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  1. Article ; Online: Nonequilibrium Transport in a Superfluid Josephson Junction Chain: Is There Negative Differential Conductivity?

    Begg, Samuel E / Davis, Matthew J / Reeves, Matthew T

    Physical review letters

    2024  Volume 132, Issue 10, Page(s) 103402

    Abstract: We consider the far-from-equilibrium quantum transport dynamics in a 1D Josephson junction chain of multimode Bose-Einstein condensates. We develop a theoretical model to examine the experiment of Labouvie et al. [Phys. Rev. Lett. 115, 050601 (2015) ... ...

    Abstract We consider the far-from-equilibrium quantum transport dynamics in a 1D Josephson junction chain of multimode Bose-Einstein condensates. We develop a theoretical model to examine the experiment of Labouvie et al. [Phys. Rev. Lett. 115, 050601 (2015)PRLTAO0031-900710.1103/PhysRevLett.115.050601], wherein the phenomenon of negative differential conductivity (NDC) was reported in the refilling dynamics of an initially depleted site within the chain. We demonstrate that a unitary c-field description can quantitatively reproduce the experimental results over the full range of tunnel couplings, and requires no fitted parameters. With a view toward atomtronic implementations, we further demonstrate that the filling is strongly dependent on spatial phase variations stemming from quantum fluctuations. Our findings suggest that the interpretation of the device in terms of NDC is invalid outside of the weak coupling regime. Within this restricted regime, the device exhibits a hybrid behavior of NDC and the ac Josephson effect. A simplified circuit model of the device will require an approach tailored to atomtronics that incorporates quantum fluctuations.
    Language English
    Publishing date 2024-03-22
    Publishing country United States
    Document type Journal Article
    ZDB-ID 208853-8
    ISSN 1079-7114 ; 0031-9007
    ISSN (online) 1079-7114
    ISSN 0031-9007
    DOI 10.1103/PhysRevLett.132.103402
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  2. Article: Using Technology to Combat Clinician Burnout.

    Davis, Matthew J

    Journal of healthcare management / American College of Healthcare Executives

    2020  Volume 65, Issue 4, Page(s) 265–272

    Abstract: Executive summary: Physician burnout is a major problem affecting healthcare providers. It not only influences clinician mental health but also clinical outcomes, patient satisfaction, and the financial standing of a health system. A combination of web ... ...

    Abstract Executive summary: Physician burnout is a major problem affecting healthcare providers. It not only influences clinician mental health but also clinical outcomes, patient satisfaction, and the financial standing of a health system. A combination of web and mobile applications can be used to treat clinician burnout by effectively reducing stress, anxiety, and depression. When included in a well-structured program, these technology-based tools provide improved access to mental health treatments for clinicians, help remove the stigma of therapy, and reduce clinician burnout caused by job stressors.
    MeSH term(s) Burnout, Professional/prevention & control ; Health Personnel/psychology ; Humans ; Software ; Technology
    Language English
    Publishing date 2020-07-08
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1418083-2
    ISSN 1944-7396 ; 1096-9012
    ISSN (online) 1944-7396
    ISSN 1096-9012
    DOI 10.1097/JHM-D-20-00099
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  3. Article ; Online: Integration of a deep learning basal cell carcinoma detection and tumor mapping algorithm into the Mohs micrographic surgery workflow and effects on clinical staffing: A simulated, retrospective study.

    Chacko, Rachael / Davis, Matthew J / Levy, Joshua / LeBoeuf, Matthew

    JAAD international

    2024  Volume 15, Page(s) 185–191

    Abstract: Background: Artificial intelligence (AI) enabled tools have been proposed as 1 solution to improve health care delivery. However, research on downstream effects of AI integration into the clinical workflow is lacking.: Objective: We aim to analyze ... ...

    Abstract Background: Artificial intelligence (AI) enabled tools have been proposed as 1 solution to improve health care delivery. However, research on downstream effects of AI integration into the clinical workflow is lacking.
    Objective: We aim to analyze how integration of an automated basal cell carcinoma detection and tumor mapping algorithm in a Mohs micrographic surgery unit impacts the work efficiency of clinical and laboratory staff.
    Methods: Slide, staff, and histotechnician waiting times were analyzed over a 20-day period in a Mohs micrographic surgery unit. A simulated AI workflow was created and the time differences between the real and simulated workflows were compared.
    Results: Simulated nonautonomous algorithm integration led to savings of 35.6% of slide waiting time, 18.4% of staff waiting time, and 18.6% of histotechnician waiting time per day. Algorithm integration on days with increased reconstruction complexity resulted in the greatest time savings.
    Limitations: One Mohs micrographic surgery unit was analyzed and simulated AI integration was performed retrospectively.
    Conclusions: AI integration results in reduced staff waiting times, enabling increased productivity and a streamlined clinical workflow. Schedules containing surgical cases with either increased repair complexity or numerous tumor removal stages stand to benefit most. However, significant logistical challenges must be addressed before broad adoption into clinical practice is realistic.
    Language English
    Publishing date 2024-03-01
    Publishing country United States
    Document type Journal Article
    ISSN 2666-3287
    ISSN (online) 2666-3287
    DOI 10.1016/j.jdin.2024.02.014
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  4. Article: Triggering multiple sclerosis at conception and early gestation: The variation in ultraviolet radiation is as important as its intensity.

    Davis, George E / Davis, Matthew J / Lowell, Walter E

    Heliyon

    2023  Volume 9, Issue 6, Page(s) e16954

    Abstract: Background and objectives: Medical science needs to further elucidate the role of ultraviolet radiation (UVR), geographic latitude, and the role of vitamin D in the autoimmune disease multiple sclerosis (MS). We separated several papers into categories ... ...

    Abstract Background and objectives: Medical science needs to further elucidate the role of ultraviolet radiation (UVR), geographic latitude, and the role of vitamin D in the autoimmune disease multiple sclerosis (MS). We separated several papers into categories out of the thousands published and used their conclusions to explore the relationship between UVR and MS.
    Relevance: MS is increasing in incidence, particularly in women where MS is two to three times that in men and particularly severe in African Americans.
    Methods: We collected UVR data at our observatory in Central Maine and calculated the average coefficient of variation (CV
    Results: The month of conception (MOC) is more important than the month of birth (MOB) in explaining how UVR triggers the variable genetic predisposition to MS. We hypothesize that the rapidly increasing CV
    Limitations: One observatory at about 44° latitude.
    Conclusions: While variation in UVR is important at the MOC if UVR exceeds a threshold (e.g., if the sunspot number equals or is greater than 90, usually at a solar cycle MAX, or at elevations above approximately 3,000 feet above sea level), the MS mitigating vitamin D-VDR mechanism is overwhelmed and the genotoxic effects of higher-intensity UVR promote MS in those with a genetic predisposition.
    What is new in this research: This paper offers a new concept in MS research.
    Language English
    Publishing date 2023-06-03
    Publishing country England
    Document type Journal Article
    ZDB-ID 2835763-2
    ISSN 2405-8440
    ISSN 2405-8440
    DOI 10.1016/j.heliyon.2023.e16954
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  5. Article ; Online: Fifteen-Year Outcomes of the ProtecT Trial for Localized Prostate Cancer.

    Davis, Matthew J / Stephens, Alex / Abdollah, Firas

    The New England journal of medicine

    2023  Volume 389, Issue 1, Page(s) 90–92

    MeSH term(s) Male ; Humans ; Prostatic Neoplasms/therapy ; Prostate-Specific Antigen
    Chemical Substances Prostate-Specific Antigen (EC 3.4.21.77)
    Language English
    Publishing date 2023-07-03
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 207154-x
    ISSN 1533-4406 ; 0028-4793
    ISSN (online) 1533-4406
    ISSN 0028-4793
    DOI 10.1056/NEJMc2306135
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  6. Book ; Online: Many-body enhancement in a spin-chain quantum heat engine

    Williamson, L. A. / Davis, Matthew J.

    2023  

    Abstract: We show that ferromagnetic interactions can enhance the adiabatic performance of a quantum spin chain engine at low temperatures. The enhancement in work output is particular pronounced, increasing exponentially with interaction strength. The performance ...

    Abstract We show that ferromagnetic interactions can enhance the adiabatic performance of a quantum spin chain engine at low temperatures. The enhancement in work output is particular pronounced, increasing exponentially with interaction strength. The performance enhancement occurs in the paramagnetic phase and is qualitatively explained by considering just the ground and first excited state, in which case the system exhibits bipartite entanglement. As the temperature is increased, thermal occupation of higher energy levels diminishes performance. We find that these thermal fluctuations are smallest for long-range interactions, resulting in the highest efficiency. Diabatic work extraction degrades performance due to quantum friction. We identify an approximate, experimentally realisable counterdiabatic drive that can mitigate friction for weak interactions.

    Comment: 4 pages + refs + supplement, 3 figures
    Keywords Quantum Physics ; Condensed Matter - Quantum Gases
    Subject code 612
    Publishing date 2023-02-03
    Publishing country us
    Document type Book ; Online
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  7. Article: Exploring the Potential and Limitations of Chat Generative Pre-trained Transformer (ChatGPT) in Generating Board-Style Dermatology Questions: A Qualitative Analysis.

    Ayub, Ibraheim / Hamann, Dathan / Hamann, Carsten R / Davis, Matthew J

    Cureus

    2023  Volume 15, Issue 8, Page(s) e43717

    Abstract: This article investigates the limitations of Chat Generative Pre-trained Transformer (ChatGPT), a language model developed by OpenAI, as a study tool in dermatology. The study utilized ChatPDF, an application that integrates PDF files with ChatGPT, to ... ...

    Abstract This article investigates the limitations of Chat Generative Pre-trained Transformer (ChatGPT), a language model developed by OpenAI, as a study tool in dermatology. The study utilized ChatPDF, an application that integrates PDF files with ChatGPT, to generate American Board of Dermatology Applied Exam (ABD-AE)-style questions from continuing medical education articles from the
    Language English
    Publishing date 2023-08-18
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2747273-5
    ISSN 2168-8184
    ISSN 2168-8184
    DOI 10.7759/cureus.43717
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  8. Article ; Online: Concurrent Langerhans cell histiocytosis and acute myeloid leukemia: A rare presentation of a rare case.

    Gao, Julia L / Davis, Matthew J / Dagrosa, Alicia T / Momtahen, Shabnam

    Journal of cutaneous pathology

    2023  Volume 51, Issue 4, Page(s) 276–279

    Abstract: A 72-year-old woman with no significant past medical history was admitted to the hospital for new-onset of leukocytosis with neutropenia, anemia, and thrombocytopenia, as well as a pruritic skin eruption. She was found to have acute myeloid leukemia (AML) ...

    Abstract A 72-year-old woman with no significant past medical history was admitted to the hospital for new-onset of leukocytosis with neutropenia, anemia, and thrombocytopenia, as well as a pruritic skin eruption. She was found to have acute myeloid leukemia (AML) with myelomonocytic differentiation. Her skin eruption consisted of widespread hemorrhagic crusted papules on the scalp and trunk. A skin biopsy was performed, which revealed a proliferation of mononuclear cells in the dermis with prominent epidermotropism and positive expression of CD1a and langerin (CD207), supporting a diagnosis of Langerhans cell histiocytosis (LCH). LCH is an uncommon proliferative disorder of activated Langerhans cells, which generally presents in children. In adults, it is exceptionally infrequent. Associated malignancies and rare reports of AML developing in subsequent years after an initial presentation of LCH have been described. Here we present an unusual concurrent presentation of LCH and AML in an adult.
    MeSH term(s) Adult ; Child ; Female ; Humans ; Aged ; Leukemia, Myeloid, Acute/complications ; Histiocytosis, Langerhans-Cell/diagnosis ; Langerhans Cells/pathology ; Skin/pathology ; Scalp/pathology
    Language English
    Publishing date 2023-12-29
    Publishing country United States
    Document type Case Reports
    ZDB-ID 187078-6
    ISSN 1600-0560 ; 0303-6987
    ISSN (online) 1600-0560
    ISSN 0303-6987
    DOI 10.1111/cup.14570
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    Zs.A 1043: Show issues Location:
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  9. Article ; Online: Subcutaneous Nodule With Poliosis: An Unusual Presentation of Melanoma Ex Blue Nevus.

    Karch, Jamie L / Davis, Matthew J / Momtahen, Shabnam / Simmons, Brian J

    Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.

    2023  Volume 49, Issue 12, Page(s) 1206–1207

    MeSH term(s) Humans ; Nevus, Blue/diagnosis ; Nevus, Blue/surgery ; Skin Neoplasms/diagnosis ; Skin Neoplasms/surgery ; Melanoma/diagnosis ; Pigmentation Disorders ; Diagnosis, Differential
    Language English
    Publishing date 2023-09-18
    Publishing country United States
    Document type Case Reports ; Journal Article
    ZDB-ID 1227586-4
    ISSN 1524-4725 ; 1076-0512
    ISSN (online) 1524-4725
    ISSN 1076-0512
    DOI 10.1097/DSS.0000000000003951
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  10. Article ; Online: Utility of Allergen-Specific Patient-Directed Handouts Generated by Chat Generative Pretrained Transformer.

    Chandra, Aditi / Davis, Matthew J / Hamann, Dathan / Hamann, Carsten R

    Dermatitis : contact, atopic, occupational, drug

    2023  Volume 34, Issue 5, Page(s) 448

    MeSH term(s) Humans ; Allergens ; Patient Education as Topic ; Artificial Intelligence
    Chemical Substances Allergens
    Language English
    Publishing date 2023-05-16
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2144723-8
    ISSN 2162-5220 ; 1532-8163 ; 1710-3568
    ISSN (online) 2162-5220 ; 1532-8163
    ISSN 1710-3568
    DOI 10.1089/derm.2023.0059
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