways in nephrogenesis and determination of different cell fates have enabled the in vitro recapitulation of nephrogenesis. Here we first provide an overview of kidney morphogenesis and patterning in the mouse model in order to dissect signalling pathways that are key to define culture conditions sustaining renal differentiation from hPSCs. Secondly, we also highlight how genome editing approaches have provided insights on the specific role of different genes and molecular pathways during renal differentiation from hPSCs. Based on this knowledge we further review how CRISPR/Cas9 technology has enabled the recapitulation and correction of cellular phenotypes associated with human renal disease. Last, we also revise how the field has positively benefited from emerging technologies as single cell RNA sequencing and discuss current limitations on kidney organoid technology that will take advantage from bioengineering solutions to help standardizing the use of this model systems to study kidney development and disease.
    Keywords pluripotent stem cells ; CRISPR ; nephrogenesis ; kidney engineering ; kidney organoids ; Biology (General) ; QH301-705.5
    Subject code 616
    Language English
    Publishing date 2022-09-01T00:00:00Z
    Publisher Frontiers Media S.A.
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    More links

    Kategorien

  3. Article ; Online: EL NACIMIENTO DE LA PRENSA DE EMPRESA EN ANDALUCÍA DURANTE LA RESTAURACIÓN. ANÁLISIS ESTRUCTURAL DE LA PROPIEDAD DE SUS PRINCIPALES CABECERAS

    Rosalba Mancinas-Chávez / Daniel Moya-López

    Cuadernos de Ilustración y Romanticismo, Vol 24, Pp 521-

    2018  Volume 539

    Abstract: In the last decades of the 19th century, the business press opened a new stage in the history of journalism. It was not only a change in management, but also a conceptual change in the way of conceiving journalism and perceiving information. This New ... ...

    Abstract In the last decades of the 19th century, the business press opened a new stage in the history of journalism. It was not only a change in management, but also a conceptual change in the way of conceiving journalism and perceiving information. This New Journalism required a strong investment, the involvement of businessmen and politicians. This fact created a network of external dependencies that compromised its independence, the germ of what we call now media structure. In the Andalusian case it was not different, a socio-economic, political and media elite was formed. This article outlines the situation of the property of the main Andalusian newspapers of the time from an unusual theoretical perspective.
    Keywords Andalusian press ; business press ; New Journalism ; history of journalism ; Bourbon Restoration ; media structure ; History (General) and history of Europe ; D ; History (General) ; D1-2009 ; Modern history ; 1453- ; D204-475
    Subject code 900
    Language Spanish
    Publishing date 2018-12-01T00:00:00Z
    Publisher Universidad de Cádiz
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    More links

    Kategorien

  4. Article ; Online: EL NACIMIENTO DE LA PRENSA DE EMPRESA EN ANDALUCÍA DURANTE LA RESTAURACIÓN. ANÁLISIS ESTRUCTURAL DE LA PROPIEDAD DE SUS PRINCIPALES CABECERAS

    Rosalba Mancinas-Chávez / Daniel Moya-López

    Cuadernos de Ilustración y Romanticismo, Vol 24, Pp 521-

    2018  Volume 539

    Abstract: In the last decades of the 19th century, the business press opened a new stage in the history of journalism. It was not only a change in management, but also a conceptual change in the way of conceiving journalism and perceiving information. This New ... ...

    Abstract In the last decades of the 19th century, the business press opened a new stage in the history of journalism. It was not only a change in management, but also a conceptual change in the way of conceiving journalism and perceiving information. This New Journalism required a strong investment, the involvement of businessmen and politicians. This fact created a network of external dependencies that compromised its independence, the germ of what we call now media structure. In the Andalusian case it was not different, a socio-economic, political and media elite was formed. This article outlines the situation of the property of the main Andalusian newspapers of the time from an unusual theoretical perspective.
    Keywords Andalusian press ; business press ; New Journalism ; history of journalism ; Bourbon Restoration ; media structure ; History (General) and history of Europe ; D ; History (General) ; D1-2009 ; Modern history ; 1453- ; D204-475
    Subject code 900
    Language Spanish
    Publishing date 2018-12-01T00:00:00Z
    Publisher Universidad de Cádiz
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    More links

    Kategorien

  5. Article ; Online: Post-Fire Regeneration and Diversity Response to Burn Severity in Pinus halepensis Mill. Forests

    Sonsoles González-De Vega / Jorge de las Heras / Daniel Moya

    Forests, Vol 9, Iss 6, p

    2018  Volume 299

    Abstract: In recent decades, fire regimes have been modified by various factors such as changes in land use, global change or forest management policies. The vulnerability of Mediterranean terrestrial ecosystems is increasing due to more severe and frequent ... ...

    Abstract In recent decades, fire regimes have been modified by various factors such as changes in land use, global change or forest management policies. The vulnerability of Mediterranean terrestrial ecosystems is increasing due to more severe and frequent droughts. This study aimed to determine the plant response of ecosystems during the short-term post-fire period by relating alpha diversity, floristic richness and tree recruitment dynamics to burn severity 5 years after a wildfire. Our results conclude that in the short term, Pinus halepensis Mill. stands in southeastern Spain quickly recovered alpha diversity values, mainly in areas burned with low severity. We observed that moderate and high severities affected the ecosystem more significantly, showing higher values for the Shannon Index but lower for the Simpson index. Pine recruitment was higher in burned areas, and we found the highest number of Aleppo pine seedlings under a moderate burn severity. Post-fire regeneration functional groups (obligate seeders and resprouters) were promoted under moderate and high burn severity, increasing their abundance. Annual species (mainly herbs) colonized burned areas, persisting with higher presence under moderate burn severity. Restoration tools should be focused on reducing fire severity, mainly in areas at high risk of desertification, and promoting resistance, vulnerability and resilience of these ecosystems.
    Keywords burn severity ; fire ecology ; ecosystem recovery ; natural regeneration ; Aleppo pine recruitment ; post-fire restoration ; Plant ecology ; QK900-989
    Language English
    Publishing date 2018-05-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    More links

    Kategorien

  6. Article: Seasonal nutrient retranslocation in reforested Pinus halepensis Mill. stands in Southeast Spain

    de las Heras, Jorge / Daniel Moya / Enrique J. Hernández-Tecles

    New forests. 2017 May, v. 48, no. 3

    2017  

    Abstract: Retranslocation, resorption and relocation of nutrients are important adaptive mechanisms developed by plants to acquire the amount of the nutrients required for growth. They are usual mechanisms in deciduous and conifer trees that occur in Mediterranean ...

    Abstract Retranslocation, resorption and relocation of nutrients are important adaptive mechanisms developed by plants to acquire the amount of the nutrients required for growth. They are usual mechanisms in deciduous and conifer trees that occur in Mediterranean regions where drought periods are usual. Soil factors, environmental characteristics and species factors are key drivers of nutrient retranslocation in conifers but is not well understood how soil fertility or intraspecific competition influences the process. We studied retranslocation in Pinus halepensis Mill. stands showing different site quality (differences in climate and intraspecific competition) occurring in Southeast Spain. We monitored reforested mature Aleppo pine forests in stands with differences in site quality, climate and intraspecific competition. Stands were characterised, the content of nutrients of soil and green samples (twigs and pine needles) were recorded, and seasonal nutrient retranslocation was obtained. Site characteristics were related to growth rate and nutrient content of foliage and soil. We evaluated whether the retranslocation of nutrients from older to younger foliage was related to the current-year growth rate and to the nutritional status of the plant as influenced by intraspecific competition. Foliar macronutrient concentrations and the amount of retranslocated macronutrients were seasonal, with differences related to site quality and tree density. As a general trend, nutrient concentrations increased after drought (autumn) and decreased during the growth period (spring). However, some micronutrients (mainly Na and Fe) decreased during both periods. The retranslocation pattern in Aleppo pine reinforced the hypothesis that pine adaptations to drought- and fire-prone habitats are linked to the resilience of these forest types. We developed scientific knowledge to assist decision making in adaptive forest management; e.g. fertilizer recommendations or reforestation programmes.
    Keywords autumn ; branches ; climate ; conifer needles ; coniferous forests ; conifers ; decision making ; drought ; fertilizers ; habitats ; intraspecific competition ; iron ; nutrient content ; nutrients ; nutritional status ; Pinus halepensis ; reforestation ; resorption ; sodium ; soil ; soil fertility ; spring ; trees ; Spain
    Language English
    Dates of publication 2017-05
    Size p. 397-413.
    Publishing place Springer Netherlands
    Document type Article
    ZDB-ID 1038718-3
    ISSN 0169-4286
    ISSN 0169-4286
    DOI 10.1007/s11056-016-9564-2
    Database NAL-Catalogue (AGRICOLA)

    More links

    Kategorien

  7. Article ; Online: Nephroprotective Potential of Mesenchymal Stromal Cells and Their Extracellular Vesicles in a Murine Model of Chronic Cyclosporine Nephrotoxicity

    María José Ramírez-Bajo / Javier Martín-Ramírez / Stefania Bruno / Chiara Pasquino / Elisenda Banon-Maneus / Jordi Rovira / Daniel Moya-Rull / Marta Lazo-Rodriguez / Josep M. Campistol / Giovanni Camussi / Fritz Diekmann

    Frontiers in Cell and Developmental Biology, Vol

    2020  Volume 8

    Abstract: BackgroundCell therapies and derived products have a high potential in aiding tissue and organ repairing and have therefore been considered as potential therapies for treating renal diseases. However, few studies have evaluated the impact of these ... ...

    Abstract BackgroundCell therapies and derived products have a high potential in aiding tissue and organ repairing and have therefore been considered as potential therapies for treating renal diseases. However, few studies have evaluated the impact of these therapies according to the stage of chronic kidney disease. The aim of this study was to evaluate the renoprotective effect of murine bone marrow mesenchymal stromal cells (BM-MSCs), their extracellular vesicles (EVs) and EVs-depleted conditioned medium (dCM) in an aggressive mouse model of chronic cyclosporine (CsA) nephrotoxicity in a preventive and curative manner.MethodsAfter 4 weeks of CsA-treatment (75 mg/kg daily) mice developed severe nephrotoxicity associated with a poor survival rate of 25%, and characterized by tubular vacuolization, casts, and cysts in renal histology. BM-MSC, EVs and dCM groups were administered as prophylaxis or as treatment of CsA nephrotoxicity. The effect of the cell therapies was analyzed by assessing renal function, histological damage, apoptotic cell death, and gene expression of fibrotic mediators.ResultsCombined administration of CsA and BM-MSCs ameliorated the mice survival rates (6–15%), but significantly renal function, and histological parameters, translating into a reduction of apoptosis and fibrotic markers. On the other hand, EVs and dCM administration were only associated with a partial recovery of renal function or histological damage. Better results were obtained when used as treatment rather than as prophylactic regimen i.e., cell therapy was more effective once the damage was established.ConclusionIn this study, we showed that BM-MSCs induce an improvement in renal outcomes in an animal model of CsA nephrotoxicity, particularly if the inflammatory microenvironment is already established. EVs and dCM treatment induce a partial recovery, indicating that further experiments are required to adjust timing and dose for better long-term outcomes.
    Keywords bone marrow mesenchymal stem cells ; extracellular vesicles ; conditioned medium ; cyclosporine A ; nephrotoxicity ; Biology (General) ; QH301-705.5
    Subject code 616 ; 630
    Language English
    Publishing date 2020-05-01T00:00:00Z
    Publisher Frontiers Media S.A.
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    More links

    Kategorien

  8. Article ; Online: Impact of Mesenchymal Stromal Cells and Their Extracellular Vesicles in a Rat Model of Kidney Rejection

    Maria Jose Ramirez-Bajo / Jordi Rovira / Marta Lazo-Rodriguez / Elisenda Banon-Maneus / Valeria Tubita / Daniel Moya-Rull / Natalia Hierro-Garcia / Pedro Ventura-Aguiar / Federico Oppenheimer / Josep M. Campistol / Fritz Diekmann

    Frontiers in Cell and Developmental Biology, Vol

    2020  Volume 8

    Abstract: BackgroundMesenchymal stromal cells (MSCs) from different sources possess great therapeutic potential due to their immunomodulatory properties associated with allograft tolerance. However, a crucial role in this activity resides in extracellular vesicles ...

    Abstract BackgroundMesenchymal stromal cells (MSCs) from different sources possess great therapeutic potential due to their immunomodulatory properties associated with allograft tolerance. However, a crucial role in this activity resides in extracellular vesicles (EVs) and signaling molecules secreted by cells. This study aimed to evaluate the immunomodulatory properties of donor and recipient MSCs isolated from adipose tissue (AD) or bone marrow (BM) and their EVs on kidney outcome in a rat kidney transplant model.MethodsThe heterotopic-kidney-transplant Fisher-to-Lewis rat model (F-L) was performed to study mixed cellular and humoral rejection. After kidney transplantation, Lewis recipients were assigned to 10 groups; two control groups; four groups received autologous MSCs (either AD- or BM- MSC) or EVs (derived from both cell types); and four groups received donor-derived MSCs or EVs. AD and BM-EVs were purified by ultracentrifugation. Autologous cell therapies were administered three times intravenously; immediately after kidney transplantation, 4 and 8 weeks, whereas donor-derived cell therapies were administered once intravenously immediately after transplantation. Survival and renal function were monitored. Twelve weeks after kidney transplantation grafts were harvested, infiltrating lymphocytes were analyzed by flow cytometry and histological lesions were characterized.ResultsAutologous AD- and BM-MSCs, but not their EVs, prolonged graft and recipient survival in a rat model of kidney rejection. Autologous AD- and BM-MSCs significantly improved renal function during the first 4 weeks after transplantation. The amelioration of graft function could be associated with an improvement in tubular damage, as well as in T, and NK cell infiltration. On the other side, the application of donor-derived AD-MSC was harmful, and all rats died before the end of the protocol. AD-EVs did not accelerate the rejection. Contrary to autologous MSCs results, the single dose of donor-derived BM-MSCs is not enough to ameliorate kidney ...
    Keywords bone marrow ; adipose tissue ; mesenchymal stromal cells ; extracellular vesicles ; kidney transplantation ; immunomodulation ; Biology (General) ; QH301-705.5
    Subject code 610 ; 616
    Language English
    Publishing date 2020-01-01T00:00:00Z
    Publisher Frontiers Media S.A.
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    More links

    Kategorien

  9. Article ; Online: Post-Fire Recovery of Vegetation and Diversity Patterns in Semiarid Pinus halepensis Mill. Habitats after Salvage Logging

    Daniel Moya / Javier Sagra / Manuel Esteban Lucas-Borja / Pedro Antonio Plaza-Álvarez / Javier González-Romero / Jorge De Las Heras / Pablo Ferrandis

    Forests, Vol 11, Iss 1345, p

    2020  Volume 1345

    Abstract: After wildfires, emergency actions and post-fire management are implemented to mitigate fire damage. Salvage logging is a tool often applied to burned stands, but despite being a post-fire forest management tool to restore ecosystem functions, its ... ...

    Abstract After wildfires, emergency actions and post-fire management are implemented to mitigate fire damage. Salvage logging is a tool often applied to burned stands, but despite being a post-fire forest management tool to restore ecosystem functions, its ecological effects remain poorly understood. In the Mediterranean Basin, where land use and land-use change are bringing about changes in drought periods and fire regimes, optimal treatments should be included in adaptive management in order to increase resilience and reduce vulnerability. In July 2012, a mid- to high-burn severity fire burned almost 7000 ha of an Aleppo pine forest ( Pinus halepensis Mill.) in southeastern Spain. Five years later (late spring 2017), we designed an experimental study to monitor four stand categories on a burn severity basis (unburned mature stands, low-burn severity stands, and high-burn severity stands) and a salvage logging operation carried out 6 months after the fire in high-burn severity areas. We set 60 circular plots (15 in each treatment scenario) and 180 linear transects (3 per plot, 45 per scenario) to check the ecological facilitation of pine trees and snags (canopy size and/or perch effect). We estimated plant alpha diversity (floristic richness, abundance and dominance indices) and post-fire plant recovery (pine recruitment and adaptive traits). Fire depleted the system’s diversity, but in low-severity burning areas some basic functions remained intact (e.g., soil protection). We found that high-burn severity very negatively impacted ecosystem functions through the removal of duff and litter leaving unprotected soil. Collecting wood reduced pine regeneration and growth, which was considerable in the areas that suffered high-burn severity. The burned snags did not appear to act as perches resulting in seed dispersal. Obligate seeders were determined to be an efficient strategy for facing high-severity fires, whereas resprouters response showed no clear burn severity pattern despite being present in all the scenarios. ...
    Keywords pine recruitment ; wildfire recovery ; post-fire management ; pine saplings ; alpha diversity ; Plant ecology ; QK900-989
    Subject code 550
    Language English
    Publishing date 2020-12-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    More links

    Kategorien

  10. Article ; Online: Post-Fire Seedling Recruitment and Morpho-Ecophysiological Responses to Induced Drought and Salvage Logging in Pinus halepensis Mill. Stands

    Daniel Moya / Jorge de las Heras / Francisco R. López-Serrano / Pablo Ferrandis

    Forests, Vol 6, Iss 6, Pp 1858-

    2015  Volume 1877

    Abstract: Salvage logging is the commonest post-fire emergency action, but has unclear ecological effects. In the Mediterranean Basin, drought periods and fire regimes are changing and forest management should be adapted. In summer 2009, a mid-high severity fire ... ...

    Abstract Salvage logging is the commonest post-fire emergency action, but has unclear ecological effects. In the Mediterranean Basin, drought periods and fire regimes are changing and forest management should be adapted. In summer 2009, a mid-high severity fire burned 968 ha of Aleppo pine (Pinus halepensis Mill.) forest in southeast Spain, which was submitted to salvage logging six months later. In spring 2010, plots were set in untreated and logged areas to monitor the recruitment and survival of the main tree species and three companion species: Stipa tenacissima L. (resprouter), Cistus clusii Dunal and Rosmarinus officinalis L. (obligate seeders). We evaluated responses to different scenarios in relation to intensification of summer droughts and forest management to obtain differences in water stress, growth, and gas exchange to cope with summer drought. Drought was induced by using rain-exclusion shelters and recorded ecophysiological characteristics were obtained with a portable gas exchange system. The main tree species recruitment was poor, but companion species showed a high survival ratio. Lower water stress was found for obligate seeder seedlings, which was higher in logged areas with induced drought. The initial post-fire stage was similar for the studied areas. However, after two drought periods (2010 and 2011), significant differences were found in the morphological and ecophysiological responses. In the unmanaged area, the biggest size of individuals due to the most marked increases in height and coverage were observed mainly in resprouter S. tenacissima. In the area submitted to salvage logging, the growth ratios in plots with induced drought were lower, mainly for seeders. Greater productivity was related to higher transpiration, stomatal conductance, and net photosynthetic ratio, but lower water use efficiency was found in obligate seeders with no drought induction, and S. tenacissima obtained higher values in untreated areas. Our results confirm that both forest management and intensification of summer ...
    Keywords Wildfires ; adaptive forest management ; drought ; resilience ; ecophysiology ; Plant ecology ; QK900-989
    Subject code 580
    Language English
    Publishing date 2015-05-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    More links

    Kategorien

To top