Article ; Online: Superwarfarin poisoning: challenges still remain.
BMJ case reports
2022 Volume 15, Issue 5
Abstract: Superwarfarin (long-acting anticoagulant rodenticide) poisoning should be suspected in unexplained bleeding with prolonged prothrombin time, especially in the absence of another explanation. Diagnosis and treatment of this intoxication remain a challenge ...
| Abstract | Superwarfarin (long-acting anticoagulant rodenticide) poisoning should be suspected in unexplained bleeding with prolonged prothrombin time, especially in the absence of another explanation. Diagnosis and treatment of this intoxication remain a challenge as the direct analysis of superwarfarin in serum is not always possible. Therefore, toxin bioavailability remains unknown and close monitoring and treatment for long periods are required to avoid serious bleeding complications. Here, we discuss a case of suspected superwarfarin poisoning to highlight the challenges in early diagnosis and the challenges we encountered in treatment management and ensuring compliance for long periods. |
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| MeSH term(s) | 4-Hydroxycoumarins ; Anticoagulants ; Blood Coagulation Disorders/chemically induced ; Humans ; Poisoning/therapy ; Rodenticides |
| Chemical Substances | 4-Hydroxycoumarins ; Anticoagulants ; Rodenticides ; bromfenacoum (A25P3CP5S7) |
| Language | English |
| Publishing date | 2022-05-18 |
| Publishing country | England |
| Document type | Case Reports ; Journal Article |
| ISSN | 1757-790X |
| ISSN (online) | 1757-790X |
| DOI | 10.1136/bcr-2021-248385 |
| Database | MEDical Literature Analysis and Retrieval System OnLINE |
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