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  1. Article ; Online: Burnout in science.

    Delgoffe, Greg M

    Immunology

    2023  Volume 169, Issue 1, Page(s) 1–2

    MeSH term(s) Humans ; Burnout, Professional/prevention & control ; Burnout, Psychological
    Language English
    Publishing date 2023-04-04
    Publishing country England
    Document type Editorial
    ZDB-ID 80124-0
    ISSN 1365-2567 ; 0019-2805 ; 0953-4954
    ISSN (online) 1365-2567
    ISSN 0019-2805 ; 0953-4954
    DOI 10.1111/imm.13639
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: What's in a name? Nomenclature in immunology.

    Delgoffe, Greg M

    Immunology

    2022  Volume 167, Issue 2, Page(s) 123

    Language English
    Publishing date 2022-09-20
    Publishing country England
    Document type Editorial
    ZDB-ID 80124-0
    ISSN 1365-2567 ; 0019-2805 ; 0953-4954
    ISSN (online) 1365-2567
    ISSN 0019-2805 ; 0953-4954
    DOI 10.1111/imm.13576
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: COVID-19 vaccination and treatment in vulnerable populations.

    Delgoffe, Greg M

    Immunology

    2022  Volume 165, Issue 2, Page(s) 141–142

    MeSH term(s) COVID-19/epidemiology ; COVID-19/immunology ; COVID-19/prevention & control ; COVID-19 Vaccines/administration & dosage ; COVID-19 Vaccines/immunology ; Humans ; SARS-CoV-2/immunology ; Vaccination
    Chemical Substances COVID-19 Vaccines
    Language English
    Publishing date 2022-01-08
    Publishing country England
    Document type Editorial
    ZDB-ID 80124-0
    ISSN 1365-2567 ; 0019-2805 ; 0953-4954
    ISSN (online) 1365-2567
    ISSN 0019-2805 ; 0953-4954
    DOI 10.1111/imm.13445
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Editorial: Highlighting early-career researchers-The future of Immunology.

    Delgoffe, Greg M

    Immunology

    2022  Volume 165, Issue 3, Page(s) 289

    Language English
    Publishing date 2022-02-11
    Publishing country England
    Document type Editorial
    ZDB-ID 80124-0
    ISSN 1365-2567 ; 0019-2805 ; 0953-4954
    ISSN (online) 1365-2567
    ISSN 0019-2805 ; 0953-4954
    DOI 10.1111/imm.13446
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  5. Article ; Online: Editorial: Streamlining the process of submissions to Immunology.

    Delgoffe, Greg M

    Immunology

    2022  Volume 166, Issue 3, Page(s) 267

    MeSH term(s) Editorial Policies
    Language English
    Publishing date 2022-06-21
    Publishing country England
    Document type Editorial
    ZDB-ID 80124-0
    ISSN 1365-2567 ; 0019-2805 ; 0953-4954
    ISSN (online) 1365-2567
    ISSN 0019-2805 ; 0953-4954
    DOI 10.1111/imm.13521
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  6. Article ; Online: Do we have a personnel crisis in immunology research?

    Delgoffe, Greg M

    Immunology

    2022  Volume 166, Issue 4, Page(s) 425–428

    Language English
    Publishing date 2022-05-12
    Publishing country England
    Document type Editorial
    ZDB-ID 80124-0
    ISSN 1365-2567 ; 0019-2805 ; 0953-4954
    ISSN (online) 1365-2567
    ISSN 0019-2805 ; 0953-4954
    DOI 10.1111/imm.13545
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  7. Article ; Online: Editorial: Diverse responses to SARS-CoV-2 in the human population.

    Delgoffe, Greg M

    Immunology

    2022  Volume 166, Issue 1, Page(s) 1

    Language English
    Publishing date 2022-04-17
    Publishing country England
    Document type Editorial
    ZDB-ID 80124-0
    ISSN 1365-2567 ; 0019-2805 ; 0953-4954
    ISSN (online) 1365-2567
    ISSN 0019-2805 ; 0953-4954
    DOI 10.1111/imm.13478
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  8. Article ; Online: Metabolic waypoints during T cell differentiation.

    Wilfahrt, Drew / Delgoffe, Greg M

    Nature immunology

    2024  Volume 25, Issue 2, Page(s) 206–217

    Abstract: This Review explores the interplay between T cell activation and cell metabolism and highlights how metabolites serve two pivotal functions in shaping the immune response. Traditionally, T cell activation has been characterized by T cell antigen receptor- ...

    Abstract This Review explores the interplay between T cell activation and cell metabolism and highlights how metabolites serve two pivotal functions in shaping the immune response. Traditionally, T cell activation has been characterized by T cell antigen receptor-major histocompatibility complex interaction (signal 1), co-stimulation (signal 2) and cytokine signaling (signal 3). However, recent research has unveiled the critical role of metabolites in this process. Firstly, metabolites act as signal propagators that aid in the transmission of core activation signals, such as specific lipid species that are crucial at the immune synapse. Secondly, metabolites also function as unique signals that influence immune differentiation pathways, such as amino acid-induced mTORC1 signaling. Metabolites also play a substantial role in epigenetic remodeling, by directly modifying histones, altering gene expression and influencing T cell behavior. This Review discusses how T cells integrate nutrient sensing with activating stimuli to shape their differentiation and sensitivity to metabolites. We underscore the integration of immunological and metabolic inputs in T cell function and suggest that metabolite availability is a fundamental determinant of adaptive immune responses.
    MeSH term(s) T-Lymphocytes ; Signal Transduction/physiology ; Cell Differentiation ; Lymphocyte Activation
    Language English
    Publishing date 2024-01-18
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 2016987-5
    ISSN 1529-2916 ; 1529-2908
    ISSN (online) 1529-2916
    ISSN 1529-2908
    DOI 10.1038/s41590-023-01733-5
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Meet the new Editor-in-Chief of Immunology: Greg M. Delgoffe, Ph.D.

    Delgoffe, Greg M

    Immunology

    2021  Volume 165, Issue 1, Page(s) 1–2

    Language English
    Publishing date 2021-12-13
    Publishing country England
    Document type Editorial
    ZDB-ID 80124-0
    ISSN 1365-2567 ; 0019-2805 ; 0953-4954
    ISSN (online) 1365-2567
    ISSN 0019-2805 ; 0953-4954
    DOI 10.1111/imm.13436
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Redox and detox: Malate shuttle metabolism keeps exhausted T cells fit.

    Kumar, Alok / Delgoffe, Greg M

    Cell metabolism

    2023  Volume 35, Issue 12, Page(s) 2101–2103

    Abstract: The malate shuttle is known to maintain the balance of ... ...

    Abstract The malate shuttle is known to maintain the balance of NAD
    MeSH term(s) Malates/metabolism ; Ammonia/metabolism ; T-Lymphocytes/metabolism ; Oxidation-Reduction ; Mitochondria/metabolism ; Cytosol/metabolism ; NAD/metabolism ; Aspartic Acid/metabolism ; Malate Dehydrogenase/metabolism
    Chemical Substances Malates ; Ammonia (7664-41-7) ; NAD (0U46U6E8UK) ; Aspartic Acid (30KYC7MIAI) ; Malate Dehydrogenase (EC 1.1.1.37)
    Language English
    Publishing date 2023-12-06
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2176834-1
    ISSN 1932-7420 ; 1550-4131
    ISSN (online) 1932-7420
    ISSN 1550-4131
    DOI 10.1016/j.cmet.2023.11.005
    Database MEDical Literature Analysis and Retrieval System OnLINE

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