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  1. Article: Evaluating Biological Properties of Stingless Bee Propolis.

    Lim, Jin Ru / Chua, Lee Suan / Dawood, Dawood Ali Salim

    Foods (Basel, Switzerland)

    2023  Volume 12, Issue 12

    Abstract: The aim of the present study was to determine the content of phenolics, flavonoids and tannins, as well as the biological functions of propolis extracts from the stingless bee ( ...

    Abstract The aim of the present study was to determine the content of phenolics, flavonoids and tannins, as well as the biological functions of propolis extracts from the stingless bee (
    Language English
    Publishing date 2023-06-06
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2704223-6
    ISSN 2304-8158
    ISSN 2304-8158
    DOI 10.3390/foods12122290
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Evaluating Biological Properties of Stingless Bee Propolis

    Lim, Jin Ru / Chua, Lee Suan / Dawood, Dawood Ali Salim

    Foods. 2023 June 06, v. 12, no. 12

    2023  

    Abstract: The aim of the present study was to determine the content of phenolics, flavonoids and tannins, as well as the biological functions of propolis extracts from the stingless bee (Heterotrigona itama). The raw propolis was extracted via maceration with ... ...

    Abstract The aim of the present study was to determine the content of phenolics, flavonoids and tannins, as well as the biological functions of propolis extracts from the stingless bee (Heterotrigona itama). The raw propolis was extracted via maceration with ultrasonic pretreatment in 100% water and 20% ethanol. The yield of ethanolic propolis extracts was about 1% higher than its aqueous counterpart. The colorimetric assays showed that the ethanolic propolis extract had about two times higher phenolics (17.043 mg GAE/g) and tannins (5.411 mg GAE/g), and four times higher flavonoids (0.83 mg QE/g). The higher phenolic content had enhanced the antiradical and antibacterial capacities of the ethanolic extract. The propolis extracts significantly exhibited higher antibacterial activity against gram-positive bacteria (Staphylococcus aureus) than gram-negative bacteria (Escherichia coli and Pseudomonas aeruginosa). However, aqueous extract was found to have a higher anticancer property based on the viability of lung cancer cells. No cytotoxic effect was observed on normal lung cells as the cell viability was maintained >50%, even the concentration of propolis extracts were increased up to 800 µg/mL. Different chemical compositions of propolis extract would show different bioactivities depending upon the individual applications. The high content of phenolics suggests that the propolis extract could be a natural source of bioactive ingredients for the development of innovative and functional foods.
    Keywords Escherichia coli ; Pseudomonas aeruginosa ; Staphylococcus aureus ; antibacterial properties ; antineoplastic activity ; cell viability ; colorimetry ; cytotoxicity ; ethanol ; flavonoids ; lung neoplasms ; lungs ; maceration ; phenolic compounds ; propolis ; stingless bees ; ultrasonics
    Language English
    Dates of publication 2023-0606
    Publishing place Multidisciplinary Digital Publishing Institute
    Document type Article ; Online
    ZDB-ID 2704223-6
    ISSN 2304-8158
    ISSN 2304-8158
    DOI 10.3390/foods12122290
    Database NAL-Catalogue (AGRICOLA)

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  3. Article ; Online: Solvent Fractionation and Acetone Precipitation for Crude Saponins from

    Chua, Lee Suan / Lau, Cher Haan / Chew, Chee Yung / Dawood, Dawood Ali Salim

    Molecules (Basel, Switzerland)

    2019  Volume 24, Issue 7

    Abstract: ... Eurycoma ... ...

    Abstract Eurycoma longifolia
    MeSH term(s) Acetone/chemistry ; Antineoplastic Agents, Phytogenic/chemistry ; Antineoplastic Agents, Phytogenic/isolation & purification ; Antineoplastic Agents, Phytogenic/pharmacology ; Breast Neoplasms/drug therapy ; Breast Neoplasms/metabolism ; Breast Neoplasms/pathology ; Cell Line, Tumor ; Eurycoma/chemistry ; Female ; Humans ; Saponins/chemistry ; Saponins/isolation & purification ; Saponins/pharmacology
    Chemical Substances Antineoplastic Agents, Phytogenic ; Saponins ; Acetone (1364PS73AF)
    Language English
    Publishing date 2019-04-10
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 1413402-0
    ISSN 1420-3049 ; 1431-5165 ; 1420-3049
    ISSN (online) 1420-3049
    ISSN 1431-5165 ; 1420-3049
    DOI 10.3390/molecules24071416
    Database MEDical Literature Analysis and Retrieval System OnLINE

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