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  1. Article ; Online: Conceptualising mental illness among University students of African, Caribbean and similar ethnic heritage in the United Kingdom.

    Dare, Oluwateniayo / Jidong, Dung Ezekiel / Premkumar, Preethi

    Ethnicity & health

    2022  Volume 28, Issue 4, Page(s) 522–543

    Abstract: Objective: Students of African, Caribbean and similar ethnicity (ACE) encounter unique mental health challenges within the Western higher education system, such as feeling constrained in social spaces and perceiving greater stigma about mental health. ... ...

    Abstract Objective: Students of African, Caribbean and similar ethnicity (ACE) encounter unique mental health challenges within the Western higher education system, such as feeling constrained in social spaces and perceiving greater stigma about mental health. Students of ACE are also resilient to mental health problems, such as depression, when enduring social inequality. This study aimed to conceptualise mental illness and help-seeking behaviours among university students in the United Kingdom (UK) in the context of their identity as ACE.
    Design: Six university students of ACE in the UK were interviewed about the meaning of mental illness, the influence of ACE culture on mental health and help-seeking by ACE students. Thematic analysis was applied from a socio-constructionist theoretical lens to interpret the interview transcripts.
    Results: Five main themes emerged, namely 'Perceived meanings and attitudes toward mental health problems', 'Beliefs about the non-existence of mental health problem and its spiritual attributions', 'Family dynamics and the 'silencing' of mental health problems', 'Help-seeking for mental health among people of ACE' and 'Stigma and discriminatory responses to mental health issues'. Participants expressed that mental health is an imported concept that people from ACE communities tend to shy away from. A reluctance to discuss mental health problems arose over fear of rejection from families and fear of not being understood by a mental health professional from a different cultural background.
    Conclusion: University students of ACE and their families struggle to adopt the Western conceptualisation of mental health. Consequently, there is poor awareness of mental health issues and stigma of mental illness among university students of ACE which pose a barrier to help-seeking for mental health. The limited sample size constrains the ability to draw sound conclusions. Nonetheless, a culturally sensitive conceptualisation of mental health is needed to address poor help-seeking for mental health among people of ACE.
    MeSH term(s) Humans ; Ethnicity/psychology ; Ethnicity/statistics & numerical data ; Mental Disorders/ethnology ; Mental Disorders/psychology ; Patient Acceptance of Health Care/ethnology ; Patient Acceptance of Health Care/statistics & numerical data ; Social Stigma ; Students/psychology ; Students/statistics & numerical data ; Universities ; United Kingdom ; Black People/psychology ; Black People/statistics & numerical data ; Caribbean People/psychology ; Caribbean People/statistics & numerical data ; Male ; Female ; Young Adult ; Adult ; Middle Aged
    Language English
    Publishing date 2022-07-31
    Publishing country England
    Document type Journal Article
    ZDB-ID 1497968-8
    ISSN 1465-3419 ; 1355-7858
    ISSN (online) 1465-3419
    ISSN 1355-7858
    DOI 10.1080/13557858.2022.2104817
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Glitazone Treatment Rescues Phenotypic Deficits in a Fly Model of Gaucher/Parkinson's Disease.

    Shola-Dare, Oluwanifemi / Bailess, Shelby / Flores, Carlos C / Vanderheyden, William M / Gerstner, Jason R

    International journal of molecular sciences

    2021  Volume 22, Issue 23

    Abstract: Parkinson's Disease (PD) is the most common movement disorder, and the strongest genetic risk factor for PD is mutations in the glucocerebrosidase gene ( ...

    Abstract Parkinson's Disease (PD) is the most common movement disorder, and the strongest genetic risk factor for PD is mutations in the glucocerebrosidase gene (
    MeSH term(s) Animals ; Drosophila melanogaster ; Gaucher Disease/drug therapy ; Gaucher Disease/etiology ; Gaucher Disease/pathology ; Glucosylceramidase/deficiency ; Humans ; Male ; Parkinson Disease/drug therapy ; Parkinson Disease/etiology ; Parkinson Disease/pathology ; Phenotype ; Thiazolidinediones/pharmacology
    Chemical Substances Thiazolidinediones ; Glucosylceramidase (EC 3.2.1.45)
    Language English
    Publishing date 2021-11-25
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2019364-6
    ISSN 1422-0067 ; 1422-0067 ; 1661-6596
    ISSN (online) 1422-0067
    ISSN 1422-0067 ; 1661-6596
    DOI 10.3390/ijms222312740
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Suppression of uric acid generation and blockade of glutathione dysregulation by L-arginine ameliorates dichlorvos-induced oxidative hepatorenal damage in rats.

    Saka, W A / Akhigbe, R E / Abidoye, A O / Dare, O S / Adekunle, A O

    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

    2021  Volume 138, Page(s) 111443

    Abstract: Dichlorvos is a known risk factor for organ toxicity. The liver and kidney are essential metabolic tissues but it is unclear whether or not there is associated redox dyshomeostasis in both organs in physiological and pathological states. Uric acid ... ...

    Abstract Dichlorvos is a known risk factor for organ toxicity. The liver and kidney are essential metabolic tissues but it is unclear whether or not there is associated redox dyshomeostasis in both organs in physiological and pathological states. Uric acid accumulation and glutathione dysregulation have been implicated in the aetiopathogenesis of organ damage. The antioxidant potentials of L-arginine have been shown in various conditions. The present study was thus designed to investigate the synchrony in hepatic and renal uric acid and glutathione status in dichlorvos-induced hepatorenal damage and to probe the possible therapeutic role of L-arginine. Twenty-one male Wistar rats were treated with standard rat diet and water, dichlorvos, or dichlorvos and L-arginine. Our findings revealed that dichlorvos significantly impaired hepatic and renal functions, increased hepatic and renal malondialdehyde, but reduced glutathione and activities of superoxide dismutase, catalase, and glutathione peroxidase. These events were accompanied by increased accumulation of plasma, hepatic, and renal uric acid as well as reduced body weight gain, and hepatic and renal weights. Histopathological examinations revealed hepatic and renal architectural derangement and cellular necrosis and degeneration in dichlorvos-exposed rats. Interestingly, L-arginine reversed dichlorvos-induced systemic, hepatic and renal synchronous redox dyshomeostasis. L-arginine administration also improved hepatic and renal cytoarchitecture. It is thus concluded that dichlorvos triggered synchronous uric acid generation and glutathione alterations in the liver and kidney. L-arginine confers protection against dichlorvos-induced hepatorenal damage via suppression of uric acid generation and blockade of glutathione dysregulation.
    MeSH term(s) Acute Kidney Injury/chemically induced ; Acute Kidney Injury/metabolism ; Acute Kidney Injury/prevention & control ; Animals ; Arginine/pharmacology ; Arginine/therapeutic use ; Chemical and Drug Induced Liver Injury/metabolism ; Chemical and Drug Induced Liver Injury/prevention & control ; Cholinesterase Inhibitors/toxicity ; Dichlorvos/toxicity ; Glutathione/antagonists & inhibitors ; Glutathione/metabolism ; Male ; Oxidative Stress/drug effects ; Oxidative Stress/physiology ; Rats ; Rats, Wistar ; Uric Acid/antagonists & inhibitors ; Uric Acid/metabolism
    Chemical Substances Cholinesterase Inhibitors ; Uric Acid (268B43MJ25) ; Dichlorvos (7U370BPS14) ; Arginine (94ZLA3W45F) ; Glutathione (GAN16C9B8O)
    Language English
    Publishing date 2021-03-02
    Publishing country France
    Document type Journal Article
    ZDB-ID 392415-4
    ISSN 1950-6007 ; 0753-3322 ; 0300-0893
    ISSN (online) 1950-6007
    ISSN 0753-3322 ; 0300-0893
    DOI 10.1016/j.biopha.2021.111443
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Do invasive bullfrogs in Victoria, British Columbia, Canada, show evidence of parasite release?

    Dare, O K / Forbes, M R

    Journal of helminthology

    2013  Volume 87, Issue 2, Page(s) 195–202

    Abstract: Few studies have examined vertebrate models of invasive species to explore parasite release as a proposed mechanism through which host species might become invasive. In this study, we examined evidence for parasite release in invasive American bullfrogs ( ...

    Abstract Few studies have examined vertebrate models of invasive species to explore parasite release as a proposed mechanism through which host species might become invasive. In this study, we examined evidence for parasite release in invasive American bullfrogs (Rana catesbeiana/Lithobates catesbeianus) from five sites in Victoria, British Columbia, Canada. We examined helminth species richness, as well as the prevalence, intensity and abundance of lung and kidney fluke infections. These flukes are expected to impose costs on host survival, growth and reproductive output. We compared measures of these parasite taxa with bullfrogs from Ontario and New Brunswick where they are endemic. Helminth species richness in bullfrogs from the Victoria sites was lower than in Ontario bullfrogs, but comparable to reported indices for other endemic populations. The prevalence of lung flukes (Haematoloechus spp.) in bullfrogs from Victoria was twice as high as was observed in the Ontario bullfrogs, and higher than has been reported from other endemic locations. In four of the five study sites in Victoria, numbers of Echinostoma spp. kidney cysts were lower than observed in endemic populations; however, the fifth site had uncharacteristically high numbers of cysts. In this study, there did not appear to be clear evidence to support parasite release using either parasite species numbers, or infection by specific parasite taxa. Instead, the invasive bullfrogs demonstrated high parasite species richness and high levels of infection for parasites known to be harmful to their hosts.
    MeSH term(s) Animals ; Biodiversity ; British Columbia/epidemiology ; Helminthiasis, Animal/epidemiology ; Helminthiasis, Animal/parasitology ; Helminths/classification ; Helminths/isolation & purification ; Kidney/parasitology ; Lung/parasitology ; Prevalence ; Rana catesbeiana/parasitology
    Language English
    Publishing date 2013-06
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 390188-9
    ISSN 1475-2697 ; 0022-149X
    ISSN (online) 1475-2697
    ISSN 0022-149X
    DOI 10.1017/S0022149X12000211
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: There is scope to improve undergraduate resuscitation and first aid training - findings from a survey of UK medical schools.

    Dare, Oliver / Aspinall, Mary / Ellis, Josephine / Graham, Blair

    Resuscitation

    2015  Volume 89, Page(s) e3

    MeSH term(s) Curriculum ; Education, Medical, Undergraduate ; First Aid ; Humans ; Resuscitation/education ; Schools, Medical ; Surveys and Questionnaires ; United Kingdom
    Language English
    Publishing date 2015-04
    Publishing country Ireland
    Document type Letter
    ZDB-ID 189901-6
    ISSN 1873-1570 ; 0300-9572
    ISSN (online) 1873-1570
    ISSN 0300-9572
    DOI 10.1016/j.resuscitation.2015.02.002
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Patterns of trematode and nematode lungworm infections in northern leopard frogs and wood frogs from Ontario, Canada.

    Dare, O K / Forbes, M R

    Journal of helminthology

    2009  Volume 83, Issue 4, Page(s) 339–343

    Abstract: In this study we examined trematode and nematode lung helminths commonly found in two species of host ranid frogs for competitive interactions. We examined 147 adult (breeding and non-breeding) and juvenile northern leopard frogs, and 84 breeding male ... ...

    Abstract In this study we examined trematode and nematode lung helminths commonly found in two species of host ranid frogs for competitive interactions. We examined 147 adult (breeding and non-breeding) and juvenile northern leopard frogs, and 84 breeding male wood frogs in Bishops Mills, Ontario for Haematoloechus spp. (Trematoda) and Rhabdias sp. (Nematoda) infections. A strong negative association between phyla of helminth was observed in breeding and juvenile northern leopard frogs, and also in breeding wood frogs, but not in non-breeding adult northern leopard frogs. Few hosts carried both types of worm concurrently. Thirteen northern leopard frogs carried dual infections, while 77 carried only one phylum of helminth. Twenty-seven wood frogs carried dual infections, while 54 carried only one phylum of helminth. We also observed spatial segregation of the two phyla in host lungs. Our study informs future research on the dynamics of interactions among lung helminths in these two host species.
    MeSH term(s) Analysis of Variance ; Animals ; Anura/parasitology ; Host-Parasite Interactions ; Lung Diseases, Parasitic/epidemiology ; Lung Diseases, Parasitic/veterinary ; Nematode Infections/epidemiology ; Ontario/epidemiology ; Prevalence ; Trematoda ; Trematode Infections/epidemiology
    Language English
    Publishing date 2009-12
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 390188-9
    ISSN 1475-2697 ; 0022-149X
    ISSN (online) 1475-2697
    ISSN 0022-149X
    DOI 10.1017/S0022149X09243495
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: Do invasive bullfrogs in Victoria, British Columbia, Canada, show evidence of parasite release?

    Dare, O.K / Forbes, M.R

    Journal of helminthology. 2013 June, v. 87, no. 2

    2013  

    Abstract: Few studies have examined vertebrate models of invasive species to explore parasite release as a proposed mechanism through which host species might become invasive. In this study, we examined evidence for parasite release in invasive American bullfrogs ( ...

    Abstract Few studies have examined vertebrate models of invasive species to explore parasite release as a proposed mechanism through which host species might become invasive. In this study, we examined evidence for parasite release in invasive American bullfrogs (Rana catesbeiana/Lithobates catesbeianus) from five sites in Victoria, British Columbia, Canada. We examined helminth species richness, as well as the prevalence, intensity and abundance of lung and kidney fluke infections. These flukes are expected to impose costs on host survival, growth and reproductive output. We compared measures of these parasite taxa with bullfrogs from Ontario and New Brunswick where they are endemic. Helminth species richness in bullfrogs from the Victoria sites was lower than in Ontario bullfrogs, but comparable to reported indices for other endemic populations. The prevalence of lung flukes (Haematoloechus spp.) in bullfrogs from Victoria was twice as high as was observed in the Ontario bullfrogs, and higher than has been reported from other endemic locations. In four of the five study sites in Victoria, numbers of Echinostoma spp. kidney cysts were lower than observed in endemic populations; however, the fifth site had uncharacteristically high numbers of cysts. In this study, there did not appear to be clear evidence to support parasite release using either parasite species numbers, or infection by specific parasite taxa. Instead, the invasive bullfrogs demonstrated high parasite species richness and high levels of infection for parasites known to be harmful to their hosts.
    Keywords Echinostoma ; Haematoloechus ; Lithobates catesbeianus ; hosts ; invasive species ; kidneys ; lung flukes ; models ; reproductive performance ; species diversity ; trematode infections ; vertebrates ; British Columbia ; New Brunswick ; Ontario
    Language English
    Dates of publication 2013-06
    Size p. 195-202.
    Publishing place Cambridge University Press
    Document type Article
    ZDB-ID 390188-9
    ISSN 1475-2697 ; 0022-149X
    ISSN (online) 1475-2697
    ISSN 0022-149X
    DOI 10.1017/S0022149X12000211
    Database NAL-Catalogue (AGRICOLA)

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  8. Article ; Online: Rates of development in male and female Wood Frogs and patterns of parasitism by lung nematodes.

    Dare, O K / Forbes, M R

    Parasitology

    2008  Volume 135, Issue 3, Page(s) 385–393

    Abstract: Researchers are becoming interested in testing whether investment in growth and/or development trades off against investment in parasite defence. We tested this idea by examining relations between development of Wood Frogs (Rana sylvatica) and ... ...

    Abstract Researchers are becoming interested in testing whether investment in growth and/or development trades off against investment in parasite defence. We tested this idea by examining relations between development of Wood Frogs (Rana sylvatica) and susceptibility to lung nematodes (Rhabdias ranae). Male and female frogs reared in outdoor mesocosms were the same length and mass at metamorphosis. However, males metamorphosed sooner than females. Lung nematodes were no more likely to penetrate male versus female metamorphs following controlled exposures, but males had higher intensities of adult female worms and the largest worms per host were, on average, of larger size in male metamorphs. Males that took longer to metamorphose carried higher numbers of worms in their lungs than males that metamorphosed early. In comparison, females that developed faster harboured more worms in their lungs than females that took longer to reach metamorphosis. Our results suggest that variation in susceptibility to lung nematodes is influenced by host sex and possibly also by sex-specific relations with developmental rate. Further, male hosts might prove to be a more important source of infective stages of worms than female hosts.
    MeSH term(s) Animals ; Disease Susceptibility ; Female ; Host-Parasite Interactions/physiology ; Lung Diseases, Parasitic/parasitology ; Lung Diseases, Parasitic/veterinary ; Male ; Metamorphosis, Biological ; Population Density ; Random Allocation ; Ranidae/parasitology ; Rhabditida Infections/parasitology ; Rhabditida Infections/veterinary ; Rhabditoidea/pathogenicity ; Rhabditoidea/physiology ; Sex Factors
    Language English
    Publishing date 2008-03
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 207627-5
    ISSN 1469-8161 ; 0031-1820
    ISSN (online) 1469-8161
    ISSN 0031-1820
    DOI 10.1017/S0031182007003836
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article: First Record of Parasites from Cougars (Puma concolor) in Manitoba, Canada

    Dare, O. K / W. G. Watkins

    Canadian field-naturalist. 2012 , v. 126, no. 4

    2012  

    Abstract: Cougars (Puma concolor) are a rare sighting in Manitoba. This is the first report on Cougar parasites in Manitoba and the first record of Taenia omissa for the province. These data provide an important baseline that will inform future research on ... ...

    Abstract Cougars (Puma concolor) are a rare sighting in Manitoba. This is the first report on Cougar parasites in Manitoba and the first record of Taenia omissa for the province. These data provide an important baseline that will inform future research on parasite profiles and predator–prey interactions between these large carnivores and other wildlife in the province.
    Keywords carnivores ; parasites ; predator-prey relationships ; Puma concolor ; Taenia ; wildlife ; Manitoba
    Language English
    Dates of publication 2012-10
    Size p. 324-327.
    Publishing place Ottawa Field-Naturalists' Club
    Document type Article
    ZDB-ID 2658336-7
    ISSN 0008-3550
    ISSN 0008-3550
    DOI 10.22621/cfn.v126i4.1378
    Database NAL-Catalogue (AGRICOLA)

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  10. Article ; Online: Appraisal of Widows Support Groups in Contemporary Societies

    Tayo O. George / Jonathan A. Odukoya / Albert O. Shaibu / O. C. Uche Onyekwere / Dare O. Omonijo

    Mediterranean Journal of Social Sciences, Vol 7, Iss

    A Study of Widows in Ota Metropolis

    2016  Volume 5

    Abstract: This paper examined the nature and quality of support rendered to widows during and after the mourning period by support groups in Ota. The role of support groups ranging from family members, friends, associations, religious institutions in widows’ ... ...

    Abstract This paper examined the nature and quality of support rendered to widows during and after the mourning period by support groups in Ota. The role of support groups ranging from family members, friends, associations, religious institutions in widows’ wellbeing was examined using survey questionnaire and in-depth interview. Findings from the study informed the basis for conclusion and recommendations for policy making and implementation at individual(s), groups, local, state and national levels in Nigeria DOI:10.5901/mjss.2016.v7n5p158
    Keywords Social Sciences ; H
    Language English
    Publishing date 2016-09-01T00:00:00Z
    Publisher richtmann publishing
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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