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  1. Book: NCCN task force report: Update on the management of patients with gastrointestinal stromal tumors

    Demetri, George D.

    (Journal of the National Comprehensive Cancer Network ; 8, Suppl. 2)

    2010  

    Title variant Update on the management of patients with gastrointestinal stromal tumors
    Institution National Comprehensive Cancer Network
    Author's details George D. Demetri
    Series title Journal of the National Comprehensive Cancer Network ; 8, Suppl. 2
    Collection
    Language English
    Size S-44 S. : Ill.
    Publisher Cold Spring Publ
    Publishing place Cold Spring Harbor, NY
    Publishing country United States
    Document type Book
    HBZ-ID HT016371319
    Database Catalogue ZB MED Medicine, Health

    Kategorien

  2. Book ; Audio / Video ; Conference proceedings: Perspectives on multidisciplinary management of primary and metastatic GIST

    Demetri, George D.

    an expert forum ; 12 September 2008 ; ESMO Stockholm 2008 industry satellite symposium

    2008  

    Event/congress Satellite Symposium Entitled Perspectives on Multidisciplinary Management of Primary and Metastatic GIST (2008, Stockholm)
    Author's details Satellite Symposium Entitled Perspectives on Multidsciplinary Management of Primary and Metastatic GIST. Chairs/team leaders: George D. Demetri
    Language English
    Size 1 DVD, 12 cm
    Publisher Novartis
    Publishing place Basel
    Publishing country Switzerland
    Document type Book ; Audio / Video ; Conference proceedings
    HBZ-ID HT016650931
    Database Catalogue ZB MED Medicine, Health

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  3. Book ; Audio / Video ; Conference proceedings: Perspectives on multidisciplinary management of primary and metastatic GIST

    Demetri, George D.

    an expert forum ; 12 September 2008 ; ESMO Stockholm 2008 industry satellite symposium

    ([European journal of surgical oncology ; 34,11, Beil.])

    2008  

    Event/congress Satellite Symposium Entitled Perspectives on Multidisciplinary Management of Primary and Metastatic GIST (2008, Stockholm)
    Author's details Satellite Symposium Entitled Perspectives on Multidsciplinary Management of Primary and Metastatic GIST. Chairs/team leaders: George D. Demetri
    Series title [European journal of surgical oncology ; 34,11, Beil.]
    European journal of surgical oncology
    Collection European journal of surgical oncology
    Language English
    Size 1 CD-ROM, 12 cm
    Publisher Novartis
    Publishing place Basel
    Publishing country Switzerland
    Document type Book ; Audio / Video ; Conference proceedings
    HBZ-ID HT015833079
    Database Catalogue ZB MED Medicine, Health

    Kategorien

  4. Article ; Online: Real-World Evidence and Advanced Soft Tissue Sarcoma: An Unbreakable Bond (ESMO Sarcoma and GIST Symposium 2020 Industry Satellite Symposium, Milan, February 4, 2020).

    Demetri, George D

    Oncology

    2021  Volume 99 Suppl 1, Page(s) 1–2

    MeSH term(s) Congresses as Topic ; Evidence-Based Medicine ; Humans ; Sarcoma/therapy
    Language English
    Publishing date 2021-04-14
    Publishing country Switzerland
    Document type Editorial
    ZDB-ID 250101-6
    ISSN 1423-0232 ; 0030-2414
    ISSN (online) 1423-0232
    ISSN 0030-2414
    DOI 10.1159/000515265
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Book: NCCN task force report: Optimal management of patients with gastrointestinal stromal tumor (GIST)

    Demetri, George D.

    update of the NCCN clinical practice guidelines

    (Journal of the National Comprehensive Cancer Network ; 5, Suppl. 2)

    2007  

    Institution National Comprehensive Cancer Network
    Author's details George D. Demetri
    Series title Journal of the National Comprehensive Cancer Network ; 5, Suppl. 2
    Collection
    Language English
    Size S-32 S. : Ill.
    Publisher Jones and Bartlett
    Publishing place Boston u.a.
    Publishing country United States
    Document type Book
    HBZ-ID HT015519866
    Database Catalogue ZB MED Medicine, Health

    Kategorien

  6. Book: The evolution of a revolutionary class

    Blay, Jean-Yves / Demetri, George D.

    extending the benefits of tyrosine kinase inhibitors

    (Seminars in oncology ; 38,2, Suppl. 1)

    2011  

    Author's details Jean-Yves Blay and George D. Demetri, guest eds
    Series title Seminars in oncology ; 38,2, Suppl. 1
    Collection
    Language English
    Size S33 S. : graph. Darst.
    Publisher Saunders
    Publishing place Philadelphia, Pa
    Publishing country United States
    Document type Book
    HBZ-ID HT016785558
    Database Catalogue ZB MED Medicine, Health

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  7. Article ; Online: Evolution of the International Sarcoma Community: A Personal Perspective.

    Demetri, George D

    Oncology

    2018  Volume 95 Suppl 1, Page(s) 1–4

    MeSH term(s) Humans ; International Cooperation ; Sarcoma/therapy
    Language English
    Publishing date 2018-12-14
    Publishing country Switzerland
    Document type Editorial
    ZDB-ID 250101-6
    ISSN 1423-0232 ; 0030-2414
    ISSN (online) 1423-0232
    ISSN 0030-2414
    DOI 10.1159/000494859
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Contributions of Real-World Evidence and Real-World Data to Decision-Making in the Management of Soft Tissue Sarcomas.

    Demetri, George D / Stacchiotti, Silvia

    Oncology

    2021  Volume 99 Suppl 1, Page(s) 3–7

    Abstract: Real-world data are defined as data relating to any aspect of a patient's health status collected in the context of routine health surveillance and medical care delivery. Sources range from insurance billing claims through to electronic surveillance data ...

    Abstract Real-world data are defined as data relating to any aspect of a patient's health status collected in the context of routine health surveillance and medical care delivery. Sources range from insurance billing claims through to electronic surveillance data (e.g., activity trackers). Real-world data derive from large populations in diverse clinical settings and thus can be extrapolated more readily than clinical trial data to patients in different clinical settings or with a variety of comorbidities. Real-world data are used to generate real-world evidence, which might be regarded as a "meta-analysis" of accumulated real-world data. Increasingly, regulatory authorities are recognizing the value of real-world data and real-world evidence, especially for rare diseases where it may be practically unfeasible to conduct randomized controlled trials. However, the quality of real-world evidence depends on the quality of the data collected which, in turn, depends on a correct pathological diagnosis and the homogeneous behaviour of a reliably defined and consistent disease entity. As each of the more than 80 varieties of soft tissue sarcoma (STS) types represents a distinct disease entity, the situation is exceedingly complicated. Discordant diagnoses, which affect data quality, present a major challenge for use of real-world data. As real-world data are difficult to collect, collaboration across sarcoma reference institutions and sophisticated information technology solutions are required before the potential of real-world evidence to inform decision-making in the management of STS can be fully exploited.
    MeSH term(s) Clinical Trials as Topic ; Data Collection ; Decision Making ; Humans ; Information Technology ; Sarcoma/therapy
    Language English
    Publishing date 2021-04-14
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 250101-6
    ISSN 1423-0232 ; 0030-2414
    ISSN (online) 1423-0232
    ISSN 0030-2414
    DOI 10.1159/000515266
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Book: Monitoring blood plasma concentrations to improve outcomes in CML and GIST

    Egorin, Merrill J. / Larson, Richard A. / Demetri, George D.

    (Clinical advances in hematology & oncology ; 7,2, Suppl. 4 : Clinical roundtable monograph)

    2009  

    Author's details moderator Merrill J. Egorin. Discussants Richard A. Arson ; George D. Demetri
    Series title Clinical advances in hematology & oncology ; 7,2, Suppl. 4 : Clinical roundtable monograph
    Collection
    Language English
    Size 10 S. : Ill., graph. Darst.
    Publisher Millennium Med. Publ
    Publishing place New York, NY
    Publishing country United States
    Document type Book
    HBZ-ID HT016464911
    Database Catalogue ZB MED Medicine, Health

    Kategorien

  10. Article ; Online: Larotrectinib, a selective tropomyosin receptor kinase inhibitor for adult and pediatric tropomyosin receptor kinase fusion cancers.

    Farago, Anna F / Demetri, George D

    Future oncology (London, England)

    2020  Volume 16, Issue 9, Page(s) 417–425

    Abstract: Gene fusions ... ...

    Abstract Gene fusions involving
    MeSH term(s) Adult ; Biomarkers, Tumor/genetics ; Child ; Drug Resistance, Neoplasm/genetics ; Humans ; Membrane Glycoproteins/antagonists & inhibitors ; Membrane Glycoproteins/genetics ; Molecular Targeted Therapy ; Neoplasms/drug therapy ; Neoplasms/genetics ; Oncogene Proteins, Fusion/genetics ; Protein Kinase Inhibitors/therapeutic use ; Pyrazoles/therapeutic use ; Pyrimidines/therapeutic use ; Receptor, trkA/antagonists & inhibitors ; Receptor, trkA/genetics ; Receptor, trkB/antagonists & inhibitors ; Receptor, trkB/genetics ; Receptor, trkC/antagonists & inhibitors ; Receptor, trkC/genetics ; Treatment Outcome
    Chemical Substances Biomarkers, Tumor ; Membrane Glycoproteins ; NTRK1 protein, human ; NTRK3 protein, human ; Oncogene Proteins, Fusion ; Protein Kinase Inhibitors ; Pyrazoles ; Pyrimidines ; Receptor, trkA (EC 2.7.10.1) ; Receptor, trkB (EC 2.7.10.1) ; Receptor, trkC (EC 2.7.10.1) ; tropomyosin-related kinase-B, human (EC 2.7.10.1) ; larotrectinib (PF9462I9HX)
    Language English
    Publishing date 2020-03-04
    Publishing country England
    Document type Journal Article
    ZDB-ID 2274956-1
    ISSN 1744-8301 ; 1479-6694
    ISSN (online) 1744-8301
    ISSN 1479-6694
    DOI 10.2217/fon-2019-0647
    Database MEDical Literature Analysis and Retrieval System OnLINE

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