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  1. Article ; Online: Mechanical and Oral Antibiotic Bowel Preparation in Elective Rectal Resection.

    Lacy, Antonio M / de Lacy, F Borja

    JAMA surgery

    2024  

    Language English
    Publishing date 2024-03-20
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2701841-6
    ISSN 2168-6262 ; 2168-6254
    ISSN (online) 2168-6262
    ISSN 2168-6254
    DOI 10.1001/jamasurg.2024.0174
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  2. Article: Education and Training in Transanal Endoscopic Surgery and Transanal Total Mesorectal Excision.

    Keller, Deborah S / de Lacy, F Borja / Hompes, Roel

    Clinics in colon and rectal surgery

    2021  Volume 34, Issue 3, Page(s) 163–171

    Abstract: There is a paradigm shift in surgical training, and new tool and technology are being used to facilitate mastery of the content and technical skills. The transanal procedures for rectal cancer-transanal endoscopic surgery (TES) and transanal total ... ...

    Abstract There is a paradigm shift in surgical training, and new tool and technology are being used to facilitate mastery of the content and technical skills. The transanal procedures for rectal cancer-transanal endoscopic surgery (TES) and transanal total mesorectal excision (TaTME)-have a distinct learning curve for competence in the procedures, and require special training for familiarity with the "bottom-up" anatomy, procedural risks, and managing complex cases. These procedures have been models for structured education and training, using multimodal tools, to ensure safe implementation of TES and TaTME into clinical practice. The goal of this work was to review the current state of surgical education, the introduction and learning curve of the TES and TaTME procedures, and the established and future models for education of the transanal procedures for rectal cancer.
    Language English
    Publishing date 2021-03-31
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 2048635-2
    ISSN 1531-0043
    ISSN 1531-0043
    DOI 10.1055/s-0040-1718682
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 3931: Show issues Location:
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  3. Article ; Online: Response to the Comment on "Neyman's Bias in Online Voluntary Databases!"

    Roodbeen, Sapho Xenia / de Lacy, F B / Hompes, Roel

    Annals of surgery

    2020  Volume 274, Issue 6, Page(s) e702–e703

    MeSH term(s) Bias ; Databases, Factual ; Humans ; Models, Statistical
    Language English
    Publishing date 2020-04-22
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 340-2
    ISSN 1528-1140 ; 0003-4932
    ISSN (online) 1528-1140
    ISSN 0003-4932
    DOI 10.1097/SLA.0000000000003898
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  4. Article: Education and Training in Transanal Endoscopic Surgery and Transanal Total Mesorectal Excision

    Keller, Deborah S. / de Lacy, F. Borja / Hompes, Roel

    Clinics in Colon and Rectal Surgery

    (Education and Training in Minimally Invasive and Robotic Approaches to Colorectal Disease)

    2021  Volume 34, Issue 03, Page(s) 163–171

    Abstract: There is a paradigm shift in surgical training, and new tool and technology are being used to facilitate mastery of the content and technical skills. The transanal procedures for rectal cancer—transanal endoscopic surgery (TES) and transanal total ... ...

    Series title Education and Training in Minimally Invasive and Robotic Approaches to Colorectal Disease
    Abstract There is a paradigm shift in surgical training, and new tool and technology are being used to facilitate mastery of the content and technical skills. The transanal procedures for rectal cancer—transanal endoscopic surgery (TES) and transanal total mesorectal excision (TaTME)—have a distinct learning curve for competence in the procedures, and require special training for familiarity with the “bottom-up” anatomy, procedural risks, and managing complex cases. These procedures have been models for structured education and training, using multimodal tools, to ensure safe implementation of TES and TaTME into clinical practice. The goal of this work was to review the current state of surgical education, the introduction and learning curve of the TES and TaTME procedures, and the established and future models for education of the transanal procedures for rectal cancer.
    Keywords rectal cancer ; transanal minimally invasive surgery (TAMIS) ; transanal total mesorectal excision (TaTME) ; surgical education ; surgical simulation ; virtual reality (VR)
    Language English
    Publishing date 2021-03-31
    Publisher Thieme Medical Publishers, Inc.
    Publishing place Stuttgart ; New York
    Document type Article
    ZDB-ID 2048635-2
    ISSN 1530-9681 ; 1531-0043
    ISSN (online) 1530-9681
    ISSN 1531-0043
    DOI 10.1055/s-0040-1718682
    Database Thieme publisher's database

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    Zs.A 3931: Show issues Location:
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  5. Article ; Online: Fluorescent-guided surgery with quantitative indocyanine green assessment - a video vignette.

    González-Abós, C / de Lacy, F B / Lacy, A M

    Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland

    2020  Volume 22, Issue 10, Page(s) 1466

    MeSH term(s) Coloring Agents ; Humans ; Indocyanine Green
    Chemical Substances Coloring Agents ; Indocyanine Green (IX6J1063HV)
    Language English
    Publishing date 2020-05-15
    Publishing country England
    Document type Letter ; Video-Audio Media
    ZDB-ID 1440017-0
    ISSN 1463-1318 ; 1462-8910
    ISSN (online) 1463-1318
    ISSN 1462-8910
    DOI 10.1111/codi.15097
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    Zs.A 5799: Show issues Location:
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  6. Article ; Online: Considerations for transanal total mesorectal excision (TaTME) use during the COVID-19 pandemic.

    Lacy, A M / De Lacy, F B / Balibrea, J M

    The British journal of surgery

    2020  Volume 107, Issue 7, Page(s) e203

    MeSH term(s) Betacoronavirus ; COVID-19 ; Coronavirus Infections/complications ; Coronavirus Infections/prevention & control ; Coronavirus Infections/transmission ; Humans ; Infectious Disease Transmission, Patient-to-Professional/prevention & control ; Pandemics/prevention & control ; Pneumonia, Viral/complications ; Pneumonia, Viral/prevention & control ; Pneumonia, Viral/transmission ; Proctectomy/methods ; Rectal Neoplasms/surgery ; Rectal Neoplasms/virology ; SARS-CoV-2 ; Transanal Endoscopic Surgery/methods
    Keywords covid19
    Language English
    Publishing date 2020-05-08
    Publishing country England
    Document type Letter
    ZDB-ID 2985-3
    ISSN 1365-2168 ; 0263-1202 ; 0007-1323 ; 1355-7688
    ISSN (online) 1365-2168
    ISSN 0263-1202 ; 0007-1323 ; 1355-7688
    DOI 10.1002/bjs.11685
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  7. Article ; Online: Endoscopic vacuum therapy and early surgical closure after pelvic anastomotic leak: meta-analysis of bowel continuity rates.

    de Lacy, F Borja / Talboom, Kevin / Roodbeen, Sapho X / Blok, Robin / Curell, Anna / Tanis, Pieter J / Bemelman, Wilhelmus A / Hompes, Roel

    The British journal of surgery

    2022  Volume 109, Issue 9, Page(s) 822–831

    Abstract: Background: Endoscopic vacuum therapy (EVT) with or without early surgical closure (ESC) is considered an effective option in the management of pelvic anastomotic leakage. This meta-analysis evaluated the effectiveness of EVT in terms of stoma reversal ... ...

    Abstract Background: Endoscopic vacuum therapy (EVT) with or without early surgical closure (ESC) is considered an effective option in the management of pelvic anastomotic leakage. This meta-analysis evaluated the effectiveness of EVT in terms of stoma reversal rate and the added value of ESC.
    Methods: A systematic search of PubMed, MEDLINE, and the Cochrane Library was conducted in November 2021 to identify articles on EVT in adult patients with pelvic anastomotic leakage. The primary outcome was restored continuity rate. Following PRISMA guidelines, a meta-analysis was undertaken using a random-effects model.
    Results: Twenty-nine studies were included, accounting for 827 patients with leakage who underwent EVT. There was large heterogeneity between studies in design and reported outcomes, and a high risk of bias. The overall weighted mean restored continuity rate was 66.8 (95 per cent c.i. 58.8 to 73.9) per cent. In patients undergoing EVT with ESC, the calculated restored continuity rate was 82 per cent (95 per cent c.i. 50.1 to 95.4) as compared to 64.7 per cent (95 per cent c.i. 55.7 to 72.7) after EVT without ESC. The mean number of sponge exchanges was 4 (95 per cent c.i. 2.7 to 4.6) and 9.8 (95 per cent c.i. 7.3 to 12.3), respectively. Sensitivity analysis showed a restored continuity rate of 81 per cent (95 per cent c.i. 55.8 to 99.5) for benign disease, 69.0 per cent (95 per cent c.i. 57.3 to 78.7) for colorectal cancer, and 65 per cent (95 per cent c.i. 48.8 to 79.1) if neoadjuvant radiotherapy was given.
    Conclusion: EVT is associated with satisfactory stoma reversal rates that may be improved if it is combined with ESC.
    MeSH term(s) Adult ; Anastomosis, Surgical ; Anastomotic Leak/etiology ; Anastomotic Leak/surgery ; Endoscopy ; Humans ; Negative-Pressure Wound Therapy/adverse effects ; Negative-Pressure Wound Therapy/methods ; Pelvis/surgery
    Language English
    Publishing date 2022-05-31
    Publishing country England
    Document type Journal Article ; Meta-Analysis ; Systematic Review
    ZDB-ID 2985-3
    ISSN 1365-2168 ; 0263-1202 ; 0007-1323 ; 1355-7688
    ISSN (online) 1365-2168
    ISSN 0263-1202 ; 0007-1323 ; 1355-7688
    DOI 10.1093/bjs/znac158
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  8. Article ; Online: Comment on: Norwegian moratorium on transanal total mesorectal excision.

    Lacy, A M / Nogueira, S T / de Lacy, F Borja

    The British journal of surgery

    2019  Volume 106, Issue 13, Page(s) 1855

    MeSH term(s) Humans ; Norway ; Rectal Neoplasms ; Transanal Endoscopic Surgery
    Language English
    Publishing date 2019-12-04
    Publishing country England
    Document type Letter ; Comment
    ZDB-ID 2985-3
    ISSN 1365-2168 ; 0263-1202 ; 0007-1323 ; 1355-7688
    ISSN (online) 1365-2168
    ISSN 0263-1202 ; 0007-1323 ; 1355-7688
    DOI 10.1002/bjs.11375
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  9. Article ; Online: Comparison of proactive and conventional treatment of anastomotic leakage in rectal cancer surgery: a multicentre retrospective cohort series.

    Talboom, K / Greijdanus, N G / Brinkman, N / Blok, R D / Roodbeen, S X / Ponsioen, C Y / Tanis, P J / Bemelman, W A / Cunningham, C / de Lacy, F B / Hompes, Roel

    Techniques in coloproctology

    2023  Volume 27, Issue 11, Page(s) 1099–1108

    Abstract: Purpose: Comparative studies on efficacy of treatment strategies for anastomotic leakage (AL) after low anterior resection (LAR) are almost non-existent. This study aimed to compare different proactive and conservative treatment approaches for AL after ... ...

    Abstract Purpose: Comparative studies on efficacy of treatment strategies for anastomotic leakage (AL) after low anterior resection (LAR) are almost non-existent. This study aimed to compare different proactive and conservative treatment approaches for AL after LAR.
    Methods: This retrospective cohort study included all patients with AL after LAR in three university hospitals. Different treatment approaches were compared, including a pairwise comparison of conventional treatment and endoscopic vacuum-assisted surgical closure (EVASC). Primary outcomes were healed and functional anastomosis rates at end of follow-up.
    Results: Overall, 103 patients were included, of which 59 underwent conventional treatment and 23 EVASC. Median number of reinterventions was 1 after conventional treatment, compared to 7 after EVASC (p < 0.01). Median follow-up was 39 and 25 months, respectively. Healed anastomosis rate was 61% after conventional treatment, compared to 78% after EVASC (p = 0.139). Functional anastomosis rate was higher after EVASC, compared to conventional treatment (78% vs. 54%, p = 0.045). Early initiation of EVASC in the first week after primary surgery resulted in better functional anastomosis rate compared to later initiation (100% vs. 55%, p = 0.008).
    Conclusion: Proactive treatment of AL consisting of EVASC resulted in improved healed and functional anastomosis rates for AL after LAR for rectal cancer, compared to conventional treatment. If EVASC was initiated within the first week after index surgery, a 100% functional anastomosis rate was achievable.
    Language English
    Publishing date 2023-05-22
    Publishing country Italy
    Document type Journal Article
    ZDB-ID 2083309-X
    ISSN 1128-045X ; 1123-6337
    ISSN (online) 1128-045X
    ISSN 1123-6337
    DOI 10.1007/s10151-023-02808-z
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    Zs.A 5842: Show issues Location:
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  10. Article ; Online: Exposure to virtual reality as a tool to reduce peri-operative anxiety in patients undergoing colorectal cancer surgery: a single-center prospective randomized clinical trial.

    Turrado, Víctor / Guzmán, Yoelimar / Jiménez-Lillo, Julio / Villegas, Eduardo / de Lacy, Francisco B / Blanch, Jordi / Balibrea, José M / Lacy, Antonio

    Surgical endoscopy

    2021  Volume 35, Issue 7, Page(s) 4042–4047

    Abstract: Background: More than 60% of patients who undergo surgery for colorectal cancer experience anxiety at some point during the perioperative period. In addition to the obvious impact on the experience of the therapeutic process, the presence of anxiety has ...

    Abstract Background: More than 60% of patients who undergo surgery for colorectal cancer experience anxiety at some point during the perioperative period. In addition to the obvious impact on the experience of the therapeutic process, the presence of anxiety has also been associated with the appearance of complications. Virtual reality could reduce it by simulating the controlled exposure of the patient to the conscious part of the surgical process.
    Methods: Single-center randomized clinical trial (NCT04058600) in which patients who were to undergo surgery for colorectal cancer and who had not previously undergone surgery as adults were exposed, prior to hospital admission, to virtual reality software in which all perioperative phases in which the patient is awake, from admission to discharge, were recreated. The main objective was to determine the presence of pre- and post-exposure anxiety using the validated State-Trait Anxiety Inventory Scale (STAI-S) and Hospital Anxiety and Depression Scale (HADS).
    Results: A total of 126 patients were recruited (58 exposed, 68 unexposed). There were no differences between the groups in terms of age, gender, anesthetic risk, type of surgery. or levels of preoperative anxiety or depression. After exposure, all anxiety/depression rating scales decreased significantly.
    Conclusions: The use of simulation using virtual reality can reduce perioperative anxiety in patients undergoing surgery for colorectal cancer.
    MeSH term(s) Adult ; Anxiety/etiology ; Anxiety/prevention & control ; Colorectal Neoplasms/surgery ; Digestive System Surgical Procedures ; Humans ; Prospective Studies ; Virtual Reality
    Language English
    Publishing date 2021-03-08
    Publishing country Germany
    Document type Journal Article ; Randomized Controlled Trial
    ZDB-ID 639039-0
    ISSN 1432-2218 ; 0930-2794
    ISSN (online) 1432-2218
    ISSN 0930-2794
    DOI 10.1007/s00464-021-08407-z
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