LIVIVO - Search results -

Search results

Result 1 - 7 of total 7

Search options

Article: Doxycycline Prevents Preclinical Atherosclerosis, Pancreatic Islet Loss and Improves Insulin Secretion after Glycemic Stimulation: Preclinical Study in Individuals with a High-Fat Diet.

Rodriguez-Hernandez, Alejandrina / Delgado-Machuca, Marina / Guardado-Mendoza, Rodolfo / Mendoza-Hernandez, Martha A / Melnikov, Valery / Delgado-Enciso, Osiris G / Tiburcio-Jimenez, Daniel / Ceja-Espiritu, Gabriel / Hernandez-Fuentes, Gustavo A / Gamboa-Dominguez, Armando / Guzman-Esquivel, Jose / Martinez-Fierro, Margarita L / Rodriguez-Sanchez, Iram P / Delgado-Enciso, Ivan

Biomedicines

2023 Volume 11, Issue 3

Abstract: Doxycycline (Doxy) is an antibiotic, which has exhibited anti-inflammatory activity and glucose metabolism improvement. The present study was proposed to evaluate its effects on glucose metabolism and other associated processes, such as lipemia and ... ...

Abstract	Doxycycline (Doxy) is an antibiotic, which has exhibited anti-inflammatory activity and glucose metabolism improvement. The present study was proposed to evaluate its effects on glucose metabolism and other associated processes, such as lipemia and adipogenesis, as well as, to evaluate its effects on the liver, pancreas, and aorta in subjects fed with an occidental high-fat diet (HFD). The trial followed three groups of BALB/c mice for 6 months: (1) Standard diet (SD); (2) HFD-placebo (saline solution); and (3) HFD-Doxy (10 mg/kg/day). Intrahepatic fat accumulation (steatohepatosis) and the epididymal fat pad, as well as the hepatic inflammatory infiltrate and ALT serum levels were higher in both groups with the HFD (with/without doxycycline) in comparison with the SD group. The thickness of the aorta (preclinic atherosclerosis) was significantly elevated in the HFD group with respect to the HFD + Doxy and SD group, these two being similar groups to each other. The HFD-Doxy group had pancreatic morphological parameters very similar to those of the SD group; on the contrary, the HFD group reduced the number of pancreatic islets and the number of β cells per mm
Language	English
Publishing date	2023-02-27
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2720867-9
ISSN	2227-9059
ISSN	2227-9059
DOI	10.3390/biomedicines11030717
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

Article: Clinical Characteristics in the Acute Phase of COVID-19 That Predict Long COVID: Tachycardia, Myalgias, Severity, and Use of Antibiotics as Main Risk Factors, While Education and Blood Group B Are Protective.

Guzman-Esquivel, Jose / Mendoza-Hernandez, Martha A / Guzman-Solorzano, Hannah P / Sarmiento-Hernandez, Karla A / Rodriguez-Sanchez, Iram P / Martinez-Fierro, Margarita L / Paz-Michel, Brenda A / Murillo-Zamora, Efren / Rojas-Larios, Fabian / Lugo-Trampe, Angel / Plata-Florenzano, Jorge E / Delgado-Machuca, Marina / Delgado-Enciso, Ivan

Healthcare (Basel, Switzerland)

2023 Volume 11, Issue 2

Abstract: Background: Risk factors for developing long COVID are not clearly established. The present study was designed to determine if any sign, symptom, or treatment of the acute phase, or personal characteristics of the patient, is associated with the ... ...

Abstract	Background: Risk factors for developing long COVID are not clearly established. The present study was designed to determine if any sign, symptom, or treatment of the acute phase, or personal characteristics of the patient, is associated with the development of long COVID. Methods: A cohort study was carried out, randomly selecting symptomatic COVID-19 patients and not vaccinated. The severity of the acute illness was assessed through the number of compatible COVID-19 symptoms, hospitalizations, and the symptom severity score using a 10-point visual analog scale. Results: After multivariate analysis, a severity score ≥8 (RR 2.0, 95%CI 1.1-3.5, Conclusions: Further studies in diverse populations over time are needed to expand the knowledge that could lead us to prevent and/or treat long COVID.
Language	English
Publishing date	2023-01-09
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2721009-1
ISSN	2227-9032
ISSN	2227-9032
DOI	10.3390/healthcare11020197
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Article ; Online: Health and economic measures in response to the COVID-19 pandemic- Effect on street vendors.

Romero-Michel, Jessica C / Mokay-Ramírez, Karen A / Delgado-Machuca, Marina / Delgado-Enciso, Josuel / Aurelien-Cabezas, Nomely S / Tiburcio-Jimenez, Daniel / Meza-Robles, Carmen / Delgado-Enciso, Osiris G / Guzman Esquivel, José / Zaizar-Fregoso, Sergio A / Martinez Fierro, Margarita L / Rodriguez Sanchez, Iram P / Melnikov, Valery / Barajas-Saucedo, Carlos E / Lara-Esqueda, Agustin / Delgado-Enciso, Ivan

Journal of infection in developing countries

2021 Volume 15, Issue 2, Page(s) 198–203

Abstract: Introduction: COVID-19 pandemic affects human health and the global economy. Its evolution is unpredictable, making it hard for governments to provide response actions suited for all populations. Meanwhile, informal street workers carry on with their ... ...

Abstract	Introduction: COVID-19 pandemic affects human health and the global economy. Its evolution is unpredictable, making it hard for governments to provide response actions suited for all populations. Meanwhile, informal street workers carry on with their labor despite contingency measures to sustain their lives. The objective was to conduct a case-control study to become aware of how street vendors' economy is affected during the COVID-19 pandemic. Methodology: During phase 2 of the COVID-19 pandemic in a Mexican suburban city. We interviewed informal street vendors (cases) and formal employees (controls). Results: Before mobility restrictions were in place, population income came 1.5% from formal employment and 23.5% from informal employment (street vendors). Informal employees lived on less than the equivalent of 1.5 Big Macs per day (p <0.001). After the contingency measures, formal employment kept the same, while the informal employment ratio increased to 57.4% (p < 0.001). The street vendors were almost 100-times less likely to be concerned about the coronavirus outbreak (p < 0.001) and were 38-times less likely to stop working compared with the formal workers (p < 0.001). Conclusions: We have proven that street vendors are a sector of the population that is highly vulnerable to significant economic loss due to contingency measures. Informal workers cannot stop working despite the "Stay at Home" initiative because the government has not implemented strategies that guarantee their survival and their families. Therefore, street vendors continue to be a source of the virus's spread throughout cities.
MeSH term(s)	Adult ; COVID-19/economics ; COVID-19/psychology ; Case-Control Studies ; Cities ; Employment ; Female ; Health Knowledge, Attitudes, Practice ; Humans ; Income ; Male ; Mexico ; Middle Aged ; Poverty ; Small Business/economics ; Socioeconomic Factors
Language	English
Publishing date	2021-03-07
Publishing country	Italy
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2394024-4
ISSN	1972-2680 ; 2036-6590
ISSN (online)	1972-2680
ISSN	2036-6590
DOI	10.3855/jidc.13465
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Article: Systemic Administration of Neutral Electrolyzed Saline as a Novel Treatment for Rheumatoid Arthritis Reduces Mechanical and Inflammatory Damage to the Joints: Preclinical Evaluation in Mice.

Zaizar-Fregoso, Sergio A / Paz-Michel, Brenda A / Rodriguez-Hernandez, Alejandrina / Paz-Garcia, Juan / Aurelien-Cabezas, Nomely S / Tiburcio-Jimenez, Daniel / Melnikov, Valery / Murillo-Zamora, Efren / Delgado-Enciso, Osiris G / Cabrera-Licona, Ariana / Guzman-Esquivel, José / Barajas-Saucedo, Carlos E / Rodriguez-Sanchez, Iram P / Martinez-Fierro, Margarita L / Moy-López, Norma A / Lara-Esqueda, Agustin / Guzman-Muñiz, Jorge / Delgado-Machuca, Marina / Delgado-Enciso, Ivan

Evidence-based complementary and alternative medicine : eCAM

2022 Volume 2022, Page(s) 1717614

Abstract: Rheumatoid arthritis is globally present in about 1% of the population. This autoinflammatory disease modifies the connective tissue, causing pain and inflammation of the joints. Over time, it causes the loss of joint cartilage and bone mass, decreasing ... ...

Abstract	Rheumatoid arthritis is globally present in about 1% of the population. This autoinflammatory disease modifies the connective tissue, causing pain and inflammation of the joints. Over time, it causes the loss of joint cartilage and bone mass, decreasing the patient's quality of life. Treatment options now available either give symptomatic alleviation or alter the disease process. Nonetheless, adherence to chronic treatment is typically limited due to adverse effects. As a result, new therapy approaches, such as systemic administration of neutral electrolyzed saline to improve patients' quality of life, are being investigated. The study is a randomized prospective preclinical trial with a single-blind and a 4-arm parallel group using a collagen-induced mice model to generate rheumatoid arthritis. It was carried out on 36 male BALB/c mice, with the primary outcome measure being a scoring system for histopathologic assessment. When all groups are compared, there are significant differences. In addition, the animal model was validated by the healthy group. The animals treated with neutral electrolyzed saline had much less cartilage degradation, bone erosion, pannus development, and inflammation than the placebo-treated mice. Serum IL-6 levels were evaluated in parallel with disease severity expressed as synovitis grading of the affected joints. Spearman's rank correlation coefficient (Rs) = 0.399 (
Language	English
Publishing date	2022-06-02
Publishing country	United States
Document type	Journal Article
ZDB-ID	2171158-6
ISSN	1741-4288 ; 1741-427X
ISSN (online)	1741-4288
ISSN	1741-427X
DOI	10.1155/2022/1717614
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.A 5995: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
Jg. 1995 - 2021: Lesesall (2.OG)
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article ; Online: "I prefer to get coronavirus than to stop working": the street vendor's perspective.

Delgado-Enciso, Josuel / Delgado-Machuca, Marina / Mokay-Ramírez, Karen A / Barajas-Saucedo, Carlos E / Romero-Michel, Jessica C / Fuentes-Murguia, Mercedes / Aurelien-Cabezas, Nomely S / Tiburcio-Jimenez, Daniel / Toscano-Velazquez, Jose A / Meza-Robles, Carmen / Hernandez-Rangel, Alejandra E / Walle-Guillen, Mireya / Delgado-Enciso, Osiris G / Guzman Esquivel, Jose / Rojas-Larios, Fabian / Zaizar-Fregoso, Sergio A / Martinez-Fierro, Margarita L / Rodriguez Sanchez, Iram P / Melnikov, Valery /

Espinoza-Gomez, Francisco / Delgado-Enciso, Ivan

Journal of infection in developing countries

2021 Volume 15, Issue 11, Page(s) 1603–1606

Abstract: During phase 2 of the COVID-19 pandemic in a Mexican City, informal street vendors (cases) and formal employees (controls) were interviewed. A total of 82.6% of street vendors preferred to expose themselves to the coronavirus than to stop working, ... ...

Abstract	During phase 2 of the COVID-19 pandemic in a Mexican City, informal street vendors (cases) and formal employees (controls) were interviewed. A total of 82.6% of street vendors preferred to expose themselves to the coronavirus than to stop working, compared with 18.4% of formal employees (adjusted OR = 19.4, 95%CI: 4.6-81.7, p < 0.001). Street vendors had 7 times less fear of dying from coronavirus (adjusted OR = 0.14, 95% CI: 0.03-0.5, p = 0.005) and showed a 16-times greater lack of real concern for the increase in cases in their community than the formal employees (adjusted OR = 0.06, 95% CI: 0.01-0.3, p = 0.002). Street vendors were the group with the poorest adherence to household and work area containment measures that continued to be in contact with others. The corresponding authorities must plan specific strategies that allow street vendors to survive economically, while at the same time, protecting community health.
MeSH term(s)	Adult ; COVID-19/epidemiology ; COVID-19/transmission ; Female ; Health Behavior ; Humans ; Interviews as Topic ; Male ; Mexico/epidemiology ; Middle Aged ; Occupational Diseases/epidemiology ; Pandemics ; Poverty ; SARS-CoV-2 ; Workplace
Language	English
Publishing date	2021-11-30
Publishing country	Italy
Document type	Journal Article
ZDB-ID	2394024-4
ISSN	1972-2680 ; 2036-6590
ISSN (online)	1972-2680
ISSN	2036-6590
DOI	10.3855/jidc.13276
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Article: Patient-Reported Health Outcomes After Treatment of COVID-19 with Nebulized and/or Intravenous Neutral Electrolyzed Saline Combined with Usual Medical Care Versus Usual Medical care alone: A Randomized, Open-Label, Controlled Trial.

Delgado-Enciso, Ivan / Paz-Garcia, Juan / Barajas-Saucedo, Carlos E / Mokay-Ramírez, Karen A / Meza-Robles, Carmen / Lopez-Flores, Rodrigo / Delgado-Machuca, Marina / Murillo-Zamora, Efren / Toscano-Velazquez, Jose A / Delgado-Enciso, Josuel / Melnikov, Valery / Walle-Guillen, Mireya / Galvan-Salazar, Hector R / Delgado-Enciso, Osiris G / Cabrera-Licona, Ariana / Guzman-Esquivel, José / Montes-Galindo, Daniel A / Hemandez-Rangel, Alejandra E / Montes-Diaz, Patricia /

Rodriguez-Sanchez, Iram P / Martinez-Fierro, Margarita L / Garza-Veloz, Idalia / Tiburcio-Jimenez, Daniel / Zaizar-Fregoso, Sergio A / Ramirez-Flores, Mario / Gaytan-Sandoval, Gustavo / Martinez-Perez, Carlos R / Espinoza-Gómez, Francisco / Rojas-Larios, Fabián / Hirsch-Meillon, Michael J / Barrios-Navarro, Enrique / Oviedo-Rodriguez, Vladimir / Baltazar Rodriguez, Luz M / Paz-Michel, Brenda A

Research square

2020

Abstract: Background: ...

Abstract	Background:
Keywords	covid19
Language	English
Publishing date	2020-09-10
Publishing country	United States
Document type	Preprint
DOI	10.21203/rs.3.rs-68403/v1
Database	MEDical Literature Analysis and Retrieval System OnLINE

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Details ▾

Article ; Online: Safety and efficacy of a COVID-19 treatment with nebulized and/or intravenous neutral electrolyzed saline combined with usual medical care vs. usual medical care alone: A randomized, open-label, controlled trial.

Delgado-Enciso, Ivan / Paz-Garcia, Juan / Barajas-Saucedo, Carlos E / Mokay-Ramírez, Karen A / Meza-Robles, Carmen / Lopez-Flores, Rodrigo / Delgado-Machuca, Marina / Murillo-Zamora, Efren / Toscano-Velazquez, Jose A / Delgado-Enciso, Josuel / Melnikov, Valery / Walle-Guillen, Mireya / Galvan-Salazar, Hector R / Delgado-Enciso, Osiris G / Cabrera-Licona, Ariana / Danielewicz-Mata, Eduardo J / Mandujano-Diaz, Pablo J / Guzman-Esquivel, José / Montes-Galindo, Daniel A /

Perez-Martinez, Henry / Jimenez-Villegaz, Jesus M / Hernandez-Rangel, Alejandra E / Montes-Diaz, Patricia / Rodriguez-Sanchez, Iram P / Martinez-Fierro, Margarita L / Garza-Veloz, Idalia / Tiburcio-Jimenez, Daniel / Zaizar-Fregoso, Sergio A / Gonzalez-Alcaraz, Fidadelfo / Gutierrez-Gutierrez, Laydi / Diaz-Lopez, Luciano / Ramirez-Flores, Mario / Guzman-Solorzano, Hannah P / Gaytan-Sandoval, Gustavo / Martinez-Perez, Carlos R / Espinoza-Gómez, Francisco / Rojas-Larios, Fabián / Hirsch-Meillon, Michael J / Baltazar-Rodriguez, Luz M / Barrios-Navarro, Enrique / Oviedo-Rodriguez, Vladimir / Mendoza-Hernandez, Martha A / Prieto-Diaz-Chavez, Emilio / Paz-Michel, Brenda A

Experimental and therapeutic medicine

2021 Volume 22, Issue 3, Page(s) 915

Abstract: Coronavirus disease 2019 (COVID-19) is currently the major public health problem worldwide. Neutral electrolyzed saline solution that contains reactive chlorine and oxygen species may be an effective therapeutic. In the present study, the treatment ... ...

Abstract	Coronavirus disease 2019 (COVID-19) is currently the major public health problem worldwide. Neutral electrolyzed saline solution that contains reactive chlorine and oxygen species may be an effective therapeutic. In the present study, the treatment efficacy of intravenous and/or nebulized neutral electrolyzed saline combined with usual medical care vs. usual medical care alone was evaluated in ambulatory patients with COVID-19. A prospective, 2-arm, parallel-group, randomized, open-label, multi-center, phase I-II clinical trial including 214 patients was performed. The following two outcomes were evaluated during the 20-day follow-up: i) The number of patients with disease progression; and ii) the patient acceptable symptom state. Serial severe acute respiratory syndrome coronavirus 2 naso/oro-pharyngeal detection by reverse transcription-quantitative (RT-q) PCR was performed in certain patients of the experimental group. Biochemical and hematologic parameters, as well as adverse effects, were also evaluated in the experimental group. The experimental treatment decreased the risk of hospitalization by 89% [adjusted relative risk (RR)=0.11, 95% confidence interval (CI): 0.03-0.37, P<0.001] and the risk of death by 96% (adjusted RR=0.04, 95% CI: 0.01-0.42, P=0.007) and also resulted in an 18-fold higher probability of achieving an acceptable symptom state on day 5 (adjusted RR=18.14, 95% CI: 7.29-45.09, P<0.001), compared with usual medical care alone. Overall, neutral electrolyzed saline solution was better than usual medical care alone. Of the patients analyzed, >50% were negative for the virus as detected by RT-qPCR in naso/oro-pharyngeal samples on day 4, with only a small number of positive patients on day 6. Clinical improvement correlated with a decrease in C-reactive protein, aberrant monocytes and increased lymphocytes and platelets. Cortisol and testosterone levels were also evaluated and a decrease in cortisol levels and an increase in the testosterone-cortisol ratio were observed on days 2 and 4. The experimental treatment produced no serious adverse effects. In conclusion, neutral electrolyzed saline solution markedly reduced the symptomatology and risk of progression in ambulatory patients with COVID-19. The present clinical trial was registered in the Cuban public registry of clinical trials (RPCEC) database (May 5, 2020; no. TX-COVID19: RPCEC00000309).
Language	English
Publishing date	2021-06-29
Publishing country	Greece
Document type	Journal Article
ZDB-ID	2683844-8
ISSN	1792-1015 ; 1792-0981
ISSN (online)	1792-1015
ISSN	1792-0981
DOI	10.3892/etm.2021.10347
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

To top

Search results

Search options

Article: Doxycycline Prevents Preclinical Atherosclerosis, Pancreatic Islet Loss and Improves Insulin Secretion after Glycemic Stimulation: Preclinical Study in Individuals with a High-Fat Diet.

More links

Kategorien

Order via subito

Article: Clinical Characteristics in the Acute Phase of COVID-19 That Predict Long COVID: Tachycardia, Myalgias, Severity, and Use of Antibiotics as Main Risk Factors, While Education and Blood Group B Are Protective.

More links

Kategorien

Order via subito

Article ; Online: Health and economic measures in response to the COVID-19 pandemic- Effect on street vendors.

More links

Kategorien

Order via subito

Article: Systemic Administration of Neutral Electrolyzed Saline as a Novel Treatment for Rheumatoid Arthritis Reduces Mechanical and Inflammatory Damage to the Joints: Preclinical Evaluation in Mice.

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

Article ; Online: "I prefer to get coronavirus than to stop working": the street vendor's perspective.

More links

Kategorien

Order via subito

Article: Patient-Reported Health Outcomes After Treatment of COVID-19 with Nebulized and/or Intravenous Neutral Electrolyzed Saline Combined with Usual Medical Care Versus Usual Medical care alone: A Randomized, Open-Label, Controlled Trial.

More links

Kategorien

Inter-library loan at ZB MED

Article ; Online: Safety and efficacy of a COVID-19 treatment with nebulized and/or intravenous neutral electrolyzed saline combined with usual medical care vs. usual medical care alone: A randomized, open-label, controlled trial.

More links

Kategorien

Order via subito