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  1. Article: Correction: Shoaib et al. Neuroprotective Effects of Dried Tubers of

    Shoaib, Ambreen / Siddiqui, Hefazat Hussain / Dixit, Rakesh Kumar / Siddiqui, Sahabjada / Deen, Badrud / Khan, Andleeb / Alrokayan, Salman H / Khan, Haseeb A / Ahmad, Parvaiz

    Plants (Basel, Switzerland)

    2021  Volume 11, Issue 1

    Abstract: We are sorry to report that some images in Figure 1 reported in our recently published paper [ ... ]. ...

    Abstract We are sorry to report that some images in Figure 1 reported in our recently published paper [...].
    Language English
    Publishing date 2021-12-28
    Publishing country Switzerland
    Document type Published Erratum
    ZDB-ID 2704341-1
    ISSN 2223-7747
    ISSN 2223-7747
    DOI 10.3390/plants11010080
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Neuroprotective Effects of Dried Tubers of

    Shoaib, Ambreen / Siddiqui, Hefazat Hussain / Dixit, Rakesh Kumar / Siddiqui, Sahabjada / Deen, Badrud / Khan, Andleeb / Alrokayan, Salman H / Khan, Haseeb A / Ahmad, Parvaiz

    Plants (Basel, Switzerland)

    2020  Volume 9, Issue 3

    Abstract: The present study was designed to explore the neuroprotective properties ... ...

    Abstract The present study was designed to explore the neuroprotective properties of
    Language English
    Publishing date 2020-03-11
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2704341-1
    ISSN 2223-7747
    ISSN 2223-7747
    DOI 10.3390/plants9030356
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Neuroprotective Effects of Dried Tubers of <i>Aconitum napellus</i>

    Shoaib, Ambreen / Siddiqui, Hefazat Hussain / Dixit, Rakesh Kumar / Siddiqui, Sahabjada / Deen, Badrud / Khan, Andleeb / Alrokayan, Salman H / Khan, Haseeb A / Ahmad, Parvaiz

    Plants. 2020 Mar. 11, v. 9, no. 3

    2020  

    Abstract: The present study was designed to explore the neuroprotective properties of ... Aconitum napellus ... (Ranunculaceae). The plant detoxification was done using either water, or cow or goat milk as per the Ayurvedic shodhana method. The evaluation of the ... ...

    Abstract The present study was designed to explore the neuroprotective properties of Aconitum napellus (Ranunculaceae). The plant detoxification was done using either water, or cow or goat milk as per the Ayurvedic shodhana method. The evaluation of the neuroprotective role of A. napellus was performed on diabetic neuropathy induced by streptozotocin in Sprague Dawley (SD) rats. Body mass, blood sugar level, oral glucose tolerance test, hyperalgesia, cold allodynia, motor co-ordination test, and locomotor activity, oxidative biomarkers (TBARS, reduced glutathione, catalase and superoxide dismutase) and sciatic nerve histomorphology were assessed. The in vitro studies were done on human neuroblastoma cell line SHSY-5Y and used an MTT assay to assess the antiproliferative activity of different extracts. Results suggest that the goat milk treated chloroform extract has less percentage of aconitine. After administration of the detoxified chloroform extract to the diabetic animals, there was a significant improvement in the myelination and degenerative changes of the nerve fibers along with behavioral changes (p < 0.05 as compared with diabetic control group). The findings of the in vitro research show an effective neuroprotective role of A. napellus. This suggests that A. napellus should be further investigated for its effect in diabetic pathology.
    Keywords Aconitum napellus ; aconitine ; behavior change ; biomarkers ; blood glucose ; catalase ; chloroform ; cows ; diabetic neuropathy ; glucose tolerance tests ; glutathione ; goat milk ; human cell lines ; laboratory animals ; locomotion ; myelination ; nerve fibers ; nerve tissue ; neuroprotective effect ; rats ; somatosensory disorders ; streptozotocin ; superoxide dismutase ; thiobarbituric acid-reactive substances ; toxicity testing ; tubers
    Language English
    Dates of publication 2020-0311
    Publishing place Multidisciplinary Digital Publishing Institute
    Document type Article
    ZDB-ID 2704341-1
    ISSN 2223-7747
    ISSN 2223-7747
    DOI 10.3390/plants9030356
    Database NAL-Catalogue (AGRICOLA)

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