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  1. Article ; Online: High-Intensity Interval Training and Cardiometabolic Health in the General Population: A Systematic Review and Meta-Analysis of Randomised Controlled Trials.

    Edwards, Jamie J / Griffiths, Megan / Deenmamode, Algis H P / O'Driscoll, Jamie M

    Sports medicine (Auckland, N.Z.)

    2023  Volume 53, Issue 9, Page(s) 1753–1763

    Abstract: Background: High-intensity interval training (HIIT) remains a promising exercise mode in managing cardiometabolic health. Large-scale analyses are necessary to understand its magnitude of effect on important cardiometabolic risk factors and inform ... ...

    Abstract Background: High-intensity interval training (HIIT) remains a promising exercise mode in managing cardiometabolic health. Large-scale analyses are necessary to understand its magnitude of effect on important cardiometabolic risk factors and inform guideline recommendations.
    Objective: We aimed to perform a novel large-scale meta-analysis on the effects of HIIT on cardiometabolic health in the general population.
    Methods: PubMed (MEDLINE), the Cochrane library and Web of Science were systematically searched. Randomised controlled trials (RCTs) published between 1990 and March 2023 were eligible. Research trials reporting the effects of a HIIT intervention on at least one cardiometabolic health parameter with a non-intervention control group were considered.
    Results: This meta-analysis included 97 RCTs with a pooled sample size of 3399 participants. HIIT produced significant improvements in 14 clinically relevant cardiometabolic health parameters, including peak aerobic capacity (VO
    Conclusion: These results provide further support for HIIT in the clinical management of important cardiometabolic health risk factors, which may have implications for physical activity guideline recommendations.
    MeSH term(s) Humans ; High-Intensity Interval Training/methods ; Exercise ; Body Mass Index ; Blood Pressure ; Cardiovascular Diseases/prevention & control ; Randomized Controlled Trials as Topic
    Language English
    Publishing date 2023-05-19
    Publishing country New Zealand
    Document type Meta-Analysis ; Systematic Review
    ZDB-ID 605911-9
    ISSN 1179-2035 ; 0112-1642
    ISSN (online) 1179-2035
    ISSN 0112-1642
    DOI 10.1007/s40279-023-01863-8
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Infographic. Exercise training and resting blood pressure: a large-scale pairwise and network meta-analysis of randomised controlled trials.

    Edwards, Jamie J / Deenmamode, Algis H P / Griffiths, Megan / Arnold, Oliver / Cooper, Nicola J / Wiles, Jonathan D / O'Driscoll, Jamie M

    British journal of sports medicine

    2023  Volume 57, Issue 20, Page(s) 1335–1336

    Language English
    Publishing date 2023-08-18
    Publishing country England
    Document type Journal Article
    ZDB-ID 600592-5
    ISSN 1473-0480 ; 0306-3674
    ISSN (online) 1473-0480
    ISSN 0306-3674
    DOI 10.1136/bjsports-2023-107513
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Exercise training and resting blood pressure: a large-scale pairwise and network meta-analysis of randomised controlled trials.

    Edwards, Jamie J / Deenmamode, Algis H P / Griffiths, Megan / Arnold, Oliver / Cooper, Nicola J / Wiles, Jonathan D / O'Driscoll, Jamie M

    British journal of sports medicine

    2023  Volume 57, Issue 20, Page(s) 1317–1326

    Abstract: Objective: To perform a large-scale pairwise and network meta-analysis on the effects of all relevant exercise training modes on resting blood pressure to establish optimal antihypertensive exercise prescription practices.: Design: Systematic review ... ...

    Abstract Objective: To perform a large-scale pairwise and network meta-analysis on the effects of all relevant exercise training modes on resting blood pressure to establish optimal antihypertensive exercise prescription practices.
    Design: Systematic review and network meta-analysis.
    Data sources: PubMed (Medline), the Cochrane library and Web of Science were systematically searched.
    Eligibility criteria: Randomised controlled trials published between 1990 and February 2023. All relevant work reporting reductions in systolic blood pressure (SBP) and/or diastolic blood pressure (DBP) following an exercise intervention of ≥2 weeks, with an eligible non-intervention control group, were included.
    Results: 270 randomised controlled trials were ultimately included in the final analysis, with a pooled sample size of 15 827 participants. Pairwise analyses demonstrated significant reductions in resting SBP and DBP following aerobic exercise training (-4.49/-2.53 mm Hg, p<0.001), dynamic resistance training (-4.55/-3.04 mm Hg, p<0.001), combined training (-6.04/-2.54 mm Hg, p<0.001), high-intensity interval training (-4.08/-2.50 mm Hg, p<0.001) and isometric exercise training (-8.24/-4.00 mm Hg, p<0.001). As shown in the network meta-analysis, the rank order of effectiveness based on the surface under the cumulative ranking curve (SUCRA) values for SBP were isometric exercise training (SUCRA: 98.3%), combined training (75.7%), dynamic resistance training (46.1%), aerobic exercise training (40.5%) and high-intensity interval training (39.4%). Secondary network meta-analyses revealed isometric wall squat and running as the most effective submodes for reducing SBP (90.4%) and DBP (91.3%), respectively.
    Conclusion: Various exercise training modes improve resting blood pressure, particularly isometric exercise. The results of this analysis should inform future exercise guideline recommendations for the prevention and treatment of arterial hypertension.
    MeSH term(s) Humans ; Antihypertensive Agents ; Blood Pressure/physiology ; Exercise/physiology ; Hypertension/prevention & control ; Network Meta-Analysis ; Randomized Controlled Trials as Topic
    Chemical Substances Antihypertensive Agents
    Language English
    Publishing date 2023-07-25
    Publishing country England
    Document type Systematic Review ; Meta-Analysis ; Journal Article ; Review
    ZDB-ID 600592-5
    ISSN 1473-0480 ; 0306-3674
    ISSN (online) 1473-0480
    ISSN 0306-3674
    DOI 10.1136/bjsports-2022-106503
    Database MEDical Literature Analysis and Retrieval System OnLINE

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