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  1. Article ; Online: Endoscopic management of gastric, duodenal and rectal NETs: Position paper from the Italian Association for Neuroendocrine Tumors (Itanet), Italian Society of Gastroenterology (SIGE), Italian Society of Digestive Endoscopy (SIED).

    Panzuto, Francesco / Parodi, Maria Caterina / Esposito, Gianluca / Massironi, Sara / Fantin, Alberto / Cannizzaro, Renato / Milione, Massimo / De Angelis, Claudio Giovanni / Annibale, Bruno

    Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver

    2024  Volume 56, Issue 4, Page(s) 589–600

    Abstract: The present paper reflects the position of the Italian Association for Neuroendocrine Tumors (Itanet), the Italian Society of Gastroenterology (SIGE), and the Italian Society of Digestive Endoscopy (SIED) regarding the management of patients affected by ... ...

    Abstract The present paper reflects the position of the Italian Association for Neuroendocrine Tumors (Itanet), the Italian Society of Gastroenterology (SIGE), and the Italian Society of Digestive Endoscopy (SIED) regarding the management of patients affected by gastric, duodenal, and rectal neuroendocrine neoplasms (NENs) amenable to endoscopic treatment. The key questions discussed in this paper are summarized in Table 1. Data were extracted from the MEDLINE database through searches; expert opinions and recommendations are provided in accordance with the available scientific evidence and the authors' expertise. Recommendations are presented alongside a level of evidence and grade of recommendation based on the GRADE system. This paper specifically focuses on subgroups of NENs considered suitable for endoscopic management according to current international guidelines: i. well-differentiated gastric neuroendocrine tumors (gNET) type 1 < 2 cm and selected cases of type 3; ii. well-differentiated duodenal, non-functioning, non-ampullary NET with size < 2 cm; and well-differentiated rectal NET with size < 2 cm.
    MeSH term(s) Humans ; Neuroendocrine Tumors/pathology ; Gastroenterology ; Endoscopy, Gastrointestinal ; Stomach Neoplasms/pathology ; Italy
    Language English
    Publishing date 2024-01-11
    Publishing country Netherlands
    Document type Journal Article ; Review
    ZDB-ID 1459373-7
    ISSN 1878-3562 ; 1125-8055
    ISSN (online) 1878-3562
    ISSN 1125-8055
    DOI 10.1016/j.dld.2023.12.015
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Ki-67 assessment in pancreatic neuroendocrine tumors: is EUS-FNA still a valid ally?

    Cortegoso Valdivia, Pablo / Rizza, Stefano / De Angelis, Claudio Giovanni

    Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.

    2021  Volume 21, Issue 2, Page(s) 496–497

    MeSH term(s) Endoscopic Ultrasound-Guided Fine Needle Aspiration ; Humans ; Ki-67 Antigen/metabolism ; Neuroendocrine Tumors/diagnosis ; Neuroendocrine Tumors/metabolism ; Pancreatic Neoplasms/diagnosis ; Pancreatic Neoplasms/metabolism ; Retrospective Studies
    Chemical Substances Ki-67 Antigen
    Language English
    Publishing date 2021-02-01
    Publishing country Switzerland
    Document type Letter
    ZDB-ID 2056680-3
    ISSN 1424-3911 ; 1424-3903
    ISSN (online) 1424-3911
    ISSN 1424-3903
    DOI 10.1016/j.pan.2021.01.021
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Pancreatic leiomyosarcoma: EUS findings of an uncommon pancreatic mass (with video).

    Gesualdo, Marcantonio / Bertetti, Noemi Sara / Mortara, Umberto / Maletta, Francesca / Moro, Francesco / Sacco, Marco / Bruno, Mauro / De Angelis, Claudio Giovanni / Gaia, Silvia

    Endoscopic ultrasound

    2023  Volume 12, Issue 5, Page(s) 435–436

    Language English
    Publishing date 2023-10-23
    Publishing country China
    Document type Journal Article
    ZDB-ID 2998317-4
    ISSN 2226-7190 ; 2303-9027
    ISSN (online) 2226-7190
    ISSN 2303-9027
    DOI 10.1097/eus.0000000000000037
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Combined laparoscopic-endoscopic resection of a bleeding giant duodenal Brunner's gland hamartoma.

    Marano, Alessandra / Sacco, Marco / Rorato, Lisa Marie / Caronna, Stefania / Di Giovanni, Fabrizia / Santarelli, Mauro / De Angelis, Claudio Giovanni

    Endoscopy

    2023  Volume 55, Issue S 01, Page(s) E983–E984

    MeSH term(s) Humans ; Brunner Glands/surgery ; Duodenum ; Laparoscopy
    Language English
    Publishing date 2023-08-21
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 80120-3
    ISSN 1438-8812 ; 0013-726X
    ISSN (online) 1438-8812
    ISSN 0013-726X
    DOI 10.1055/a-2134-9639
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: Combined laparoscopic–endoscopic resection of a bleeding giant duodenal Brunner’s gland hamartoma

    Marano, Alessandra / Sacco, Marco / Rorato, Lisa Marie / Caronna, Stefania / Di Giovanni, Fabrizia / Santarelli, Mauro / De Angelis, Claudio Giovanni

    Endoscopy

    2023  Volume 55, Issue S 01, Page(s) E983–E984

    Language English
    Publishing date 2023-08-21
    Publisher Georg Thieme Verlag KG
    Publishing place Stuttgart ; New York
    Document type Article
    ZDB-ID 80120-3
    ISSN 1438-8812 ; 0013-726X
    ISSN (online) 1438-8812
    ISSN 0013-726X
    DOI 10.1055/a-2134-9639
    Database Thieme publisher's database

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  6. Article ; Online: A case of persistent iron deficiency anemia in a kidney transplant recipient.

    Sacco, Marco / Bruno, Mauro / Deabate, Maria Carla / De Angelis, Claudio Giovanni / Pennazio, Marco

    Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver

    2020  Volume 52, Issue 12, Page(s) 1517–1518

    MeSH term(s) Anemia, Iron-Deficiency/etiology ; Diabetic Nephropathies/therapy ; Humans ; Ileitis/chemically induced ; Ileum/pathology ; Kidney Transplantation/adverse effects ; Male ; Middle Aged ; Mycophenolic Acid/adverse effects ; Single-Balloon Enteroscopy ; Ulcer/pathology
    Chemical Substances Mycophenolic Acid (HU9DX48N0T)
    Language English
    Publishing date 2020-04-25
    Publishing country Netherlands
    Document type Case Reports ; Journal Article
    ZDB-ID 1459373-7
    ISSN 1878-3562 ; 1125-8055
    ISSN (online) 1878-3562
    ISSN 1125-8055
    DOI 10.1016/j.dld.2020.03.025
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: An Unusual Cause of Cholangitis.

    Cortegoso Valdivia, Pablo / Venezia, Ludovica / Rizza, Stefano / Chiusa, Luigi / De Angelis, Claudio Giovanni

    GE Portuguese journal of gastroenterology

    2019  Volume 27, Issue 1, Page(s) 56–58

    Language English
    Publishing date 2019-06-05
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2835774-7
    ISSN 2387-1954 ; 2341-4545
    ISSN (online) 2387-1954
    ISSN 2341-4545
    DOI 10.1159/000500209
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article: The Endoscopic Retrograde Cholangiopancreatography and Endoscopic Ultrasound Connection: Unity Is Strength, or the Endoscopic Ultrasonography Retrograde Cholangiopancreatography Concept.

    De Angelis, Claudio Giovanni / Dall'Amico, Eleonora / Staiano, Maria Teresa / Gesualdo, Marcantonio / Bruno, Mauro / Gaia, Silvia / Sacco, Marco / Fimiano, Federica / Mauriello, Anna / Dibitetto, Simone / Canalis, Chiara / Stasio, Rosa Claudia / Caneglias, Alessandro / Mediati, Federica / Rocca, Rodolfo

    Diagnostics (Basel, Switzerland)

    2023  Volume 13, Issue 20

    Abstract: Endoscopic ultrasound (EUS) and endoscopic retrograde cholangiopancreatography (ERCP) are both crucial for the endoscopic management of biliopancreatic diseases: the combination of their diagnostic and therapeutic potential is useful in many clinical ... ...

    Abstract Endoscopic ultrasound (EUS) and endoscopic retrograde cholangiopancreatography (ERCP) are both crucial for the endoscopic management of biliopancreatic diseases: the combination of their diagnostic and therapeutic potential is useful in many clinical scenarios, such as indeterminate biliary stenosis, biliary stones, chronic pancreatitis and biliary and pancreatic malignancies. This natural and evident convergence between EUS and ERCP, which by 2006 we were calling the "Endoscopic ultrasonography retrograde colangiopancreatography (EURCP) concept", has become a hot topic in the last years, together with the implementation of the therapeutic possibilities of EUS (from EUS-guided necrosectomy to gastro-entero anastomoses) and with the return of ERCP to its original diagnostic purpose thanks to ancillary techniques (extraductal ultrasound (EDUS), intraductal ultrasound (IDUS), cholangiopancreatoscopy with biopsies and probe-based confocal laser endomicroscopy (pCLE)). In this literary review, we retraced the recent history of EUS and ERCP, reported examples of the clinical applicability of the EURCP concept and explored the option of performing the two procedures in only one endoscopic session, with its positive implications for the patient, the endoscopist and the health care system. In the last few years, we also evaluated the possibility of combining EUS and ERCP into a single endoscopic instrument in a single step, but certain obstacles surrounding this approach remain.
    Language English
    Publishing date 2023-10-20
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2662336-5
    ISSN 2075-4418
    ISSN 2075-4418
    DOI 10.3390/diagnostics13203265
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article: Impact of Macroscopic On-Site Evaluation (MOSE) on Accuracy of Endoscopic Ultrasound-Guided Fine-Needle Biopsy (EUS-FNB) of Pancreatic and Extrapancreatic Solid Lesions: A Prospective Study.

    Gaia, Silvia / Rizza, Stefano / Bruno, Mauro / Ribaldone, Davide Giuseppe / Maletta, Francesca / Sacco, Marco / Pacchioni, Donatella / Rizzi, Felice / Saracco, Giorgio Maria / Fagoonee, Sharmila / De Angelis, Claudio Giovanni

    Diagnostics (Basel, Switzerland)

    2022  Volume 12, Issue 2

    Abstract: This is a prospective and comparative study including 76 consecutive patients performing EUS-FNB for pancreatic and extrapancreatic solid lesions, randomized by alternate allocation to macroscopic on-site evaluation (MOSE) (40 patients) or to a ... ...

    Abstract This is a prospective and comparative study including 76 consecutive patients performing EUS-FNB for pancreatic and extrapancreatic solid lesions, randomized by alternate allocation to macroscopic on-site evaluation (MOSE) (40 patients) or to a conventional technique (40 patients), with three passes each. MOSE samples were differentiated into score 0: no visible material, score 1: only necrotic or haematic material, score 2: white core tissue ≤ 2 mm, or score 3: white core tissue > 2 mm. The conventional technique consisted in pushing all the needle content into a test tube for evaluation by the pathologist. In both groups, a 22-25 Gauge Franseen-tip needle (Acquire, Boston Scientific Co., Natick, MA, USA) was used. The study evaluated the diagnostic accuracy and adequacy of MOSE compared to the conventional technique and whether MOSE could optimize the number of passes during EUS-FNB.
    Language English
    Publishing date 2022-02-07
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2662336-5
    ISSN 2075-4418
    ISSN 2075-4418
    DOI 10.3390/diagnostics12020428
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article: Assessment of the Risk of Nodal Involvement in Rectal Neuroendocrine Neoplasms: The NOVARA Score, a Multicentre Retrospective Study.

    Ricci, Angela Dalia / Pusceddu, Sara / Panzuto, Francesco / Gelsomino, Fabio / Massironi, Sara / De Angelis, Claudio Giovanni / Modica, Roberta / Ricco, Gianluca / Torchio, Martina / Rinzivillo, Maria / Prinzi, Natalie / Rizzi, Felice / Lamberti, Giuseppe / Campana, Davide

    Journal of clinical medicine

    2022  Volume 11, Issue 3

    Abstract: Rectal neuroendocrine tumors (r-NETs) are rare tumors with overall good prognosis after complete resection. However, there is no consensus on the extension of lymphadenectomy or regarding contraindications to extensive resection. In this study, we aim to ...

    Abstract Rectal neuroendocrine tumors (r-NETs) are rare tumors with overall good prognosis after complete resection. However, there is no consensus on the extension of lymphadenectomy or regarding contraindications to extensive resection. In this study, we aim to identify predictive factors that correlate with nodal metastasis in patients affected by G1-G2 r-NETs. A retrospective analysis of G1-G2 r-NETs patients from eight tertiary Italian centers was performed. From January 1990 to January 2020, 210 patients were considered and 199 were included in the analysis. The data for nodal status were available for 159 cases. The nodal involvement rate was 9%. A receiver operating characteristic (ROC) curve analysis was performed to identify the diameter (>11.5 mm) and Ki-67 (3.5%), respectively, as cutoff values to predict nodal involvement. In a multivariate analysis, diameter > 11.5 mm and vascular infiltration were independently correlated with nodal involvement. A risk scoring system was constructed using these two predictive factors. Tumor size and vascular invasion are predictors of nodal involvement. In addition, tumor size > 11.5 mm is used as a driving parameter of better-tailored treatment during pre-operative assessment. Data from prospective studies are needed to validate these results and to guide decision-making in r-NETs patients in clinical practice.
    Language English
    Publishing date 2022-01-28
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2662592-1
    ISSN 2077-0383
    ISSN 2077-0383
    DOI 10.3390/jcm11030713
    Database MEDical Literature Analysis and Retrieval System OnLINE

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