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  1. Article ; Online: Aortic valve cusp prolapse before and after valve-sparing aortic root replacement.

    Deja, Marek A

    Heart (British Cardiac Society)

    2022  Volume 109, Issue 1, Page(s) 8–9

    MeSH term(s) Humans ; Aortic Valve/diagnostic imaging ; Aortic Valve/surgery ; Aortic Valve Insufficiency/diagnostic imaging ; Aortic Valve Insufficiency/etiology ; Aortic Valve Insufficiency/surgery ; Aorta ; Prolapse ; Treatment Outcome ; Reoperation
    Language English
    Publishing date 2022-12-13
    Publishing country England
    Document type Editorial ; Comment
    ZDB-ID 1303417-0
    ISSN 1468-201X ; 1355-6037
    ISSN (online) 1468-201X
    ISSN 1355-6037
    DOI 10.1136/heartjnl-2022-321390
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  2. Article ; Online: Commentary: Achieving "symmetrical" annular geometry during bicuspid aortic valve repair.

    Rankin, J Scott / Deja, Marek A

    The Journal of thoracic and cardiovascular surgery

    2022  

    Language English
    Publishing date 2022-12-20
    Publishing country United States
    Document type Editorial
    ZDB-ID 3104-5
    ISSN 1097-685X ; 0022-5223
    ISSN (online) 1097-685X
    ISSN 0022-5223
    DOI 10.1016/j.jtcvs.2022.12.011
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  3. Article ; Online: Commentary: Hurry up while you are operating…or, better, plan carefully before you start.

    Deja, Marek A

    The Journal of thoracic and cardiovascular surgery

    2019  Volume 159, Issue 1, Page(s) 179

    Language English
    Publishing date 2019-02-27
    Publishing country United States
    Document type Editorial
    ZDB-ID 3104-5
    ISSN 1097-685X ; 0022-5223
    ISSN (online) 1097-685X
    ISSN 0022-5223
    DOI 10.1016/j.jtcvs.2019.02.051
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  4. Article ; Online: Invited Commentary.

    Deja, Marek A

    The Annals of thoracic surgery

    2017  Volume 104, Issue 1, Page(s) 77–78

    Language English
    Publishing date 2017
    Publishing country Netherlands
    Document type Journal Article ; Comment
    ZDB-ID 211007-6
    ISSN 1552-6259 ; 0003-4975
    ISSN (online) 1552-6259
    ISSN 0003-4975
    DOI 10.1016/j.athoracsur.2016.11.030
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  5. Article ; Online: It is better to be readmitted than dead.

    Deja, Marek A

    The Journal of thoracic and cardiovascular surgery

    2017  Volume 154, Issue 2, Page(s) 453–454

    MeSH term(s) Aortic Valve Stenosis ; Heart Valve Prosthesis ; Humans ; Patient Readmission ; Retrospective Studies ; Transcatheter Aortic Valve Replacement
    Language English
    Publishing date 2017-04-28
    Publishing country United States
    Document type Editorial ; Comment
    ZDB-ID 3104-5
    ISSN 1097-685X ; 0022-5223
    ISSN (online) 1097-685X
    ISSN 0022-5223
    DOI 10.1016/j.jtcvs.2017.04.059
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  6. Article: Stem cells mobilization by cardiopulmonary bypass after coronary artery bypass grafting.

    Kowalówka, Adam R / Wojakowski, Wojciech / Bachowski, Ryszard / Deja, Marek A

    Postepy w kardiologii interwencyjnej = Advances in interventional cardiology

    2022  Volume 18, Issue 4, Page(s) 450–458

    Abstract: Introduction: Expression of haematopoietic stem and progenitor cells occurs as a result of an inflammatory reaction caused by a damaged organ. Patients undergoing coronary artery bypass surgery (CABG) using cardiopulmonary bypass (CPB) are exposed to an ...

    Abstract Introduction: Expression of haematopoietic stem and progenitor cells occurs as a result of an inflammatory reaction caused by a damaged organ. Patients undergoing coronary artery bypass surgery (CABG) using cardiopulmonary bypass (CPB) are exposed to an inflammatory reaction, which may be a trigger in the mobilization of regenerative cells.
    Aim: To assess the impact of CPB on stem and progenitor cells mobilization in patients scheduled for CABG.
    Material and methods: Twenty patients with stable coronary disease, who were scheduled for CABG, were included in the study. Peripheral blood samples were collected perioperatively: 2 h before surgery, before CPB, at CPB weaning, 24 h postoperatively, and on the 6
    Results: The following cell populations were identified during cardiac surgery: haematopoietic stem cells (HSC), mesenchymal cells (MSC), endothelial progenitors (EPC), and very small embryonic-like cells (VSEL). The profile of cell mobilization coincides with the perioperative inflammatory response. Mobilization of stem and progenitor cells induced by CPB did not occur in any of the isolated cell lines (
    Conclusions: Mobilization of haematopoietic stem and progenitor cells was not related with CPB. The inflammatory reaction was associated with perioperative trauma. Cell release was inhibited in patients with diabetes.
    Language English
    Publishing date 2022-12-17
    Publishing country Poland
    Document type Journal Article
    ISSN 1734-9338
    ISSN 1734-9338
    DOI 10.5114/aic.2022.122874
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  7. Article ; Online: Results of aortic valve replacement for aortic stenosis and moderate functional mitral regurgitation.

    Kowalówka, Adam R / Wańha, Wojciech / Malinowski, Marcin / Kania-Olejnik, Paulina / Deja, Marek A

    Kardiologia polska

    2023  

    Abstract: Background: Referral and admission echocardiography (ECHO) in patients scheduled for aortic valve replacement (AVR) with aortic stenosis (AS) may differ in the assessment of moderate functional mitral regurgitation (FMR).: Aims: Our study was to ... ...

    Abstract Background: Referral and admission echocardiography (ECHO) in patients scheduled for aortic valve replacement (AVR) with aortic stenosis (AS) may differ in the assessment of moderate functional mitral regurgitation (FMR).
    Aims: Our study was to determine the truly moderate-FMR and evaluate its impact on survival.
    Methods: We conducted an observational study of patients referred for AVR with AS and up to moderate FMR, between 2014 and 2019. Patients were divided into three groups: (1) no/mild (N-FMR); (2) moderate-FMR on one ECHO (either at referral or admission) termed incidental (I-FMR); (3) moderate FMR in two studies (both at referral and admission) termed permanent (PM-FMR).
    Results: The referral and admission assessment were performed median 35 days apart. Of the 679 elective patients who underwent elective isolated AVR, 516 patients had N-FMR, 102 patients had I-FMR, and 61 patients had PM-FMR. Median follow-up was 46 months (22.5-58.5); max 73.3. 30-day mortality was 2.5% vs. 1% vs. 8.2% (N-FMR vs. I-FMR vs. PM-FMR, respectively; P = 0.01). Five-year survival was 84.1% in N-FMR vs. 88.5% in I-FMR vs. 60.6% in PM-FMR group, where was the lowest (P <0.001). In multivariable modeling PM-FMR increased mortality (hazard ratio [HR], 1.88 [1.05-3.37]; P = 0.03). The I-FMR had no effect on mortality (HR, 0.67 [0.32-1.37]; P = 0.28). Five-year survival after excluding 30-day mortality was 86.3% vs. 89.4% vs. 66.0%; (N-FMR vs. I-FMR vs. PM-FMR, respectively; P = 0.02). The PM-FMR increased late mortality (HR, 2.17 [1.14-4.15]; P = 0.01).
    Conclusions: In patients undergoing isolated AVR for AS, the presence of permanent moderate FMR significantly impacts 30-day and mid-term survival.
    Language English
    Publishing date 2023-04-25
    Publishing country Poland
    Document type Journal Article
    ZDB-ID 411492-9
    ISSN 1897-4279 ; 0022-9032
    ISSN (online) 1897-4279
    ISSN 0022-9032
    DOI 10.33963/KP.a2023.0090
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  8. Article ; Online: Exercise echocardiography after tricuspid annuloplasty.

    Piekarska, Magda / Haberka, Maciej / Bałys, Mariusz / Malinowski, Marcin / Deja, Marek A

    Kardiologia polska

    2022  Volume 80, Issue 5, Page(s) 601–603

    Language English
    Publishing date 2022-02-23
    Publishing country Poland
    Document type Journal Article
    ZDB-ID 411492-9
    ISSN 1897-4279 ; 0022-9032
    ISSN (online) 1897-4279
    ISSN 0022-9032
    DOI 10.33963/KP.a2022.0059
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  9. Article: Assessment of adrenal reserve and secretion of cortisol in patients over 60 years of age undergoing cardiac surgery.

    Piekarska, Magda L / Buda, Marta / Deja, Marek A

    Kardiochirurgia i torakochirurgia polska = Polish journal of cardio-thoracic surgery

    2019  Volume 16, Issue 3, Page(s) 118–123

    Abstract: Introduction: Cortisol level affects the prognosis of patients after cardiac surgery. Meanwhile, there are no clear guidelines for steroid supplementation after a cardiac operation. The relationship between age and blood cortisol levels has not been ... ...

    Abstract Introduction: Cortisol level affects the prognosis of patients after cardiac surgery. Meanwhile, there are no clear guidelines for steroid supplementation after a cardiac operation. The relationship between age and blood cortisol levels has not been finally clarified.
    Aim: Assessment of adrenal reserve and secretion of cortisol in patients over 60 years of age undergoing cardiac surgery.
    Material and methods: The study included 20 patients of both sexes referred for cardiac surgery. A short ACTH synthetic stimulation test was carried out. Assessment of cortisol secretion was carried out in the morning on the day of surgery and the 1
    Results: A result within the normal range for the adrenal reserve was found in 19 of the 20 patients enrolled in the study. The short Synacthen test predicted postoperative secretion of cortisol (
    Conclusions: A short Synacthen test allows one to predict secretion of cortisol after cardiac surgery. Greater secretion of cortisol after cardiac surgery may be associated with a more difficult postoperative course. There was no decrease in cortisol secretion with age.
    Language English
    Publishing date 2019-10-28
    Publishing country Poland
    Document type Journal Article
    ZDB-ID 2237053-5
    ISSN 1897-4252 ; 1731-5530
    ISSN (online) 1897-4252
    ISSN 1731-5530
    DOI 10.5114/kitp.2019.88600
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  10. Article ; Online: Del Nido cardioplegia as a safe and effective method of myocardial protection in adult patients undergoing cardiac surgery: a single‑center experience.

    Kuciński, Jakub / Górska, Aleksandra / Deja, Marek A

    Kardiologia polska

    2019  Volume 77, Issue 11, Page(s) 1040–1046

    Abstract: Background: Del Nido (DN) cardioplegia is increasingly popular in adult cardiac surgery. It allegedly allows for up to 90 minutes of safe myocardial ischemia with a single dose.: Aims: We aimed to evaluate the benefits of DN cardioplegia.: Methods!# ...

    Abstract Background: Del Nido (DN) cardioplegia is increasingly popular in adult cardiac surgery. It allegedly allows for up to 90 minutes of safe myocardial ischemia with a single dose.
    Aims: We aimed to evaluate the benefits of DN cardioplegia.
    Methods: Of the 2108 patients undergoing coronary or heart valve surgery with the use of cardiopulmonary bypass (CPB) between January 1, 2016, and September 30, 2017, 1236 (59%) received DN and 872 (41%) received cold blood cardioplegia. We retrospectively analyzed the collected data of all consecutive on‑pump patients to assess early mortality and postoperative troponin T release. A multivariable analysis of both outcomes adjusted for propensity to receive DN cardioplegia was performed.
    Results: Patients protected with DN cardioplegia had longer CPB and aortic cross‑clamp times (P <0.001) but received fewer doses of cardioplegia. Median postoperative troponin T levels were higher in the DN‑cardioplegia than CB‑cardioplegia group: 0.324 ng/ml (interquartile range [IQR], 0.210-0.559 ng/ml) vs 0.285 ng/ml (IQR, 0.191-0.496 ng/ml); P = 0.01. However, when adjusted for the cross‑clamp time, propensity to receive DN cardioplegia, and other factors, DN cardioplegia was associated with lower postoperative troponin T levels. Early mortality rates did not differ between DN and CB cardioplegia (3.6% vs 3%; P = 0.54).
    Conclusions: Del Nido cardioplegia is a safe and effective method of myocardial protection in adults. It allows for a longer redosing interval with a safety profile and mortality comparable to those for CB cardioplegia, as shown by lower troponin T release when corrected for the time of myocardial ischemia.
    MeSH term(s) Aged ; Cardiac Surgical Procedures ; Cardiopulmonary Bypass ; Female ; Heart Arrest, Induced/methods ; Heart Valves/surgery ; Humans ; Male ; Middle Aged ; Poland ; Postoperative Period ; Retrospective Studies ; Treatment Outcome ; Troponin T/blood
    Chemical Substances Troponin T
    Language English
    Publishing date 2019-09-05
    Publishing country Poland
    Document type Comparative Study ; Journal Article
    ZDB-ID 411492-9
    ISSN 1897-4279 ; 0022-9032
    ISSN (online) 1897-4279
    ISSN 0022-9032
    DOI 10.33963/KP.14964
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