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  1. Book: Handbook of neuropsychiatry research

    Davies, Rebecca S.

    (Neuroscience research progress ; Nova biomedical)

    2010  

    Author's details Rebecca S. Davies ed
    Series title Neuroscience research progress
    Nova biomedical
    Keywords Mental Disorders / physiopathology ; Nervous System / physiopathology
    Language English
    Size XI, 203 S. : Ill., graph. Darst., 23 cm
    Publisher Nova Science Publ
    Publishing place New York
    Publishing country United States
    Document type Book
    Note Includes bibliographical references and index
    HBZ-ID HT016374887
    ISBN 978-1-61668-138-8 ; 1-61668-138-1
    Database Catalogue ZB MED Medicine, Health

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    Shelf markLoan statusLocation
    2011 A 4319 order for loan Magazin

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  2. Article ; Online: Supporting each other: Older adults' experiences empowering food security and social inclusion in rural and food desert communities.

    Davies, Rebecca / Reid, Kate

    Appetite

    2024  Volume 198, Page(s) 107353

    Abstract: Older adults vulnerable to food insecurity are at risk of poor psychological and physical health. Poor public infrastructure or proximity to food sources can exacerbate risk of food insecurity. Reduced statutory services for social care has heightened ... ...

    Abstract Older adults vulnerable to food insecurity are at risk of poor psychological and physical health. Poor public infrastructure or proximity to food sources can exacerbate risk of food insecurity. Reduced statutory services for social care has heightened the responsibility on third sector organisations and community-led volunteering, essential to supporting healthy ageing in place and reducing the inequalities of ageing. The aim of this qualitative study was to explore how older adults' volunteering with a third sector organisation focused on food access supports food security and builds social capital for socially or economically marginalised older adults within rural and food desert communities. The study aims to bridge the knowledge gap of how volunteering in vulnerable geographies affects food insecurity and community. Semi-structured interviews were conducted with seven older (55+) volunteer 'meal makers' working with the third sector organisation Food Train and its 'Meal Makers' project. Interview recordings were transcribed and thematically analysed. Ecomap methodology was used to illustrate the lived experiences of older adult volunteers as told through the interviews. Two themes were identified by Thematic Analysis: (1) Networks, connectedness, and exposure to social capital, and (2) Supplementary support. This study finds that older adult volunteers are well placed within community interventions supporting food insecure older adults in rural or food desert communities. Ecomaps demonstrated that high social capital volunteers can mediate food access barriers and highlighted points of local knowledge and social connection. Volunteer engagement provides opportunities for food secure older adults to share local knowledge and build networks of food support and social inclusion for food insecure older adults. Older age volunteering should be advocated as a multi-faceted intervention promoting mutual health and wellbeing in volunteer and beneficiary.
    Language English
    Publishing date 2024-04-11
    Publishing country England
    Document type Journal Article
    ZDB-ID 1461347-5
    ISSN 1095-8304 ; 0195-6663
    ISSN (online) 1095-8304
    ISSN 0195-6663
    DOI 10.1016/j.appet.2024.107353
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Pericardial effusion secondary to epicardial undifferentiated pleomorphic sarcoma in a young cat.

    Stone, Marisa D / Davies, Rebecca K / Kridel, Heather A

    JFMS open reports

    2023  Volume 9, Issue 1, Page(s) 20551169231162484

    Abstract: Case summary: A 6.4 kg 3-year-old male neutered indoor-outdoor domestic shorthair cat was referred for further evaluation of non-resolving lethargy and hyporexia of 4 days' duration. Physical examination identified tachypnea with mild respiratory effort ...

    Abstract Case summary: A 6.4 kg 3-year-old male neutered indoor-outdoor domestic shorthair cat was referred for further evaluation of non-resolving lethargy and hyporexia of 4 days' duration. Physical examination identified tachypnea with mild respiratory effort and muffled lung sounds bilaterally. Point-of-care ultrasound revealed a large volume of pleural and pericardial effusion (PCE), which was confirmed by thoracic radiography. Echocardiogram indicated normal cardiac function but revealed a mass-like structure along the left epicardium within the pericardial space. After 72 hours in hospital, re-evaluation via echocardiogram showed the epicardial mass lesion to have doubled in size and with apparent extension to involve the pericardium. The patient was hospitalized for 72 h of supportive care and intervention, including therapeutic pericardiocentesis, bilateral thoracocentesis, thoracic and cardiac imaging and infectious disease testing. On the third day of hospitalization, the patient developed cardiac tamponade. Further workup was discussed, including CT and subtotal pericardiectomy with biopsy, but the cat was euthanized due to clinical decline and rapid re-accumulation of effusion. Post-mortem histopathologic evaluation diagnosed an epicardial pleomorphic sarcoma, exclusive of mesothelioma or histiocytic sarcoma on immunohistochemistry (IHC).
    Relevance and novel information: This report describes a case of epicardial undifferentiated pleomorphic sarcoma (UPS) in a young cat presenting with pleural and PCE. Pleomorphic sarcoma is a rarely reported mesenchymal neoplasia in the feline patient and has thus far primarily been identified in peripheral soft tissue structures. IHC is key to the correct histopathologic diagnosis. To our knowledge, epicardial UPS has not been previously reported in a cat.
    Language English
    Publishing date 2023-05-06
    Publishing country England
    Document type Case Reports
    ZDB-ID 2822177-1
    ISSN 2055-1169 ; 2055-1169
    ISSN (online) 2055-1169
    ISSN 2055-1169
    DOI 10.1177/20551169231162484
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Pericardial effusion secondary to epicardial undifferentiated pleomorphic sarcoma in a young cat

    Stone, Marisa D / Davies, Rebecca K / Kridel, Heather A

    Journal of Feline Medicine and Surgery Open Reports. 2023 May, v. 9, no. 1 p.20551169231162484-

    2023  

    Abstract: A 6.4 kg 3-year-old male neutered indoor–outdoor domestic shorthair cat was referred for further evaluation of non-resolving lethargy and hyporexia of 4 days’ duration. Physical examination identified tachypnea with mild respiratory effort and muffled ... ...

    Abstract A 6.4 kg 3-year-old male neutered indoor–outdoor domestic shorthair cat was referred for further evaluation of non-resolving lethargy and hyporexia of 4 days’ duration. Physical examination identified tachypnea with mild respiratory effort and muffled lung sounds bilaterally. Point-of-care ultrasound revealed a large volume of pleural and pericardial effusion (PCE), which was confirmed by thoracic radiography. Echocardiogram indicated normal cardiac function but revealed a mass-like structure along the left epicardium within the pericardial space. After 72 hours in hospital, re-evaluation via echocardiogram showed the epicardial mass lesion to have doubled in size and with apparent extension to involve the pericardium. The patient was hospitalized for 72 h of supportive care and intervention, including therapeutic pericardiocentesis, bilateral thoracocentesis, thoracic and cardiac imaging and infectious disease testing. On the third day of hospitalization, the patient developed cardiac tamponade. Further workup was discussed, including CT and subtotal pericardiectomy with biopsy, but the cat was euthanized due to clinical decline and rapid re-accumulation of effusion. Post-mortem histopathologic evaluation diagnosed an epicardial pleomorphic sarcoma, exclusive of mesothelioma or histiocytic sarcoma on immunohistochemistry (IHC). This report describes a case of epicardial undifferentiated pleomorphic sarcoma (UPS) in a young cat presenting with pleural and PCE. Pleomorphic sarcoma is a rarely reported mesenchymal neoplasia in the feline patient and has thus far primarily been identified in peripheral soft tissue structures. IHC is key to the correct histopathologic diagnosis. To our knowledge, epicardial UPS has not been previously reported in a cat.
    Keywords biopsy ; cardiac output ; cats ; clinical examination ; decline ; histopathology ; hospitals ; immunohistochemistry ; infectious diseases ; lungs ; males ; medicine ; mesothelioma ; patients ; pericardial effusion ; pericardium ; point-of-care systems ; radiography ; sarcoma ; tachypnea ; ultrasonics ; cardiac ; pericardial ; effusion ; pleomorphic
    Language English
    Dates of publication 2023-05
    Publishing place SAGE Publications
    Document type Article ; Online
    ZDB-ID 2822177-1
    ISSN 2055-1169
    ISSN 2055-1169
    DOI 10.1177/20551169231162484
    Database NAL-Catalogue (AGRICOLA)

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  5. Article: Regenerative Medicine: A Review of the Evolution of Autologous Chondrocyte Implantation (ACI) Therapy.

    Davies, Rebecca L / Kuiper, Nicola J

    Bioengineering (Basel, Switzerland)

    2019  Volume 6, Issue 1

    Abstract: Articular cartilage is composed of chondrons within a territorial matrix surrounded by a highly organized extracellular matrix comprising collagen II fibrils, proteoglycans, glycosaminoglycans, and non-collagenous proteins. Damaged articular cartilage ... ...

    Abstract Articular cartilage is composed of chondrons within a territorial matrix surrounded by a highly organized extracellular matrix comprising collagen II fibrils, proteoglycans, glycosaminoglycans, and non-collagenous proteins. Damaged articular cartilage has a limited potential for healing and untreated defects often progress to osteoarthritis. High hopes have been pinned on regenerative medicine strategies to meet the challenge of preventing progress to late osteoarthritis. One such strategy, autologous chondrocyte implantation (ACI), was first reported in 1994 as a treatment for deep focal articular cartilage defects. ACI has since evolved to become a worldwide well-established surgical technique. For ACI, chondrocytes are harvested from the lesser weight bearing edge of the joint by arthroscopy, their numbers expanded in monolayer culture for at least four weeks, and then re-implanted in the damaged region under a natural or synthetic membrane via an open joint procedure. We consider the evolution of ACI to become an established cell therapy, its current limitations, and on-going strategies to improve its efficacy. The most promising developments involving cells and natural or synthetic biomaterials will be highlighted.
    Language English
    Publishing date 2019-03-13
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2746191-9
    ISSN 2306-5354
    ISSN 2306-5354
    DOI 10.3390/bioengineering6010022
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Extracellular Vesicle Depletion Protocols of Foetal Bovine Serum Influence Umbilical Cord Mesenchymal Stromal Cell Phenotype, Immunomodulation, and Particle Release.

    Davies, Rebecca / Allen, Shannen / Mennan, Claire / Platt, Mark / Wright, Karina / Kehoe, Oksana

    International journal of molecular sciences

    2023  Volume 24, Issue 11

    Abstract: The immunomodulatory properties of MSCs can be recreated using their extracellular vesicles (EVs). Yet, the true capabilities of the MSC EVs cannot be distinguished from contaminating bovine EVs and protein derived from supplemental foetal bovine serum ( ... ...

    Abstract The immunomodulatory properties of MSCs can be recreated using their extracellular vesicles (EVs). Yet, the true capabilities of the MSC EVs cannot be distinguished from contaminating bovine EVs and protein derived from supplemental foetal bovine serum (FBS). FBS EV depletion protocols can minimise this, but vary in terms of depletion efficiency, which can negatively impact the cell phenotype. We explore the impact of FBS EV depletion strategies, including ultracentrifugation, ultrafiltration, and serum-free, on umbilical cord MSC characteristics. Whilst a greater depletion efficiency, seen in the ultrafiltration and serum-free strategies, did not impact the MSC markers or viability, the MSCs did become more fibroblastic, had slower proliferation, and showed inferior immunomodulatory capabilities. Upon MSC EV enrichment, more particles, with a greater particle/protein ratio, were isolated upon increasing the FBS depletion efficiency, except for serum-free, which showed a decreased particle number. Whilst all conditions showed the presence of EV-associated markers (CD9, CD63, and CD81), serum-free was shown to represent a higher proportion of these markers when normalised by total protein. Thus, we caution MSC EV researchers on the use of highly efficient EV depletion protocols, showing that it can impact the MSC phenotype, including their immunomodulatory properties, and stress the importance of testing in consideration to downstream objectives.
    MeSH term(s) Serum Albumin, Bovine/metabolism ; Umbilical Cord ; Extracellular Vesicles/metabolism ; Mesenchymal Stem Cells/metabolism ; Immunomodulation
    Chemical Substances Serum Albumin, Bovine (27432CM55Q)
    Language English
    Publishing date 2023-05-25
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2019364-6
    ISSN 1422-0067 ; 1422-0067 ; 1661-6596
    ISSN (online) 1422-0067
    ISSN 1422-0067 ; 1661-6596
    DOI 10.3390/ijms24119242
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  7. Article ; Online: Successful Treatment of Classical Loeffler's Endocarditis.

    Mohan, Nitin Chandra / Davies, Rebecca Rose / Kandasamy, Karikalan

    Journal of cardiovascular imaging

    2021  Volume 29, Issue 1, Page(s) 75–78

    Language English
    Publishing date 2021-01-28
    Publishing country Korea (South)
    Document type Case Reports
    ZDB-ID 3020035-0
    ISSN 2586-7296 ; 2586-7210
    ISSN (online) 2586-7296
    ISSN 2586-7210
    DOI 10.4250/jcvi.2020.0024
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  8. Article ; Online: Fertility preserving management for postpartum haemorrhage secondary to subinvolution of the placental implantation site.

    Du, Ruoxing / Davies, Rebecca / Supramaniam, Prasanna Raj

    BMJ case reports

    2021  Volume 14, Issue 9

    Abstract: A 40-year-old woman presents with recurrent secondary postpartum haemorrhage (PPH) following her third normal vaginal delivery. Histology from subsequent evacuation of the uterus confirmed that she had subinvolution of the placental implantation site. ... ...

    Abstract A 40-year-old woman presents with recurrent secondary postpartum haemorrhage (PPH) following her third normal vaginal delivery. Histology from subsequent evacuation of the uterus confirmed that she had subinvolution of the placental implantation site. Hysterectomy is the most common method of managing this condition and recurrent PPH, most often due to significant vaginal bleeding. We present a case of subinvolution of the placental implantation site with recurrent PPH managed with medical treatment alone, to offer a fertility-sparing treatment option.
    MeSH term(s) Adult ; Delivery, Obstetric ; Female ; Humans ; Hysterectomy ; Placenta ; Postpartum Hemorrhage/etiology ; Postpartum Hemorrhage/surgery ; Pregnancy ; Uterus
    Language English
    Publishing date 2021-09-30
    Publishing country England
    Document type Case Reports ; Journal Article
    ISSN 1757-790X
    ISSN (online) 1757-790X
    DOI 10.1136/bcr-2021-245009
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Metastatic Adrenocortical Carcinoma Causing Profound Right Ventricular Outflow Tract Obstruction: An Improvement Following Surgical Resection.

    Chandramohan, Nitin / Davies, Rebecca Rose / Al-Sakini, Nada

    Circulation. Cardiovascular imaging

    2020  Volume 13, Issue 5, Page(s) e010058

    MeSH term(s) Adrenal Cortex Neoplasms/pathology ; Adrenocortical Carcinoma/complications ; Adrenocortical Carcinoma/diagnostic imaging ; Adrenocortical Carcinoma/secondary ; Adrenocortical Carcinoma/surgery ; Cardiac Surgical Procedures ; Heart Neoplasms/complications ; Heart Neoplasms/diagnostic imaging ; Heart Neoplasms/secondary ; Heart Neoplasms/surgery ; Humans ; Male ; Metastasectomy ; Middle Aged ; Recovery of Function ; Treatment Outcome ; Ventricular Outflow Obstruction/diagnostic imaging ; Ventricular Outflow Obstruction/etiology ; Ventricular Outflow Obstruction/surgery
    Language English
    Publishing date 2020-05-06
    Publishing country United States
    Document type Case Reports ; Video-Audio Media
    ZDB-ID 2435045-X
    ISSN 1942-0080 ; 1941-9651
    ISSN (online) 1942-0080
    ISSN 1941-9651
    DOI 10.1161/CIRCIMAGING.119.010058
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 6743: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

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  10. Article ; Online: Successful treatment of severe COVID-19 pneumonia and hyperinflammatory syndrome with tocilizumab.

    Gentile, Giorgio / Davies, Rebecca / Manfreda, Valeria Maria / Ul Abideen, Zain

    BMJ case reports

    2021  Volume 14, Issue 1

    Abstract: As of 28 October 2020, there are over 44 000 000 confirmed COVID-19 infections and over 1 000 000 deaths worldwide, including 945 367 infections and 45 765 deaths in the UK. Acute respiratory distress syndrome occurs in 50% of patients with secondary ... ...

    Abstract As of 28 October 2020, there are over 44 000 000 confirmed COVID-19 infections and over 1 000 000 deaths worldwide, including 945 367 infections and 45 765 deaths in the UK. Acute respiratory distress syndrome occurs in 50% of patients with secondary haemophagocytic lymphohistiocytosis, a hyperinflammatory syndrome characterised by a surge of cytokines, including interleukin 6 (IL-6). Here we describe the case of the first patient with severe COVID-19 pneumonia successfully treated with tocilizumab, a humanised monoclonal antibody against the IL-6 receptor, in the UK. Early treatment (after 7-10 days from the onset of symptoms) with tocilizumab could (1) reduce the risk of requiring non-invasive or invasive ventilation; (2) offer a chance of survival to people who are not fit for escalation or have refused to be ventilated; and (3) potentially increase the chance of survival in some patients who are already ventilated but fail to improve with supportive treatment.
    MeSH term(s) Aged ; Antibodies, Monoclonal, Humanized/therapeutic use ; COVID-19/complications ; COVID-19/drug therapy ; COVID-19/physiopathology ; Diabetes Mellitus, Type 2/complications ; Humans ; Hypertension/complications ; Hypoxia/physiopathology ; Hypoxia/therapy ; Male ; Oxygen Inhalation Therapy ; Receptors, Interleukin-6/antagonists & inhibitors ; SARS-CoV-2 ; Severity of Illness Index
    Chemical Substances Antibodies, Monoclonal, Humanized ; Receptors, Interleukin-6 ; tocilizumab (I031V2H011)
    Language English
    Publishing date 2021-01-08
    Publishing country England
    Document type Case Reports ; Journal Article
    ISSN 1757-790X
    ISSN (online) 1757-790X
    DOI 10.1136/bcr-2020-238210
    Database MEDical Literature Analysis and Retrieval System OnLINE

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