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Audio / Video ; Online: Impactos do COVID-19

Delgado, Fernanda

efeitos da pandemia nos setores de Energia Elétrica e Petróleo e Gás

2020

Abstract: A crise nos setores de energia elétrica e petróleo e gás se destaca no cenário econômico afetado pela pandemia do Covid-19. Segundo a pesquisadora Fernanda Delgado, da FGV Energia, há mais de 18 anos o preço do barril de petróleo não alcança um patamar ... ...

Abstract	A crise nos setores de energia elétrica e petróleo e gás se destaca no cenário econômico afetado pela pandemia do Covid-19. Segundo a pesquisadora Fernanda Delgado, da FGV Energia, há mais de 18 anos o preço do barril de petróleo não alcança um patamar tão baixo: U$S 20 dólares. Essa grande queda foi ocasionada pela superoferta de produção na Arábia Saudita e na Rússia.
Schlagwörter	COVID-19 ; Pandemia ; Crise econômica ; Petróleo & Gás ; Energia elétrica ; Economia ; Saúde ; Coronavírus ; Petróleo e gás - Brasil ; Energia elétrica - Brasil ; Crise econômica - Brasil ; covid19
Sprache	Portugiesisch
Erscheinungsdatum	2020-04-01
Erscheinungsland	br
Dokumenttyp	Audio / Video ; Online
Datenquelle	BASE - Bielefeld Academic Search Engine (Lebenswissenschaftliche Auswahl)

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Artikel: Targeting Class I-II-III PI3Ks in Cancer Therapy: Recent Advances in Tumor Biology and Preclinical Research.

Thibault, Benoît / Ramos-Delgado, Fernanda / Guillermet-Guibert, Julie

Cancers

2023 Band 15, Heft 3

Abstract: Phosphatidylinositol-3-kinase (PI3K) enzymes, producing signaling phosphoinositides at plasma and intracellular membranes, are key in intracellular signaling and vesicular trafficking pathways. PI3K is a family of eight enzymes divided into three classes ...

Abstract	Phosphatidylinositol-3-kinase (PI3K) enzymes, producing signaling phosphoinositides at plasma and intracellular membranes, are key in intracellular signaling and vesicular trafficking pathways. PI3K is a family of eight enzymes divided into three classes with various functions in physiology and largely deregulated in cancer. Here, we will review the recent evidence obtained during the last 5 years on the roles of PI3K class I, II and III isoforms in tumor biology and on the anti-tumoral action of PI3K inhibitors in preclinical cancer models. The dependency of tumors to PI3K isoforms is dictated by both genetics and context (e.g., the microenvironment). The understanding of class II/III isoforms in cancer development and progression remains scarce. Nonetheless, the limited available data are consistent and reveal that there is an interdependency between the pathways controlled by all PI3K class members in their role to promote cancer cell proliferation, survival, growth, migration and metabolism. It is unknown whether this feature contributes to partial treatment failure with isoform-selective PI3K inhibitors. Hence, a better understanding of class II/III functions to efficiently inhibit their positive and negative interactions with class I PI3Ks is needed. This research will provide the proof-of-concept to develop combination treatment strategies targeting several PI3K isoforms simultaneously.
Sprache	Englisch
Erscheinungsdatum	2023-01-27
Erscheinungsland	Switzerland
Dokumenttyp	Journal Article ; Review
ZDB-ID	2527080-1
ISSN	2072-6694
ISSN	2072-6694
DOI	10.3390/cancers15030784
Datenquelle	MEDical Literature Analysis and Retrieval System OnLINE

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Artikel ; Online: Rockrose Land Management: Contribution of Periodic Harvesting to Increase Value and to Control Cistus ladanifer L. Shrublands

Frazão, David Franco / Gonçalves, José Carlos / Silva, Amélia M. / Delgado, Fernanda

Forests. 2023 Mar. 21, v. 14, no. 3

2023

Abstract: Cistus ladanifer L. (Cistaceae) occupies extensive areas as a dominant species (shrublands) or is associated to other major forest typologies in the Iberian Peninsula. Cistus ladanifer shrublands are mostly present in oligotrophic lands with little ... ...

Abstract	Cistus ladanifer L. (Cistaceae) occupies extensive areas as a dominant species (shrublands) or is associated to other major forest typologies in the Iberian Peninsula. Cistus ladanifer shrublands are mostly present in oligotrophic lands with little valorisation and management and as they develop over the years (up to 20-years-old) they promote the ignition and perpetuation of fire. To contribute to the proper management and valorisation of such systems, a 5-year-old dense shrubland was evaluated for its labdanum resin, seeds, and biomass productivity using different non-destructive harvest periodicities (annual and biennial) and seasons (early, mid-, and late summer), in a two-year case-study. Annual harvest modality maximized labdanum resin productivity (reaching 230 ± 50 kg∙ha⁻¹∙2 years⁻¹ at late summer) and photosynthetic biomass productivity. In contrast, a biennial harvest yielded significant amounts of more diversified products. It maximized seeds productivity (reaching 75 ± 41 kg∙ha⁻¹∙2 years⁻¹ independently of the summer season) and lignified biomass. However, it also reached a labdanum resin productivity of 134 ± 20 kg∙ha⁻¹∙2 yearrs⁻¹ at late summer and a photosynthetic biomass productivity around two times lower than the annual harvest. In this study, we propose two modalities of periodic harvest to be considered as proper long cycle management practices of rockrose lands. It intends to minimize fire risks, break the vegetation auto-succession mechanism, and increase profit from non-productive lands based on three direct outputs with a myriad of applications and valorisation pathways.
Schlagwörter	Cistus ladanifer ; biomass production ; dominant species ; forests ; land management ; photosynthesis ; shrublands ; summer ; Iberian Peninsula
Sprache	Englisch
Erscheinungsverlauf	2023-0321
Erscheinungsort	Multidisciplinary Digital Publishing Institute
Dokumenttyp	Artikel ; Online
ZDB-ID	2527081-3
ISSN	1999-4907
ISSN	1999-4907
DOI	10.3390/f14030638
Datenquelle	NAL Katalog (AGRICOLA)

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Artikel: Mediterranean Lavenders from Section

Domingues, Joana / Delgado, Fernanda / Gonçalves, José Carlos / Zuzarte, Mónica / Duarte, Ana Paula

Metabolites

2023 Band 13, Heft 3

Abstract: Globally, climate change and wildfires are disrupting natural ecosystems, thus setting several endemic species at risk. The ... ...

Abstract	Globally, climate change and wildfires are disrupting natural ecosystems, thus setting several endemic species at risk. The genus
Sprache	Englisch
Erscheinungsdatum	2023-02-24
Erscheinungsland	Switzerland
Dokumenttyp	Journal Article ; Review
ZDB-ID	2662251-8
ISSN	2218-1989
ISSN	2218-1989
DOI	10.3390/metabo13030337
Datenquelle	MEDical Literature Analysis and Retrieval System OnLINE

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Artikel: Multitemporal Land Use and Cover Analysis Coupled with Climatic Change Scenarios to Protect the Endangered Taxon

Almeida, Alice Maria / Delgado, Fernanda / Roque, Natália / Ribeiro, Maria Margarida / Fernandez, Paulo

Plants (Basel, Switzerland)

2023 Band 12, Heft 16

Abstract: Climate change and land use and land cover (LULC) change are impacting the species' geographic distribution, causing range shifts and reducing suitable habitats. ...

Abstract	Climate change and land use and land cover (LULC) change are impacting the species' geographic distribution, causing range shifts and reducing suitable habitats.
Sprache	Englisch
Erscheinungsdatum	2023-08-10
Erscheinungsland	Switzerland
Dokumenttyp	Journal Article
ZDB-ID	2704341-1
ISSN	2223-7747
ISSN	2223-7747
DOI	10.3390/plants12162914
Datenquelle	MEDical Literature Analysis and Retrieval System OnLINE

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Artikel: Chemical profile and eco-safety evaluation of essential oils and hydrolates from Cistus ladanifer, Helichrysum italicum, Ocimum basilicum and Thymbra capitata

Ferraz, Celso Afonso / Sousa, Ana Catarina A. / Caramelo, Débora / Delgado, Fernanda / de Oliveira, Ana Palmeira / Pastorinho, M. Ramiro

Industrial crops and products. 2022 Jan., v. 175

2022

Abstract: The demand for natural-based products for industrial applications is increasing sharply and therefore the search for new alternatives to the plants traditionally used is growing. These alternative plants can be an important source of bioactive compounds ... ...

Abstract	The demand for natural-based products for industrial applications is increasing sharply and therefore the search for new alternatives to the plants traditionally used is growing. These alternative plants can be an important source of bioactive compounds under a circular economy approach. Considering the potential future use of new plant products by the industry, it is necessary to assess the risk associated with their introduction into the ecosystem. This work aims to provide an insight into the volatile profiles and evaluate the potential (eco)toxic effects of essential oils (EO’s) and hydrolates of four plant species, namely rockrose (Cistus ladanifer), curry plant (Helichrysum italicum), conehead thyme (Thymbra capitata) and basil (Ocimum basilicum). Chemical analysis were performed by GC-MS and acute toxicity tests were performed using the model organism Daphnia magna. The essential oil and the hydrolate from H. italicum, as well as all the other hydrolates caused no immobilization up to the highest concentrations tested, suggesting that all hydrolates present low to no risk towards D. magna. Similarly, the essential oil of H. italicum, presented negligible risk towards D. magna. For C. ladanifer and T. capitata essential oils, the EC₅₀ (the concentration estimated to immobilize 50 per cent of the Daphnia) at 48 h varied between 199.7 mg/L and 12.1 mg/L, respectively. The essential oil from C. ladanifer was mainly characterised by monoterpene hydrocarbons, while the H. italicum was richer in sesquiterpene hydrocarbons. Both essential oil and hydrolate from T. capitata contained exclusively monoterpene hydrocarbons with a particularly high content of carvacrol. The higher acute toxicity of T. capitata essential oil can be attributed to the high amount of carvacrol present in the distillate. Overall, of the essential oils and hydrolates tested, all can be classified as practically non-toxic, except for T. capitata essential oil that, according to the Globally Harmonized System of Classification and Labelling of Chemicals (GHS) of the United Nations, can be classified as moderately toxic.
Schlagwörter	Cistus ladanifer ; Daphnia magna ; Helichrysum italicum ; Ocimum basilicum ; Thymbra capitata ; acute toxicity ; basil ; carvacrol ; chemical analysis ; circular economy ; curry ; ecosystems ; essential oils ; hydrosols ; monoterpenoids ; risk ; risk assessment ; sesquiterpenoids ; thyme
Sprache	Englisch
Erscheinungsverlauf	2022-01
Erscheinungsort	Elsevier B.V.
Dokumenttyp	Artikel
ZDB-ID	1132158-1
ISSN	1872-633X ; 0926-6690
ISSN (online)	1872-633X
ISSN	0926-6690
DOI	10.1016/j.indcrop.2021.114232
Datenquelle	NAL Katalog (AGRICOLA)

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Artikel: Cistus ladanifer seeds: From ancient snack to novel and sustainable food ingredient

Frazão, David F. / Paulo, Luísa / Peres, Fátima / Resende, Mafalda / Santo, Christophe Espírito / Barroca, Celina / Moitinho, António / Delgado, Fernanda

Journal of food composition and analysis. 2022 June, v. 109

2022

Abstract: Cistus ladanifer is a persistent, abundant and widespread underexplored resource in the Iberian Peninsula. The seeds have been used as food for centuries, although their nutritional value and potential as food ingredients have not been exploited until ... ...

Abstract	Cistus ladanifer is a persistent, abundant and widespread underexplored resource in the Iberian Peninsula. The seeds have been used as food for centuries, although their nutritional value and potential as food ingredients have not been exploited until now. In this study seeds from natural shrubland were collected three times during summer for two consecutive years. Analytical evaluation of the macronutrient content, fatty acids, and mineral composition was performed. Regarding the macronutrients, seeds showed a carbohydrate content of 46.1 ± 1.6%, a fibre content of 20.9 ± 1.4%, a protein content of 16.2 ± 0.4%, a lipid content of 13.0 ± 1.1%, and an ash content of 3.87 ± 0.16%. The fatty acids were found to be mostly unsaturated (74.05 ± 0.59%). Potassium was the most abundant mineral (975 ± 53 mg/100 g) followed by phosphorous, magnesium and calcium. In conclusion, several nutrient-related label claims may be used for C. ladanifer seeds as food ingredient. Compared to common cereals, nuts and seeds, C. ladanifer seeds are close to flax and chia seeds in relation to nutritional composition, and to pine nuts in relation to mineral composition.
Schlagwörter	Cistus ladanifer ; Salvia hispanica ; ash content ; calcium ; carbohydrate content ; fiber content ; flax ; food composition ; lipid content ; magnesium ; mineral content ; nutrient content ; nutritive value ; phosphorus ; potassium ; protein content ; shrublands ; summer ; Iberian Peninsula
Sprache	Englisch
Erscheinungsverlauf	2022-06
Erscheinungsort	Elsevier Inc.
Dokumenttyp	Artikel
ZDB-ID	743572-1
ISSN	0889-1575 ; 1096-0481
ISSN	0889-1575 ; 1096-0481
DOI	10.1016/j.jfca.2022.104503
Datenquelle	NAL Katalog (AGRICOLA)

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Buch ; Artikel ; Online: The decarbonization of gas in the Southern Cone of South America

Gomes, Ieda / Caratori, Luciano / Carlino, Hernan / Delgado, Fernanda / Sousa, Luara

2021

Abstract: South America is endowed with vast energy resources and natural gas plays an important role in the supply of energy to the region. A few countries in the Southern Cone area such as Argentina, Brazil and Chile, also meet part of their demand needs with ... ...

Abstract	South America is endowed with vast energy resources and natural gas plays an important role in the supply of energy to the region. A few countries in the Southern Cone area such as Argentina, Brazil and Chile, also meet part of their demand needs with imported liquefied natural gas (LNG) and/or pipeline gas. In line with the objectives of diversifying to indigenous sources, reduce GHG emissions and advance the Paris Agenda towards net-zero emissions, there has been a push to increase the use of renewable sources in those countries, mainly solar and wind. In 2019 the installed capacity of wind energy more than doubled in Argentina year-on-year (albeit from a small base) whilst solar grew 19.6 per cent and 23.9 per cent in Brazil and Chile respectively. For many years, South American countries have been looking for viable ways to develop decarbonized gas such as biomethane, biogas and, more recently, hydrogen. This paper analyzes the efforts by Argentina, Brazil and Chile to decarbonize gas to reduce greenhouse gases emissions, including some significant projects already being developed and in operation. The paper also assesses the initiatives, timing and challenges, and describe the bottlenecks - including costs, infrastructure, financing and regulatory issues - impacting on the development of projects and the more widespread use of biogas, biomethane and hydrogen in these economies. Finally, the possibility of creating a regional market for decarbonized gas is investigated. Looking at the region overall, there is significant potential for biogas and biomethane in Argentina and Brazil, but less so in Chile. In order to realise that potential, particularly for biomethane further incentives and regulations will be required. For hydrogen, while PV seems to be the most competitive source for green hydrogen, levelised costs of green hydrogen remain at least double the cost of hydrogen from natural gas without CCUS. Although the three countries are pursuing decarbonised gas projects, initial planning is still in progress and there is a lack of sufficient coordination between government and policy makers to drive the development. Particularly for hydrogen, large scale developments are likely to be beyond the current NDC horizon of 2030, but putting a clear transition pathway in place soon will increase the likelihood of achieving the significant potential for decarbonized gases in the three Southern Cone countries.
Schlagwörter	ddc:330 ; blue' hydrogen ; Argentina ; biogas ; Biomethane ; Brazil ; Chile ; decarbonization ; green hydrogen ; Hydrogen ; Natural gas ; Renewable Energy ; Southern Cone
Thema/Rubrik (Code)	621
Sprache	Englisch
Verlag	Oxford: The Oxford Institute for Energy Studies
Erscheinungsland	de
Dokumenttyp	Buch ; Artikel ; Online
Datenquelle	BASE - Bielefeld Academic Search Engine (Lebenswissenschaftliche Auswahl)

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Artikel ; Online: Medications reverse logistics

Lima, Pedro Augusto Bertucci / Delgado, Fernanda Camila Martinez / dos Santos, Thalita Lacerda / Florentino, Anna Patrícya

Cleaner Logistics and Supply Chain

A systematic literature review and a method for improving the Brazilian case

2022 Band 3

Abstract: Medication waste is a concern for today's society, from both environmental and public health perspectives. This study aims to contribute to the issue by presenting a mixed-methods approach to the problem through reverse logistics. First, a systematic ... ...

Abstract	Medication waste is a concern for today's society, from both environmental and public health perspectives. This study aims to contribute to the issue by presenting a mixed-methods approach to the problem through reverse logistics. First, a systematic literature review was performed to map the literature and identify the best practices implemented worldwide. The review also provided information for the second part of the study: a proposal for the improvement of Brazil's medications reverse logistics system, viewed from an information management perspective. The method proposed introduces a mechanism for estimating the quantity of unused medications that should be returned to the system. Three groups of stakeholders evaluated the proposal by answering a semi-structured questionnaire. The research also adopted Institutional Theory to draw its conclusions. The literature review revealed a concentration of studies in the United States, a country which has a major concern for public health. Brazil was the second most studied country in the literature: the majority of its studies relating to environmental aspects. Both countries, however, particularly recognize the need to improve the ways unused medication is collected from consumers and returned to the reverse logistics system, and see their respective governments as the main actors promoting this process. The measurement system proposed in this study supports the development of better reverse logistics systems for countries that use information systems to manage medication supply chains. Some resistance to the implementation of the improving method was observed in drugstores due to the costs involved; these costs should be shared with other stakeholders in the pharmaceutical sector.
Schlagwörter	Information management ; Institutional Theory ; Medications ; Reverse logistics ; Sustainability
Thema/Rubrik (Code)	306
Sprache	Englisch
Erscheinungsland	nl
Dokumenttyp	Artikel ; Online
ISSN	2772-3909
Datenquelle	BASE - Bielefeld Academic Search Engine (Lebenswissenschaftliche Auswahl)

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Artikel ; Online: Humulus lupulus aqueous extract and hydrolate as a potential ingredient for cosmetics: chemical characterization and in vitro antimicrobial, cytotoxicity, antioxidant and anti-inflammatory assessment.

Valente, João Vasco / Palmeira-de-Oliveira, Rita / Guiomar, Liliana / Vaz, Cátia V / Rolo, Joana / Gaspar, Carlos / Oliveira, Ana Sofia / Caramelo, Débora / Breitenfeld, Luiza / Gonçalves, José Carlos / Delgado, Fernanda / Martinez-de-Oliveira, José / Palmeira-de-Oliveira, Ana

Fitoterapia

2024 Band 175, Seite(n) 105861

Abstract: Humulus lupulus extracts have in their composition different molecules, such as polyphenols, α-acids, β-acids, and hydrocarbons, which contribute to the plant's medicinal properties. These molecules are associated with antimicrobial, antioxidant and anti- ...

Abstract	Humulus lupulus extracts have in their composition different molecules, such as polyphenols, α-acids, β-acids, and hydrocarbons, which contribute to the plant's medicinal properties. These molecules are associated with antimicrobial, antioxidant and anti-inflammatory activities. Objective: This work focuses on the evaluation of H. lupulus biological activities, with the aim of evaluating its potential for inclusion in cosmetic formulations. Methods: Two distinct aqueous extracts and two hydrolates obtained via hydrodistillation were evaluated. These include the flower parts (FE, FH) and the mix of aboveground parts (ME, MH). The chemical profiles for both aqueous extracts and hydrolates were identified by high performance liquid chromatography (HPLC) and gas chromatography-mass spectrometry (GC-MS). Antimicrobial, antioxidant, cytotoxicity, and anti-inflammatory activity were tested in vitro using standard methods. Results: Rutin was the major compound found in FE (40.041 μg mg Conclusion: The studied H. lupulus aqueous extracts and hydrolates revealed that FH stands out as the most promising bioactive source for cosmetic formulations. However, future research addressing antimicrobial activity is necessary to confirm its potential incorporation into dermatological and cosmetic formulations.
Sprache	Englisch
Erscheinungsdatum	2024-02-12
Erscheinungsland	Netherlands
Dokumenttyp	Journal Article
ZDB-ID	412385-2
ISSN	1873-6971 ; 0367-326X
ISSN (online)	1873-6971
ISSN	0367-326X
DOI	10.1016/j.fitote.2024.105861
Datenquelle	MEDical Literature Analysis and Retrieval System OnLINE

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