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  1. Article ; Online: Abnormal dot plots on current automated blood cell analyzer helped to yeast detection

    Delphine Gérard / Jean‐Francois Lesesve

    Clinical Case Reports, Vol 8, Iss 4, Pp 776-

    2020  Volume 777

    Abstract: Abstract Compromised data are usually flagged by instruments. This is the first report of yeast detection using the new launched Sysmex XN analyzer. ...

    Abstract Abstract Compromised data are usually flagged by instruments. This is the first report of yeast detection using the new launched Sysmex XN analyzer.
    Keywords blood cell counter ; Candidosis ; Sysmex XN9000 ; Medicine ; R ; Medicine (General) ; R5-920
    Language English
    Publishing date 2020-04-01T00:00:00Z
    Publisher Wiley
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  2. Article ; Online: Uncommon but valuable for diagnosis

    Jean‐François Lesesve / Delphine Gérard / Alice Burgevin

    Clinical Case Reports, Vol 9, Iss 3, Pp 1553-

    Green deposits on peritoneal fluid cytospins

    2021  Volume 1555

    Abstract: Abstract When ascites fluids are observed under the microscope, unshaped greenish deposits should not be considered as artifacts but should rather prompt to bile leakage assessment. ...

    Abstract Abstract When ascites fluids are observed under the microscope, unshaped greenish deposits should not be considered as artifacts but should rather prompt to bile leakage assessment.
    Keywords bile deposits ; gallbladder perforation ; morphology ; peritoneal fluid ; Medicine ; R ; Medicine (General) ; R5-920
    Language English
    Publishing date 2021-03-01T00:00:00Z
    Publisher Wiley
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    Full text online

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    Inter-library loan at ZB MED

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  3. Article: Tumor necrosis factor-alpha blockers in SAPHO syndrome.

    Ben Abdelghani, Kaouther / Dran, Delphine Gerard / Gottenberg, Jacques-Eric / Morel, Jacques / Sibilia, Jean / Combe, Bernard

    The Journal of rheumatology

    2010  Volume 37, Issue 8, Page(s) 1699–1704

    Abstract: Objective: To analyze the clinical efficacy of anti-tumor necrosis factor-alpha (TNF-alpha) therapy in treatment of synovitis, acne, pustulosis, hyperostosis, osteitis (SAPHO) syndrome, we describe cases of refractory SAPHO syndrome and review cases ... ...

    Abstract Objective: To analyze the clinical efficacy of anti-tumor necrosis factor-alpha (TNF-alpha) therapy in treatment of synovitis, acne, pustulosis, hyperostosis, osteitis (SAPHO) syndrome, we describe cases of refractory SAPHO syndrome and review cases treated with anti-TNF-alpha reported in the literature.
    Methods: We describe 6 cases of patients with SAPHO syndrome treated with anti-TNF-alpha between 2004 and 2008. Therapeutic response was evaluated according to improvement in pain score, amelioration of disease activity, and improvement in function. The efficacy of treatment was considered to be reduced need for analgesics and/or antiinflammatory therapy.
    Results: In our series, 4 patients received infliximab, 1 etanercept, and 1 adalimumab. These treatments brought clinical response in 4 patients (66.6%): response was sustained with infliximab in 1 case for 7 months; with adalimumab in another case for 22 months; and with etanercept in 2 cases for 1 and 42 months, respectively. In contrast, 2 other patients showed no response to infliximab. Improvement was initially temporary after infusions 1 and 2, then pain recurred at Week 14. Skin lesions were healed in 3 of 4 cases, but recurred or worsened in 2 cases, after infusion 2 of infliximab. Treatment was generally well tolerated. Paradoxical psoriasis was noted in 2 cases and urticaria in 1.
    Conclusion: Given our results and those from the literature, TNF-alpha blockers should be considered in the therapeutic strategy of refractory cases of SAPHO syndrome, despite their effect seeming less impressive than in other spondyloarthropathies.
    MeSH term(s) Acquired Hyperostosis Syndrome/drug therapy ; Acquired Hyperostosis Syndrome/physiopathology ; Adalimumab ; Adult ; Antibodies, Monoclonal/therapeutic use ; Antibodies, Monoclonal, Humanized ; Disability Evaluation ; Etanercept ; Female ; Health Status ; Humans ; Immunoglobulin G/therapeutic use ; Infliximab ; Middle Aged ; Receptors, Tumor Necrosis Factor/therapeutic use ; Severity of Illness Index ; Treatment Outcome ; Tumor Necrosis Factor-alpha/antagonists & inhibitors
    Chemical Substances Antibodies, Monoclonal ; Antibodies, Monoclonal, Humanized ; Immunoglobulin G ; Receptors, Tumor Necrosis Factor ; Tumor Necrosis Factor-alpha ; Infliximab (B72HH48FLU) ; Adalimumab (FYS6T7F842) ; Etanercept (OP401G7OJC)
    Language English
    Publishing date 2010-08-01
    Publishing country Canada
    Document type Case Reports ; Journal Article
    ZDB-ID 194928-7
    ISSN 1499-2752 ; 0315-162X
    ISSN (online) 1499-2752
    ISSN 0315-162X
    DOI 10.3899/jrheum.091086
    Database MEDical Literature Analysis and Retrieval System OnLINE

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