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  1. Article ; Online: Left Atrial Appendage Occlusion in 2022: Nearing Prime Time?

    Daniels, Matthew J

    Cardiac electrophysiology clinics

    2023  Volume 15, Issue 2, Page(s) xiii–xiv

    MeSH term(s) Humans ; Atrial Appendage/surgery ; Stroke ; Atrial Fibrillation/surgery
    Language English
    Publishing date 2023-03-01
    Publishing country United States
    Document type Editorial
    ISSN 1877-9190
    ISSN (online) 1877-9190
    DOI 10.1016/j.ccep.2023.01.002
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Left Atrial Appendage Occlusion in 2022: Nearing Prime Time?

    Daniels, Matthew J

    Interventional cardiology clinics

    2022  Volume 11, Issue 2, Page(s) xi–xii

    MeSH term(s) Atrial Appendage ; Atrial Fibrillation/surgery ; Echocardiography, Transesophageal ; Humans
    Language English
    Publishing date 2022-03-11
    Publishing country Netherlands
    Document type Editorial
    ISSN 2211-7466
    ISSN (online) 2211-7466
    DOI 10.1016/j.iccl.2022.01.002
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: The Future of LAAC-In 5, 10, and 20 Years.

    Daniels, Matthew J / Parry-Jones, Adrian

    Cardiac electrophysiology clinics

    2023  Volume 15, Issue 2, Page(s) 215–227

    Abstract: Early experience with percutaneous LAA closure documented complication rates of ∼10%, with failure to implant devices in ∼10% of patients. These numbers are unrecognizable in contemporary practice due to the iterative changes made largely in the last 10 ... ...

    Abstract Early experience with percutaneous LAA closure documented complication rates of ∼10%, with failure to implant devices in ∼10% of patients. These numbers are unrecognizable in contemporary practice due to the iterative changes made largely in the last 10 years. Here we look forward to ask what might change, and when, to bring percutaneous LAA closure out of the niche early adopter centers into routine use. We consider the opportunity to incorporate different technologies into LAAc devices in the context of managing patient with atrial fibrillation. Finally, we consider how to make the procedure safer and more effective.
    MeSH term(s) Humans ; Stroke/etiology ; Atrial Fibrillation ; Prosthesis Design ; Septal Occluder Device/adverse effects ; Atrial Appendage ; Treatment Outcome
    Language English
    Publishing date 2023-04-19
    Publishing country United States
    Document type Journal Article ; Review
    ISSN 1877-9190
    ISSN (online) 1877-9190
    DOI 10.1016/j.ccep.2023.01.011
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Transitioning from clinical cardiology to industry: general considerations.

    Daniels, Matthew J / Harston, George / Franke, Jennifer

    Heart (British Cardiac Society)

    2023  Volume 109, Issue 4, Page(s) 330–331

    MeSH term(s) Humans ; Cardiology ; Cardiovascular System
    Language English
    Publishing date 2023-01-27
    Publishing country England
    Document type Journal Article
    ZDB-ID 1303417-0
    ISSN 1468-201X ; 1355-6037
    ISSN (online) 1468-201X
    ISSN 1355-6037
    DOI 10.1136/heartjnl-2022-321700
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    Ui IV Zs.40: Show issues Location:
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  5. Article ; Online: Career paths for cardiologists in industry: exploring opportunities in hospital management, medical device industry and biotech.

    Daniels, Matthew J / Sheikhzadeh, Sara / Franke, Jennifer

    Heart (British Cardiac Society)

    2023  Volume 109, Issue 18, Page(s) 1416–1417

    MeSH term(s) Humans ; Cardiologists ; Industry ; Career Choice ; Biotechnology ; Hospitals
    Language English
    Publishing date 2023-08-24
    Publishing country England
    Document type Journal Article
    ZDB-ID 1303417-0
    ISSN 1468-201X ; 1355-6037
    ISSN (online) 1468-201X
    ISSN 1355-6037
    DOI 10.1136/heartjnl-2022-322318
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    Zs.MO 112: Show issues

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  6. Article ; Online: The American College of Cardiology 2018; a Starbuckian ODYSSEY and a Black Barbershop.

    Daniels, Matthew J

    Cardiovascular research

    2018  Volume 114, Issue 6, Page(s) e44–e46

    MeSH term(s) Black or African American ; Animals ; Antihypertensive Agents/therapeutic use ; Cardiology/methods ; Cardiovascular Diseases/blood ; Cardiovascular Diseases/diagnosis ; Cardiovascular Diseases/ethnology ; Cardiovascular Diseases/genetics ; Clinical Trials as Topic ; Community Health Services ; Disease Models, Animal ; Female ; Humans ; Hygiene ; Hypolipidemic Agents/therapeutic use ; Male ; Pharmacogenetics ; Sex Factors ; Translational Research, Biomedical
    Chemical Substances Antihypertensive Agents ; Hypolipidemic Agents
    Language English
    Publishing date 2018-04-12
    Publishing country England
    Document type Congress ; Research Support, Non-U.S. Gov't
    ZDB-ID 80340-6
    ISSN 1755-3245 ; 0008-6363
    ISSN (online) 1755-3245
    ISSN 0008-6363
    DOI 10.1093/cvr/cvy072
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    Zs.A 565: Show issues Location:
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  7. Article ; Online: The Future of LAAC-In 5, 10, and 20 Years.

    Daniels, Matthew J / Parry-Jones, Adrian

    Interventional cardiology clinics

    2022  Volume 11, Issue 2, Page(s) 219–231

    Abstract: Early experience with percutaneous LAA closure documented complication rates of ∼10%, with failure to implant devices in ∼10% of patients. These numbers are unrecognizable in contemporary practice due to the iterative changes made largely in the last 10 ... ...

    Abstract Early experience with percutaneous LAA closure documented complication rates of ∼10%, with failure to implant devices in ∼10% of patients. These numbers are unrecognizable in contemporary practice due to the iterative changes made largely in the last 10 years. Here we look forward to ask what might change, and when, to bring percutaneous LAA closure out of the niche early adopter centers into routine use. We consider the opportunity to incorporate different technologies into LAAc devices in the context of managing patient with atrial fibrillation. Finally, we consider how to make the procedure safer and more effective.
    MeSH term(s) Atrial Appendage ; Atrial Fibrillation/complications ; Humans
    Language English
    Publishing date 2022-03-10
    Publishing country Netherlands
    Document type Journal Article ; Review
    ISSN 2211-7466
    ISSN (online) 2211-7466
    DOI 10.1016/j.iccl.2021.11.011
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Feasibility of Using Adjunctive Optogenetic Technologies in Cardiomyocyte Phenotyping - from the Single Cell to the Whole Heart.

    Bub, Gil / Daniels, Matthew J

    Current pharmaceutical biotechnology

    2019  Volume 21, Issue 9, Page(s) 752–764

    Abstract: In 1791, Galvani established that electricity activated excitable cells. In the two centuries that followed, electrode stimulation of neuronal, skeletal and cardiac muscle became the adjunctive method of choice in experimental, electrophysiological, and ... ...

    Abstract In 1791, Galvani established that electricity activated excitable cells. In the two centuries that followed, electrode stimulation of neuronal, skeletal and cardiac muscle became the adjunctive method of choice in experimental, electrophysiological, and clinical arenas. This approach underpins breakthrough technologies like implantable cardiac pacemakers that we currently take for granted. However, the contact dependence, and field stimulation that electrical depolarization delivers brings inherent limitations to the scope and experimental scale that can be achieved. Many of these were not exposed until reliable in vitro stem-cell derived experimental materials, with genotypes of interest, were produced in the numbers needed for multi-well screening platforms (for toxicity or efficacy studies) or the 2D or 3D tissue surrogates required to study propagation of depolarization within multicellular constructs that mimic clinically relevant arrhythmia in the heart or brain. Here the limitations of classical electrode stimulation are discussed. We describe how these are overcome by optogenetic tools which put electrically excitable cells under the control of light. We discuss how this enables studies in cardiac material from the single cell to the whole heart scale. We review the current commercial platforms that incorporate optogenetic stimulation strategies, and summarize the global literature to date on cardiac applications of optogenetics. We show that the advantages of optogenetic stimulation relevant to iPS-CM based screening include independence from contact, elimination of electrical stimulation artefacts in field potential measuring approaches such as the multi-electrode array, and the ability to print re-entrant patterns of depolarization at will on 2D cardiomyocyte monolayers.
    MeSH term(s) Animals ; Electric Stimulation ; Electrophysiologic Techniques, Cardiac/instrumentation ; Electrophysiologic Techniques, Cardiac/methods ; Feasibility Studies ; Heart/physiology ; Humans ; Myocytes, Cardiac/physiology ; Neurons/physiology ; Optogenetics/instrumentation ; Optogenetics/methods
    Language English
    Publishing date 2019-04-05
    Publishing country Netherlands
    Document type Journal Article ; Review
    ZDB-ID 2132197-8
    ISSN 1873-4316 ; 1389-2010
    ISSN (online) 1873-4316
    ISSN 1389-2010
    DOI 10.2174/1389201020666190405182251
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 6212: Show issues Location:
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  9. Article ; Online: Myosin Modulation in Hypertrophic Cardiomyopathy and Systolic Heart Failure: Getting Inside the Engine.

    Daniels, Matthew J / Fusi, Luca / Semsarian, Christopher / Naidu, Srihari S

    Circulation

    2021  Volume 144, Issue 10, Page(s) 759–762

    MeSH term(s) Cardiomyopathy, Hypertrophic/physiopathology ; Cardiomyopathy, Hypertrophic/therapy ; Heart Failure, Systolic/physiopathology ; Heart Failure, Systolic/therapy ; Humans ; Myofibrils/metabolism ; Myosins/metabolism
    Chemical Substances Myosins (EC 3.6.4.1)
    Language English
    Publishing date 2021-09-07
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't ; Review
    ZDB-ID 80099-5
    ISSN 1524-4539 ; 0009-7322 ; 0069-4193 ; 0065-8499
    ISSN (online) 1524-4539
    ISSN 0009-7322 ; 0069-4193 ; 0065-8499
    DOI 10.1161/CIRCULATIONAHA.121.056324
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Reperfusion of ST-Segment-Elevation Myocardial Infarction in the COVID-19 Era: Business as Usual?

    Daniels, Matthew J / Cohen, Mauricio G / Bavry, Anthony A / Kumbhani, Dharam J

    Circulation

    2020  Volume 141, Issue 24, Page(s) 1948–1950

    MeSH term(s) Betacoronavirus ; COVID-19 ; Coronavirus Infections/epidemiology ; Coronavirus Infections/therapy ; Fibrinolytic Agents/therapeutic use ; Health Personnel/standards ; Humans ; Occupational Exposure/adverse effects ; Occupational Exposure/prevention & control ; Pandemics ; Percutaneous Coronary Intervention/adverse effects ; Pneumonia, Viral/epidemiology ; Pneumonia, Viral/therapy ; SARS-CoV-2 ; ST Elevation Myocardial Infarction/epidemiology ; ST Elevation Myocardial Infarction/therapy
    Chemical Substances Fibrinolytic Agents
    Keywords covid19
    Language English
    Publishing date 2020-04-13
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 80099-5
    ISSN 1524-4539 ; 0009-7322 ; 0069-4193 ; 0065-8499
    ISSN (online) 1524-4539
    ISSN 0009-7322 ; 0069-4193 ; 0065-8499
    DOI 10.1161/CIRCULATIONAHA.120.047122
    Database MEDical Literature Analysis and Retrieval System OnLINE

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