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Article ; Online: Clinical and dermoscopic profile of female pattern hair loss

Deepa John / Seena Palakkal / Mary Vineetha

Asian Journal of Medical Sciences, Vol 15, Iss 1, Pp 79-

2024 Volume 83

Abstract: Background: Female pattern hair loss (FPHL) is one of the hair loss disorders in women characterized by a gradual reduction in hair from the frontal, central, and parietal areas of the scalp. FPHL is more common than previously thought, and data ... ...

Abstract	Background: Female pattern hair loss (FPHL) is one of the hair loss disorders in women characterized by a gradual reduction in hair from the frontal, central, and parietal areas of the scalp. FPHL is more common than previously thought, and data regarding the same are lacking in the Indian literature. Unlike male pattern hair loss, there are not much studies regarding FPHL in South India. Hence, we intend to study the clinical features, associations, and dermoscopic findings of FPHL in our population. Aims and Objectives: The study was conducted to estimate the clinical and dermoscopic features of FPHL. The secondary objective of the study was to estimate the severity of FPHL based on clinical and dermoscopic features. Materials and Methods: The cross-sectional descriptive study was conducted in 300 patients who were clinically diagnosed with FPHL attending the Department of Dermatology, Government Medical College, Kottayam, during a period of 18 months from February 2021 to August 2022. Results: The mean age of patients with FPHL was 46.99±13.8 years. The majority of the patients were asymptomatic. Hair diameter diversity of >20% and miniaturized hair were the most common dermoscopic findings seen in all patients. Honeycombing and yew dots in dermoscopy were seen in 17 and 8.4% of patients, respectively. Conclusion: Dermoscopes are a useful tool to differentiate FPHL from other causes of diffuse hair loss that could mimic FPHL. The presence of yellow dots and honeycombs indicated advanced FPHL. Thus, dermoscopy helps in detecting early FPHL and initiating early treatment of this condition.
Keywords	female pattern hair loss ; dermoscopy ; hair diameter diversity ; Medicine ; R
Subject code	610
Language	English
Publishing date	2024-01-01T00:00:00Z
Publisher	Manipal College of Medical Sciences, Pokhara
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: A Study on Range of Near Visual Acuity in Children with Pseudophakia

Melinda P Letitia / Deepa John / Sarojini Ramani / Malavika Babu / Thomas Kuriakose

Journal of Clinical and Diagnostic Research, Vol 14, Iss 2, Pp NC01-NC

2020 Volume 03

Abstract: Introduction: Accommodation is the ability to see over a range of distances by changing the power of the natural lens. With cataract surgery, this ability is partially or completely abolished. Apparent accommodation or pseudo-accommodation is the ... ...

Abstract	Introduction: Accommodation is the ability to see over a range of distances by changing the power of the natural lens. With cataract surgery, this ability is partially or completely abolished. Apparent accommodation or pseudo-accommodation is the potential of pseudophakic eyes to sustain a good amount of near vision. Aim: To measure near vision in children with pseudophakia unaided, with distance vision correction alone (mono focal lens) in-situ and to measure the minimum near add (bifocal near segment power) required to read 1M (normal reading print size) at 30 cm and 40 cm. Materials and Methods: A cross-sectional study was conducted among children between 5-15 years of age with pseudophakia. Vision assessment was done using Lea symbol chart, at 3 metres for distance and at 30 cm and 40 cm for near. Near vision assessment was done unaided and with distant vision correction alone in place. Minimum spherical power needed to read 1M and child’s class textbooks were also assessed. Results: Sixty-four children were included in the study. Mean age was 10.5 (±3.12) years. Refractive status showed spherical power ranging from -7.00 DS to +1.00 DS (-0.8 Mean, (±1.33 SD), astigmatism ranging from -4.50 DC to +3.00 DC (-1.29 mean, ±1.37 SD). Unaided near vision assessment showed that 41 (64%) could read <2M at 30 cm. Nine children could read 1M at 30 cm and three children could read 1M at 40 cm with distant vision correction alone in place. Conclusion: Sixteen (25%) children in our study were independent of spectacles for reading 1M at a reading distance of 30 cm. Nine children (14.1%) read 1M at 30 cm with monofocal spectacles. Twenty-three children (35.9%) had good functional near vision and did not require any add for near work. Forty-six children (71.8%) required only 2 D or less near add for their classwork at 30 cm. Thus, monofocal or reduced near add can give these children a better quality of vision.
Keywords	paediatric pseudophakia ; pseudoaccommodation ; retained accommodation ; Medicine ; R
Subject code	360
Language	English
Publishing date	2020-02-01T00:00:00Z
Publisher	JCDR Research and Publications Private Limited
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Concurrent Infections of Conidiobolus Coronatus with Disseminated Tuberculosis Presenting as Bilateral Orbital Cellulitis

Deepa John / Aparna Irodi / Joy Sarojini Michael

Journal of Clinical and Diagnostic Research, Vol 10, Iss 4, Pp ND01-ND

2016 Volume 02

Abstract: Zygomycetes species contains two orders of organisms that infect humans, namely Mucorales and Entomophthorales. Entomophthorales cause chronic infection in immunocompetent patients, invading subcutaneous tissues but are non-angioinvasive. This includes ... ...

Abstract	Zygomycetes species contains two orders of organisms that infect humans, namely Mucorales and Entomophthorales. Entomophthorales cause chronic infection in immunocompetent patients, invading subcutaneous tissues but are non-angioinvasive. This includes Basidiobolus ranarum, Conidiobolus incongruus and Conidiobolus coronatus. We report a case of disseminated tuberculosis with Conidiobolus coronatus infection presenting as orbital cellulitis in an adolescent.
Keywords	basal meningitis ; bilateral proptosis ; maxillary sinusitis ; rhinofacial mycosis ; Medicine ; R
Language	English
Publishing date	2016-04-01T00:00:00Z
Publisher	JCDR Research and Publications Private Limited
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Disseminated rhinosporidiosis with conjunctival involvement in an immunocompromised patient

Deepa John / Satheesh S. T. Selvin / Aparna Irodi / Pushpa Jacob

Middle East African Journal of Ophthalmology, Vol 24, Iss 1, Pp 51-

2017 Volume 53

Abstract: Rhinosporidiosis is a granulomatous infection of mucocutaneous tissue caused by Rhinosporidium seeberi that most commonly occurs in the nasal cavity. Ocular rhinosporidiosis affects primarily the conjunctiva. Diagnosis of rhinosporidiosis is based on ... ...

Abstract	Rhinosporidiosis is a granulomatous infection of mucocutaneous tissue caused by Rhinosporidium seeberi that most commonly occurs in the nasal cavity. Ocular rhinosporidiosis affects primarily the conjunctiva. Diagnosis of rhinosporidiosis is based on strong clinical suspicion and is confirmed by histopathological examination. We report a rare case of conjunctival rhinosporidiosis in an immunocompromised patient (human immunodeficiency virus) with disseminated cutaneous rhinosporidiosis. A 44-year-old male presented with a swelling in the right upper eyelid for 6 months. Excision biopsy of the ocular lesion showed multiple thick-walled, variable-sized sporangia containing endospores within the subepithelium suggestive of rhinosporidiosis. A multidrug regimen of systemic cycloserine, ketoconazole, and dapsone was administered to treat disseminated rhinosporidiosis, in addition to antiretroviral therapy. There was good response with reduction in the swellings.
Keywords	Conjunctival rhinosporidiosis ; disseminated rhinisporidiosis ; immunocompromised ; Rhinosporidium seeberi ; Ophthalmology ; RE1-994 ; Medicine ; R
Language	English
Publishing date	2017-01-01T00:00:00Z
Publisher	Medknow Publications
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Profile and Causes of Low Vision and Blindness in Children from Two Schools for the Blind in Tamil Nadu, Southern India

Deepa John / Padma Paul / Lekha Abraham / Malavika Babu / Visalakshi Peravali / Thomas Kuriakose

Journal of Clinical and Diagnostic Research, Vol 12, Iss 9, Pp NC05-NC

2018 Volume 07

Abstract: Introduction: World Health Organisation’s (WHO) “Vision 2020” right to sight programme gives high priority towards control of ChildHood Blindness (CHB). Blind school screening provides data on the causes of CHB to focus on health care programmes towards ... ...

Abstract	Introduction: World Health Organisation’s (WHO) “Vision 2020” right to sight programme gives high priority towards control of ChildHood Blindness (CHB). Blind school screening provides data on the causes of CHB to focus on health care programmes towards prevention of CHB. Aim: To determine the causes of CHB seen in local schools for the blind, to compare these with reports from India and focus on changes in the causes of CHB over the years. Materials and Methods: A cross-sectional study was conducted in two schools for the blind in Tamil Nadu, India. Children less than 18 years were included. Best Corrected Visual Acuity (BCVA), anterior segment and dilated fundus examination was done for all children. Information was gathered as per WHO prevention of blindness (WHO/PBL) form. Results: BCVA in the better eye was 6/24 to 3/60 in 31 children (16.8%), <3/60 to no perception of light in 154 children (83.2%). The causes of blindness based on anatomical site were retina 77(41.5%), whole globe 59(32%), cornea 14(7.5%), optic nerve 14(7.5%), lens 10(5.7%), refractive error in 7(3.8%) and uvea in 4(2%). Hence, 14(7.5%) of the causes were preventable and 21(11.4%) were treatable; thus 35(18.9%) were avoidable causes of blindness. Conclusion: Retinal dystrophies were the major cause of CHB in our study. Posterior segment anomalies contributed to 50% of the causes for CHB. Our study showed that one-fifth of children had avoidable blindness. Regular screening in well baby clinics, schools and in the community is needed for early identification of avoidable blindness in children.
Keywords	avoidable blindness ; childhood blindness ; visual impairment ; Medicine ; R
Subject code	796
Language	English
Publishing date	2018-09-01T00:00:00Z
Publisher	JCDR Research and Publications Private Limited
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Granulocytic Sarcoma in an Adult with Relapsed Acute Myeloid Leukaemia

Neethu Ann Kurien / Deepa John / Geeta Chacko / Pushpa Jacob

Journal of Clinical and Diagnostic Research, Vol 10, Iss 1, Pp ND03-ND

2016 Volume 04

Abstract: Granulocytic sarcoma is an extramedullary tumour consisting of malignant granulocytic precursor cells that is common among children with acute myeloid leukaemia (AML). We report a case of orbital granulocytic sarcoma in an adult with relapsed ... ...

Abstract	Granulocytic sarcoma is an extramedullary tumour consisting of malignant granulocytic precursor cells that is common among children with acute myeloid leukaemia (AML). We report a case of orbital granulocytic sarcoma in an adult with relapsed undifferentiated AML–M0. It presented as bilateral medial canthal swellings. An incisional biopsy confirmed the diagnosis of granulocytic sarcoma. The swelling resolved with re-induction chemotherapy.
Keywords	aml-m0 subtype ; extramedullary tumour ; myeloid sarcoma ; orbital mass ; Medicine ; R
Language	English
Publishing date	2016-01-01T00:00:00Z
Publisher	JCDR Research and Publications Private Limited
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Study of Barrier to Help Seeking and its Relationships with Disability in Patients with Headache

Deepa John / Dushad Ram / Harsha Sundarmurthy / Harshal Rathod / Snehal Rathod

Journal of Clinical and Diagnostic Research, Vol 10, Iss 10, Pp VC01-VC

2016 Volume 05

Abstract: Introduction: Headache is among the first three most prevalent disorders with a wide treatment gap due to barriers in help seeking. Headache has been associated with disability. However, the relationship of barriers to help-seeking and disability are ... ...

Abstract	Introduction: Headache is among the first three most prevalent disorders with a wide treatment gap due to barriers in help seeking. Headache has been associated with disability. However, the relationship of barriers to help-seeking and disability are unexplored. Aim: To find out the barriers to help seeking and its relationship with headache related disability in patients with headache. Materials and Methods: In this hospital based cross-sectional study, 200 consecutive subjects with headache attending a tertiary care centre were recruited as per selection criteria and assessed with Sociodemographic & Clinical Proforma, Mini International Neuropsychiatric Interview (MINI), Barriers to Help Seeking Scale (BHSS), The Henry Ford Hospital Headache Disability Inventory (HDI). Results: High mean score was observed on BHSS subscale need for control and self reliance (19.45; SD ±9.66) and minimizing problem and resignation (10.02; SD ±6.98). Mean score on the HDI was 25.65 (SD ± 14.09). Socioeconomic status of the patient was statistically significant and positively associated with need for control and self reliance (p=0.035), concrete barriers and distrust of care givers (p=0.039), emotional control (p=0.005), and privacy (p=0.002). Occupational status had significant association with need for control and self-reliance (p=0.01), minimizing problem and resignation (p=0.033), and emotional control (p=0.006). Score on hospital headache disability inventory significantly predicted the value of score on concrete barriers and distrust of caregivers domain of HDI (p=0.001). Conclusion: Autonomy and under estimation of seriousness of headache are common barriers to help seeking. Pattern of help seeking barriers may vary with socio-economic status and occupational status, while disability varies with gender and severity of headache. Headache associated disability is positively associated with concrete barriers.
Keywords	functional impairment ; illness behaviour ; treatment barriers ; Medicine ; R
Subject code	360
Language	English
Publishing date	2016-10-01T00:00:00Z
Publisher	JCDR Research and Publications Private Limited
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Headache Disability, Suicidality and Pain Catastrophization - Are They Related

Harshal Rathod / Dushad Ram / Harsha Sundarmurthy / Snehal Rathod / Deepa John

Journal of Clinical and Diagnostic Research, Vol 10, Iss 11, Pp VC01-VC

2016 Volume 04

Abstract: Introduction: Studies have found that headache is associated with suicidality. Some demographic and clinical features have been reported to be associated with suicidality. Pain catastrophizing and disability may also have bearing on suicidality in ... ...

Abstract	Introduction: Studies have found that headache is associated with suicidality. Some demographic and clinical features have been reported to be associated with suicidality. Pain catastrophizing and disability may also have bearing on suicidality in patients with headache. Aim: To evaluate the relationship between pain disability and catastrophizing in headache and suicidal behaviour. Materials and Methods: Patients diagnosed with headache were recruited from neurology Out-Patient Department (OPD). With ethical approval and informed consent, patients were subjected to a structured interview. Headache disability and pain catastrophizing was assessed with the Henry Ford Hospital Headache Disability Inventory (HDI) and Pain Catastrophy Scale (PCS) respectively. For evaluation of suicidal ideation and behaviour, MINI International Neuropsychiatric Interview (MINI Plus) scale and The Columbia-Suicide Severity Rating Scale (C-SSRS) were applied. Data was analysed with Mann-Whitney U test and Kruskal-Wallis test using appropriate statistical programs. Results: In 200 patients of headache, male: female ratio was 0.48: 1. Headache disability was significantly higher in females (p=0.060) and unemployed (p=0.019) patients whereas, pain catastrophizing was significant in patients belonging to low socioeconomic class (p=0.045). Headache disability and pain catastrophizing had significant association with suicidal ideation. Disability score was significantly associated with the score of deterrents (p=0.067) and controllability (p=0.039) subscale of intensity of suicidal ideation. There were four patients who actually attempted suicide. Pain catastrophizing was significantly associated with non-suicidal self injurious behaviour (p=0.041). Conclusion: Disability due to headache and pain catastrophizing is associated with increased suicidal tendencies, behaviour and suicidal attempts. Headache in females and patients in rural habitat, unemployed individuals belonging to low socioeconomic class need special attention to reduce high ...
Keywords	functional impairment ; pain sensitivity ; suicidal behaviour ; Medicine ; R
Subject code	616
Language	English
Publishing date	2016-11-01T00:00:00Z
Publisher	JCDR Research and Publications Private Limited
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Asymptomatic Intracorneal Graphite Deposits following Graphite Pencil Injury

Sheeja Susan John / Deepa John / Swetha Sara Philip

Case Reports in Ophthalmological Medicine, Vol

2012 Volume 2012

Keywords	Ophthalmology ; RE1-994 ; Medicine ; R ; DOAJ:Ophthalmology ; DOAJ:Medicine (General) ; DOAJ:Health Sciences
Language	English
Publishing date	2012-01-01T00:00:00Z
Publisher	Hindawi Publishing Corporation
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Ocular Features and Visual Outcome in Children with Moyamoya Disease and Moyamoya Syndrome

Deepa John / Karthik Muthusamy / Bhavagna Bandla / Sniya Valsa Sudhakar / Maya Thomas

Journal of Clinical and Diagnostic Research, Vol 10, Iss 5, Pp NR01-NR

A Case Series

2016 Volume 04

Abstract: Moya Moya Disease (MMD) is characterised by idiopathic vasculopathy affecting the terminal internal carotid arteries resulting in the formation of extensive collaterals at the base of the brain, leptomeninges and parenchymal regions with resultant ... ...

Abstract	Moya Moya Disease (MMD) is characterised by idiopathic vasculopathy affecting the terminal internal carotid arteries resulting in the formation of extensive collaterals at the base of the brain, leptomeninges and parenchymal regions with resultant infarcts and bleeds. Four children presented with clinico-radiological features suggestive of Moyamoya disease/syndrome. This includes global developmental delay, recurrent seizures, transient ischaemic attacks and impaired vision. The first patient had vision of 6/15 in both eyes with bilateral optic disc pallor. Second case also had bilateral optic disc pallor with arteriolar attenuation, but had vision of perception of light only in both eyes. The third child had vision of 6/60 with alternate divergent squint and clinical features suggestive of Neurofibromatosis 1 (NF 1). Fourth patient presented with poor fixation in both eyes with bilateral total cataract. He underwent bilateral cataract surgery with intraocular lens implantation and vision improved to 2/60 with good fixation. We also describe their medical and neurosurgical interventions in this report.
Keywords	developmental cataract ; functional vision ; seizures in children ; Medicine ; R
Subject code	610
Language	English
Publishing date	2016-05-01T00:00:00Z
Publisher	JCDR Research and Publications Private Limited
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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