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  1. Article ; Online: Primary Pure Pancreatic -Type Acinar Cell Carcinoma of the Stomach: A Rare Entity with a Difficult Diagnosis and Review of the Literature.

    Paseiro-Crespo, Gloria / García-Nebreda, María / Roldán Cortés, David / De la Peña Navarro, Itziar / Álvaro Cifuentes, Edurne / Marqués Medina, Elia / Abad-Motos, Ane

    International journal of surgical pathology

    2022  Volume 30, Issue 5, Page(s) 528–538

    Abstract: Acinar cell carcinoma is an uncommon tumour, representing only 1% to 2% of all exocrine pancreatic tumours. Pancreatic-type acinar cell carcinoma can occur in other organs, including the stomach, but it is extraordinarily rare. We report a case of a 51- ... ...

    Abstract Acinar cell carcinoma is an uncommon tumour, representing only 1% to 2% of all exocrine pancreatic tumours. Pancreatic-type acinar cell carcinoma can occur in other organs, including the stomach, but it is extraordinarily rare. We report a case of a 51-year-old woman with a pancreatic-type pure acinar carcinoma of the stomach coexisting with a large cell B lymphoma synchronously, and a literature review of gastric carcinomas with pancreatic cell differentiation. At present there is a preoperative underdiagnosis of these tumours that could be minimized by including this entity in the differential diagnosis of gastric cancer and by performing immunohistochemical analysis with neuroendocrine markers and exocrine pancreatic enzymes.
    MeSH term(s) Carcinoma, Acinar Cell/diagnosis ; Carcinoma, Acinar Cell/pathology ; Female ; Humans ; Immunohistochemistry ; Middle Aged ; Pancreatic Neoplasms/diagnosis ; Pancreatic Neoplasms/pathology ; Stomach Neoplasms/diagnosis ; Stomach Neoplasms/pathology ; Pancreatic Neoplasms
    Language English
    Publishing date 2022-01-24
    Publishing country United States
    Document type Case Reports ; Journal Article ; Review
    ZDB-ID 1336393-1
    ISSN 1940-2465 ; 1066-8969
    ISSN (online) 1940-2465
    ISSN 1066-8969
    DOI 10.1177/10668969211065763
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 4500: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  2. Article ; Online: Submucosal Necrotic Nodule of the Colon: An Enigmatic Entity Potentially Related to Anisakis Infection.

    Gonzalez, Raul S / Pastrián, Laura G / Pyatibrat, Sergey / Arias, Hernan Dario Quiceno / Gil, Yolanda Rodriguez / Booth, Adam L / de la Peña Navarro, Itziar / Garmendia-Irizar, Maddi / Lapointe, Jennifer R / Mobarki, Mousa / Nova-Camacho, Luiz Miguel / Parini, Gina / Romio, Estefania / Alayza, Alejandra Rosell / Pritt, Bobbi S / Ruz-Caracuel, Ignacio

    Archives of pathology & laboratory medicine

    2023  Volume 147, Issue 11, Page(s) 1315–1319

    Abstract: Context.—: Discrete submucosal necrotic nodules may rarely manifest as colon polyps.: Objective.—: To characterize the clinical and pathologic features of this lesion, which has been under-studied in the literature.: Design.—: We conducted an ... ...

    Abstract Context.—: Discrete submucosal necrotic nodules may rarely manifest as colon polyps.
    Objective.—: To characterize the clinical and pathologic features of this lesion, which has been under-studied in the literature.
    Design.—: We conducted an international search to compile a series. For each potential case, photomicrographs were centrally reviewed to confirm the diagnosis. We gathered clinical and pathologic information on each confirmed case.
    Results.—: The final cohort included 25 patients, with 23 having 1 lesion and 2 having several (31 lesions total). Mean patient age was 62 years; 13 patients (52%) were male. Symptoms were nonspecific, although 4 patients (16%) had blood in stool; 14 patients were asymptomatic. Patient history and medications appeared noncontributory. Most cases were located in the right colon (n = 18; 58%). Mean lesion size was 0.4 cm (range, 0.1-1.7 cm). Histology typically showed a centrally necrotic nodule with peripheral fibrosis, chronic inflammation, and sometimes palisading granulomatous inflammation. Percent necrosis ranged from 5% to 95% (average, 70%), and percent fibrosis ranged from 3% to 70% (average, 25%). In 3 cases, degenerated parasitic structures consistent with Anisakis could be seen on hematoxylin-eosin and trichrome special stain. No patient experienced disease recurrence.
    Conclusions.—: Submucosal necrotic nodules can present as colon polyps. Most cases are unifocal, and patients do well on follow-up. At least some examples appear to be caused by Anisakis, implicating patient diet. Patients are often asymptomatic, and many cases show no histologic evidence of the causative agent.
    Language English
    Publishing date 2023-01-03
    Publishing country United States
    Document type Journal Article
    ZDB-ID 194119-7
    ISSN 1543-2165 ; 0363-0153 ; 0096-8528 ; 0003-9985
    ISSN (online) 1543-2165
    ISSN 0363-0153 ; 0096-8528 ; 0003-9985
    DOI 10.5858/arpa.2022-0267-OA
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Ud II Zs.36: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

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