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  1. Article ; Online: An unusual case of genital filariasis of the testicular tunics in an Italian patient.

    Fassari, Alessia / Polistena, Andrea / De Toma, Giorgio / Fiori, Enrico

    Annals of Saudi medicine

    2021  Volume 41, Issue 3, Page(s) 186–189

    Abstract: At least 27 million men present with urogenital manifestations of genital filariasis (GF). Although there is a large burden of GF in residents in endemic regions, infection in short-term travellers and in non-endemic areas is rare. We report the case of ... ...

    Abstract At least 27 million men present with urogenital manifestations of genital filariasis (GF). Although there is a large burden of GF in residents in endemic regions, infection in short-term travellers and in non-endemic areas is rare. We report the case of a 75-year-old Italian man referred to our institution for a testicular discomfort. Clinical examination and ultrasound detected a mass of 40×18 mm in the scrotum without signs of varicocele, hydrocele and testicular or epididymal abnormalities. After ineffective medical treatment, the patient underwent surgical excision. Histology demonstrated filarial granuloma with thick cuticles pathognomonic of an adult worm in the testicular tunics. Surgery has a fundamental role in localized cases of GF to remove nematodes from the fibrotic nodules. The present manuscript describes a singular case of GF observed in Italy in a non-immigrant patient with evidence of remnants of an adult worm in the testicular tunics. SIMILAR CASES PUBLISHED: 11.
    MeSH term(s) Aged ; Filariasis/diagnosis ; Genitalia ; Humans ; Italy ; Male ; Scrotum/diagnostic imaging ; Ultrasonography
    Language English
    Publishing date 2021-06-01
    Publishing country Saudi Arabia
    Document type Case Reports ; Journal Article
    ZDB-ID 639014-6
    ISSN 0975-4466 ; 0256-4947
    ISSN (online) 0975-4466
    ISSN 0256-4947
    DOI 10.5144/0256-4947.2021.186
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  2. Article ; Online: A Pilot Study on an Integrated Service Based on Wearable Textile Platforms to promote Workers Wellness at Workplace.

    De Toma, G / Pacelli, M / Paradiso, R / Victoria, A R / Saunder, M / Cuervo, G

    Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference

    2019  Volume 2019, Page(s) 1757–1760

    Abstract: This paper describes a study performed in the frame of Wearables project and reports preliminary results. Objective of the study was the implementation of an integrated service finalized to increase employees' well-being through the investigation on the ... ...

    Abstract This paper describes a study performed in the frame of Wearables project and reports preliminary results. Objective of the study was the implementation of an integrated service finalized to increase employees' well-being through the investigation on the correlation between daily working activity and the observed physical parameters. The project monitored 28 volunteers employed in the field of waste collection (at the Amey's contract with Wolverhampton City Council), for a total of 275 data acquisition sessions. The study has been performed using sensing textiles, to collect objective work-correlated parameters during daily activity, aiming at the acquisition of objective indicators for an improved wellbeing. Physical parameters like heart rate, energy expenditure and heart rate activity-zones distribution have been evaluated from data acquired during normal working activity. The service produced encouraging results both in terms of monitoring individual subjects and in identifying trends correlated to different roles or tasks covered by workers. Also in term of usability and acceptability the system showed interesting potentialities, proving how wearable technologies can trigger innovative approaches and open new prospective in the growing field of workplace wellness.
    MeSH term(s) Energy Metabolism ; Exercise ; Health Promotion ; Heart Rate ; Humans ; Pilot Projects ; Prospective Studies ; Textiles ; Wearable Electronic Devices ; Workplace
    Language English
    Publishing date 2019-12-30
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ISSN 2694-0604
    ISSN (online) 2694-0604
    DOI 10.1109/EMBC.2019.8857690
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Lorenzo Capussotti (1947-2014).

    De Toma, Giorgio

    Updates in surgery

    2014  Volume 66, Issue 3, Page(s) 171

    MeSH term(s) General Surgery/history ; History, 20th Century ; History, 21st Century ; Italy
    Language English
    Publishing date 2014-09
    Publishing country Italy
    Document type Biography ; Historical Article ; Journal Article
    ZDB-ID 2572692-4
    ISSN 2038-3312 ; 2038-131X
    ISSN (online) 2038-3312
    ISSN 2038-131X
    DOI 10.1007/s13304-014-0263-2
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  4. Article ; Online: Criticism of learning curve in laparoscopic adrenalectomy: a systematic review.

    Tarallo, M / Crocetti, D / Fiori, E / Sapienza, P / Letizia, C / De Toma, G / Cavallaro, G

    La Clinica terapeutica

    2020  Volume 171, Issue 2, Page(s) e178–e182

    Abstract: Background: Laparoscopic adrenalectomy (LA) has become the treatment of choice for benign adrenal lesions. Lateral Transperitoneal Laparoscopic Adrenalectomy (LTLA) is considered the gold standard. The number of LTLAs a surgeon must perform, in order to ...

    Abstract Background: Laparoscopic adrenalectomy (LA) has become the treatment of choice for benign adrenal lesions. Lateral Transperitoneal Laparoscopic Adrenalectomy (LTLA) is considered the gold standard. The number of LTLAs a surgeon must perform, in order to complete his learning curve, is not well defined in Literature. Moreover, the few papers dealing with the learning curve for LTLAs show controversial results and consider different evaluation parameters.
    Methods: The systematic review has been carried out according to PRISMA statement. The literature search included PubMed and Scopus database. Hand searching of reference lists of previous review articles and relevant studies was also performed. The search string was "learning curve AND laparoscopic adrenalectomy".
    Results: A total of 9 papers met the inclusion criteria out of 94 non duplicate citations. The aim of this systematic review is to provide a multidimensional evaluation by bringing into focus evaluation parameters of surgical performance, (operative time, intraoperative complications, conversion rate and blood loss), factors related to patient's pathology (side, size, adrenal pathology) and surgeon-specific properties.
    Conclusions: Operative time, intraoperative bleeding, intraoperative complications and conversion rate are the main parameters that have been considered for the achievement of learning curve, and for each there are discrepancies, mainly due to the relative rarity of adrenal tumors, and so for difficulties in obtaining approper analysis that could establish an effective learning curve. So, further evaluations in larger experience are needed.
    MeSH term(s) Adrenal Gland Neoplasms/surgery ; Adrenalectomy/education ; Humans ; Intraoperative Complications ; Laparoscopy/education ; Laparoscopy/methods ; Learning Curve ; Length of Stay ; Operative Time
    Language English
    Publishing date 2020-03-05
    Publishing country Italy
    Document type Journal Article ; Systematic Review
    ZDB-ID 123320-8
    ISSN 1972-6007 ; 0009-9074
    ISSN (online) 1972-6007
    ISSN 0009-9074
    DOI 10.7417/CT.2020.2209
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  5. Article ; Online: Current role of open surgery in adrenal tumors.

    Chiappini, A / Frattolillo, G / Paradiso, G / De Gori, A / Scarano Catanazaro, V / Avantifiori, R / Fiori, E / De Toma, G

    Il Giornale di chirurgia

    2020  Volume 41, Issue 1, Page(s) 79–83

    Abstract: Aim: The aim of this retrospective evaluation is to assess the current role of open adrenalectomy, in particular in cases of adrenocortical carcinoma (ACC).: Materials and methods: From January 2009 to May 2019, 26 open out of 233 adrenalectomies ... ...

    Abstract Aim: The aim of this retrospective evaluation is to assess the current role of open adrenalectomy, in particular in cases of adrenocortical carcinoma (ACC).
    Materials and methods: From January 2009 to May 2019, 26 open out of 233 adrenalectomies were performed in our Academic Department. Open adrenalectomy was performed by the anterior approach. A midline abdominal incision or a subcostal surgical incision was used to reach the peritoneal cavity. The resection was defined R0 if the margins of the sample were negative for malignancy.
    Results: Open adrenalectomy was performed in 26 patients: 10 men and 16 women with a mean age of 61±25.3 years and a mean BMI of 28.4±2.9. The right adrenal gland was removed in 15 cases Romaand the left in 11 cases.We reported 18 diagnosis of malignant pathology. The other diagnosis concerned 5 cases of pheochromocytoma, 1 case of Cushing's disease and 2 cases of hyperaldosteronism. Mean tumor size was 7.7±5.5. Mean operative time was 160 min (range=110-205 minutes). Mean postoperative stay was 7±2 days. Only 3 (10%) patient showed postoperative grade II complications, according to Clavien-Dindo classification. Midline abdominal incision was used in 18 patients, subcostalsurgical incision in 5 patients and bilateral subcostal surgical incision in 3 patients. 3 right nephrectomy was necessary to remove the entire tumor mass. An en bloc R0 tumor resection was accomplished in all cases.There was no intra and perioperative mortality. All patients recovered well from surgery. The mean follow-up period was 15 (range=6-48) months.
    Conclusion: In conclusion, our retrospective study points out the role of open adrenalectomy as the treatment of choice in selected cases with known or suspected malignant adrenal tumors and with size greater than 12 cm.
    MeSH term(s) Abdominal Wall/surgery ; Adrenal Cortex Neoplasms/pathology ; Adrenal Cortex Neoplasms/surgery ; Adrenal Gland Neoplasms/pathology ; Adrenal Gland Neoplasms/surgery ; Adrenalectomy/adverse effects ; Adrenalectomy/methods ; Adrenalectomy/statistics & numerical data ; Adrenocortical Carcinoma/pathology ; Adrenocortical Carcinoma/surgery ; Cushing Syndrome/surgery ; Female ; Follow-Up Studies ; Humans ; Hyperaldosteronism/surgery ; Male ; Margins of Excision ; Middle Aged ; Nephrectomy/statistics & numerical data ; Operative Time ; Pheochromocytoma/surgery ; Postoperative Complications/classification ; Retrospective Studies ; Surgical Wound ; Tumor Burden
    Language English
    Publishing date 2020-02-09
    Publishing country Italy
    Document type Journal Article
    ZDB-ID 605974-0
    ISSN 1971-145X ; 0391-9005
    ISSN (online) 1971-145X
    ISSN 0391-9005
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  6. Article ; Online: The role of laparoscopic surgery in isolated adrenal metastasis: our personal experience.

    Frattolillo, G / Paradiso, G / Scarano Catanazaro, V / Giordano, L / Avantifiori, R / D'Ermo, G / Letizia, C / De Toma, G

    Il Giornale di chirurgia

    2020  Volume 41, Issue 1, Page(s) 46–490

    Abstract: Background: Over the past 25 years, mini-invasive adrenalectomy has become the treatment of choice for most adrenal diseases, and even adrenal malignancies in selected cases. The aim of this retrospective evaluation is to assess the effectiveness of ... ...

    Abstract Background: Over the past 25 years, mini-invasive adrenalectomy has become the treatment of choice for most adrenal diseases, and even adrenal malignancies in selected cases. The aim of this retrospective evaluation is to assess the effectiveness of laparoscopic adrenalectomy as a treatment of choice for adrenal metastases.
    Methods: From 2008 to 2018, 207 laparoscopic adrenalectomies have been performed in our Department of Surgery. Among these, in 12 cases the indication to adrenalectomy was metastatic adrenal lesion.
    Results: The right adrenal gland was removed in 8 cases and the left adrenal gland in 4 cases. A complete resection (R0) was achieved in all patients. The median operative time was 130.6 ± 23.3 min. The median postoperative hospitalization was 3.5±2.0 days. Only one patient showed postoperative grade II complications, according to Clavien-Dindo classification. All patients underwent follow-up at 6-12-18 months without showing disease recurrence. There was no intra and perioperative mortality. Conversion to laparotomic surgery has never been performed. Mean tumor size was 2.4 cm ±1.6 cm.
    Conclusions: Laparoscopic adrenalectomy for metastasis permits to achieve similar results to the open approach in term of oncological outcomes, but gaining in terms of postoperative hospitalization, intra and post-operative complications as well a greater patient compliance.
    MeSH term(s) Adrenal Gland Neoplasms/pathology ; Adrenal Gland Neoplasms/secondary ; Adrenal Gland Neoplasms/surgery ; Adrenalectomy/methods ; Adrenalectomy/statistics & numerical data ; Conversion to Open Surgery ; Female ; Humans ; Laparoscopy/statistics & numerical data ; Length of Stay ; Male ; Operative Time ; Retrospective Studies ; Tumor Burden
    Language English
    Publishing date 2020-02-09
    Publishing country Italy
    Document type Journal Article
    ZDB-ID 605974-0
    ISSN 1971-145X ; 0391-9005
    ISSN (online) 1971-145X
    ISSN 0391-9005
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  7. Article ; Online: Z-entry technique reduces the risk of trocar-site hernias in obese patients.

    Cisano, C / Sapienza, P / Crocetti, D / de Toma, G

    Annals of the Royal College of Surgeons of England

    2016  Volume 98, Issue 5, Page(s) 340–341

    MeSH term(s) Humans ; Incisional Hernia/epidemiology ; Incisional Hernia/etiology ; Incisional Hernia/prevention & control ; Laparoscopy/adverse effects ; Laparoscopy/instrumentation ; Laparoscopy/methods ; Obesity/complications ; Obesity/epidemiology ; Surgical Instruments/adverse effects
    Language English
    Publishing date 2016-05
    Publishing country England
    Document type Journal Article
    ZDB-ID 80044-2
    ISSN 1478-7083 ; 0035-8843
    ISSN (online) 1478-7083
    ISSN 0035-8843
    DOI 10.1308/rcsann.2016.0114
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  8. Article ; Online: Preservation of left colic artery with lymph node dissection of IMA root during laparoscopic surgery for rectosigmoid cancer. Results of a retrospective analysis.

    Crocetti, D / Cavallaro, G / Tarallo, M R / Chiappini, A / Polistena, A / Sapienza, P / Fiori, E / De Toma, G

    La Clinica terapeutica

    2019  Volume 170, Issue 2, Page(s) e124–e128

    Abstract: Background: During sigmoid or rectal cancer surgery, dissection of lymph-nodes at the origin of inferior mesenteric artery is mandatory. Nevertheless, ligation of the origin of IMA should compromise blood supply to left colon and affect anastomosis. The ...

    Abstract Background: During sigmoid or rectal cancer surgery, dissection of lymph-nodes at the origin of inferior mesenteric artery is mandatory. Nevertheless, ligation of the origin of IMA should compromise blood supply to left colon and affect anastomosis. The aim of this retrospective evaluation is to compare high IMA ligation and low IMA ligation with preservation of LCA and skeletonization of the origin of IMA during laparoscopic colorectal resection.
    Methods: All 120 patients included were affected by clinically M-0 sigmoid or rectal cancer. A laparoscopic colorectal resection with low or high ligature of IMA was performed. Low ligation was carried out with lymphadenectomy of the arterial root. Patients were divided in 2 groups according to type of treatment: Group A, high IMA ligation (N=65), Group B, low ligation with lymphadenectomy of IMA root (N=55).
    Results: Preoperatively 59 patients had stage I, 42 patients had stage II  and 19 patients had stage III tumor. A mean of 20.3 +/- 4.5 lymph nodes were removed in group A patients and 18.9 +/- 9.1 in group B patients, and this difference was not statistically significant. Operative time, intraoperative and postoperative complication rates were not different between the two group.
    Conclusions: Low IMA ligation combined with lymph-node dissection at its origin is safe and effective, not time consuming and not associated to increased risk of complications and nerve damage. This technique can be considered as alternative to standard high IMA ligation in selected patients.
    MeSH term(s) Aged ; Dissection ; Female ; Humans ; Laparoscopy/methods ; Ligation ; Lymph Node Excision/methods ; Lymph Nodes/pathology ; Male ; Mesenteric Artery, Inferior ; Middle Aged ; Operative Time ; Postoperative Complications/epidemiology ; Rectal Neoplasms/surgery ; Rectum/surgery ; Retrospective Studies ; Sigmoid Neoplasms/surgery
    Language English
    Publishing date 2019-04-17
    Publishing country Italy
    Document type Journal Article
    ZDB-ID 123320-8
    ISSN 1972-6007 ; 0009-9074
    ISSN (online) 1972-6007
    ISSN 0009-9074
    DOI 10.7417/CT.2019.2121
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  9. Article ; Online: Second jejunal loop adenocarcinoma associated with celiac disease: the first case report.

    Ursi, P / Tarallo, M / Crocetti, D / Cavallaro, G / Fiori, E / D'Andrea, V / De Toma, G

    Il Giornale di chirurgia

    2019  Volume 40, Issue 3, Page(s) 225–229

    Abstract: Introduction: Jejunal adenocarcinoma is a very rare disease but the frequency of this rare carcinoma is higher in celiac patients. We report the first case report of a second jejunal loop adenocarcinoma associated with celiac disease.: Presentation of ...

    Abstract Introduction: Jejunal adenocarcinoma is a very rare disease but the frequency of this rare carcinoma is higher in celiac patients. We report the first case report of a second jejunal loop adenocarcinoma associated with celiac disease.
    Presentation of case: A 47-year-old woman, with a history of celiac disease. Computerized tomographic scans of the abdomen and pelvis demonstrated a severe retroperitoneal lymphoadenopathy, para-aortic, inter-aorto-caval, porto-caval, posterior pancreaticoduodenal space, celiac trunk, lesser gastric curvature, lymph node grouping. The patient underwent digiunal resection and regional lymphadenectomy. Diagnosis was poorly differentiated jejunal adenocarcinoma, infiltrating subserosal adipose tissue, metastasing in five out of eight regional lymph nodes. U.I.C.C. 2017 grading = pT3 pN2 G3 R0; Stage IIIB.
    Discussion: The jejunum accounts for 11-25% of small bowel adenocarcinoma, that accounts for less than 5% of gastrointestinal cancer, notwithstanding that 90% of the mucosa surface area of the digestive tract is made by small intestine. To the best of our knowledge, this is the first report on a second loop jejunal adenocarcinoma complicating celiac disease. In our study, the diagnosis of cancer was made by computed tomography (CT) of abdomen and the patient was operated. For the diagnosis of small bowel tumour, CT enteroclysis has a sensitivity of 85-95% and a specificity of 90-96%. Complete resection (RO) of the jejunal adenocarcinoma, with regional lymph nodes resection and jejuno-jejunal anastomosis should be performed.
    Conclusion: After curative surgical resections of small bowel adenocarcinoma, adjuvant chemo-therapy has not shown a clear benefit in retrospective studies. Preoperative Chemo-Radio-therapy and careful Imaging Staging are the first steps to planning surgery.
    MeSH term(s) Adenocarcinoma/complications ; Adenocarcinoma/diagnostic imaging ; Adenocarcinoma/surgery ; Celiac Disease/complications ; Female ; Humans ; Jejunal Neoplasms/complications ; Jejunal Neoplasms/diagnostic imaging ; Jejunal Neoplasms/surgery ; Jejunum/diagnostic imaging ; Jejunum/surgery ; Lymph Node Excision ; Middle Aged ; Rare Diseases/complications ; Rare Diseases/diagnostic imaging ; Rare Diseases/surgery ; Tomography, X-Ray Computed
    Language English
    Publishing date 2019-09-04
    Publishing country Italy
    Document type Case Reports ; Journal Article
    ZDB-ID 605974-0
    ISSN 1971-145X ; 0391-9005
    ISSN (online) 1971-145X
    ISSN 0391-9005
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  10. Article ; Online: Reducing the risk of trocar site hernias.

    Crocetti, D / Sapienza, P / Pedullà, G / De Toma, G

    Annals of the Royal College of Surgeons of England

    2014  Volume 96, Issue 7, Page(s) 558

    MeSH term(s) Fasciotomy ; Hernia, Ventral/etiology ; Hernia, Ventral/prevention & control ; Humans ; Laparoscopes/adverse effects ; Laparoscopy/adverse effects ; Laparoscopy/methods ; Prognosis ; Risk Assessment ; Surgical Instruments/adverse effects ; Treatment Outcome
    Language English
    Publishing date 2014-09-20
    Publishing country England
    Document type Journal Article
    ZDB-ID 80044-2
    ISSN 1478-7083 ; 0035-8843
    ISSN (online) 1478-7083
    ISSN 0035-8843
    DOI 10.1308/rcsann.2014.96.7.558
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