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Article ; Online: Significance and Sensor Utility of Phase in Quantum Localization Transition.

Das, Kunal K

2020 Volume 125, Issue 7, Page(s) 70401

Abstract: The degree of localization of the Harper-Hofstadter model is shown to display striking periodic dependence on phase degrees of freedom, which can depend on the nature of the boundary condition, reminiscent of the Aharonov-Bohm effect. In the context of ... ...

Abstract	The degree of localization of the Harper-Hofstadter model is shown to display striking periodic dependence on phase degrees of freedom, which can depend on the nature of the boundary condition, reminiscent of the Aharonov-Bohm effect. In the context of implementation in a finite ring-shaped lattice structure, this phase dependence can be utilized as a fundamentally different principle for precision sensing of rotation and magnetic fields based on localization rather than on interferometry.
Language	English
Publishing date	2020-06-29
Publishing country	United States
Document type	Journal Article
ZDB-ID	208853-8
ISSN	1079-7114 ; 0031-9007
ISSN (online)	1079-7114
ISSN	0031-9007
DOI	10.1103/PhysRevLett.125.070401
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Article ; Online: Cesium immobilization of high pH and low pH belite-rich cement under varying temperature.

Sharma, Raju / Das, Kunal Krishna / Siddique, Salman / Jang, Jeong Gook

Journal of hazardous materials

2024 Volume 469, Page(s) 133995

Abstract: Low-pH cement is being studied in radioactive waste repositories. The belite-rich cement (BRC) recently gained attention due to its higher ... ...

Abstract	Low-pH cement is being studied in radioactive waste repositories. The belite-rich cement (BRC) recently gained attention due to its higher CO
Language	English
Publishing date	2024-03-08
Publishing country	Netherlands
Document type	Journal Article
ZDB-ID	1491302-1
ISSN	1873-3336 ; 0304-3894
ISSN (online)	1873-3336
ISSN	0304-3894
DOI	10.1016/j.jhazmat.2024.133995
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Article: A Cross-Sectional Study of the Haematological Profile of Patients With Chronic Liver Disease (CLD).

Joshi, Deepika / Akram, Mohamad / Das, Kunal / Kala, Mansi

Cureus

2023 Volume 15, Issue 6, Page(s) e40003

Abstract: The liver keeps haematological parameters normal and preserves haemostasis by storing iron, vitamin B-12, and, folic acid, necessary for healthy haematopoiesis. Anaemia of various aetiologies affects approximately 75% of chronic liver disease (CLD) ... ...

Abstract	The liver keeps haematological parameters normal and preserves haemostasis by storing iron, vitamin B-12, and, folic acid, necessary for healthy haematopoiesis. Anaemia of various aetiologies affects approximately 75% of chronic liver disease (CLD) patients, specifically caused by iron deficiency, hypersplenism, chronic diseases, autoimmune haemolysis, folic acid deficiency, aplasticity, and as a side effect of antiviral drugs. This study sought to observe the derangements in haematological parameters in patients with CLD, analyse the spectrum of anaemia in patients with CLD, and predict CLD outcomes utilizing Child-Pugh Score. This cross-sectional observational research was carried out in the Department of General Medicine, Himalayan Institute of Medical Sciences (HIMS), Dehradun, India over the course of a year. The patients with CLD who were admitted to the ward participated in the study. Most patient's blood pictures reported normocytic normochromic with thrombocytopenia (TCP) (28.7%), macrocytic hypochromic with TCP (26%), microcytic hypochromic with TCP (13.3%) and macrocytic normochromic with TCP (9.3%). The incidence of anaemia was 85.3%: mild in 12.7% patients, moderate in 55.3% patients, and severe in 17.3% patients. Interestingly, this study also builds upon others suggesting that 85.9% of CLD patients have Class C Child-Pugh Score.
Language	English
Publishing date	2023-06-05
Publishing country	United States
Document type	Journal Article
ZDB-ID	2747273-5
ISSN	2168-8184
ISSN	2168-8184
DOI	10.7759/cureus.40003
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Article ; Online: Ethical issues facing hematopoietic stem cell transplantation in India.

Raturi, Manish / Das, Kunal

Bulletin du cancer

2021 Volume 108, Issue 10, Page(s) 893–894

Abstract: A successful Hematopoietic stem cell transplantation (HSCT) is often the only hope of survival for children suffering from a range of potentially life-threatening hematological malignancies. The financial, ethical, and emotional problems faced by the ... ...

Abstract	A successful Hematopoietic stem cell transplantation (HSCT) is often the only hope of survival for children suffering from a range of potentially life-threatening hematological malignancies. The financial, ethical, and emotional problems faced by the matched sibling donor and their recipient siblings during the HSCT are extremely complex and challenging. Herein, the authors have attempted to pen down these in the configuration of a poem.
MeSH term(s)	Bioethical Issues ; Child ; Ethics Committees ; Hematologic Neoplasms/therapy ; Hematopoietic Stem Cell Transplantation/economics ; Hematopoietic Stem Cell Transplantation/ethics ; Humans ; India ; Informed Consent By Minors ; Poetry as Topic ; Siblings ; Tissue Donors/psychology
Language	English
Publishing date	2021-07-03
Publishing country	France
Document type	Editorial
ZDB-ID	213270-9
ISSN	1769-6917 ; 0007-4551
ISSN (online)	1769-6917
ISSN	0007-4551
DOI	10.1016/j.bulcan.2021.04.018
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Article ; Online: Primary antibiotic resistance of Helicobacter pylori in India over the past two decades: A systematic review.

Dutta, Spriha / Jain, Surbhi / Das, Kunal / Verma, Prashant / Som, Anup / Das, Rajashree

Helicobacter

2024 Volume 29, Issue 1, Page(s) e13057

Abstract: Background: Helicobacter pylori antibiotic resistance has undergone vast changes in the last two decades. No systematic review has been done on the prevalence of antibiotic resistant H. pylori in India in the last two decades. We evaluated the pattern ... ...

Abstract	Background: Helicobacter pylori antibiotic resistance has undergone vast changes in the last two decades. No systematic review has been done on the prevalence of antibiotic resistant H. pylori in India in the last two decades. We evaluated the pattern of resistance rates across various regions of India. Materials and methods: A systematic review of the geographical variations in antibiotic resistance pattern of H. pylori was conducted using PubMed, Google Scholar, Web of Science, Science Direct, etc. for articles published between January 1, 2000 and May 30, 2023. Random effects-model-based Cochran's Q test, I Results: The overall resistance was highest against metronidazole (77.65%) followed by amoxicillin (37.78%), levofloxacin (32.8%), clarithromycin (35.64%), furazolidone (12.03%), and tetracycline (11.63%). 14.7% of the H. pylori isolates were multi-drug resistant. Under meta-analysis of each antibiotic, high heterogeneity levels were observed having I Conclusions: Metronidazole resistance is high in most regions of India except Assam and Mumbai while clarithromycin is found to be ineffective in South India, Gujarat, and Kashmir. As compared to other antibiotics, resistance to amoxicillin is generally low except in certain regions (Hyderabad, Chennai, and the Gangetic belt of North India). Tetracycline and Furazolidone have the least resistance rates and should be part of anti- H. pylori regimens. The resurgence of high single and multidrug resistance to the commonly used drugs suggests the need for newer antibiotics and regular resistance surveillance studies.
MeSH term(s)	Humans ; Metronidazole/pharmacology ; Metronidazole/therapeutic use ; Clarithromycin ; Helicobacter pylori ; Levofloxacin ; Furazolidone ; India/epidemiology ; Helicobacter Infections/drug therapy ; Helicobacter Infections/epidemiology ; Anti-Bacterial Agents/pharmacology ; Anti-Bacterial Agents/therapeutic use ; Amoxicillin ; Tetracycline ; Antibodies ; Drug Resistance, Microbial
Chemical Substances	Metronidazole (140QMO216E) ; Clarithromycin (H1250JIK0A) ; Levofloxacin (6GNT3Y5LMF) ; Furazolidone (5J9CPU3RE0) ; Anti-Bacterial Agents ; Amoxicillin (804826J2HU) ; Tetracycline (F8VB5M810T) ; Antibodies
Language	English
Publishing date	2024-02-28
Publishing country	England
Document type	Systematic Review ; Meta-Analysis ; Journal Article ; Review
ZDB-ID	1330665-0
ISSN	1523-5378 ; 1083-4389
ISSN (online)	1523-5378
ISSN	1083-4389
DOI	10.1111/hel.13057
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Article: Low abundance of healthy bacteria in the gastric microbiota can be a potential biomarker for gastrointestinal diseases: A pilot study.

Arfi, Safiya / Sharma, Prateek / Das, Kunal / Bhaskar, Yogendra / Goel, Isha / Singh, Harpreet / Das, Rajashree

The Indian journal of medical research

2024 Volume 159, Issue 2, Page(s) 254–258

MeSH term(s)	Humans ; Pilot Projects ; Microbiota ; Bacteria/genetics ; Gastrointestinal Diseases/diagnosis ; Biomarkers ; RNA, Ribosomal, 16S
Chemical Substances	Biomarkers ; RNA, Ribosomal, 16S
Language	English
Publishing date	2024-04-04
Publishing country	India
Document type	Journal Article
ZDB-ID	390883-5
ISSN	0971-5916 ; 0019-5340
ISSN	0971-5916 ; 0019-5340
DOI	10.4103/ijmr.ijmr_864_23
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Article ; Online: Manual red cell exchange (RBCXm) in acute sickle cell crisis: A feasible modality in resource limited settings.

Dhiman, Yashaswi / Khatiwada, Basanta / Das, Kunal / Raturi, Manish / Gaur, Dushyant Singh

Transfusion clinique et biologique : journal de la Societe francaise de transfusion sanguine

2024 Volume 31, Issue 2, Page(s) 119–122

MeSH term(s)	Humans ; Resource-Limited Settings ; Anemia, Sickle Cell/therapy ; Erythrocytes ; Hemoglobinopathies
Language	English
Publishing date	2024-01-18
Publishing country	France
Document type	Journal Article
ZDB-ID	1204698-x
ISSN	1953-8022 ; 1246-7820
ISSN (online)	1953-8022
ISSN	1246-7820
DOI	10.1016/j.tracli.2024.01.006
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Article ; Online: Dysbiosis of gut microbiota due to diet, alcohol intake, body mass index, and gastrointestinal diseases in India.

Sharma, Prateek / Singh, Sarika / Das, Kunal / Mahant, Shweta / Das, Rajashree

Applied microbiology and biotechnology

2023 Volume 107, Issue 7-8, Page(s) 2547–2560

Abstract: The human gut is composed of diverse microflora which is influenced by dietary intake. Body mass index (BMI) and lifestyle patterns also play a vital role in human health to alter gut microbial composition. Our study aims to determine the impact of ... ...

Abstract	The human gut is composed of diverse microflora which is influenced by dietary intake. Body mass index (BMI) and lifestyle patterns also play a vital role in human health to alter gut microbial composition. Our study aims to determine the impact of alcohol intake, BMI, and diet on gut microbiota and its relationship with gastrointestinal disorders. Thirty-nine gastric biopsies were taken from patients with various gastrointestinal (GI) diseases, and all the patient's lifestyle behavior were recorded in a written proforma. 16S rRNA metagenome analysis for V3-V4 regions was used to examine microbial compositions. The richness and diversity of gut microbiota were analyzed by PERMANOVA using the Bray-Curtis dissimilarity index and principal component analysis. The difference in relative abundance was calculated by ANOVA (p < 0.05). Alpha diversity indexes between vegetarians and non-vegetarians showed no significant difference based on BMI, alcohol status, and GI diseases. We found that in overweight vegetarian individuals Faecalibacterium and Rumicococcus might play a role in the control of Helicobacter pylori. Similarly, the increased abundance of Akkermansia muciniphila in non-vegetarian individuals with normal BMI might play a role to decrease the level of harmful bacteria like H. pylori, and Corynebacterium sp. Also, the relative abundance of Corynebacterium sp. among the vegetarians and Streptococcus sp. in the non-vegetarians was increased in alcoholics while H. pylori was increased in non-alcoholics irrespective of diet. There is an increased abundance of Faecalibacterium prausnitzii in vegetarians among all categories; however, we did not find any correlation between disease outcomes. Our study shows that alcohol intake and dietary habits have independent effects on gut microbial composition. The relative abundance of F. prausnitzii was high among vegetarians in all categories. KEY POINTS: • The presence of H. pylori is less among alcoholics. • Good bacteria help to maintain a normal body mass index. • Gut microbiota richness is high in vegetarians and diversity in non-vegetarians.
MeSH term(s)	Humans ; Gastrointestinal Microbiome/genetics ; Body Mass Index ; RNA, Ribosomal, 16S/genetics ; Dysbiosis ; Diet ; Bacteria/genetics ; Alcohol Drinking ; Gastrointestinal Diseases
Chemical Substances	RNA, Ribosomal, 16S
Language	English
Publishing date	2023-03-16
Publishing country	Germany
Document type	Journal Article
ZDB-ID	392453-1
ISSN	1432-0614 ; 0171-1741 ; 0175-7598
ISSN (online)	1432-0614
ISSN	0171-1741 ; 0175-7598
DOI	10.1007/s00253-023-12470-y
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Article ; Online: Endorsing a permanent lifting of the ban on men who have sex with men and transgender from donating their whole blood.

Raturi, Manish / Das, Kunal / Dhiman, Yashaswi

Indian journal of sexually transmitted diseases and AIDS

2022 Volume 43, Issue 1, Page(s) 100–102

Language	English
Publishing date	2022-06-07
Publishing country	India
Document type	Journal Article
ZDB-ID	2622183-4
ISSN	2589-0565 ; 2589-0565
ISSN (online)	2589-0565
ISSN	2589-0565
DOI	10.4103/ijstd.ijstd_122_20
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Article ; Online: Dysbiosis of gut microbiota due to diet, alcohol intake, body mass index, and gastrointestinal diseases in India

Sharma, Prateek / Singh, Sarika / Das, Kunal / Mahant, Shweta / Das, Rajashree

Appl Microbiol Biotechnol. 2023 Apr., v. 107, no. 7-8 p.2547-2560

2023

Abstract	The human gut is composed of diverse microflora which is influenced by dietary intake. Body mass index (BMI) and lifestyle patterns also play a vital role in human health to alter gut microbial composition. Our study aims to determine the impact of alcohol intake, BMI, and diet on gut microbiota and its relationship with gastrointestinal disorders. Thirty-nine gastric biopsies were taken from patients with various gastrointestinal (GI) diseases, and all the patient’s lifestyle behavior were recorded in a written proforma. 16S rRNA metagenome analysis for V3-V4 regions was used to examine microbial compositions. The richness and diversity of gut microbiota were analyzed by PERMANOVA using the Bray–Curtis dissimilarity index and principal component analysis. The difference in relative abundance was calculated by ANOVA (p < 0.05). Alpha diversity indexes between vegetarians and non-vegetarians showed no significant difference based on BMI, alcohol status, and GI diseases. We found that in overweight vegetarian individuals Faecalibacterium and Rumicococcus might play a role in the control of Helicobacter pylori. Similarly, the increased abundance of Akkermansia muciniphila in non-vegetarian individuals with normal BMI might play a role to decrease the level of harmful bacteria like H. pylori, and Corynebacterium sp. Also, the relative abundance of Corynebacterium sp. among the vegetarians and Streptococcus sp. in the non-vegetarians was increased in alcoholics while H. pylori was increased in non-alcoholics irrespective of diet. There is an increased abundance of Faecalibacterium prausnitzii in vegetarians among all categories; however, we did not find any correlation between disease outcomes. Our study shows that alcohol intake and dietary habits have independent effects on gut microbial composition. The relative abundance of F. prausnitzii was high among vegetarians in all categories. KEY POINTS: • The presence of H. pylori is less among alcoholics. • Good bacteria help to maintain a normal body mass index. • Gut microbiota richness is high in vegetarians and diversity in non-vegetarians.
Keywords	Corynebacterium ; Helicobacter pylori ; Streptococcus ; alcohol drinking ; alcohols ; body mass index ; dysbiosis ; food intake ; gastrointestinal system ; human health ; humans ; intestinal microorganisms ; lifestyle ; metagenomics ; overweight ; patients ; principal component analysis ; species diversity ; vegetarian diet ; India
Language	English
Dates of publication	2023-04
Size	p. 2547-2560.
Publishing place	Springer Berlin Heidelberg
Document type	Article ; Online
ZDB-ID	392453-1
ISSN	1432-0614 ; 0171-1741 ; 0175-7598
ISSN (online)	1432-0614
ISSN	0171-1741 ; 0175-7598
DOI	10.1007/s00253-023-12470-y
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