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Article ; Online: Stop ticking and start talking.

Davin, Elaine

Nursing standard (Royal College of Nursing (Great Britain) : 1987)

2017 Volume 31, Issue 36, Page(s) 30

Abstract: Your story about intentional rounding (news online, 5 April) reminded me of the 'back rounds' we did, where every patient who had difficulty attending to their activities of daily living was repositioned and asked how their day was going and how they ... ...

Abstract	Your story about intentional rounding (news online, 5 April) reminded me of the 'back rounds' we did, where every patient who had difficulty attending to their activities of daily living was repositioned and asked how their day was going and how they were feeling.
Language	English
Publishing date	2017-05-02
Publishing country	England
Document type	Journal Article
ZDB-ID	645016-7
ISSN	2047-9018 ; 0029-6570
ISSN (online)	2047-9018
ISSN	0029-6570
DOI	10.7748/ns.31.36.30.s29
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Zs.A 2410: Show issues			Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular Jg. 1995 - 2021: Lesesall (2.OG) ab Jg. 2022: Lesesaal (EG)
Zs.MO 273: Show issues

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Article ; Online: Reticulocyte hemoglobin content and iron therapy in CKD.

Deira, Javier / García de la Vega, Cristina / Davín, Elena / Arcos, María José

Nefrologia

2023 Volume 42, Issue 6, Page(s) 736–737

MeSH term(s)	Humans ; Reticulocytes ; Hemoglobins ; Iron ; Renal Insufficiency, Chronic/complications ; Renal Insufficiency, Chronic/therapy
Chemical Substances	Hemoglobins ; Iron (E1UOL152H7)
Language	English
Publishing date	2023-02-25
Publishing country	Spain
Document type	Letter ; Comment
ZDB-ID	2837917-2
ISSN	2013-2514 ; 2013-2514
ISSN (online)	2013-2514
ISSN	2013-2514
DOI	10.1016/j.nefroe.2021.04.016
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Article ; Online: Global forestation and deforestation affect remote climate via adjusted atmosphere and ocean circulation.

Portmann, Raphael / Beyerle, Urs / Davin, Edouard / Fischer, Erich M / De Hertog, Steven / Schemm, Sebastian

Nature communications

2022 Volume 13, Issue 1, Page(s) 5569

Abstract: Forests can store large amounts of carbon and provide essential ecosystem services. Massive tree planting is thus sometimes portrayed as a panacea to mitigate climate change and related impacts. Recent controversies about the potential benefits and ... ...

Abstract	Forests can store large amounts of carbon and provide essential ecosystem services. Massive tree planting is thus sometimes portrayed as a panacea to mitigate climate change and related impacts. Recent controversies about the potential benefits and drawbacks of forestation have centered on the carbon storage potential of forests and the local or global thermodynamic impacts. Here we discuss how global-scale forestation and deforestation change the Earth's energy balance, thereby affect the global atmospheric circulation and even have profound effects on the ocean circulation. We perform multicentury coupled climate model simulations in which preindustrial vegetation cover is either completely forested or deforested and carbon dioxide mixing ratio is kept constant. We show that global-scale forestation leads to a weakening and poleward shift of the Northern mid-latitude circulation, slows-down the Atlantic meridional overturning circulation, and affects the strength of the Hadley cell, whereas deforestation leads to reversed changes. Consequently, both land surface changes substantially affect regional precipitation, temperature, clouds, and surface wind patterns across the globe. The design process of large-scale forestation projects thus needs to take into account global circulation adjustments and their influence on remote climate.
MeSH term(s)	Atmosphere ; Carbon Dioxide ; Climate Change ; Conservation of Natural Resources ; Ecosystem ; Oceans and Seas
Chemical Substances	Carbon Dioxide (142M471B3J)
Language	English
Publishing date	2022-10-04
Publishing country	England
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2553671-0
ISSN	2041-1723 ; 2041-1723
ISSN (online)	2041-1723
ISSN	2041-1723
DOI	10.1038/s41467-022-33279-9
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Article ; Online: Reticulocyte hemoglobin content and iron therapy in CKD.

Deira, Javier / García de la Vega, Cristina / Davín, Elena / Arcos, María José

Nefrologia

2021

Title translation	Concentración de hemoglobina reticulocitaria y ferroterapia en la ERC.
Language	Spanish
Publishing date	2021-06-28
Publishing country	Spain
Document type	Letter
ZDB-ID	2837917-2
ISSN	2013-2514 ; 2013-2514
ISSN (online)	2013-2514
ISSN	2013-2514
DOI	10.1016/j.nefro.2021.04.005
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Article ; Online: Topical pain control for corneal abrasions: A systematic review and meta-analysis.

Yu, Caberry W / Kirubarajan, Abirami / Yau, Matthew / Armstrong, Dawn / Johnson, Davin E

Academic emergency medicine : official journal of the Society for Academic Emergency Medicine

2021 Volume 28, Issue 8, Page(s) 890–908

Abstract: Objectives: Corneal abrasions are common ophthalmic presentations to emergency departments. Among emergency physicians and ophthalmologists, there are highly variable practice patterns with regard to management of resultant pain and discomfort. The goal ...

Abstract	Objectives: Corneal abrasions are common ophthalmic presentations to emergency departments. Among emergency physicians and ophthalmologists, there are highly variable practice patterns with regard to management of resultant pain and discomfort. The goal of this study was to review and analyze the efficacy and safety of topical pain therapies for corneal abrasions, including topical anesthetics, nonsteroidal anti-inflammatory drugs (NSAIDs), cycloplegics, steroids, pressure patching, and the use of a bandage contact lens (BCL). Methods: The review followed the Preferred Reporting Items for Systematic Review and Meta-analysis (PRISMA) guidelines. The protocol was established a priori and published on PROSPERO (CRD42020201288). MEDLINE, EMBASE, CENTRAL, and Web of Science were searched until December 31, 2020. Primary studies comparing topical pain therapies to another therapy or control were included. Primary outcomes included percentage of corneal abrasions healed at 24, 48, and 72 hours, as well as pain control at 24 and 48 hours. Secondary outcomes included use of oral analgesia and incidence of complications. Risk of bias was assessed using validated tools. Quality of evidence was assessed using the GRADE methodology. Results: Overall, 33 studies (31 randomized controlled trials [RCTs], two cohort studies) comprising 4,167 patients with corneal abrasions were analyzed. Only the data for topical NSAIDs were of adequate evidence from which to draw conclusions; topical NSAIDs demonstrated significantly reduced pain scores at 24 hours (standardized mean differences [SMD] -0.69, 95% CI = -0.98 to -0.41) and 48 hours (SMD = -0.56, 95% CI = -1.02 to -0.10) as well as 53% (95% CI = 34% to 67%) lower oral analgesia use compared to control. Based on available data, topical anesthetics, cycloplegics, patching, and the use of a BCL did not result in any significant difference in pain scores or use of oral analgesia, while no studies examined topical steroids. No interventions resulted in healing delays or significantly higher rates of complications compared to controls. Conclusions: There was strong evidence to support that topical NSAIDs reduce pain associated with corneal abrasions in the first 48 hours and the need for oral analgesia. The existing evidence was insufficient to support or refute the use of topical anesthetics, cycloplegics, steroids, or BCL for pain control in corneal abrasions. Pressure patching was ineffective at pain reduction and may increase the risk of complications. Delays in healing or other complications were not significantly different between any intervention or control for simple, uncomplicated corneal abrasions; however, larger RCTs are required to identify any differences in rare complications.
MeSH term(s)	Analgesia ; Anti-Inflammatory Agents, Non-Steroidal/therapeutic use ; Corneal Injuries/complications ; Humans ; Pain/drug therapy ; Pain/etiology ; Pain Management
Chemical Substances	Anti-Inflammatory Agents, Non-Steroidal
Language	English
Publishing date	2021-03-05
Publishing country	United States
Document type	Journal Article ; Meta-Analysis ; Systematic Review
ZDB-ID	1329813-6
ISSN	1553-2712 ; 1069-6563
ISSN (online)	1553-2712
ISSN	1069-6563
DOI	10.1111/acem.14222
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Article ; Online: Design and Validation of a Training Simulator for Laser Capsulotomy, Peripheral Iridotomy, and Retinopexy.

Simpson, Sarah M / Schweitzer, Kelly D / Johnson, Davin E

Ophthalmic surgery, lasers & imaging retina

2017 Volume 48, Issue 1, Page(s) 56–61

Abstract: Background and objectives: Ophthalmology trainees commonly learn laser procedures on live patients. A simulator for learning peripheral iridotomy (PI), posterior capsulotomy, and retinopexy may improve patient outcomes.: Materials and methods: A ... ...

Abstract	Background and objectives: Ophthalmology trainees commonly learn laser procedures on live patients. A simulator for learning peripheral iridotomy (PI), posterior capsulotomy, and retinopexy may improve patient outcomes. Materials and methods: A model eye with artificial tissues was designed. The tissues reacted to laser similarly to human tissues. Inexperienced (n = 6; first- to third-year residents) and experienced (n = 7; fourth- to fifth-year residents and staff) ophthalmic personal were compared on performance of the above laser procedures. Results: The inexperienced group required more shots (P = .04) and caused more lens markings (P = .04) during capsulotomy and had more incomplete retinopexy results (P = .04) than the experienced group. The groups did not differ in total shots for PI, average power for retinopexy, or the total time required for any of the procedures. Conclusion: Our model effectively simulates common ophthalmic laser procedures and is practical for the training of ophthalmology residents. [Ophthalmic Surg Lasers Imaging Retina. 2017;48:56-61.].
MeSH term(s)	Education, Medical, Graduate/methods ; Humans ; Iris/surgery ; Laser Therapy/methods ; Lasers, Solid-State/therapeutic use ; Ophthalmology/education ; Patient Simulation ; Posterior Capsulotomy/education ; Simulation Training/methods
Language	English
Publishing date	2017-01-01
Publishing country	United States
Document type	Journal Article ; Validation Studies
ZDB-ID	2701167-7
ISSN	2325-8179 ; 2325-8160
ISSN (online)	2325-8179
ISSN	2325-8160
DOI	10.3928/23258160-20161219-08
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Zs.A 756: Show issues

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Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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Jg. 1995 - 2021: Lesesall (1.OG)
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Article ; Online: Detección y clasificación de la enfermedad renal crónica en Atención Primaria y la importancia de la albuminuria.

Labrador, P J / González-Sanchidrián, S / Polanco, S / Davin, E / Fuentes, J M / Gómez-Martino, J R

Semergen

2017 Volume 44, Issue 2, Page(s) 82–89

Abstract: Introduction: Chronic kidney disease (CKD) is a public health problem, and Primary Care (PC) plays a key role in its detection and classification based on estimated glomerular filtration rate (eGFR), as well as the level of albuminuria for its proper ... ...

Title translation	Detection and classification of chronic kidney disease in Primary Care and importance of albuminuria.
Abstract	Introduction: Chronic kidney disease (CKD) is a public health problem, and Primary Care (PC) plays a key role in its detection and classification based on estimated glomerular filtration rate (eGFR), as well as the level of albuminuria for its proper management. The aim of this study was to analyse the prevalence and classification of CKD in patients attended in PC. Material and methods: An analysis was made of CKD prevalence and classification according to the Kidney Disease-Improving Global Outcomes guidelines in PC patients. All biochemical analyses requested from PC on patients 18 years and older over a 5-year period were collected. When several analyses were available on a patient, the biochemistry result with the best eGFR was selected. Results: Between 2010 and 2014, PC requested 304,523 biochemical analyses on 97,470 adult patients, with a mean age of 53.4±19.4 years, of which 57.2% were women. CKD prevalence was 7.6%. Urine protein results were present in only 16.6% of analyses, and only 15.2% patients had a urine protein result. Urine albumin was measured 15.4% of biochemical controls with eGFR≥60mL/min/1.73m Conclusions: Requests for the measurement of urine proteins/albumin in PC patients are low, leading to only one in 6 PC patients being classified correctly. The measurement of urine proteins/albumin is higher in CKD and diabetic patients.
MeSH term(s)	Adult ; Aged ; Albuminuria/epidemiology ; Albuminuria/etiology ; Diabetes Mellitus/epidemiology ; Female ; Glomerular Filtration Rate ; Glucose Intolerance/epidemiology ; Humans ; Male ; Middle Aged ; Practice Guidelines as Topic ; Prevalence ; Primary Health Care ; Proteinuria/epidemiology ; Proteinuria/etiology ; Renal Insufficiency, Chronic/classification ; Renal Insufficiency, Chronic/diagnosis ; Renal Insufficiency, Chronic/epidemiology
Language	Spanish
Publishing date	2017-02-13
Publishing country	Spain
Document type	Journal Article
ISSN	1578-8865
ISSN (online)	1578-8865
DOI	10.1016/j.semerg.2016.11.009
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Article ; Online: Identifying and appraising outcome measures for severe asthma: a systematic review.

The European respiratory journal

2023 Volume 61, Issue 4

Abstract: Background: Valid outcome measures are imperative to evaluate treatment response, yet the suitability of existing end-points for severe asthma is unclear. This review aimed to identify outcome measures for severe asthma and appraise the quality of their ...

Abstract	Background: Valid outcome measures are imperative to evaluate treatment response, yet the suitability of existing end-points for severe asthma is unclear. This review aimed to identify outcome measures for severe asthma and appraise the quality of their measurement properties. Methods: A literature search was performed to identify "candidate" outcome measures published between 2018 and 2020. A modified Delphi exercise was conducted to select "key" outcome measures within healthcare professional, patient, pharmaceutical and regulatory stakeholder groups. Initial validation studies for "key" measures were rated against modified quality criteria from COnsensus-based Standards for the selection of health Measurement INstruments (COSMIN). The evidence was discussed at multi-stakeholder meetings to ratify "priority" outcome measures. Subsequently, four bibliographic databases were searched from inception to 20 July 2020 to identify development and validation studies for these end-points. Two reviewers screened records, extracted data, assessed their methodological quality and graded the evidence according to COSMIN. Results: 96 outcome measures were identified as "candidates", 55 as "key" and 24 as "priority" for severe asthma, including clinical, healthcare utilisation, quality of life, asthma control and composite. 32 studies reported measurement properties of 17 "priority" end-points from the latter three domains. Only the Severe Asthma Questionnaire and Childhood Asthma Control Test were developed with input from severe asthma patients. The certainty of evidence was "low" to "very low" for most "priority" end-points across all measurement properties and none fulfilled all quality standards. Conclusions: Only two outcome measures had robust developmental data for severe asthma. This review informed development of core outcome measures sets for severe asthma.
MeSH term(s)	Humans ; Child ; Quality of Life ; Asthma/drug therapy ; Outcome Assessment, Health Care ; Delivery of Health Care ; Surveys and Questionnaires
Language	English
Publishing date	2023-04-03
Publishing country	England
Document type	Systematic Review ; Journal Article ; Review ; Research Support, Non-U.S. Gov't
ZDB-ID	639359-7
ISSN	1399-3003 ; 0903-1936
ISSN (online)	1399-3003
ISSN	0903-1936
DOI	10.1183/13993003.01231-2022
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Book ; Article ; Online: The COSMO-CLM 4.8 regional climate model coupled to regional ocean, land surface and global earth system models using OASIS3-MCT

Will, A. / Akhtar, N. / Brauch, J. / Breil, M. / Davin, E. / Ho-Hagemann, H.T.M. / Maisonnave, E. / Thuerkow, M. / Weiher, S.

Geoscientific Model Development ; 1991-959X

description and performance

2017

Abstract: We developed a coupled regional climate system model based on the CCLM regional climate model. Within this model system, using OASIS3-MCT as a coupler, CCLM can be coupled to two land surface models (Community Land Model (CLM) and VEG3D), the NEMO-MED12 ... ...

Abstract	We developed a coupled regional climate system model based on the CCLM regional climate model. Within this model system, using OASIS3-MCT as a coupler, CCLM can be coupled to two land surface models (Community Land Model (CLM) and VEG3D), the NEMO-MED12 regional ocean model for the Mediterranean Sea, two ocean models for the North and Baltic Sea (NEMO-NORDIC and TRIMNP+CICE) and the earth system model MPI-ESM. We first present the different model components and the unified OASIS3-MCT interface which handles all couplings in a consistent way, minimizing the model source code modifications and defining the physical and numerical aspects of the couplings. We also address specific coupling issues like the handling of different domains, multiple usage of MCT library and exchange of 3D fields. We analyse and compare the computational performance of the different couplings based on realcase simulations over Europe. The usage of the LUCIA tool implemented in OASIS3-MCT enables the quantification of the contributions of the coupled components to the overall coupling cost. These individual contributions are (1) cost of the model(s) coupled, (2) direct cost of coupling including horizontal interpolation and communication between the components, (3) load imbalance, (4) cost of different usage of processors by CCLM in coupled and stand alone mode and (5) residual cost including i.a. CCLM additional computations. Finally a procedure for finding an optimum processor configuration for each of the couplings was developed considering the time to solution, computing cost and parallel efficiency of the simulation. The optimum configurations are presented for sequential, concurrent and mixed (sequential+ concurrent) coupling layouts. The procedure applied can be regarded as independent of the specific coupling layout and coupling details. We found that the direct cost of coupling, i.e. communications and horizontal interpolation, in OASIS3-MCT remains below 7% of the CCLM stand-alone cost for all couplings investigated. This is in particular true for the exchange of 450 2D fields between CCLM and MPI-ESM. We identified remaining limitations in the coupling strategies and discuss possible future improvements of the computational efficiency.
Keywords	PACES II
Subject code	551
Publisher	GKSS Forschungszentrum Geesthacht GmbH
Publishing country	de
Document type	Book ; Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Book ; Article ; Online: Coupling of the regional climate model COSMO-CLM using OASIS3-MCT with regional ocean, land surface or global atmosphere model

Weiher, S. / Akhtar, N. / Brauch, J. / Breil, M. / Davin, E. / Ho-Hagemann, H.T.M. / Maisonnave, E. / Thuerkow, M. / Will, A.

Geoscientific Model Development Discussions [Online Ressource] ; 1991-9611

description and performance

2016

Abstract: We present the prototype of a regional climate system model based on the COSMO-CLM regional climate model coupled with several model components, analyze the performance of the couplings and present a strategy to find an optimum configuration with respect ...

Abstract	We present the prototype of a regional climate system model based on the COSMO-CLM regional climate model coupled with several model components, analyze the performance of the couplings and present a strategy to find an optimum configuration with respect to computational costs and time to solution. The OASIS3-MCT coupler is used to couple COSMO-CLM with two land surface models (CLM and VEG3D), a regional ocean model for the Mediterranean Sea (NEMO-MED12), two ocean models for the North and Baltic Sea (NEMO-NORDIC and TRIMNP+CICE) and the atmospheric component of an earth system model (MPI-ESM). We present a unified OASIS3-MCT interface which handles all couplings in a similar way, minimizes the model source code modifications and describes the physics and numerics of the couplings. Furthermore, we discuss solutions for specific regional coupling problems like handling of different domains, multiple usage of MCT interpolation library and efficient exchange of 3D fields. A series of real-case simulations over Europe has been conducted and the computational performance of the couplings has been analyzed. The usage of the LUCIA tool of the OASIS3-MCT coupler enabled separation of the direct costs of: coupling, load imbalance and additional computations. The resulting limits for time to solution and costs are shown and the potential of further improvement of the computational efficiency is summarized for each coupling. It was found that the OASIS3-MCT coupler keeps the direct coupling costs of communication and horizontal interpolation small in comparison with the costs of the additional computations and load imbalance for all investigated couplings. For the first time this could be demonstrated for an exchange of approximately 450 2D fields per time step necessary for the atmosphere-atmosphere coupling between COSMO-CLM and MPI-ESM. A procedure for finding an optimum configuration for each of the couplings was developed considering the time to solution and costs of the simulations. The optimum configurations are presented for sequential and concurrent coupling layouts. The procedure applied can be regarded as independent on the specific coupling layout and coupling details.
Keywords	Marine ; Coastal and Polar Systems ; 551
Subject code	551
Publisher	GKSS Forschungszentrum Geesthacht GmbH
Publishing country	de
Document type	Book ; Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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