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  1. Book ; Online ; E-Book: Fighting the opioid epidemic

    Dasgupta, Amitava

    the role of providers and the clinical laboratory in understanding who is vulnerable

    2020  

    Abstract: Fighting the Opioid Epidemic: The Role of Providers and the Clinical Laboratory in Understanding Who Is Vulnerable covers the important aspects that are essential in fighting the opioid epidemic. This succinct reference highlights how the toxicology ... ...

    Author's details Amitava Dasgupta
    Abstract "Fighting the Opioid Epidemic: The Role of Providers and the Clinical Laboratory in Understanding Who Is Vulnerable covers the important aspects that are essential in fighting the opioid epidemic. This succinct reference highlights how the toxicology laboratory can play a vital role in fighting the opioid epidemic by implementing a robust system for drugs of abuse testing as well as drug testing in pain management patients. It targets health care professionals in a technical manner, discussing polymorphisms of important genes that may be associated with increased vulnerability of alcohol and drug addiction to an individual. Covers all important aspects of opioid abuse, including genetic and environmental factors Discusses pharmacology, toxicology and the pharmacogenomics related to opioid metabolism Presents genetic and environmental factors associated with those vulnerable to opioid addiction, as well as the pitfalls of drug testing in pain management."--
    Keywords Opioid abuse
    Subject code 362.293
    Language English
    Size 1 online resource (ix, 149 pages) :, illustrations
    Publisher Elsevier
    Publishing place Amsterdam, Netherlands ; Oxford, England ; Cambridge, Massachusetts
    Document type Book ; Online ; E-Book
    Remark Zugriff für angemeldete ZB MED-Nutzerinnen und -Nutzer
    ISBN 0-12-822390-1 ; 0-12-820075-8 ; 978-0-12-822390-1 ; 978-0-12-820075-9
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  2. Book ; Online ; E-Book: Biotin and other interferences in immunoassays

    Dasgupta, Amitava

    a concise guide

    2019  

    Author's details Amitava Dasgupta, PHD
    Keywords Biotin ; Immunoassay
    Subject code 572.7
    Language English
    Size 1 Online-Ressource (vii, 136 Seiten), Diagramme
    Publisher Elsevier
    Publishing place St. Louis, Missouri
    Publishing country United States
    Document type Book ; Online ; E-Book
    Remark Zugriff für angemeldete ZB MED-Nutzerinnen und -Nutzer
    HBZ-ID HT019981456
    ISBN 978-0-12-816741-0 ; 9780128164297 ; 0-12-816741-6 ; 0128164298
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  3. Book: Therapeutic drug monitoring data

    Dasgupta, Amitava / Krasowski, Matthew D.

    a concise guide

    2020  

    Author's details Amitava Dasgupta, Matthew Krasowski
    Keywords Drug monitoring
    Subject code 615.7
    Language English
    Size xi, 370 Seiten, Illustrationen, 23 cm
    Edition fourth edition
    Publisher Elsevier
    Publishing place Amsterdam
    Publishing country Netherlands
    Document type Book
    HBZ-ID HT020289727
    ISBN 978-0-12-815849-4 ; 9780128158500 ; 0-12-815849-2 ; 0128158506
    Database Catalogue ZB MED Medicine, Health

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  4. Book: Alcohol and its biomarkers

    Dasgupta, Amitava

    clinical aspects and laboratory determination

    (Clinical aspects and laboratory determination of biomarkers series ; 1)

    2015  

    Author's details Amitava Dasgupta
    Series title Clinical aspects and laboratory determination of biomarkers series ; 1
    Clinical aspects and laboatory determination of biomarkers series
    Collection Clinical aspects and laboatory determination of biomarkers series
    Language English
    Size XII, 300 S. : graph. Darst.
    Publisher Elsevier
    Publishing place Amsterdam u.a.
    Publishing country Netherlands
    Document type Book
    HBZ-ID HT018600452
    ISBN 978-0-12-800339-8 ; 0-12-800339-1
    Database Catalogue ZB MED Medicine, Health

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  5. Article ; Online: Significant Improvement in Digoxin Immunoassays Over Four Decades: Newer Assays are Less Affected by Interferences.

    Dasgupta, Amitava

    Therapeutic drug monitoring

    2023  Volume 45, Issue 1, Page(s) 26–34

    Abstract: Background: Digitalis glycosides derived from foxglove plants have been used for medicinal purposes since the 16th century. Currently, digoxin derived from foxgloves is used clinically. Owing to the narrow therapeutic range, therapeutic drug monitoring ... ...

    Abstract Background: Digitalis glycosides derived from foxglove plants have been used for medicinal purposes since the 16th century. Currently, digoxin derived from foxgloves is used clinically. Owing to the narrow therapeutic range, therapeutic drug monitoring is essential; however, digoxin immunoassays suffer from interference.
    Methods: The issue of interference was reviewed for both older polyclonal antibody-based digoxin assays and newer monoclonal antibody-based digoxin assays. A literature search was conducted using PubMed, ScienceDirect, Scopus, Web of Science, and ResearchGate for studies on digoxin immunoassays published in the English language from 1969 to the present.
    Results: Radioimmunoassays for digoxin in the 1970s and, later, first-generation nonradioimmunoassay methods were liable to several interferences, including digoxin-like immunoreactive substances, spironolactone, potassium canrenoate, and various digoxin metabolites. However, for the last 10-15 years, next next-generation digoxin immunoassays have been virtually free from such interferences. Nevertheless, certain herbal supplements, as well as both Digibind and DigiFab, interfere with serum digoxin measurement, even with the more recently developed digoxin assays.
    Conclusions: More recently introduced monoclonal antibody-based digoxin assays are superior to the older polyclonal antibody-based digoxin assays.
    MeSH term(s) Humans ; Digoxin ; Immunoassay ; Antibodies, Monoclonal ; Biological Assay ; Language
    Chemical Substances Digoxin (73K4184T59) ; Antibodies, Monoclonal
    Language English
    Publishing date 2023-01-06
    Publishing country United States
    Document type Journal Article
    ZDB-ID 424443-6
    ISSN 1536-3694 ; 0163-4356
    ISSN (online) 1536-3694
    ISSN 0163-4356
    DOI 10.1097/FTD.0000000000001005
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Immunoassay design and biotin interference.

    Dasgupta, Amitava

    Advances in clinical chemistry

    2022  Volume 109, Page(s) 165–183

    Abstract: Biotin (vitamin ... ...

    Abstract Biotin (vitamin B
    MeSH term(s) Biotin/chemistry ; Diagnostic Errors ; Humans ; Immunoassay ; Thyroid Function Tests
    Chemical Substances Biotin (6SO6U10H04)
    Language English
    Publishing date 2022-05-05
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 210505-6
    ISSN 2162-9471 ; 0065-2423
    ISSN (online) 2162-9471
    ISSN 0065-2423
    DOI 10.1016/bs.acc.2022.03.005
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Book: Resolving erroneous reports in toxicology and therapeutic drug monitoring

    Dasgupta, Amitava

    a comprehensive guide

    2012  

    Author's details Amitava Dasgupta
    Keywords Drug Monitoring / methods ; Substance Abuse Detection / methods ; False Positive Reactions ; Pharmaceutical Preparations / analysis ; Drug monitoring ; Toxicity testing
    Language English
    Size VIII, 457 S. : graph. Darst., 28 cm
    Publisher Wiley
    Publishing place Hoboken, NJ
    Publishing country United States
    Document type Book
    Note Includes bibliographical references
    HBZ-ID HT017374745
    ISBN 978-1-118-14965-2 ; 1-118-14965-3
    Database Catalogue ZB MED Medicine, Health

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  8. Book: Effects of herbal supplements in medicine

    Dasgupta, Amitava

    (Patient safety ; 2)

    2011  

    Title variant Effects of herbal supplements on clinical laboratory test results
    Author's details Amitava Dasgupta
    Series title Patient safety ; 2
    Collection
    Keywords Plant Preparations / adverse effects ; Dietary Supplements / adverse effects ; Clinical Chemistry Tests ; Nahrungsergänzungsmittel ; Pflanzeninhaltsstoff ; Toxizität ; Klinische Chemie
    Subject Giftigkeit ; Toxische Wirkung ; Pflanzen ; Pflanzenstoff ; Sekundärer Pflanzenstoff ; Pflanzlicher Inhaltsstoff ; Phytochemikalie ; Pflanzenwirkstoff ; Sekundärer Pflanzeninhaltsstoff ; Nutraceutical ; Nutraceuticals ; Nutriceutical
    Language English
    Size XI, 122 S. : Ill., 240 mm x 170 mm
    Publisher De Gruyter
    Publishing place Berlin u.a.
    Publishing country Germany
    Document type Book
    Note Hauptsacht. auf dem Umschlag: Effects of herbal supplements on clinical laboratory test results
    HBZ-ID HT016832690
    ISBN 978-3-11-024561-5 ; 3-11-024561-2
    Database Catalogue ZB MED Medicine, Health

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  9. Book: Beating drug tests and defending positive results

    Dasgupta, Amitava

    a toxicologist's perspective

    2010  

    Author's details Amitava Dasgupta
    Keywords Substance Abuse Detection / methods ; Drug and Narcotic Control / methods ; Street Drugs / analysis ; Workplace
    Language English
    Size XIII, 152 S. : Ill., 24 cm
    Publisher Springer ; Humana Pr
    Publishing place New York u.a. ; Totowa, NJ
    Publishing country United States
    Document type Book
    Note Includes bibliographical references and index
    HBZ-ID HT017024729
    ISBN 978-1-60761-526-2 ; 1-60761-526-6 ; 978-1-607-61527-9 ; 1-607-61527-4
    Database Catalogue ZB MED Medicine, Health

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  10. Article: Severe jaundice with life-threatening liver failure after Kratom use: Reversed by plasma exchange.

    Dasgupta, Amitava / Ye, Zhan

    Transfusion and apheresis science : official journal of the World Apheresis Association : official journal of the European Society for Haemapheresis

    2024  , Page(s) 103898

    Abstract: Kratom is an herbal supplement which is used for its stimulating properties and pain reduction due to interaction with opioid receptors. Kratom overdose may cause fatality. A 56-year-old man was admitted to the emergency department with severe jaundice ... ...

    Abstract Kratom is an herbal supplement which is used for its stimulating properties and pain reduction due to interaction with opioid receptors. Kratom overdose may cause fatality. A 56-year-old man was admitted to the emergency department with severe jaundice and liver failure. His total bilirubin reached at 70.6 mg/dL, but extensive workup did not show any liver mass. Family informed that the patient was taking Kratom. Plasma exchange was suggested as an unconventional therapy and consent from the patient was obtained because this procedure has never been performed to treat Kratom toxicity before. After four procedures, his total bilirubin was reduced to 23.9 mg/dL and his clinical condition improved significantly. Finally on day 5 he was discharged at stable condition with a total bilirubin value of 21.3 mg/dL. There is no antidote for Kratom, and treatment is supportive. To our knowledge this is the first report of reversing Kratom poisoning using plasma exchange.
    Language English
    Publishing date 2024-02-08
    Publishing country England
    Document type Journal Article
    ZDB-ID 2046795-3
    ISSN 1878-1683 ; 1473-0502
    ISSN (online) 1878-1683
    ISSN 1473-0502
    DOI 10.1016/j.transci.2024.103898
    Database MEDical Literature Analysis and Retrieval System OnLINE

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