LIVIVO - The Search Portal for Life Sciences

zur deutschen Oberfläche wechseln
Advanced search

Search results

Result 1 - 10 of total 122

Search options

  1. Book ; Online ; Thesis: Elektrophysiologische Charakterisierung neuronaler spannungsabhängiger Calciumströme des Locus coeruleus in zwei experimentellen Parkinson-Modellen der Maus

    Griesbach, Markus [Verfasser] / Decher, Niels [Akademischer Betreuer]

    2023  

    Author's details Markus Griesbach ; Betreuer: Niels Decher
    Keywords Medizin, Gesundheit ; Medicine, Health
    Subject code sg610
    Language German
    Publisher Philipps-Universität Marburg
    Publishing place Marburg
    Document type Book ; Online ; Thesis
    Database Digital theses on the web

    Full text online

    More links

    Kategorien

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  2. Book ; Online ; Thesis: Elektrophysiologische Charakterisierung der Locus coeruleus Neuronen von Parkin­-Knockout Mäusen mit Hilfe der Patch­-Clamp­-Technik

    Müller, Ann-Katrin [Verfasser] / Decher, Niels [Akademischer Betreuer]

    2022  

    Author's details Ann-Katrin Müller ; Betreuer: Niels Decher
    Keywords Medizin, Gesundheit ; Medicine, Health
    Subject code sg610
    Language German
    Publisher Philipps-Universität Marburg
    Publishing place Marburg
    Document type Book ; Online ; Thesis
    Database Digital theses on the web

    Full text online

    More links

    Kategorien

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  3. Article ; Online: Characterization of Kv1.2-mediated outward current in TRIP8b-deficient mice.

    Labbaf, Afsaneh / Dellin, Maurice / Komadowski, Marlene / Chetkovich, Dane M / Decher, Niels / Pape, Hans-Chrisitian / Seebohm, Guiscard / Budde, Thomas / Zobeiri, Mehrnoush

    Biological chemistry

    2023  Volume 404, Issue 4, Page(s) 291–302

    Abstract: Tonic current through hyperpolarization-activated cyclic nucleotide-gated cation (HCN) channels is influencing neuronal firing properties and channel function is strongly influenced by the brain-specific auxiliary subunit tetratricopeptide repeat- ... ...

    Abstract Tonic current through hyperpolarization-activated cyclic nucleotide-gated cation (HCN) channels is influencing neuronal firing properties and channel function is strongly influenced by the brain-specific auxiliary subunit tetratricopeptide repeat-containing Rab8b-interacting protein (TRIP8b). Since Kv1.2 channels and TRIP8b were also suggested to interact, we assessed brain Kv1.2 mRNA and protein expression as well as the reduction of K
    MeSH term(s) Mice ; Animals ; Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels/metabolism ; Neurons/metabolism ; Hippocampus/metabolism ; Brain/metabolism ; Oocytes
    Chemical Substances Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels
    Language English
    Publishing date 2023-03-01
    Publishing country Germany
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 1334659-3
    ISSN 1437-4315 ; 1431-6730 ; 1432-0355
    ISSN (online) 1437-4315
    ISSN 1431-6730 ; 1432-0355
    DOI 10.1515/hsz-2023-0116
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Uc I Zs.50: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  4. Article ; Online: Novel SK channel positive modulators prevent ferroptosis and excitotoxicity in neuronal cells.

    Zhang, Yuequ / Shaabani, Shabnam / Vowinkel, Kirsty / Trombetta-Lima, Marina / Sabogal-Guáqueta, Angélica María / Chen, Tingting / Hoekstra, Jan / Lembeck, Jan / Schmidt, Martina / Decher, Niels / Dömling, Alexander / Dolga, Amalia M

    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

    2024  Volume 171, Page(s) 116163

    Abstract: Small conductance calcium-activated potassium (SK) channel activity has been proposed to play a role in the pathology of several neurological diseases. Besides regulating plasma membrane excitability, SK channel activation provides neuroprotection ... ...

    Abstract Small conductance calcium-activated potassium (SK) channel activity has been proposed to play a role in the pathology of several neurological diseases. Besides regulating plasma membrane excitability, SK channel activation provides neuroprotection against ferroptotic cell death by reducing mitochondrial Ca
    MeSH term(s) Mice ; Animals ; Small-Conductance Calcium-Activated Potassium Channels ; Reactive Oxygen Species/metabolism ; Ferroptosis ; Neurons/metabolism ; Mitochondria/metabolism
    Chemical Substances Small-Conductance Calcium-Activated Potassium Channels ; Reactive Oxygen Species
    Language English
    Publishing date 2024-01-18
    Publishing country France
    Document type Journal Article
    ZDB-ID 392415-4
    ISSN 1950-6007 ; 0753-3322 ; 0300-0893
    ISSN (online) 1950-6007
    ISSN 0753-3322 ; 0300-0893
    DOI 10.1016/j.biopha.2024.116163
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Ud II Zs.198: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  5. Book ; Online ; Thesis: Aufklärung des molekularen krankheitsauslösenden Mechanismus der progressiven kardialen Reizleitungsstörung durch die Mutation G88R im Tandem-Poren-Kanal TASK-4

    Leonhardt, Julia [Verfasser] / Decher, Niels [Akademischer Betreuer]

    2021  

    Author's details Julia Leonhardt ; Betreuer: Niels Decher
    Keywords Medizin, Gesundheit ; Medicine, Health
    Subject code sg610
    Language German
    Publisher Philipps-Universität Marburg
    Publishing place Marburg
    Document type Book ; Online ; Thesis
    Database Digital theses on the web

    Full text online

    More links

    Kategorien

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  6. Article ; Online: Molecular Pharmacology of K

    Decher, Niels / Rinné, Susanne / Bedoya, Mauricio / Gonzalez, Wendy / Kiper, Aytug K

    Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology

    2021  Volume 55, Issue S3, Page(s) 87–107

    Abstract: Potassium channels of the tandem of two-pore-domain ( ... ...

    Abstract Potassium channels of the tandem of two-pore-domain (K
    MeSH term(s) Action Potentials/drug effects ; Action Potentials/physiology ; Binding Sites ; Cardiac Conduction System Disease/drug therapy ; Cardiac Conduction System Disease/genetics ; Cardiac Conduction System Disease/metabolism ; Cardiac Conduction System Disease/pathology ; Gene Expression ; Humans ; Ion Channel Gating/drug effects ; Ion Transport ; Ligands ; Membrane Transport Modulators/chemistry ; Membrane Transport Modulators/classification ; Membrane Transport Modulators/pharmacology ; Migraine Disorders/drug therapy ; Migraine Disorders/genetics ; Migraine Disorders/metabolism ; Migraine Disorders/pathology ; Molecular Dynamics Simulation ; Organ Specificity ; Potassium/metabolism ; Potassium Channels, Tandem Pore Domain/classification ; Potassium Channels, Tandem Pore Domain/genetics ; Potassium Channels, Tandem Pore Domain/metabolism ; Protein Binding ; Protein Isoforms/classification ; Protein Isoforms/genetics ; Protein Isoforms/metabolism ; Protein Structure, Secondary
    Chemical Substances Ligands ; Membrane Transport Modulators ; Potassium Channels, Tandem Pore Domain ; Protein Isoforms ; Potassium (RWP5GA015D)
    Language English
    Publishing date 2021-03-03
    Publishing country Germany
    Document type Journal Article ; Review
    ZDB-ID 1067572-3
    ISSN 1421-9778 ; 1015-8987
    ISSN (online) 1421-9778
    ISSN 1015-8987
    DOI 10.33594/000000339
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 3160: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  7. Article: Common Structural Pattern for Flecainide Binding in Atrial-Selective K

    Mazola, Yuliet / Márquez Montesinos, José C E / Ramírez, David / Zúñiga, Leandro / Decher, Niels / Ravens, Ursula / Yarov-Yarovoy, Vladimir / González, Wendy

    Pharmaceutics

    2022  Volume 14, Issue 7

    Abstract: Atrial fibrillation (AF) is the most common cardiac arrhythmia. Its treatment includes antiarrhythmic drugs (AADs) to modulate the function of cardiac ion channels. However, AADs have been limited by proarrhythmic effects, non-cardiovascular toxicities ... ...

    Abstract Atrial fibrillation (AF) is the most common cardiac arrhythmia. Its treatment includes antiarrhythmic drugs (AADs) to modulate the function of cardiac ion channels. However, AADs have been limited by proarrhythmic effects, non-cardiovascular toxicities as well as often modest antiarrhythmic efficacy. Theoretical models showed that a combined blockade of Na
    Language English
    Publishing date 2022-06-27
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2527217-2
    ISSN 1999-4923
    ISSN 1999-4923
    DOI 10.3390/pharmaceutics14071356
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  8. Article ; Online: Popeye domain containing proteins modulate the voltage-gated cardiac sodium channel Nav1.5.

    Rinné, Susanne / Kiper, Aytug K / Jacob, Ralf / Ortiz-Bonnin, Beatriz / Schindler, Roland F R / Fischer, Sabine / Komadowski, Marlene / De Martino, Emilia / Schäfer, Martin K-H / Cornelius, Tamina / Fabritz, Larissa / Helker, Christian S M / Brand, Thomas / Decher, Niels

    iScience

    2024  Volume 27, Issue 5, Page(s) 109696

    Abstract: Popeye domain containing (POPDC) proteins are predominantly expressed in the heart and skeletal muscle, modulating the ... ...

    Abstract Popeye domain containing (POPDC) proteins are predominantly expressed in the heart and skeletal muscle, modulating the K
    Language English
    Publishing date 2024-04-09
    Publishing country United States
    Document type Journal Article
    ISSN 2589-0042
    ISSN (online) 2589-0042
    DOI 10.1016/j.isci.2024.109696
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  9. Book ; Online ; Thesis: Prämotorisches Modell der Parkinson-Krankheit: Elektrophysiologische Charakterisierung von Locus coeruleus Neuronen nach α-Synuklein-Überexpression im Mausmodell

    Paiba, Annette [Verfasser] / Decher, Niels [Akademischer Betreuer]

    2020  

    Author's details Annette Paiba ; Betreuer: Niels Decher
    Keywords Medizin, Gesundheit ; Medicine, Health
    Subject code sg610
    Language German
    Publisher Philipps-Universität Marburg
    Publishing place Marburg
    Document type Book ; Online ; Thesis
    Database Digital theses on the web

    Full text online

    More links

    Kategorien

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  10. Article ; Online: Cloxyquin activates hTRESK by allosteric modulation of the selectivity filter.

    Schreiber, Julian Alexander / Derksen, Anastasia / Goerges, Gunnar / Schütte, Sven / Sörgel, Jasmin / Kiper, Aytug K / Strutz-Seebohm, Nathalie / Ruck, Tobias / Meuth, Sven G / Decher, Niels / Seebohm, Guiscard

    Communications biology

    2023  Volume 6, Issue 1, Page(s) 745

    Abstract: The TWIK-related spinal cord ... ...

    Abstract The TWIK-related spinal cord K
    MeSH term(s) Potassium Channels/chemistry ; Binding Sites ; Chloroquinolinols/chemistry ; Chloroquinolinols/pharmacology ; Membrane Potentials
    Chemical Substances Potassium Channels ; cloxyquin (BPF36H1G6S) ; Chloroquinolinols
    Language English
    Publishing date 2023-07-18
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ISSN 2399-3642
    ISSN (online) 2399-3642
    DOI 10.1038/s42003-023-05114-4
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

To top