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Article ; Online: Effect of ionic strength on aggregation of nile red and coumarin 30 in aqueous medium: primary kinetic salt effect or salting-out effect?

Chattopadhyay, Nitin / Das, Arindam

RSC advances

2023 Volume 13, Issue 36, Page(s) 25159–25168

Abstract: The effect of ionic strength on the aggregation of planar dyes like nile red (NR) and coumarin-30 (C30) in aqueous medium has been explored. The dyes are known to undergo dimerization, resulting in fading of their respective colors in the visible range. ... ...

Abstract	The effect of ionic strength on the aggregation of planar dyes like nile red (NR) and coumarin-30 (C30) in aqueous medium has been explored. The dyes are known to undergo dimerization, resulting in fading of their respective colors in the visible range. The present study demonstrates that the fading process is accelerated appreciably upon increasing ionic strength of the solution through addition of soluble salts. Experiments consist of variation of cations (Na
Language	English
Publishing date	2023-08-23
Publishing country	England
Document type	Journal Article
ISSN	2046-2069
ISSN (online)	2046-2069
DOI	10.1039/d3ra03829g
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Article: Drawing the Linkage Between Women's Reproductive Health, Climate Change, Natural Disaster, and Climate-driven Migration: Focusing on Low- and Middle-income Countries - A Systematic Overview.

Afzal, Fahad / Das, Arindam / Chatterjee, Soumitra

Indian journal of community medicine : official publication of Indian Association of Preventive & Social Medicine

2024 Volume 49, Issue 1, Page(s) 28–38

Abstract: Background: One of the most important aspects of women's well-being and welfare is RSH (reproductive and sexual health). Reproductive health is not an exception to the threat that CCC (climate change and climate crisis) poses to numerous facets of ... ...

Abstract	Background: One of the most important aspects of women's well-being and welfare is RSH (reproductive and sexual health). Reproductive health is not an exception to the threat that CCC (climate change and climate crisis) poses to numerous facets of public health. Firstly, the present review seeks to identify the influence of climatic changes, natural disasters, and climate-driven migration on RSH. Secondly, to identify knowledge gaps regarding the same. Material and methods: Two databases (Scopus and PubMed) were scanned using Boolean operation. The literature search aimed to find records pertaining to topics of RSH and climate change. Using the PRISMA-ScR method, records were screened and shortlisted based on established inclusion criteria. This literature search was carried out in November 2022. In the shortlisted records, preference for the comprehensive review articles was given. Results: The present review is based on 38 records that collectively revealed that climate crisis and natural disasters have many negative impacts on female reproductive health. These effects are observed in different phases of life, ranging from teenage to menopause. The unique strength of the present review is that it draws a relationship between female reproductive health and the direct as well as indirect effects of the CCC. The available literature about LMICs is predominantly confined to drought, flood, and earthquake. Disasters like tsunamis, cyclones, and avalanches remain unexplored. Conclusion: From the available literature, it is quite evident that CCC has an adverse effect on a woman's reproductive life as well as a bearing on future generations' health. Filling these knowledge gaps is pivotal for designing more effective disaster and health policies. Policymakers should take into consideration these detrimental effects while designing health schemes and policies for females.
Language	English
Publishing date	2024-01-12
Publishing country	India
Document type	Journal Article ; Review
ZDB-ID	2085330-0
ISSN	1998-3581 ; 0970-0218
ISSN (online)	1998-3581
ISSN	0970-0218
DOI	10.4103/ijcm.ijcm_165_23
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Article ; Online: Interaction of food colorant indigo carmine with human and bovine serum albumins: A multispectroscopic, calorimetric, and theoretical investigation.

Jana, Gouranga / Sing, Shukdeb / Das, Arindam / Basu, Anirban

International journal of biological macromolecules

2024 Volume 259, Issue Pt 1, Page(s) 129143

Abstract: In this work we have studied the interaction of the food dye Indigo-Carmine (IndC) with the most studied model transport proteins i.e. human and bovine serum albumin (HSA & BSA). A multispectroscopic approach was used to analyze the details of the ... ...

Abstract	In this work we have studied the interaction of the food dye Indigo-Carmine (IndC) with the most studied model transport proteins i.e. human and bovine serum albumin (HSA & BSA). A multispectroscopic approach was used to analyze the details of the binding process. The intrinsic fluorescence of both the albumins was significantly quenched by IndC and the quenching was both static and dynamic in nature with the former being dominant. The HSA-lndC and BSA-IndC distance after complexation was determined by Förster resonance energy transfer (FRET) method which suggested efficient energy transfer from the albumins to IndC. Thermodynamics of serum protein-IndC complexation was estimated by isothermal titration calorimetry (ITC) which revealed that the binding was enthalpy driven. Circular dichroism (CD) and FTIR spectroscopy revealed that the binding of IndC induced secondary structural changes in both the serum proteins. Synchronous and 3D fluorescence spectroscopy revealed that the binding interaction caused microenvironmental changes of protein fluorophores. Molecular docking analysis suggested that hydrogen bonding and hydrophobic interactions are the major forces involved in the complexation process.
MeSH term(s)	Humans ; Indigo Carmine ; Molecular Docking Simulation ; Serum Albumin, Bovine/chemistry ; Food Coloring Agents ; Spectrometry, Fluorescence/methods ; Fluorescence Resonance Energy Transfer ; Circular Dichroism ; Thermodynamics ; Calorimetry ; Protein Binding ; Binding Sites
Chemical Substances	Indigo Carmine (D3741U8K7L) ; Serum Albumin, Bovine (27432CM55Q) ; Food Coloring Agents
Language	English
Publishing date	2024-01-03
Publishing country	Netherlands
Document type	Journal Article
ZDB-ID	282732-3
ISSN	1879-0003 ; 0141-8130
ISSN (online)	1879-0003
ISSN	0141-8130
DOI	10.1016/j.ijbiomac.2023.129143
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Article ; Online: Insights into the interaction and inhibitory action of palmatine on lysozyme fibrillogenesis: Spectroscopic and computational studies.

Das, Arindam / Jana, Gouranga / Sing, Shukdeb / Basu, Anirban

International journal of biological macromolecules

2024 Volume 268, Issue Pt 1, Page(s) 131703

Abstract: Interaction under amyloidogenic condition between naturally occurring protoberberine alkaloid palmatine and hen egg white lysozyme was executed by adopting spectrofluorometric and theoretical molecular docking and dynamic simulation analysis. In ... ...

Abstract	Interaction under amyloidogenic condition between naturally occurring protoberberine alkaloid palmatine and hen egg white lysozyme was executed by adopting spectrofluorometric and theoretical molecular docking and dynamic simulation analysis. In spetrofluorometric method, different types of experiments were performed to explore the overall mode and mechanism of interaction. Intrinsic fluorescence quenching of lysozyme (Trp residues) by palmatine showed effective binding interaction and also yielded different binding parameters like binding constant, quenching constant and number of binding sites. Synchronous fluorescence quenching and 3D fluorescence map revealed that palmatine was able to change the microenvironment of the interacting site. Fluorescence life time measurements strongly suggested that this interaction was basically static in nature. Molecular docking result matched with fluorimetric experimental data. Efficient drug like interaction of palmatine with lysozyme at low pH and high salt concentration prompted us to analyze its antifibrillation potential. Different assays and microscopic techniques were employed for detailed analysis of lysozyme amyloidosis.Thioflavin T(ThT) assay, Congo Red (CR) assay, 8-anilino-1-naphthalenesulfonic acid (ANS) assay, Nile Red (NR) assay, anisotropy and intrinsic fluorescence measurements confirmed that palmatine successfully retarded and reduced lysozyme fibrillation. Dynamic light scattering (DLS) and atomic force microscopy (AFM) further reiterated the excellent antiamyloidogenic potency of palmatine.
MeSH term(s)	Muramidase/chemistry ; Muramidase/metabolism ; Berberine Alkaloids/pharmacology ; Berberine Alkaloids/chemistry ; Molecular Docking Simulation ; Protein Binding ; Spectrometry, Fluorescence ; Animals ; Amyloid/chemistry ; Amyloid/metabolism ; Molecular Dynamics Simulation ; Binding Sites ; Hydrogen-Ion Concentration ; Chickens
Chemical Substances	palmatine ; hen egg lysozyme
Language	English
Publishing date	2024-04-21
Publishing country	Netherlands
Document type	Journal Article
ZDB-ID	282732-3
ISSN	1879-0003 ; 0141-8130
ISSN (online)	1879-0003
ISSN	0141-8130
DOI	10.1016/j.ijbiomac.2024.131703
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Article: Menstrual hygiene practices and their determinants among pre-menopausal married women in rural Puducherry.

Parasuraman, Sarala Devi / Das, Arindam

Journal of family medicine and primary care

2022 Volume 11, Issue 7, Page(s) 3795–3800

Abstract: Background: Menstrual hygiene practices are somewhat poor among pre-menstrual aged rural women, and thereby, they are likely to be affected by menstrual and gynaecological morbidities. Hence, an attempt is made to comprehend the magnitude of menstrual ... ...

Abstract	Background: Menstrual hygiene practices are somewhat poor among pre-menstrual aged rural women, and thereby, they are likely to be affected by menstrual and gynaecological morbidities. Hence, an attempt is made to comprehend the magnitude of menstrual hygiene practices through an index among rural women and identify its principal determinants. Methods: Adopting a community-based cross-sectional study design, the required data was collected (through a semi-structured interview schedule) from 780 married pre-menopausal women (aged 35-49 years) from 30 villages of the Puducherry district during January-April 2021. Descriptive and inferential statistics and multiple linear regression techniques were employed. Results: 56% of the present study respondents have exhibited good menstrual hygienic practices (pooled scores 9-15; Median score = 9). Findings from the multiple linear regression model revealed that women's education (β = 0.235; Conclusions: Overall, menstrual hygiene practices among women are moderately high among better socio-economic status. Efforts may be taken to improve the socio-economic conditions and propagate the correct menstrual hygienic practices among rural women, which may enhance hygiene practices during menstruation.
Language	English
Publishing date	2022-07-22
Publishing country	India
Document type	Journal Article
ZDB-ID	2735275-4
ISSN	2278-7135 ; 2249-4863
ISSN (online)	2278-7135
ISSN	2249-4863
DOI	10.4103/jfmpc.jfmpc_2306_21
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Article ; Online: Automated radiosynthesis of mGluR5 PET tracer [

Jahan, Mahabuba / Amir, Arsalan / Das, Arindam / Kihlström, Jacob / Nag, Sangram

Journal of labelled compounds & radiopharmaceuticals

2024 Volume 67, Issue 4, Page(s) 155–164

Abstract: The radioligand [ ...

Abstract	The radioligand [
MeSH term(s)	Pyridines ; Nitriles ; Radiopharmaceuticals ; Positron-Emission Tomography/methods ; Radiochemistry
Chemical Substances	Pyridines ; Nitriles ; Radiopharmaceuticals
Language	English
Publishing date	2024-02-19
Publishing country	England
Document type	Journal Article
ZDB-ID	196095-7
ISSN	1099-1344 ; 0362-4803 ; 0022-2135
ISSN (online)	1099-1344
ISSN	0362-4803 ; 0022-2135
DOI	10.1002/jlcr.4088
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Article ; Online: Design of a Liquid Impregnated Surface with a Stable Lubricant Layer in a Mixed Water/Oil Environment for Low Hydrate Adhesion.

Mund, Abhishek / Nayse, Amit K / Das, Arindam

Langmuir : the ACS journal of surfaces and colloids

2023 Volume 39, Issue 34, Page(s) 11964–11974

Abstract: Clathrate hydrate is a naturally occurring icelike solid that forms in the water phase under suitable temperature and pressure conditions in the presence of one or more hydrophobic molecules. It also forms inside the oil and gas pipes, leading to higher ... ...

Abstract	Clathrate hydrate is a naturally occurring icelike solid that forms in the water phase under suitable temperature and pressure conditions in the presence of one or more hydrophobic molecules. It also forms inside the oil and gas pipes, leading to higher pumping cost, flow blockage, and even catastrophic accidents. Engineered surfaces with low hydrate adhesion can provide an effective solution to this problem. Liquid impregnated surfaces are examples of engineered surfaces that have already shown tremendous potential for reducing the nucleation and adhesion of solids. Here, we report the design and synthesis of liquid impregnated surfaces with extremely low hydrate adhesion under an oil and water mixed environment. The most challenging aspect of designing these surfaces was to stabilize a lubricant layer simultaneously under water and oil. A detailed methodology to make such lubricant-stable surfaces from a theoretical perspective was described and experimentally validated for lubricant stability. Experimental measurements on such surfaces showed extremely low hydrate accumulation and 1 order of magnitude or more reduction in hydrate adhesion force.
Language	English
Publishing date	2023-07-11
Publishing country	United States
Document type	Journal Article
ZDB-ID	2005937-1
ISSN	1520-5827 ; 0743-7463
ISSN (online)	1520-5827
ISSN	0743-7463
DOI	10.1021/acs.langmuir.3c00320
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Article: Relationship Between Vitamin D Deficiency and Non-alcoholic Fatty Liver Disease: A Cross-Sectional Study From a Tertiary Care Center in Northern India.

Kumar, Manoj / Parchani, Ashwin / Kant, Ravi / Das, Arindam

Cureus

2023 Volume 15, Issue 2, Page(s) e34921

Abstract: Background Vitamin D levels are strongly associated with myocardial infarction, coronary artery disease, heart dysfunction, and even mortality. Non-alcoholic fatty liver disease (NAFLD) is a prevalent hepatic illness whose incidence has grown ... ...

Abstract	Background Vitamin D levels are strongly associated with myocardial infarction, coronary artery disease, heart dysfunction, and even mortality. Non-alcoholic fatty liver disease (NAFLD) is a prevalent hepatic illness whose incidence has grown dramatically over the past several decades. Methodology This observational, cross-sectional study was conducted over 1.5 years (January 2019 to June 2020) at the Department of General Medicine of a tertiary care hospital in northern India on 100 adult patients with NAFLD admitted to the emergency ward, intensive care unit, and medical ward. Results In our study, of the 100 patients, 45.0%, 16.0%, and 39.0% of patients exhibited vitamin D deficiency, insufficiency, and sufficiency, respectively. Vitamin D deficiency was the highest among those aged 41-50 (54.2%) and lowest among those aged 30-40 (29.0%). We observed that vitamin D deficiency was less prevalent in people with a normal body mass index (39.1%) than in those who were overweight (91.7%). There was a significant (p < 0.05) association between the severity of vitamin D deficiency and the presence of hepatomegaly, splenomegaly, and ascites. Overall, the incidence of fatty liver was 49% among patients. There was a significant (p = 0.0001) correlation between fatty liver and serum vitamin D levels. The association between the proportion of patients with fatty liver and the degree of vitamin D deficiency was found to be significant (p = 0.04). The relationship between the distribution of patients according to insulin resistance and the degree of vitamin D deficiency was also statistically significant (p < 0.001). Conclusions Vitamin D deficiency is associated with an increased risk of NAFLD, as well as with the severity of NAFLD.
Language	English
Publishing date	2023-02-13
Publishing country	United States
Document type	Journal Article
ZDB-ID	2747273-5
ISSN	2168-8184
ISSN	2168-8184
DOI	10.7759/cureus.34921
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Book ; Online: SoildNet

Das, Arindam

Soiling Degradation Detection in Autonomous Driving

2019

Abstract: In the field of autonomous driving, camera sensors are extremely prone to soiling because they are located outside of the car and interact with environmental sources of soiling such as rain drops, snow, dust, sand, mud and so on. This can lead to either ... ...

Abstract	In the field of autonomous driving, camera sensors are extremely prone to soiling because they are located outside of the car and interact with environmental sources of soiling such as rain drops, snow, dust, sand, mud and so on. This can lead to either partial or complete vision degradation. Hence detecting such decay in vision is very important for safety and overall to preserve the functionality of the "autonomous" components in autonomous driving. The contribution of this work involves: 1) Designing a Deep Convolutional Neural Network (DCNN) based baseline network, 2) Exploiting several network remodelling techniques such as employing static and dynamic group convolution, channel reordering to compress the baseline architecture and make it suitable for low power embedded systems with nearly 1 TOPS, 3) Comparing various result metrics of all interim networks dedicated for soiling degradation detection at tile level of size 64 x 64 on input resolution 1280 x 768. The compressed network, is called SoildNet (Sand, snOw, raIn/dIrt, oiL, Dust/muD) that uses only 9.72% trainable parameters of the base network and reduces the model size by more than 7 times with no loss in accuracy Comment: Accepted at the NeurIPS 2019 Workshop on Machine Learning for Autonomous Driving
Keywords	Computer Science - Computer Vision and Pattern Recognition ; Computer Science - Machine Learning ; Computer Science - Robotics ; Electrical Engineering and Systems Science - Image and Video Processing
Subject code	006
Publishing date	2019-11-04
Publishing country	us
Document type	Book ; Online
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Article ; Online: Endoscopic vs microscopic facial nerve decompression for traumatic facial nerve palsy: a randomized controlled trial.

Das, Arindam / Janweja, Mridul / Mitra, Sandipta / Hazra, Sayan / Sengupta, Arunabha

European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery

2023 Volume 280, Issue 7, Page(s) 3187–3194

Abstract: Purpose: To explore a minimally invasive trans-canal endoscopic facial nerve decompression for traumatic facial nerve palsy and compare it with microscopic facial nerve decompression.: Methods: 35 and 38 patients underwent endoscopic and microscopic ... ...

Abstract	Purpose: To explore a minimally invasive trans-canal endoscopic facial nerve decompression for traumatic facial nerve palsy and compare it with microscopic facial nerve decompression. Methods: 35 and 38 patients underwent endoscopic and microscopic facial nerve decompression, respectively, for traumatic facial nerve palsy. Onset of symptoms, type of temporal bone fracture, day of surgical intervention following trauma, ossicular chain status and nature of insult to facial nerve were observed. Time period for recovery (House Brackmann grade ≤ 3), long term recovery rates, pre- and post-operative hearing status, surgical time and post-operative pain were compared between groups. Results: Maximum patients in endoscopic and microscopic groups (77.1% and 76.3%, respectively) had acute onset of symptoms. 57.1% (20/35) had longitudinal, 17.1% (6/35) had transverse and 25.7% (9/35) had mixed fractures in endoscopic group. In the microscopic group, 57.9% (22/38) had longitudinal, 18.4% (7/38) had transverse and 23.7% (9/38) had mixed fractures. The mean (± S.D.) post-operative air-bone gap in endoscopic and microscopic group were 16.47 ± 4.5 dB and 19.4 ± 5.2 dB, respectively, which was statistically significant. The mean (± S.D.) time period for recovery of endoscopic and microscopic groups were 14.4 ± 5 days and 22.5 ± 7 days, respectively (p value < 0.05). The difference in post-operative pain between the two groups was also statistically significant. The difference in long term recovery rates was not statistically significant (p > 0.05). Conclusions: Endoscopic facial nerve decompression results in early recovery, less post-operative pain and better post-operative air-bone gap closure when compared to conventional microscopic technique.
MeSH term(s)	Humans ; Facial Nerve/surgery ; Facial Paralysis/etiology ; Facial Paralysis/surgery ; Temporal Bone/surgery ; Facial Nerve Injuries/etiology ; Facial Nerve Injuries/surgery ; Fractures, Bone/surgery ; Decompression, Surgical/methods ; Retrospective Studies
Language	English
Publishing date	2023-01-23
Publishing country	Germany
Document type	Randomized Controlled Trial ; Journal Article
ZDB-ID	1017359-6
ISSN	1434-4726 ; 0937-4477
ISSN (online)	1434-4726
ISSN	0937-4477
DOI	10.1007/s00405-023-07836-x
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