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  1. Book ; Conference proceedings: Bone engineering

    Davies, John E.

    [based on the proceedings of the Bone Engineering Workshop, held in Toronto, Ontario, December 2 - 3, 1999]

    2000  

    Institution Bone Engineering Workshop
    Author's details ed. by J. E. Davies
    Keywords Implantatwerkstoff ; Knochen
    Subject Bone ; Bones ; Os ; Knochengewebe
    Language English
    Size XIV, 656 S. : Ill. graph. Darst.
    Publisher EM Squared
    Publishing place Toronto
    Publishing country Canada
    Document type Book ; Conference proceedings
    HBZ-ID HT012938840
    ISBN 0-9686980-0-X ; 978-0-9686980-0-6
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    2002 A 4787 order for loan Magazin

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  2. Book ; Article ; Online: Los plaguicidas y el ambiente Cambios en el efecto de los plaguicidas sobre la salud del hombre

    Davies, J. E

    2015  

    Keywords Poluição Ambiental ; Praguicidas
    Publishing date 2015-12-08T02:50:06Z
    Document type Book ; Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  3. Book ; Conference proceedings: The bone biomaterial interface

    Davies, John E.

    [based on the proceedings of the Bone Biomaterial Interface Workshop held in Toronto, Ont., Dec. 3 - 4, 1990]

    1991  

    Title variant bone biomaterial
    Event/congress Bone Biomaterial Interface Workshop (1990, Toronto)
    Author's details ed. by J. E. Davies
    Keywords Biocompatible Materials / congresses ; Prostheses and Implants / congresses ; Bone and Bones / surgery / congresses ; Biomaterial ; Knochen
    Subject Bone ; Bones ; Os ; Knochengewebe ; Biomedizinisches Material
    Size XIV, 502 S. : Ill., graph. Darst.
    Publisher Univ. of Toronto Press
    Publishing place Toronto u.a.
    Publishing country Canada
    Document type Book ; Conference proceedings
    HBZ-ID HT004242510
    ISBN 0-8020-5941-4 ; 978-0-8020-5941-3
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    1992 A 3635 order for loan Magazin

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  4. Article: Recent developments in renal denervation.

    Raphael, C E / Davies, J E

    Minerva cardioangiologica

    2013  Volume 61, Issue 3, Page(s) 271–280

    Abstract: Renal denervation is a novel catheter based approach that has been shown to effectively lower blood pressure in patients with resistant hypertension. Small studies have shown additional benefits in patients being treated for hypertension, such as ... ...

    Abstract Renal denervation is a novel catheter based approach that has been shown to effectively lower blood pressure in patients with resistant hypertension. Small studies have shown additional benefits in patients being treated for hypertension, such as improvements in insulin sensitivity, sleep apnoea and arrhythmias. More recently, it has been used for the first time for the treatment of sympathetic overactivation in patients with chronic systolic heart failure. Currently renal denervation therapy uses electrode-tipped catheters which deliver radio frequency energy to sympathetic afferent and efferent nerves running close to the lumen of the renal arteries. Further trials are on-going to assess the utility of this novel therapy in disease states beyond resistant hypertension.
    MeSH term(s) Clinical Trials as Topic ; Coronary Vasospasm ; Humans ; Hypertension/physiopathology ; Hypertension/surgery ; Kidney/innervation ; Kidney/surgery ; Patient Selection ; Randomized Controlled Trials as Topic ; Sympathectomy/methods ; Treatment Outcome
    Language English
    Publishing date 2013-06
    Publishing country Italy
    Document type Journal Article ; Review
    ZDB-ID 123583-7
    ISSN 1827-1618 ; 0026-4725
    ISSN (online) 1827-1618
    ISSN 0026-4725
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Book ; Online: Magnetoresistive Sensor Detectivity

    Davies, J. E. / Watts, J. D. / Novotny, J. / Huang, D. / Eames, P. G.

    A Comparative Analysis

    2021  

    Abstract: We report on the noise performance characteristics of magnetic sensors using both magnetic tunnel junction (MTJ) and giant magnetoresistance (GMR) elements. Each sensor studied has a notably different noise and detectivity. Of the sensors we measured, ... ...

    Abstract We report on the noise performance characteristics of magnetic sensors using both magnetic tunnel junction (MTJ) and giant magnetoresistance (GMR) elements. Each sensor studied has a notably different noise and detectivity. Of the sensors we measured, those based on GMR multilayers have the lowest noise and detectivity. However, the GMR sensor also has a significantly smaller linear range. To make a direct comparison between sensors we scale the linear operating ranges of each sensor to be the same. This is the phenomenological equivalent of modifying the flux concentration. Upon scaling the low frequency detectivity of the TMR sensors becomes essentially equal to that of the GMR sensor. Using the scaling approach we are able to place the detectivity in the context of other key parameters, namely size and power consumption. Lastly, we use this technique to examine the upper limit for magnetoresistive sensor performance based on a notional MTJ sensor using present record setting TMR values.

    Comment: Accepted to Applied Physics Letters, 6 pages, 7 figures
    Keywords Condensed Matter - Materials Science
    Subject code 620
    Publishing date 2021-01-28
    Publishing country us
    Document type Book ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  6. Article: Wave intensity analysis and its application to the coronary circulation.

    Broyd, C J / Davies, J E / Escaned, J E / Hughes, A / Parker, K

    Global cardiology science & practice

    2017  Volume 2017, Issue 1, Page(s) e201705

    Abstract: Wave intensity analysis (WIA) is a technique developed from the field of gas dynamics that is now being applied to assess cardiovascular physiology. It allows quantification of the forces acting to alter flow and pressure within a fluid system, and as ... ...

    Abstract Wave intensity analysis (WIA) is a technique developed from the field of gas dynamics that is now being applied to assess cardiovascular physiology. It allows quantification of the forces acting to alter flow and pressure within a fluid system, and as such it is highly insightful in ascribing cause to dynamic blood pressure or velocity changes. When co-incident waves arrive at the same spatial location they exert either counteracting or summative effects on flow and pressure. WIA however allows waves of different origins to be measured uninfluenced by other simultaneously arriving waves. It therefore has found particular applicability within the coronary circulation where both proximal (aortic) and distal (myocardial) ends of the coronary artery can markedly influence blood flow. Using these concepts, a repeating pattern of 6 waves has been consistently identified within the coronary arteries, 3 originating proximally and 3 distally. Each has been associated with a particular part of the cardiac cycle. The most clinically relevant wave to date is the backward decompression wave, which causes the marked increase in coronary flow velocity observed at the start of the diastole. It has been proposed that this wave is generated by the elastic re-expansion of the intra-myocardial blood vessels that are compressed during systolic contraction. Particularly by quantifying this wave, WIA has been used to provide mechanistic and prognostic insight into a number of conditions including aortic stenosis, left ventricular hypertrophy, coronary artery disease and heart failure. It has proven itself to be highly sensitive and as such a number of novel research directions are encouraged where further insights would be beneficial.
    Language English
    Publishing date 2017-03-31
    Publishing country Qatar
    Document type Journal Article ; Review
    ZDB-ID 2738381-7
    ISSN 2305-7823
    ISSN 2305-7823
    DOI 10.21542/gcsp.2017.5
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: The ASM in the new millennium.

    Davies, J E

    Trends in microbiology

    2000  Volume 8, Issue 5, Page(s) 193–194

    MeSH term(s) Forecasting ; History, 20th Century ; Microbiology/education ; Microbiology/history ; Periodicals as Topic ; Public Policy ; Publishing ; Societies, Scientific/history ; Societies, Scientific/trends ; United States
    Language English
    Publishing date 2000-05
    Publishing country England
    Document type Historical Article ; Journal Article
    ZDB-ID 1158963-2
    ISSN 1878-4380 ; 0966-842X
    ISSN (online) 1878-4380
    ISSN 0966-842X
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article: Hide and seek. Make sure HPV infection doesn't escape diagnosis.

    Davies, J E

    Advance for nurse practitioners

    2000  Volume 8, Issue 9, Page(s) 39–43

    MeSH term(s) Adjuvants, Immunologic/therapeutic use ; Aminoquinolines/therapeutic use ; Biopsy/methods ; Condylomata Acuminata/diagnosis ; Condylomata Acuminata/pathology ; Condylomata Acuminata/therapy ; Contraindications ; Cryotherapy ; Diagnosis, Differential ; Female ; Genital Diseases, Female/diagnosis ; Genital Diseases, Female/pathology ; Genital Diseases, Female/therapy ; Genital Diseases, Male/diagnosis ; Genital Diseases, Male/pathology ; Genital Diseases, Male/therapy ; Humans ; Keratolytic Agents/therapeutic use ; Male ; Podophyllin/therapeutic use ; Pregnancy
    Chemical Substances Adjuvants, Immunologic ; Aminoquinolines ; Keratolytic Agents ; Podophyllin (9000-55-9) ; imiquimod (P1QW714R7M)
    Language English
    Publishing date 2000-09
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 2060492-0
    ISSN 1096-6293
    ISSN 1096-6293
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Developing and paying for medicines for orphan indications in oncology: utilitarian regulation vs equitable care?

    Davies, J E / Neidle, S / Taylor, D G

    British journal of cancer

    2012  Volume 106, Issue 1, Page(s) 14–17

    Abstract: Despite 'orphan drug' legislation, bringing new medicines for rare diseases to market and securing funding for their provision is sometimes both costly and problematic, even in the case of medicines for very rare 'ultra orphan' oncological indications. ... ...

    Abstract Despite 'orphan drug' legislation, bringing new medicines for rare diseases to market and securing funding for their provision is sometimes both costly and problematic, even in the case of medicines for very rare 'ultra orphan' oncological indications. In this paper difficulties surrounding the introduction of a new treatment for osteosarcoma exemplify the challenges that innovators can face. The implications of current policy debate on 'value-based' medicines pricing in Europe, North America and elsewhere are also explored in the context of sustaining research into and facilitating cancer patient access to medicines for low-prevalence indications. Tensions exist between utilitarian strategies aimed at optimising the welfare of the majority in the society and minority-interest-focused approaches to equitable care provision. Current regulatory and pricing strategies should be revisited with the objective of facilitating fair and timely drug supply to patients without sacrificing safety or overall affordability. Failures effectively to tackle the problems considered here could undermine public interests in developing better therapies for cancer patients.
    MeSH term(s) Antineoplastic Agents/economics ; Drug Costs ; Health Services Accessibility ; Humans ; Neoplasms/drug therapy ; Orphan Drug Production/economics ; Social Justice
    Chemical Substances Antineoplastic Agents
    Language English
    Publishing date 2012-01-04
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't ; Review
    ZDB-ID 80075-2
    ISSN 1532-1827 ; 0007-0920
    ISSN (online) 1532-1827
    ISSN 0007-0920
    DOI 10.1038/bjc.2011.544
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article: Mechanisms of endosseous integration.

    Davies, J E

    The International journal of prosthodontics

    1998  Volume 11, Issue 5, Page(s) 391–401

    Abstract: Unlabelled: Although the clinical term "osseointegration" describes the anchorage of endosseous implants to withstand functional loading, it provides no insight into the mechanisms of bony healing around such implants. Nevertheless, an understanding of ... ...

    Abstract Unlabelled: Although the clinical term "osseointegration" describes the anchorage of endosseous implants to withstand functional loading, it provides no insight into the mechanisms of bony healing around such implants. Nevertheless, an understanding of the sequence of bone healing events around endosseous implants is believed to be critical in developing biologic design criteria for implant surfaces.
    Results and discussion: This discussion paper shows that peri-implant bone healing, which results in contact osteogenesis (bone growth on the implant surface), can be phenomenologically subdivided into three distinct phases that can be addressed experimentally. The first, osteoconduction, relies on the migration of differentiating osteogenic cells to the implant surface, through a temporary connective tissue scaffold. Anchorage of this scaffold to the implant surface is a function of implant surface design. The second, de novo bone formation, results in a mineralized interfacial matrix, equivalent to that seen in cement lines in natural bone tissue, being laid down on the implant surface. Implant surface topography will determine if the interfacial bone formed is bonded to the implant. A third tissue response, that of bone remodeling, will also, at discrete sites, create a bone-implant interface comprising de novo bone formation.
    Conclusion: Treatment outcomes in dental implantology will be critically dependent on implant surface designs that optimize the biologic response during each of these three distinct integration mechanisms.
    MeSH term(s) Animals ; Dental Implantation, Endosseous ; Dental Implants ; Osseointegration/physiology ; Osteogenesis/physiology ; Rats ; Treatment Outcome
    Chemical Substances Dental Implants
    Language English
    Publishing date 1998-09
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't ; Review
    ZDB-ID 645046-5
    ISSN 1942-4426 ; 0893-2174
    ISSN (online) 1942-4426
    ISSN 0893-2174
    Database MEDical Literature Analysis and Retrieval System OnLINE

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