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  1. Article: Concentration-response of an anthraquinone-based repellent for raccoons (Procyon lotor)

    Johnson, Shylo R. / Deliberto, Shelagh T. / Urchek, Kathleen / Gilbert, Amy T. / Werner, Scott J.

    Applied animal behaviour science. 2022 June, v. 251

    2022  

    Abstract: Wildlife repellents can be part of non-lethal management strategies to reduce the negative impacts of wildlife to property, agricultural production, and human health and safety. Raccoons (Procyon lotor) are associated with negative impacts in all three ... ...

    Abstract Wildlife repellents can be part of non-lethal management strategies to reduce the negative impacts of wildlife to property, agricultural production, and human health and safety. Raccoons (Procyon lotor) are associated with negative impacts in all three of these areas. Anthraquinone is a useful avian repellent and its utility as a mammalian repellent is still being explored. Our objective was to evaluate laboratory efficacy of an anthraquinone-based repellent for raccoons using different concentrations. We fed captive raccoons whole corn treated at 0.5%, 1%, 1.5% and 2% anthraquinone and examined their behavioral response related to feeding repellency including consumption and change in duration related to approach, interaction and extended interaction with the feed bowl. Feeding repellency was 26–37% for whole corn treated with 0.5–1.5% anthraquinone and 71% for whole corn treated with 2% anthraquinone. Interaction duration among the treatments varied (p = 0.005) with a longer interaction duration with the food bowl at 2% anthraquinone compared to 0.5% anthraquinone. However, the addition of anthraquinone did not significantly alter behaviors of approach, interaction, or extended interaction between pretreatment and treatment for the raccoons within treatments. The decreases in consumption that we observed warrant development of further research and field evaluation regarding anthraquinone as a deterrent with raccoons or to repel vertebrate competitors from raccoon specific baits.
    Keywords Procyon lotor ; animal behavior ; anthraquinones ; bird repellents ; corn ; human health and safety ; mammals ; wildlife
    Language English
    Dates of publication 2022-06
    Publishing place Elsevier B.V.
    Document type Article
    ZDB-ID 591645-8
    ISSN 0168-1591
    ISSN 0168-1591
    DOI 10.1016/j.applanim.2022.105628
    Database NAL-Catalogue (AGRICOLA)

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  2. Article: Neu5Gc binding loss of subtype H7 influenza A virus facilitates adaptation to gallinaceous poultry following transmission from waterbirds but restricts spillback.

    Guan, Minhui / Deliberto, Thomas J / Feng, Aijing / Zhang, Jieze / Li, Tao / Wang, Shuaishuai / Li, Lei / Killian, Mary Lea / Praena, Beatriz / Giri, Emily / Deliberto, Shelagh T / Hang, Jun / Olivier, Alicia / Torchetti, Mia Kim / Tao, Yizhi Jane / Parrish, Colin / Wan, Xiu-Feng

    bioRxiv : the preprint server for biology

    2024  

    Abstract: Migratory waterfowl, gulls, and shorebirds serve as natural reservoirs for influenza A viruses, with potential spillovers to domestic poultry and humans. The intricacies of interspecies adaptation among avian species, particularly from wild birds to ... ...

    Abstract Migratory waterfowl, gulls, and shorebirds serve as natural reservoirs for influenza A viruses, with potential spillovers to domestic poultry and humans. The intricacies of interspecies adaptation among avian species, particularly from wild birds to domestic poultry, are not fully elucidated. In this study, we investigated the molecular mechanisms underlying avian species barriers in H7 transmission, particularly the factors responsible for the disproportionate distribution of poultry infected with A/Anhui/1/2013 (AH/13)-lineage H7N9 viruses. We hypothesized that the differential expression of N-glycolylneuraminic acid (Neu5Gc) among avian species exerts selective pressure on H7 viruses, shaping their evolution and enabling them to replicate and transmit efficiently among gallinaceous poultry, particularly chickens. Our glycan microarray and biolayer interferometry experiments showed that AH/13-lineage H7N9 viruses exclusively bind to Neu5Ac, in contrast to wild waterbird H7 viruses that bind both Neu5Ac and Neu5Gc. Significantly, reverting the V179 amino acid in AH/13-lineage back to the I179, predominantly found in wild waterbirds, expanded the binding affinity of AH/13-lineage H7 viruses from exclusively Neu5Ac to both Neu5Ac and Neu5Gc. When cultivating H7 viruses in cell lines with varied Neu5Gc levels, we observed that Neu5Gc expression impairs the replication of Neu5Ac-specific H7 viruses and facilitates adaptive mutations. Conversely, Neu5Gc deficiency triggers adaptive changes in H7 viruses capable of binding to both Neu5Ac and Neu5Gc. Additionally, we assessed Neu5Gc expression in the respiratory and gastrointestinal tissues of seven avian species, including chickens, Canada geese, and various dabbling ducks. Neu5Gc was absent in chicken and Canada goose, but its expression varied in the duck species. In summary, our findings reveal the crucial role of Neu5Gc in shaping the host range and interspecies transmission of H7 viruses. This understanding of virus-host interactions is crucial for developing strategies to manage and prevent influenza virus outbreaks in diverse avian populations.
    Language English
    Publishing date 2024-01-03
    Publishing country United States
    Document type Preprint
    DOI 10.1101/2024.01.02.573990
    Database MEDical Literature Analysis and Retrieval System OnLINE

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