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  1. Article: Beauveria bassiana keratitis: Management of an atypical clinical presentation

    Ducange, Pietro / Verdina, Tommaso / Stiro, Fabio / Grottola, Antonella / Orlando, Gabriella / Delvecchio, Giancarlo / Mastropasqua, Rodolfo

    Medical mycology case reports. 2021 Sept., v. 33

    2021  

    Abstract: We report an atypical presentation of Beauveria bassiana keratitis which unusually presented in a 85-year-old patient with a corneal ulcer with an anterior segment inflammation and hypopyon. Despite negative culture and unspecific results from panfungal ... ...

    Abstract We report an atypical presentation of Beauveria bassiana keratitis which unusually presented in a 85-year-old patient with a corneal ulcer with an anterior segment inflammation and hypopyon. Despite negative culture and unspecific results from panfungal PCR-based sequencing, the patient was treated for a presumed fungal infection. Following clinical deterioration an emergency surgical intervention with apposition of a corneal patch was performed. Infection resolution was achieved following the introduction of systemic voriconazole to the topical one.
    Keywords Beauveria bassiana ; cornea ; fungi ; inflammation ; keratitis ; mycology ; patients ; polymerase chain reaction
    Language English
    Dates of publication 2021-09
    Size p. 1-4.
    Publishing place Elsevier B.V.
    Document type Article
    Note NAL-AP-2-clean
    ISSN 2211-7539
    DOI 10.1016/j.mmcr.2021.05.001
    Database NAL-Catalogue (AGRICOLA)

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  2. Article: Beauveria bassiana keratitis: Management of an atypical clinical presentation.

    Ducange, Pietro / Verdina, Tommaso / Stiro, Fabio / Grottola, Antonella / Orlando, Gabriella / Delvecchio, Giancarlo / Mastropasqua, Rodolfo

    Medical mycology case reports

    2021  Volume 33, Page(s) 1–4

    Abstract: We report an atypical presentation ... ...

    Abstract We report an atypical presentation of
    Language English
    Publishing date 2021-05-25
    Publishing country Netherlands
    Document type Case Reports
    ISSN 2211-7539
    ISSN 2211-7539
    DOI 10.1016/j.mmcr.2021.05.001
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Choroidal Changes in Blood Flow in Patients with Intermediate AMD after Oral Dietary Supplement Based on Astaxanthin, Bromelain, Vitamin D3, Folic Acid, Lutein, and Antioxidants.

    D'Aloisio, Rossella / Di Antonio, Luca / Toto, Lisa / Rispoli, Marco / Di Iorio, Angelo / Delvecchio, Giancarlo / Mastropasqua, Rodolfo

    Medicina (Kaunas, Lithuania)

    2022  Volume 58, Issue 8

    Abstract: Background and Objectives: The aim of this study was to investigate the impact of oral administration of the combination of astaxanthin (AXT), lutein, folic acid, vitamin D3, and bromelain with antioxidants on choroidal blood flow in patients with age- ... ...

    Abstract Background and Objectives: The aim of this study was to investigate the impact of oral administration of the combination of astaxanthin (AXT), lutein, folic acid, vitamin D3, and bromelain with antioxidants on choroidal blood flow in patients with age-related intermediate macular degeneration (AMD). Materials and Methods: Patients affected by intermediate AMD and treated with daily oral nutritional supplement with AXT, bromelain, vitamin D3, folic acid, lutein, and antioxidants for a period of at least 6 months were included in this retrospective study. A control group homogenous for age and sex was also included in the analysis. All participants underwent a complete ophthalmologic examination, spectral domain optical coherence tomography (SD-OCT), and optical coherence tomography angiography (OCTA) evaluation. Outcome measures were choroidal thickness (CHT) and choriocapillary vessel density (CCVD) after six months of AXT assumption. Results: CCVD values showed statistically significant difference between cases and controls at baseline (p < 0.001) and in the cases during follow-up (p < 0.001). The CHT measurements showed statistically significant difference between cases and controls (p = 0.002) and in the cases during follow-up (p < 0.001). Conclusions: The combined use of structural OCT and OCTA allows for a detailed analysis in vivo of perfusion parameters of the choriocapillaris and choroid and evaluation of changes of choroidal blood flow after oral nutritional supplements that affect blood flow velocity.
    MeSH term(s) Antioxidants/pharmacology ; Antioxidants/therapeutic use ; Bromelains ; Cholecalciferol ; Choroid ; Dietary Supplements ; Folic Acid/pharmacology ; Folic Acid/therapeutic use ; Humans ; Lutein/pharmacology ; Lutein/therapeutic use ; Macular Degeneration ; Retrospective Studies ; Tomography, Optical Coherence/methods ; Xanthophylls
    Chemical Substances Antioxidants ; Xanthophylls ; Cholecalciferol (1C6V77QF41) ; astaxanthine (8XPW32PR7I) ; Bromelains (9001-00-7) ; Folic Acid (935E97BOY8) ; Lutein (X72A60C9MT)
    Language English
    Publishing date 2022-08-12
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2188113-3
    ISSN 1648-9144 ; 1010-660X
    ISSN (online) 1648-9144
    ISSN 1010-660X
    DOI 10.3390/medicina58081092
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Long-term follow-up for bimanual microincision cataract surgery: comparison of results obtained by surgeons in training and experienced surgeons.

    Cavallini, Gian Maria / Verdina, Tommaso / Forlini, Matteo / Volante, Veronica / De Maria, Michele / Torlai, Giulio / Benatti, Caterina / Delvecchio, Giancarlo

    Clinical ophthalmology (Auckland, N.Z.)

    2016  Volume 10, Page(s) 979–987

    Abstract: Purpose: To determine the efficacy of bimanual microincision cataract surgery (B-MICS) performed by surgeons in training, evaluating clinical results, posterior capsule opacification (PCO) incidence, and clear corneal incision (CCI) architecture in a ... ...

    Abstract Purpose: To determine the efficacy of bimanual microincision cataract surgery (B-MICS) performed by surgeons in training, evaluating clinical results, posterior capsule opacification (PCO) incidence, and clear corneal incision (CCI) architecture in a long-term follow-up and comparing results with those obtained by experienced surgeons.
    Patients and methods: Eighty eyes of 62 patients operated on by three surgeons in training who used B-MICS technique for the first time were included in the study (Group A). Eighty eyes of 59 patients who underwent B-MICS by three experienced surgeons were included as a control group (Group B). Best corrected visual acuity, astigmatism, corneal pachymetry, and endothelial cell count were evaluated before surgery and at 1 month and 18 months after surgery. Anterior segment optical coherence tomography images were obtained to study the morphology of CCIs. PCO incidence was evaluated using EPCO2000 software.
    Results: Out of 160 surgeries included in the study, mean best-corrected visual acuity improvement at 18 months was 0.343±0.246 logMAR for Group A, and 0.388±0.175 logMAR for Group B, respectively. We found no statistically significant induced astigmatism nor corneal pachymetry changes in either group, while we noticed a statistically significant endothelial cell loss postoperatively in both groups (P<0.05). In Group A, mean PCO score was 0.163±0.196, while for Group B, it was 0.057±0.132 (P=0.0025). Mean length and inclination of the CCIs for Group A and Group B were, respectively, 1,358±175 µm and 1,437±256 µm and 141.8°±6.4° and 148.7°±5.1°. As regards corneal architecture in the 320 CCIs considered, we found posterior wound retractions and endothelial gaps, respectively, 9.8% and 11.6% for Group A and 7.8% and 10.8% for Group B.
    Conclusion: B-MICS performed by surgeons in training is an effective surgical technique even when assessed after a long-term follow-up. PCO incidence resulted in being higher for less experienced surgeons. Corneal incisions were shorter and less angled in surgeons in training in comparison with results obtained by expert surgeons.
    Language English
    Publishing date 2016-05-26
    Publishing country New Zealand
    Document type Journal Article
    ISSN 1177-5467
    ISSN 1177-5467
    DOI 10.2147/OPTH.S103540
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Results and complications of surgeons-in-training learning bimanual microincision cataract surgery.

    Cavallini, Gian Maria / Volante, Veronica / Verdina, Tommaso / Forlini, Matteo / Bigliardi, Maria Chiara / De Maria, Michele / Torlai, Giulio / Delvecchio, Giancarlo

    Journal of cataract and refractive surgery

    2015  Volume 41, Issue 1, Page(s) 105–115

    Abstract: Purpose: To evaluate visual outcomes and complications of bimanual microincision cataract surgery performed by surgeons in training.: Setting: Institute of Ophthalmology, University of Modena and Reggio Emilia, Modena, Italy.: Design: Prospective ... ...

    Abstract Purpose: To evaluate visual outcomes and complications of bimanual microincision cataract surgery performed by surgeons in training.
    Setting: Institute of Ophthalmology, University of Modena and Reggio Emilia, Modena, Italy.
    Design: Prospective case series.
    Methods: The corrected distance visual acuity (CDVA), astigmatism, corneal pachymetry, and endothelial cell count were evaluated before and 7 and 30 days after bimanual MICS performed by surgeons in training. Intraoperative and postoperative complications were also recorded.
    Results: Three surgeons in training performed bimanual MICS in 150 eyes of 131 patients. There were 18 intraoperative complications (12.0%) (10 iris traumas [6.6%]; 4 capsule ruptures without vitreous loss [2.7%]; 3 capsule ruptures with vitreous loss [2.0%]; 1 intraocular lens [IOL] implantation in the sulcus due to zonular laxity [0.7%]). There were 5 postoperative complications (3.3%) (2 iris prolapses [1.3%]; 1 IOL loop malposition [0.7%]; 1 narrowing of anterior chamber [0.7%]; 1 capsulorhexis phimosis [0.7%]). Thirty days postoperatively, the mean CDVA improvement was 0.53 ± 0.20 (Snellen decimal) (P < .05), the mean decrease in astigmatism was 0.09 ± 0.54 diopter (P = .29), and the mean increase in corneal pachymetry was 7.42 ± 22.01 μm (P = .12). There was statistically significant endothelial cell loss (mean 496.50 ± 469.66 cells/mm(2)) (P < .05).
    Conclusions: Bimanual MICS performed by surgeons in training was safe and effective. Visual outcomes and complication rates were similar to those reported for coaxial cataract surgery performed by surgeons in training.
    Financial disclosure: No author has a financial or proprietary interest in any material or method mentioned.
    MeSH term(s) Aged ; Aged, 80 and over ; Astigmatism/physiopathology ; Cataract Extraction/education ; Clinical Competence ; Corneal Endothelial Cell Loss/physiopathology ; Corneal Pachymetry ; Education, Medical, Graduate/statistics & numerical data ; Female ; Humans ; Incidence ; Internship and Residency ; Intraoperative Complications/epidemiology ; Learning Curve ; Lens Implantation, Intraocular ; Male ; Microsurgery/education ; Middle Aged ; Ophthalmology/education ; Postoperative Complications/epidemiology ; Prognosis ; Prospective Studies ; Visual Acuity/physiology
    Language English
    Publishing date 2015-01
    Publishing country United States
    Document type Journal Article
    ZDB-ID 632744-8
    ISSN 1873-4502 ; 0886-3350
    ISSN (online) 1873-4502
    ISSN 0886-3350
    DOI 10.1016/j.jcrs.2014.04.034
    Database MEDical Literature Analysis and Retrieval System OnLINE

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