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Article ; Online: Structural basis of NINJ1-mediated plasma membrane rupture in cell death.

Degen, Morris / Santos, José Carlos / Pluhackova, Kristyna / Cebrero, Gonzalo / Ramos, Saray / Jankevicius, Gytis / Hartenian, Ella / Guillerm, Undina / Mari, Stefania A / Kohl, Bastian / Müller, Daniel J / Schanda, Paul / Maier, Timm / Perez, Camilo / Sieben, Christian / Broz, Petr / Hiller, Sebastian

Nature

2023  Volume 618, Issue 7967, Page(s) 1065–1071

Abstract: Eukaryotic cells can undergo different forms of programmed cell death, many of which culminate in plasma membrane rupture as the defining terminal ... ...

Abstract Eukaryotic cells can undergo different forms of programmed cell death, many of which culminate in plasma membrane rupture as the defining terminal event
MeSH term(s) Animals ; Humans ; Mice ; Cell Adhesion Molecules, Neuronal/chemistry ; Cell Adhesion Molecules, Neuronal/genetics ; Cell Adhesion Molecules, Neuronal/metabolism ; Cell Adhesion Molecules, Neuronal/ultrastructure ; Cell Membrane/metabolism ; Cell Membrane/pathology ; Cell Membrane/ultrastructure ; Cryoelectron Microscopy ; Nerve Growth Factors/chemistry ; Nerve Growth Factors/genetics ; Nerve Growth Factors/metabolism ; Nerve Growth Factors/ultrastructure ; Mutagenesis, Site-Directed ; Biopolymers/chemistry ; Biopolymers/genetics ; Biopolymers/metabolism ; Cell Death
Chemical Substances Cell Adhesion Molecules, Neuronal ; Nerve Growth Factors ; NINJ1 protein, human ; Ninj1 protein, mouse ; Biopolymers
Language English
Publishing date 2023-05-17
Publishing country England
Document type Journal Article
ZDB-ID 120714-3
ISSN 1476-4687 ; 0028-0836
ISSN (online) 1476-4687
ISSN 0028-0836
DOI 10.1038/s41586-023-05991-z
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