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  1. Article ; Online: Non-Local Parallel Processing and Database Settlement Using Multiple Teleportation Followed by Grover Post-Selection.

    Delgado, Francisco / Cardoso-Isidoro, Carlos

    Entropy (Basel, Switzerland)

    2023  Volume 25, Issue 2

    Abstract: Quantum information applications emerged decades ago, initially introducing a parallel development that mimicked the approach and development of classical computer science. However, in the current decade, novel computer-science concepts were rapidly ... ...

    Abstract Quantum information applications emerged decades ago, initially introducing a parallel development that mimicked the approach and development of classical computer science. However, in the current decade, novel computer-science concepts were rapidly extended to the fields of quantum processing, computation, and communication. Thus, areas such as artificial intelligence, machine learning, and neural networks have their quantum versions; furthermore, the quantum brain properties of learning, analyzing, and gaining knowledge are discussed. Quantum properties of matter conglomerates have been superficially explored in such terrain; however, the settlement of organized quantum systems able to perform processing can open a new pathway in the aforementioned domains. In fact, quantum processing involves certain requisites as the settlement of copies of input information to perform differentiated processing developed far away or in situ to diversify the information stored there. Both tasks at the end provide a database of outcomes with which to perform either information matching or final global processing with at least a subset of those outcomes. When the number of processing operations and input information copies is large, parallel processing (a natural feature in quantum computation due to the superposition) becomes the most convenient approach to accelerate the database settlement of outcomes, thus affording a time advantage. In the current study, we explored certain quantum features to realize a speed-up model for the entire task of processing based on a common information input to be processed, diversified, and finally summarized to gain knowledge, either in pattern matching or global information availability. By using superposition and non-local properties, the most valuable features of quantum systems, we realized parallel local processing to set a large database of outcomes and subsequently used post-selection to perform an ending global processing or a matching of information incoming from outside. We finally analyzed the details of the entire procedure, including its affordability and performance. The quantum circuit implementation, along with tentative applications, were also discussed. Such a model could be operated between large processing technological systems using communication procedures and also on a moderately controlled quantum matter conglomerate. Certain interesting technical aspects involving the non-local control of processing via entanglement were also analyzed in detail as an associated but notable premise.
    Language English
    Publishing date 2023-02-18
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2014734-X
    ISSN 1099-4300 ; 1099-4300
    ISSN (online) 1099-4300
    ISSN 1099-4300
    DOI 10.3390/e25020376
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Quantum Entanglement and State-Transference in Fenna-Matthews-Olson Complexes: A Post-Experimental Simulation Analysis in the Computational Biology Domain.

    Delgado, Francisco / Enríquez, Marco

    International journal of molecular sciences

    2023  Volume 24, Issue 13

    Abstract: Fenna-Mathews-Olson complexes participate in the photosynthetic process of Sulfur Green Bacteria. These biological subsystems exhibit quantum features which possibly are responsible for their high efficiency; the latter may comprise multipartite ... ...

    Abstract Fenna-Mathews-Olson complexes participate in the photosynthetic process of Sulfur Green Bacteria. These biological subsystems exhibit quantum features which possibly are responsible for their high efficiency; the latter may comprise multipartite entanglement and the apparent tunnelling of the initial quantum state. At first, to study these aspects, a multidisciplinary approach including experimental biology, spectroscopy, physics, and math modelling is required. Then, a global computer modelling analysis is achieved in the computational biology domain. The current work implements the Hierarchical Equations of Motion to numerically solve the open quantum system problem regarding this complex. The time-evolved states obtained with this method are then analysed under several measures of entanglement, some of them already proposed in the literature. However, for the first time, the maximum overlap with respect to the closest separable state is employed. This authentic multipartite entanglement measure provides information on the correlations, not only based on the system bipartitions as in the usual analysis. Our study has led us to note a different view of FMO multipartite entanglement as tiny contributions to the global entanglement suggested by other more basic measurements. Additionally, in another related trend, the initial state, considered as a Förster Resonance Energy Transfer, is tracked using a novel approach, considering how it could be followed under the fidelity measure on all possible permutations of the FMO subsystems through its dynamical evolution by observing the tunnelling in the most probable locations. Both analyses demanded significant computational work, making for a clear example of the complexity required in computational biology.
    MeSH term(s) Bacterial Proteins/chemistry ; Light-Harvesting Protein Complexes/metabolism ; Fluorescence Resonance Energy Transfer ; Computer Simulation ; Chlorobi ; Quantum Theory
    Chemical Substances Bacterial Proteins ; Light-Harvesting Protein Complexes
    Language English
    Publishing date 2023-06-29
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2019364-6
    ISSN 1422-0067 ; 1422-0067 ; 1661-6596
    ISSN (online) 1422-0067
    ISSN 1422-0067 ; 1661-6596
    DOI 10.3390/ijms241310862
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: A Painful Periumbilical Nodule in a Reproductive-aged Woman.

    Immaneni, Supriya / Delgado, Francisco / Baucom, Mark

    Indian journal of dermatology

    2024  Volume 68, Issue 6, Page(s) 729

    Language English
    Publishing date 2024-01-09
    Publishing country India
    Document type Journal Article
    ZDB-ID 416069-1
    ISSN 1998-3611 ; 0019-5154
    ISSN (online) 1998-3611
    ISSN 0019-5154
    DOI 10.4103/ijd.ijd_90_23
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: SU

    Delgado, Francisco

    Entropy (Basel, Switzerland)

    2018  Volume 20, Issue 8

    Abstract: The gate array version of quantum computation uses logical gates adopting convenient forms for computational algorithms based on the algorithms classical computation. Two-level quantum systems are the basic elements connecting the binary nature of ... ...

    Abstract The gate array version of quantum computation uses logical gates adopting convenient forms for computational algorithms based on the algorithms classical computation. Two-level quantum systems are the basic elements connecting the binary nature of classical computation with the settlement of quantum processing. Despite this, their design depends on specific quantum systems and the physical interactions involved, thus complicating the dynamics analysis. Predictable and controllable manipulation should be addressed in order to control the quantum states in terms of the physical control parameters. Resources are restricted to limitations imposed by the physical settlement. This work presents a formalism to decompose the quantum information dynamics in S U ( 2 2 d ) for 2 d -partite two-level systems into 2 2 d - 1 S U ( 2 ) quantum subsystems. It generates an easier and more direct physical implementation of quantum processing developments for qubits. Easy and traditional operations proposed by quantum computation are recovered for larger and more complex systems. Alternating the parameters of local and non-local interactions, the procedure states a universal exchange semantics on the basis of generalized Bell states. Although the main procedure could still be settled on other interaction architectures by the proper selection of the basis as natural grammar, the procedure can be understood as a momentary splitting of the 2 d information channels into 2 2 d - 1 pairs of 2 level quantum information subsystems. Additionally, it is a settlement of the quantum information manipulation that is free of the restrictions imposed by the underlying physical system. Thus, the motivation of decomposition is to set control procedures easily in order to generate large entangled states and to design specialized dedicated quantum gates. They are potential applications that properly bypass the general induced superposition generated by physical dynamics.
    Language English
    Publishing date 2018-08-17
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2014734-X
    ISSN 1099-4300 ; 1099-4300
    ISSN (online) 1099-4300
    ISSN 1099-4300
    DOI 10.3390/e20080610
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: Reuse of the paramedian forehead flap pedicle: A case report.

    Immaneni, Supriya / Harvey, David T / Delgado, Francisco

    SAGE open medical case reports

    2023  Volume 11, Page(s) 2050313X231160913

    Abstract: The paramedian forehead flap is an axial flap which utilizes vascular support from the supratrochlear artery to repair extensive nasal defects. Adverse outcomes including flap necrosis, infection, alar rim pull, and poor cosmesis can be seen with this ... ...

    Abstract The paramedian forehead flap is an axial flap which utilizes vascular support from the supratrochlear artery to repair extensive nasal defects. Adverse outcomes including flap necrosis, infection, alar rim pull, and poor cosmesis can be seen with this flap. We report an 85-year-old woman with chronic obstructive pulmonary disease who underwent a staged paramedian forehead flap repair with a cartilage inlay complicated by moderate left alar rim necrosis and pedicle notching. In this patient, we were able to salvage the original pedicle and reposition it to achieve a satisfactory functional and cosmetic outcome.
    Language English
    Publishing date 2023-03-21
    Publishing country England
    Document type Case Reports
    ZDB-ID 2736953-5
    ISSN 2050-313X
    ISSN 2050-313X
    DOI 10.1177/2050313X231160913
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: Dynamics of Episodic Magma Injection and Migration at Yellowstone Caldera: Revisiting the 2004–2009 Episode of Caldera Uplift With InSAR and GPS Data

    Delgado, Francisco / Grandin, Raphaël

    Journal of geophysical research. 2021 Aug., v. 126, no. 8

    2021  

    Abstract: The 2004–2009 caldera uplift is the largest instrumentally recorded episode of unrest at Yellowstone caldera. We use GPS and Interferometric Synthetic Aperture Radar (InSAR) time series spanning 2004–2015, with a focus in the aforementioned event to ... ...

    Abstract The 2004–2009 caldera uplift is the largest instrumentally recorded episode of unrest at Yellowstone caldera. We use GPS and Interferometric Synthetic Aperture Radar (InSAR) time series spanning 2004–2015, with a focus in the aforementioned event to understand the mechanisms of unrest. InSAR data recorded ∼25 and ∼20 cm of uplift at the Sour Creek (SCD) and Mallard Lake (MLD) resurgent domes during 2004–2009, and ∼8 cm of subsidence at the Norris Geyser Basin (NGB) during 2004–2008. The SCD/MLD uplift was followed by subsidence across the caldera floor with a maximum at MLD of ∼1.5–2.5 cm/yr, and no deformation at NGB. The best‐fit source models for the 2004–2009 period are two horizontal sills at depths of ∼8.7 and 10.6 km for the caldera source and NGB, respectively, with volume changes of 0.354 and −0.121 km³, and an overpressure of ∼0.1 MPa. The InSAR and GPS time series record exponentially increasing followed by exponentially decreasing uplift between 2004 and 2009, which is indicative of magma injection into the caldera reservoir, with no need for other mechanisms of unrest. However, magma extraction from NGB to the caldera is unable to explain the subsidence coeval with the caldera uplift. Models of magma injection can also explain other episodes of caldera uplift like that in 2014–2015. Distributed sill opening models show that magma is stored across the caldera source with no clear boundary between MLD and SCD. Since the magma overpressure is orders of magnitude below the tensile strength of the encasing rock, historical episodes of unrest like these are very unlikely to trigger an eruption.
    Keywords Anas platyrhynchos ; basins ; deformation ; geophysics ; interferometry ; lakes ; research ; streams ; subsidence ; synthetic aperture radar ; tensile strength ; time series analysis
    Language English
    Dates of publication 2021-08
    Publishing place John Wiley & Sons, Ltd
    Document type Article
    Note JOURNAL ARTICLE
    ISSN 2169-9313
    DOI 10.1029/2021JB022341
    Database NAL-Catalogue (AGRICOLA)

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  7. Article ; Online: Optimizing emergency department imaging utilization for pulmonary emboli: A study on the effects of IV contrast rationing.

    Delgado, Francisco / Hajibonabi, Farid / Hislop, Jada / Johnson, Jamlik Omari / Naeem, Muhammad / Hanna, Tarek

    Clinical imaging

    2024  Volume 107, Page(s) 110090

    Abstract: Purpose: To study the impact of a contrast mitigation protocol on imaging utilization for pulmonary embolism (PE) in the emergency department (ED).: Material and methods: Medical records of ED patients with suspected PE who underwent CT pulmonary ... ...

    Abstract Purpose: To study the impact of a contrast mitigation protocol on imaging utilization for pulmonary embolism (PE) in the emergency department (ED).
    Material and methods: Medical records of ED patients with suspected PE who underwent CT pulmonary angiography (CTPA) or ventilation-perfusion (VQ) scans were analyzed in control (3/15/22-4/15/22) and test (5/15/22-6/15/22) periods. The test period included a contrast mitigation protocol due to a global iodinated contrast shortage (05/2022-06/2022). Out of 610 scans, 28 were excluded for non-PE indications. Patient demographics, time metrics, and imaging reports were recorded.
    Results: Among 11,019 ED visits, there were 582 imaging events for suspected PE. The test period exhibited a significantly lower imaging rate of 4.16 % compared to 6.54 % in the control period (p < 0.001). CTPA usage decreased by 47.73 %, while VQ scan usage increased by 775.00 % during the test period. Test period positivity rate was 0.82 %, with CTPA at 0.58 % (1/173) and VQ scan at 1.43 % (1/70). In the control period, the positivity rate was 0.29 %, with CTPA at 0.30 % (1/331) and VQ scan at 0.00 % (0/8). Previous hospitalization history was significantly higher in the test period (70/243 vs. 39/339, p < 0.001). The positivity rates between the two periods showed no significant difference (p = 0.57). There were no significant differences in ED length of stay and image acquisition times.
    Conclusion: The contrast mitigation protocol reduced CTPA use, increased VQ scans, and maintained positivity rates and image acquisition times. However, concerns persist about unnecessary imaging and low positivity rates, necessitating further research to optimize PE diagnostic algorithms.
    MeSH term(s) Humans ; Diagnostic Imaging ; Pulmonary Embolism/diagnostic imaging ; Contrast Media ; Emergency Service, Hospital ; Computed Tomography Angiography/methods
    Chemical Substances Contrast Media
    Language English
    Publishing date 2024-01-20
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1028123-x
    ISSN 1873-4499 ; 0899-7071
    ISSN (online) 1873-4499
    ISSN 0899-7071
    DOI 10.1016/j.clinimag.2024.110090
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Teaching motivators, facilitators, and barriers among dermatology volunteer clinical faculty.

    Delgado, Francisco / Immaneni, Supriya / MacKelfresh, Jamie B / Yeung, Howa

    Archives of dermatological research

    2023  Volume 315, Issue 10, Page(s) 2995–2998

    Abstract: Volunteer clinical faculty in private practice provide important clinical teaching and mentorship to dermatology residency programs. Motivations for serving as volunteer clinical faculty in specialties such as obstetrics and gynecology, emergency ... ...

    Abstract Volunteer clinical faculty in private practice provide important clinical teaching and mentorship to dermatology residency programs. Motivations for serving as volunteer clinical faculty in specialties such as obstetrics and gynecology, emergency medicine, and family medicine have been identified; however, there is limited data on what drives private practice physicians to volunteer to teach in dermatology residency training programs. This study examined motivators, facilitators, and barriers to serving as volunteer clinical faculty using an anonymous survey of dermatologists, Mohs surgeons, and dermatopathologists affiliated with Emory University's dermatology residency program. Among the 38 invited participants, 26 (68%) completed the survey. The types of practices represented include general dermatology (71%), Mohs surgery (23%), cosmetic dermatology (58%), and dermatopathology (27%). Traditional lectures and impromptu teaching sessions were the most utilized teaching modalities, with 14 (54%) and 11 (42%) of respondents reporting usage, respectively. Most respondents ranked altruistic statements such as "opportunity to be helpful to others" (26, 100%), "providing service to the field of dermatology" (25, 96%), and "enjoyment of teaching" (25, 96%) as important motivations. In contrast, extrinsic rewards such as career advancement and increased income were rated as least important. Significant barriers included limited time for travel and teaching and credentialing. Proposed facilitators included promoting schedule flexibility, increasing teaching supplies, and streamlining credentialing. This single-center study may have limited generalizability to other residency programs with varying characteristics. The motivators, facilitators, and barriers identified by this survey can inform dermatology residency programs on how to maximize volunteer clinical faculty recruitment, retention, and engagement, thus strengthening clinical teaching and mentorship offered.
    MeSH term(s) Humans ; Dermatology ; Internship and Residency ; Surveys and Questionnaires ; Volunteers ; Faculty
    Language English
    Publishing date 2023-09-26
    Publishing country Germany
    Document type Letter
    ZDB-ID 130131-7
    ISSN 1432-069X ; 0340-3696
    ISSN (online) 1432-069X
    ISSN 0340-3696
    DOI 10.1007/s00403-023-02727-x
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Perceptions and attitudes regarding HIV pre-exposure prophylaxis (PrEP) among dermatology clinicians and trainees.

    Delgado, Francisco / Hijab, Eman / Siira, Meron / Yeung, Howa

    Archives of dermatological research

    2022  Volume 315, Issue 6, Page(s) 1789–1792

    Abstract: In 2020, over 1.2 million people were at risk of acquiring human immunodeficiency virus (HIV), though only 25% were prescribed pre-exposure prophylaxis (PrEP). Given the multitude of dermatologic manifestations of HIV and other sexually transmitted ... ...

    Abstract In 2020, over 1.2 million people were at risk of acquiring human immunodeficiency virus (HIV), though only 25% were prescribed pre-exposure prophylaxis (PrEP). Given the multitude of dermatologic manifestations of HIV and other sexually transmitted infections, dermatologic care can serve as the entry point to the HIV care continuum. Currently, there is limited data on specialists' perspectives on HIV PrEP prescribing. We aimed to survey clinicians and trainees in an academic dermatology department about HIV PrEP-related knowledge, attitudes, and practices. Survey questions were adapted from existing literature on HIV stigma and PrEP-related knowledge, attitudes, and practices. Composite scores for each domain were averaged and compared between clinicians and trainees using Wilcoxon's signed rank test or Fisher's exact test. Of 135 providers invited, 31 (23%) completed the survey (11 clinicians and 20 trainees). Of the 31 participants, 16 (52%) had specialized HIV experience and training. When asked about discriminatory beliefs, nine participants (29%) agreed that HIV infection is a "consequence of irresponsible behavior." PrEP knowledge was low, with 13 (42%) participants answering zero out of 3 PrEP knowledge questions correctly. Additionally, 10 (91%) clinicians reported poor knowledge of PrEP side effects, and eight clinicians (73%) indicated they were "not comfortable at all" in prescribing PrEP. No participant had prescribed PrEP, and 22 (70%) participants had never discussed PrEP with patients. Dermatology clinicians and trainees reported some levels of HIV stigma. Substantial gaps in PrEP knowledge and discussion were reported despite prior HIV discrimination training and HIV-related practice experience. Study limitations include a small sample size and a modest response rate. Addressing stigma among dermatologists and improving HIV PrEP education is vital to enhancing the healthcare outcomes of people living with HIV.
    MeSH term(s) Humans ; HIV ; HIV Infections/prevention & control ; HIV Infections/drug therapy ; Pre-Exposure Prophylaxis ; Dermatology ; Anti-HIV Agents/therapeutic use ; Health Knowledge, Attitudes, Practice ; Surveys and Questionnaires
    Chemical Substances Anti-HIV Agents
    Language English
    Publishing date 2022-12-12
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 130131-7
    ISSN 1432-069X ; 0340-3696
    ISSN (online) 1432-069X
    ISSN 0340-3696
    DOI 10.1007/s00403-022-02500-6
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Synthesis of PMMA Microspheres with Tunable Diameters: Evaluation as a Template in the Synthesis of Tin Oxide Coatings.

    Mendoza-Castellanos, José L / Pantoja-Espinoza, Juan C / Rodríguez-Pacheco, Luis C / Paraguay-Delgado, Francisco

    Polymers

    2023  Volume 15, Issue 11

    Abstract: The synthesis of polymethyl methacrylate (PMMA) spheres with different sizes has been a challenge. PMMA has promise for future applications, e.g., as a template for preparing porous oxide coatings by thermal decomposition. Different amounts of SDS as a ... ...

    Abstract The synthesis of polymethyl methacrylate (PMMA) spheres with different sizes has been a challenge. PMMA has promise for future applications, e.g., as a template for preparing porous oxide coatings by thermal decomposition. Different amounts of SDS as a surfactant are used as an alternative to control PMMA microsphere size through the formation of micelles. The objectives of the study were twofold: firstly, to determine the mathematical relationship between SDS concentration and PMMA sphere diameter, and secondly, to assess the efficacy of PMMA spheres as templates for SnO
    Language English
    Publishing date 2023-05-23
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2527146-5
    ISSN 2073-4360 ; 2073-4360
    ISSN (online) 2073-4360
    ISSN 2073-4360
    DOI 10.3390/polym15112419
    Database MEDical Literature Analysis and Retrieval System OnLINE

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