LIVIVO - The Search Portal for Life Sciences

zur deutschen Oberfläche wechseln
Advanced search

Search results

Result 1 - 10 of total 29

Search options

  1. Book: Valeur primordiale de l'échographie en aval de la mammographie de dépistage du cancer du sein

    David, Pascal

    (Le sein ; 14, Hors sér. 1)

    2004  

    Author's details par Pascal David
    Series title Le sein ; 14, Hors sér. 1
    Collection
    Language French
    Size 18 S. : Ill.
    Publisher Masson
    Publishing place Paris
    Publishing country France
    Document type Book
    HBZ-ID HT014195850
    Database Catalogue ZB MED Medicine, Health

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    Zs A 4680 -14,HorsSér.1- not available for loan Zeitschriften-Lesesaal

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  2. Book ; Online ; Thesis: Longitudinale Veränderungen der retinalen Pathologie bei idiopathischem Parkinsonsyndrom

    Batra, David Pascal [Verfasser]

    2023  

    Author's details David Batra
    Keywords Medizin, Gesundheit ; Medicine, Health
    Subject code sg610
    Language German
    Publisher Universität Ulm
    Publishing place Ulm
    Document type Book ; Online ; Thesis
    Database Digital theses on the web

    Full text online

    More links

    Kategorien

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  3. Article ; Online: Prediction and experimental evidence of different growth phases of the Podospora anserina hyphal network.

    Ledoux, Clara / Chapeland-Leclerc, Florence / Ruprich-Robert, Gwenaël / Bobée, Cécilia / Lalanne, Christophe / Herbert, Éric / David, Pascal

    Scientific reports

    2023  Volume 13, Issue 1, Page(s) 8501

    Abstract: Under ideal conditions, the growth of the mycelial network of a filamentous fungus is monotonous, showing an ever increasing complexity with time. The components of the network growth are very simple and based on two mechanisms: the elongation of each ... ...

    Abstract Under ideal conditions, the growth of the mycelial network of a filamentous fungus is monotonous, showing an ever increasing complexity with time. The components of the network growth are very simple and based on two mechanisms: the elongation of each hypha, and their multiplication by successive branching. These two mechanisms are sufficient to produce a complex network, and could be localized only at the tips of hyphae. However, branching can be of two types, apical or lateral, depending on its location on the hyphae, therefore imposing the redistribution of the necessary material in the whole mycelium. From an evolutionary point of view, maintaining different branching processes, with additional energy needs for structure and metabolism, is intriguing. We propose in this work to discuss the advantages of each branching type using a new observable for the network growth, allowing us to compare growth configurations. For this purpose, we build on experimental observations of the Podospora anserina mycelium growth, enabling us to feed and constrain a lattice-free modeling of this network based on a binary tree. First, we report the set of statistics related to the branches of P. anserina that we have implemented into the model. Then, we build the density observable, allowing us to discuss the succession of growth phases. We predict that density over time is not monotonic, but shows a decay growth phase, clearly separated from an other one by a stationary phase. The time of appearance of this stable region appears to be driven solely by the growth rate. Finally, we show that density is an appropriate observable to differentiate growth stress.
    MeSH term(s) Hyphae ; Podospora ; Mycelium ; Fungi/metabolism ; Fungal Proteins/metabolism
    Chemical Substances Fungal Proteins
    Language English
    Publishing date 2023-05-25
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2615211-3
    ISSN 2045-2322 ; 2045-2322
    ISSN (online) 2045-2322
    ISSN 2045-2322
    DOI 10.1038/s41598-023-35327-w
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  4. Article ; Online: Characterization of spatio-temporal dynamics of the constrained network of the filamentous fungus Podospora anserina using a geomatics-based approach.

    Ledoux, Clara / Bobée, Cécilia / Cabet, Éva / David, Pascal / Filaine, Frédéric / Hachimi, Sabrina / Lalanne, Christophe / Ruprich-Robert, Gwenaël / Herbert, Éric / Chapeland-Leclerc, Florence

    PloS one

    2024  Volume 19, Issue 2, Page(s) e0297816

    Abstract: In their natural environment, fungi are subjected to a wide variety of environmental stresses which they must cope with by constantly adapting the architecture of their growing network. In this work, our objective was to finely characterize the thallus ... ...

    Abstract In their natural environment, fungi are subjected to a wide variety of environmental stresses which they must cope with by constantly adapting the architecture of their growing network. In this work, our objective was to finely characterize the thallus development of the filamentous fungus Podospora anserina subjected to different constraints that are simple to implement in vitro and that can be considered as relevant environmental stresses, such as a nutrient-poor environment or non-optimal temperatures. At the Petri dish scale, the observations showed that the fungal thallus is differentially affected (thallus diameter, mycelium aspect) according to the stresses but these observations remain qualitative. At the hyphal scale, we showed that the extraction of the usual quantities (i.e. apex, node, length) does not allow to distinguish the different thallus under stress, these quantities being globally affected by the application of a stress in comparison with a thallus having grown under optimal conditions. Thanks to an original geomatics-based approach based on the use of automatized Geographic Information System (GIS) tools, we were able to produce maps and metrics characterizing the growth dynamics of the networks and then to highlight some very different dynamics of network densification according to the applied stresses. The fungal thallus is then considered as a map and we are no longer interested in the quantity of material (hyphae) produced but in the empty spaces between the hyphae, the intra-thallus surfaces. This study contributes to a better understanding of how filamentous fungi adapt the growth and densification of their network to potentially adverse environmental changes.
    MeSH term(s) Podospora ; Fungi ; Hyphae ; Mycelium ; Stress, Physiological ; Fungal Proteins
    Chemical Substances Fungal Proteins
    Language English
    Publishing date 2024-02-06
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2267670-3
    ISSN 1932-6203 ; 1932-6203
    ISSN (online) 1932-6203
    ISSN 1932-6203
    DOI 10.1371/journal.pone.0297816
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  5. Article ; Online: Prediction and experimental evidence of the optimisation of the angular branching process in the thallus growth of Podospora anserina.

    Ledoux, Clara / Chapeland-Leclerc, Florence / Ruprich-Robert, Gwenaël / Bobée, Cécilia / Lalanne, Christophe / Herbert, Éric / David, Pascal

    Scientific reports

    2022  Volume 12, Issue 1, Page(s) 12351

    Abstract: Based upon apical growth and hyphal branching, the two main processes that drive the growth pattern of a fungal network, we propose here a two-dimensions simulation based on a binary-tree modelling allowing us to extract the main characteristics of a ... ...

    Abstract Based upon apical growth and hyphal branching, the two main processes that drive the growth pattern of a fungal network, we propose here a two-dimensions simulation based on a binary-tree modelling allowing us to extract the main characteristics of a generic thallus growth. In particular, we showed that, in a homogeneous environment, the fungal growth can be optimized for exploration and exploitation of its surroundings with a specific angular distribution of apical branching. Two complementary methods of extracting angle values have been used to confront the result of the simulation with experimental data obtained from the thallus growth of the saprophytic filamentous fungus Podospora anserina. Finally, we propose here a validated model that, while being computationally low-cost, is powerful enough to test quickly multiple conditions and constraints. It will allow in future works to deepen the characterization of the growth dynamic of fungal network, in addition to laboratory experiments, that could be sometimes expensive, tedious or of limited scope.
    MeSH term(s) Fungal Proteins ; Fungi ; Hyphae ; Podospora
    Chemical Substances Fungal Proteins
    Language English
    Publishing date 2022-07-19
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2615211-3
    ISSN 2045-2322 ; 2045-2322
    ISSN (online) 2045-2322
    ISSN 2045-2322
    DOI 10.1038/s41598-022-16245-9
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  6. Article ; Online: Core level shifts as indicators of Cr chemistry on hydroxylated α-Al

    Messaykeh, Maya / Chenot, Stéphane / David, Pascal / Cabailh, Gregory / Jupille, Jacques / Koltsov, Alexey / Lagarde, Pierre / Trcera, Nicolas / Goniakowski, Jacek / Lazzari, Rémi

    Physical chemistry chemical physics : PCCP

    2021  Volume 23, Issue 38, Page(s) 21852–21862

    Abstract: ... The Cr/α- ... ...

    Abstract The Cr/α-Al
    Language English
    Publishing date 2021-10-06
    Publishing country England
    Document type Journal Article
    ZDB-ID 1476244-4
    ISSN 1463-9084 ; 1463-9076
    ISSN (online) 1463-9084
    ISSN 1463-9076
    DOI 10.1039/d1cp03224k
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  7. Book: La finalité de la recherche biomédicale

    Boles, Jean-Michel / David, Pascal

    vers un arraisonnement de l'être humain ? : [Actes du colloque co-organisé par l'Espace éthique de Bretagne occidentale et l'Espace de réflexion éthique de Saint Brieuc, Brest, 10-12 décembre 2008]

    (Carnets de l'Espace éthique de Bretagne occidentale ; no. 3)

    2010  

    Author's details sous la direction de Jean-Michel Boles, Pascal David
    Series title Carnets de l'Espace éthique de Bretagne occidentale ; no. 3
    MeSH term(s) Biomedical Research/ethics
    Language French
    Size 322 p.
    Publisher Sauramps médical
    Publishing place Montpellier
    Document type Book
    ISBN 9782840237143 ; 2840237148
    Database Catalogue of the US National Library of Medicine (NLM)

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  8. Article ; Online: Gait Monitoring and Walk Distance Estimation With an Accelerometer During 6-Minute Walk Test.

    Retory, Yann / David, Pascal / Niedzialkowski, Pauline / de Picciotto, Carole / Bonay, Marcel / Petitjean, Michel

    Respiratory care

    2019  Volume 64, Issue 8, Page(s) 923–930

    Abstract: Background: The 6-min walk test (6MWT) encompasses potential and untapped information related to exercise capacity. However, this test does not yield any information about gait pattern. Recently, we used a ventilatory polygraph to reveal respiratory ... ...

    Abstract Background: The 6-min walk test (6MWT) encompasses potential and untapped information related to exercise capacity. However, this test does not yield any information about gait pattern. Recently, we used a ventilatory polygraph to reveal respiratory adaptation during the 6MWT with subjects having high or low body mass index (BMI). In this study, we aimed to determine gait parameters with the same device, which integrates an accelerometer.
    Methods: Using a 30-m corridor, steps and U-turns were detected with a custom-made algorithm, compared to video recordings as a reference method, and analyzed offline. From the vertical acceleration signal, we were able to determine cadence and step length, and we could calculate the total distance covered in 6 min (6MWD). We then compared these variables between subjects with low BMI (
    Results: Steps and U-turn detection correlated with video results (
    Conclusion: Our results demonstrated that a ventilatory polygraph with an embedded accelerometer can be used to detect steps and U-turns, and to calculate 6MWD. This method is sufficiently sensitive to characterize significant BMI-dependent differences in gait pattern during a 6MWT and appears to be a promising tool for routine clinical use.
    MeSH term(s) Accelerometry/instrumentation ; Accelerometry/methods ; Adult ; Body Mass Index ; Female ; Gait Analysis/methods ; Humans ; Male ; Middle Aged ; Overweight/physiopathology ; Walk Test/methods ; Walking/statistics & numerical data
    Language English
    Publishing date 2019-06-18
    Publishing country United States
    Document type Journal Article
    ZDB-ID 603252-7
    ISSN 1943-3654 ; 0098-9142 ; 0020-1324
    ISSN (online) 1943-3654
    ISSN 0098-9142 ; 0020-1324
    DOI 10.4187/respcare.06144
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.B 2285: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  9. Book ; Online: Prediction and experimental evidence of the optimisation of the angular branching process in the thallus growth of Podospora anserina

    Ledoux, Clara / Chapeland-Leclerc, Florence / Ruprich-Robert, Gwenaël / Bobée, Cécilia / Lalanne, Christophe / Herbert, Éric / David, Pascal

    2022  

    Abstract: Based upon apical growth and hyphal branching, the two main processes that drive the growth pattern of a fungal network, we propose here a two-dimensions simulation based on a binary-tree modelling allowing us to extract the main characteristics of a ... ...

    Abstract Based upon apical growth and hyphal branching, the two main processes that drive the growth pattern of a fungal network, we propose here a two-dimensions simulation based on a binary-tree modelling allowing us to extract the main characteristics of a generic thallus growth. In particular, we showed that, in a homogeneous environment, the fungal growth can be optimized for exploration and exploitation of its surroundings with a specific angular distribution of apical branching. Two complementary methods of extracting angle values have been used to confront the result of the simulation with experimental data obtained from the thallus growth of the saprophytic filamentous fungus Podospora anserina. Finally, we propose here a validated model that, while being computationally low-cost, is powerful enough to test quickly multiple conditions and constraints. It will allow in future works to deepen the characterization of the growth dynamic of fungal network, in addition to laboratory experiments, that could be sometimes expensive, tedious or of limited scope.

    Comment: Submitted to Scientific Report
    Keywords Quantitative Biology - Quantitative Methods
    Subject code 612
    Publishing date 2022-06-10
    Publishing country us
    Document type Book ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    Full text online

    More links

    Kategorien

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  10. Article ; Online: Postural- and respiratory-related activities of abdominal muscles during post-exercise hyperventilation.

    David, Pascal / Terrien, Jérémy / Petitjean, Michel

    Gait & posture

    2015  Volume 41, Issue 4, Page(s) 899–904

    Abstract: The present study focuses on the role of superficial abdominal muscles revealed by electromyographic recordings during the maintenance of a bipedal stance perturbed by post-exercise hyperventilation. Twelve healthy subjects performed six 30-s postural ... ...

    Abstract The present study focuses on the role of superficial abdominal muscles revealed by electromyographic recordings during the maintenance of a bipedal stance perturbed by post-exercise hyperventilation. Twelve healthy subjects performed six 30-s postural tests: one pre-exercise test while breathing quietly, then one test every minute for the 5 min immediately following a maximum-intensity, incremental cycling exercise test. Displacement of the centre of pressure in the sagittal plane was monitored over time. Myoelectric activities of the obliquus externus (OE), obliquus internus (OI) and rectus abdominis (RA) muscles were recorded by surface electromyography (EMG). Metabolic parameters were measured with a portable telemetric device. The change in ventilatory drive induced by exercise was accompanied by a significant increase in both postural sway parameters and EMG activities. For OE and OI, the increased EMG activities were prominent during expiration, whereas OI was silent during inspiration. OE and RA were activated during both expiration and inspiration. It is concluded that the compensation of respiratory disturbances of the erect posture appears to be less effective when minute ventilation increases. The patterns of muscle activity suggest that abdominal muscles are controlled differentially and that their functional coordination is dependent on the respiratory demand.
    MeSH term(s) Electromyography ; Exercise/physiology ; Exercise Test ; Female ; Healthy Volunteers ; Humans ; Hyperventilation/physiopathology ; Male ; Posture/physiology ; Rectus Abdominis/physiopathology ; Respiration ; Young Adult
    Language English
    Publishing date 2015-05
    Publishing country England
    Document type Journal Article
    ZDB-ID 1162323-8
    ISSN 1879-2219 ; 0966-6362
    ISSN (online) 1879-2219
    ISSN 0966-6362
    DOI 10.1016/j.gaitpost.2015.03.012
    Database MEDical Literature Analysis and Retrieval System OnLINE

    Full text online

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 3804: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

To top