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  1. Book ; Online: Penyakit Menular dan Covid-19

    Danu, Arya

    2020  

    Abstract: Virus Corona adalah bagian dari keluarga virus yang menyebabkan penyakit pada hewan ataupun pada manusia. Di indonesia, masih melawan virus Corona hingga saat ini, begitupun juga di negara-negara lain. Jumlah kasus virus Corona terus bertambah dengan ... ...

    Abstract Virus Corona adalah bagian dari keluarga virus yang menyebabkan penyakit pada hewan ataupun pada manusia. Di indonesia, masih melawan virus Corona hingga saat ini, begitupun juga di negara-negara lain. Jumlah kasus virus Corona terus bertambah dengan beberapa melaporkan kesembuhan, tapi tak sedikit yang meninggal. Usaha penanganan dan pencegahan terus dilakukan demi melawan COVID-19 dengan gejala mirip flu.
    Keywords covid19
    Publisher Center for Open Science
    Publishing country us
    Document type Book ; Online
    DOI 10.31219/osf.io/c9mys
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  2. Article ; Online: Sensitivity, specificity, and accuracy of molecular profiling on circulating cell-free DNA in refractory or relapsed multiple myeloma patients, results of MM-EP1 study.

    Quivoron, C / Michot, J-M / Danu, A / Lecourt, H / Saada, V / Saleh, K / Vergé, V / Cotteret, S / Bernard, O A / Ribrag, V

    Leukemia & lymphoma

    2024  , Page(s) 1–11

    Abstract: As a promising alternative to bone marrow aspiration (BMA), mutational profiling on blood-derived circulating cell-free tumor DNA (cfDNA) is a harmless and simple technique to monitor molecular response and treatment resistance of patients with ... ...

    Abstract As a promising alternative to bone marrow aspiration (BMA), mutational profiling on blood-derived circulating cell-free tumor DNA (cfDNA) is a harmless and simple technique to monitor molecular response and treatment resistance of patients with refractory/relapsed multiple myeloma (R/R MM). We evaluated the sensitivity and specificity of cfDNA compared to BMA CD138 positive myeloma plasma cells (PCs) in a series of 45 R/R MM patients using the 29-gene targeted panel (AmpliSeq) NGS.
    Language English
    Publishing date 2024-03-03
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1042374-6
    ISSN 1029-2403 ; 1042-8194
    ISSN (online) 1029-2403
    ISSN 1042-8194
    DOI 10.1080/10428194.2024.2320258
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Incidence, characteristics, management and outcome of patients with follicular lymphoma with tumor epidural compression, a study on 22 cases.

    Gueiderikh, A / Ung, M / Lazarovici, J / Danu, A / Ghez, D / Saleh, K / Dragani, M / Noël, N / Bigenwald, C / Willekens, C / Ribrag, V / Michot, J-M / Martin, V

    Cancer radiotherapie : journal de la Societe francaise de radiotherapie oncologique

    2023  Volume 27, Issue 5, Page(s) 370–375

    Abstract: Purpose: Follicular lymphoma (FL) is one of the most common lymphoma. Occasionally, FL is associated with tumoral epidural compression and management of these patients remain poorly codified. This study aims to report incidence, clinical characteristics, ...

    Abstract Purpose: Follicular lymphoma (FL) is one of the most common lymphoma. Occasionally, FL is associated with tumoral epidural compression and management of these patients remain poorly codified. This study aims to report incidence, clinical characteristics, management and outcomes of patients with FL and tumoral epidural compression.
    Material and methods: Observational, retrospective cohort study of adult patients with FL and epidural tumor compression, treated in a French Institute over the last 20 years (2000-2021).
    Results: Between 2000 and 2021, 1382 patients with FL were followed by the haematological department. Of them, 22 (1.6%) patients (16 men and 6 women) had follicular lymphoma with epidural tumor compression. At epidural tumor compression occurrence, 8/22 (36%) patients had a neurological clinical deficit (motor, sensory or sphincter function) and 14/22 (64%) had tumor pain. All patients were treated with immuno-chemotherapy; the main regimen being used was R-CHOP plus high dose IV methotrexate in 16/22 (73%) patients. Radiotherapy for tumor epidural compression was performed in 19/22 (86%) patients. With a median follow-up of 60 months (range=[1-216]), 5 year local tumor relapse free survival was achieved in 65% (95% CI 47-90%) of patients. The median PFS was of 36 months (95% CI 24-NA) and 5 years OS estimate was 79% (95% CI 62-100%). Two patients developed a relapse at a second epidural site.
    Conclusion: FL with tumoral epidural compression reached 1.6% of all FL patients. Management based on immuno-chemotherapy with radiotherapy appeared to produce comparable outcomes with the general FL population.
    MeSH term(s) Adult ; Female ; Humans ; Male ; Antineoplastic Combined Chemotherapy Protocols/therapeutic use ; Doxorubicin ; Epidural Neoplasms/drug therapy ; Incidence ; Lymphoma, Follicular/radiotherapy ; Neoplasm Recurrence, Local/drug therapy ; Retrospective Studies ; Rituximab/therapeutic use ; Treatment Outcome
    Chemical Substances Doxorubicin (80168379AG) ; Rituximab (4F4X42SYQ6)
    Language English
    Publishing date 2023-05-06
    Publishing country France
    Document type Journal Article ; Observational Study
    ZDB-ID 1397169-4
    ISSN 1769-6658 ; 1278-3218
    ISSN (online) 1769-6658
    ISSN 1278-3218
    DOI 10.1016/j.canrad.2023.04.004
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Análisis de un espacio público de uso juvenil. El botellódromo en granada/Analysis of a public space for youth use. The botellódromo in granada

    Carmen Egea Jiménez / Danú A. Fabre Platas

    Geografares, Iss

    2018  Volume 26

    Abstract: RESUMEN El trabajo analiza cómo se construye socialmente un espacio público usado por jóvenes, el botellódromo de Granada. Para el análisis se usa: bibliografía, noticias de prensa y entrevistas a jóvenes que frecuentan este espacio. Los resultados ... ...

    Abstract RESUMEN El trabajo analiza cómo se construye socialmente un espacio público usado por jóvenes, el botellódromo de Granada. Para el análisis se usa: bibliografía, noticias de prensa y entrevistas a jóvenes que frecuentan este espacio. Los resultados señalan, por un lado, que los medios de comunicación (españoles) inciden en los aspectos más negativos y a veces “criminalizante” de la actividad; y, por otro, que para los jóvenes significa un ritual de paso en el inicio de una etapa de vida adulta y universitaria a través del ocio. Palabras clave: espacio público; jóvenes; botellódromo. ABSTRACT This article analyzes the social construction of a public space, located in the city of Granada and frequented mainly by young people: the “botellódromo”. The main sources and tools of the research were the bibliographic and hemerographic survey and interviews with the regulars. The results indicate that the Spanish media highlight the most negative and sometimes “criminalizing” aspects of the activity. On the other hand, for the young people, attendance at this place means a ritual of passage to adulthood and university life, through leisure. Keywords: public space; youth; “bottellódromo”.
    Keywords Geography. Anthropology. Recreation ; G ; Geography (General) ; G1-922
    Language Spanish
    Publishing date 2018-08-01T00:00:00Z
    Publisher Editora da Geografia
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  5. Article ; Online: Comparison between the European Central Bank as a New Monetary Experiment and other Major - Central Banks - US Federal Reserve and Bank of Japan

    Tache I. / Danu A.L.

    Bulletin of the Transilvania University of Brasov. Series V : Economic Sciences, Vol 7(56), Iss 2, Pp 295-

    2014  Volume 302

    Abstract: Our goal is to make a survey of three major central banks practices and to emphasize both the different national characteristics and the similarities derived from the global changes of financial environment. Using a descriptive methodology, the ... ...

    Abstract Our goal is to make a survey of three major central banks practices and to emphasize both the different national characteristics and the similarities derived from the global changes of financial environment. Using a descriptive methodology, the comparison will concern the central banks’ goals, the institutional and organizational structures, strategies and tools of monetary policy
    Keywords European Central Bank ; Federal Reserve System ; Bank of Japan. ; Bank of Japan ; Economic theory. Demography ; HB1-3840 ; Economics as a science ; HB71-74
    Language English
    Publishing date 2014-12-01T00:00:00Z
    Publisher Transilvania University Press
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  6. Article ; Online: Big sized players on the European Union’s financial advisory market

    Nicolae, C. / Danu, A.

    Bulletin of the Transilvania University of Brasov. Series V : Economic Sciences, Vol 6(55), Iss 1, Pp 133-

    2013  Volume 138

    Abstract: The paper presents the activity and the objectives of “The Big Four” Group of Financial Advisory Firms. The “Big Four” are the four largest international professional services networks in accountancy and professional services, offering audit, assurance, ... ...

    Abstract The paper presents the activity and the objectives of “The Big Four” Group of Financial Advisory Firms. The “Big Four” are the four largest international professional services networks in accountancy and professional services, offering audit, assurance, tax, consulting, advisory, actuarial, corporate finance and legal services. They handle the vast majority of audits for publicly traded companies as well as many private companies, creating an oligopoly in auditing large companies. It is reported that the Big Four audit all but one of the companies that constitute the FTSE 100, and 240 of the companies in the FTSE 250, an index of the leading mid-cap listing companies.
    Keywords financial advisory services ; market ; financial expert ; player market ; Economic theory. Demography ; HB1-3840 ; Economics as a science ; HB71-74
    Language English
    Publishing date 2013-06-01T00:00:00Z
    Publisher Transilvania University Press
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  7. Article: Precision Medicine Approach Based on Molecular Alterations for Patients with Relapsed or Refractory Multiple Myeloma: Results from the MM-EP1 Study.

    Andreozzi, Fabio / Dragani, Matteo / Quivoron, Cyril / Le Bras, Fabien / Assi, Tarek / Danu, Alina / Belhadj, Karim / Lazarovici, Julien / Cotteret, Sophie / Bernard, Olivier A / Ribrag, Vincent / Michot, Jean-Marie

    Cancers

    2023  Volume 15, Issue 5

    Abstract: Background: Despite that cytogenetic and molecular analysis of tumor cells can rapidly identify recurring molecular abnormalities, no personalized therapy is currently available in the setting of relapsed/refractory multiple myeloma (r/r MM).: Methods! ...

    Abstract Background: Despite that cytogenetic and molecular analysis of tumor cells can rapidly identify recurring molecular abnormalities, no personalized therapy is currently available in the setting of relapsed/refractory multiple myeloma (r/r MM).
    Methods: MM-EP1 is a retrospective study aimed at comparing a personalized molecular-oriented (MO) versus a non-molecular-oriented (no-MO) approach in r/r MM. Actionable molecular targets and their associated therapies were the BRAF V600E mutation and BRAF inhibitors; t(11;14)(q13;q32) and BCL2 inhibitors; and t(4;14)(p16;q32) with FGFR3 fusion/rearrangements and FGFR3 inhibitors.
    Results: One hundred three highly pretreated r/r MM patients with a median age of 67 years (range 44-85) were included. Seventeen (17%) patients were treated using an MO approach with BRAF inhibitors (vemurafenib or dabrafenib,
    Conclusion: Despite the low number of patients treated with an MO approach, this study highlights the strengths and weakness of a molecular-targeted approach for the treatment of multiple myeloma. Widespread biomolecular techniques and improvement of precision medicine treatment algorithms could improve selection for precision medicine in myeloma.
    Language English
    Publishing date 2023-02-28
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2527080-1
    ISSN 2072-6694
    ISSN 2072-6694
    DOI 10.3390/cancers15051508
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Los espacios de intercambio. Los tianguis de Páztcuaro (Michoacán, México), entre la tradición y las estrategias de supervivencia

    Danú A. Fabre Platas / Carmen Egea Jiménez

    Documents d'Anàlisi Geogràfica, Vol 61, Iss 2, Pp 265-

    2015  Volume 287

    Abstract: La intención del presente artículo es mostrar procesos sociales locales en coexistencia con las realidades posmodernas globales, donde parece persistir una lógica egocéntrica e hiperespecializada irremediable. Esta idea parte de observar la pervivencia y ...

    Abstract La intención del presente artículo es mostrar procesos sociales locales en coexistencia con las realidades posmodernas globales, donde parece persistir una lógica egocéntrica e hiperespecializada irremediable. Esta idea parte de observar la pervivencia y la renovación de solidaridades tradicionales en espacios que se asumen globalizados, pero en los que persisten o se recuperan tejidos sociales históricos donde la memoria colectiva actúa como resistencia cultural. En este contexto, se analizan, a través de la observación participante, dos tianguis localizados en el área purhepecha y protagonizados por la comunidad purhe: el tianguis del Santuario, en la ciudad de Páztcuaro, y el mojtakuntani o tianguis regional purhepecha, desarrollado por las poblaciones cercanas al lago de Pátzcuaro (Estado de Michoacán, México). Los tianguis son mercados públicos que se asumen aquí como espacios de intercambio y tienen la particularidad de que la actividad económica de adquisición de bienes se realiza a través del trueque, sin intervención de la moneda como valor de cambio.
    Keywords espais d’intercanvi ; economia glocal ; economia camperola ; resistència indígena ; tianguis ; Geography (General) ; G1-922
    Language Catalan
    Publishing date 2015-05-01T00:00:00Z
    Publisher Universitat Autònoma de Barcelona. Departament de Geografia
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  9. Article ; Online: Vulnerabilidad, reconstrucciones étnicas y estrategias de sobrevivencia en el trópico húmedo mexicano

    Danú A. Fabre Platas

    Cuadernos Geográficos, Iss 48, Pp 259-

    2011  Volume 274

    Keywords Environmental sciences ; GE1-350 ; Geography (General) ; G1-922
    Language English
    Publishing date 2011-01-01T00:00:00Z
    Publisher Universidad de Granada
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  10. Article ; Online: Investigational drugs for T-cell lymphoma.

    Ghez, David / Danu, Alina / Ribrag, Vincent

    Expert opinion on investigational drugs

    2016  Volume 25, Issue 2, Page(s) 171–181

    Abstract: Introduction: Peripheral T-cell lymphomas (PTCL) represent a heterogeneous group of malignancies frequently associated with a poor outcome. The frontline treatment strategy for PTCL relies mostly on CHOP or CHOP-like regimens, which are associated with ... ...

    Abstract Introduction: Peripheral T-cell lymphomas (PTCL) represent a heterogeneous group of malignancies frequently associated with a poor outcome. The frontline treatment strategy for PTCL relies mostly on CHOP or CHOP-like regimens, which are associated with a high failure rate and frequent relapses.
    Areas covered: In this review, the authors present recently registered drugs and their positioning in the therapeutic armamentarium against PTCL and new drugs currently in development. The successful results in CD30-positive anaplastic large cell lymphomas suggest that a better characterization of these lymphomas could open new areas of efficient drug development.
    Expert opinion: Advances in the field of molecular biology have started to unravel the anomalies associated with T-cell malignancies. Recent knowledge on potential epigenetic modifiers like IDH2, which is frequently mutated in angioimmunoblastic T-cell lymphoma, opens new areas of research and confirms that epigenetic drugs could represent an attractive area of clinical research. The recently developed immune checkpoints regulators might represent another area of potential interest.
    MeSH term(s) Antineoplastic Agents/pharmacology ; Antineoplastic Agents/therapeutic use ; Drug Design ; Drugs, Investigational/pharmacology ; Drugs, Investigational/therapeutic use ; Epigenesis, Genetic ; Humans ; Lymphoma, T-Cell, Peripheral/drug therapy ; Lymphoma, T-Cell, Peripheral/genetics ; Lymphoma, T-Cell, Peripheral/pathology ; Molecular Biology
    Chemical Substances Antineoplastic Agents ; Drugs, Investigational
    Language English
    Publishing date 2016
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 1182884-5
    ISSN 1744-7658 ; 0967-8298 ; 1354-3784
    ISSN (online) 1744-7658
    ISSN 0967-8298 ; 1354-3784
    DOI 10.1517/13543784.2016.1121994
    Database MEDical Literature Analysis and Retrieval System OnLINE

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