LIVIVO - Das Suchportal für Lebenswissenschaften

switch to English language
Erweiterte Suche

Ihre letzten Suchen

  1. AU="Demir, Necati"
  2. AU="Gottemoller, T.V."
  3. AU="Tyufekchieva, Violeta"
  4. AU="Prudhomme, Thomas"
  5. AU=Foecking Eileen M
  6. AU="A.Brillet, "
  7. AU="Rack-Helleis, J." AU="Rack-Helleis, J."
  8. AU="Mukhopadhyay, Ekta"
  9. AU="Jutta Niggemann"
  10. AU="Castilho, Grazielle Rodrigues"
  11. AU="Neza, Brian Nicholas"
  12. AU="van Oppen, Madeleine J H"
  13. AU="Cuevas, J."
  14. AU="Ekendahl, Daniela"
  15. AU="Cantoni, Valeria"
  16. AU="Barrett, Anne E"
  17. AU="van Steijn, Leonie"
  18. AU="Zeng, Zhenling"
  19. AU="Silva Helio B."
  20. AU="Bellicoso, Daniela"
  21. AU="Cruz Viggi, Carolina"

Suchergebnis

Treffer 1 - 10 von insgesamt 13

Suchoptionen

  1. Buch ; Dissertation / Habilitation: Induzierte pluripotente Stammzellen (iPS) und Linienreprogrammierung

    Demir, Necati

    Perspektiven für Knochenregeneration

    2011  

    Verfasserangabe vorgelegt von Necati Demir
    Sprache Deutsch
    Umfang 76 S.
    Erscheinungsland Deutschland
    Dokumenttyp Buch ; Dissertation / Habilitation
    Dissertation / Habilitation Köln, Univ., Diss., 2011
    HBZ-ID HT017062464
    Datenquelle Katalog ZB MED Medizin, Gesundheit

    Kategorien

  2. Buch ; Online ; Dissertation / Habilitation: Lentivirale Genexpressionsvektoren für die Gewinnung von Kardiomyozyten durch direkte Reprogrammierung somatischer Zellen

    Demir, Necati / Hescheler, Jürgen / Büning, Hildegard

    2012  

    Körperschaft Institut für Neurophysiologie
    Verfasserangabe vorgelegt von Necati Demir ; 1. Berichterstatter: Universitätsprofessor Dr. med. J. Hescheler, 2. Berichterstatterin: Frau Privatdozentin Dr. rer. nat. H. Büning ; aus dem Zentrum Physiologie und Pathophysiologie der Universität zu Köln, Institut für Neurophysiologie
    Thema/Rubrik (Code) 610
    Sprache Deutsch
    Umfang 82 S. : Ill., graph. Darst.
    Erscheinungsland Deutschland
    Dokumenttyp Buch ; Online ; Dissertation / Habilitation
    Dissertation / Habilitation Köln, Univ., Diss., 2012
    HBZ-ID HT017492219
    DOI 10.4126/38m-004900548
    Datenquelle Fachrepositorium Lebenswissenschaften

    Kategorien

  3. Buch ; Online ; Dissertation / Habilitation: Lentivirale Genexpressionsvektoren für die Gewinnung von Kardiomyozyten durch direkte Reprogrammierung somatischer Zellen

    Demir, Necati / Hescheler, Jürgen / Büning, Hildegard

    2012  

    Körperschaft Institut für Neurophysiologie
    Verfasserangabe vorgelegt von Necati Demir ; 1. Berichterstatter: Universitätsprofessor Dr. med. J. Hescheler, 2. Berichterstatterin: Frau Privatdozentin Dr. rer. nat. H. Büning ; aus dem Zentrum Physiologie und Pathophysiologie der Universität zu Köln, Institut für Neurophysiologie
    Thema/Rubrik (Code) 610
    Sprache Deutsch
    Umfang 82 S. : Ill., graph. Darst.
    Erscheinungsland Deutschland
    Dokumenttyp Buch ; Online ; Dissertation / Habilitation
    Dissertation / Habilitation Köln, Univ., Diss., 2012
    HBZ-ID HT017501967
    Datenquelle Katalog ZB MED Medizin, Gesundheit

    Kategorien

  4. Artikel ; Online: Time-related variations in viability of random pattern skin flaps: An experimental study in rats.

    Aydin, Osman Enver / Cicek, Kadir / Ceylan, Ender / Tuzcu, Ayca / Pehlevan, Anıl / Demir, Necati

    Chronobiology international

    2023  Band 40, Heft 10, Seite(n) 1454–1466

    Abstract: Chronobiological variations are in the fabric of life. The first ideas regarding the possible effects of circadian rhythm on surgical outcomes were published in the early 2000s. Some studies support and oppose this idea. The lack of experimental evidence ...

    Abstract Chronobiological variations are in the fabric of life. The first ideas regarding the possible effects of circadian rhythm on surgical outcomes were published in the early 2000s. Some studies support and oppose this idea. The lack of experimental evidence in a controlled setting has led to this study. This study aimed to explore the chronobiological implications of surgical outcomes. The rats were divided into four groups. A random pattern dorsal skin flaps were elevated in all groups at six h intervals. Flap necrosis rates and melatonin, oxidant, and antioxidant factors were studied. Flap survival was better in the 06:00 h group. The flap necrosis was higher in the 18:00 h group. Some of the biochemical parameters displayed circadian variations. As an independent variable, the time of surgical intervention changed the flap survival rates. It should be noted that the study was held in a nocturnal animal model thus the pattern of flap survival can be in reversed fashion in a clinical scenario. This study is the first experimental evidence for "Chronosurgery" in a controlled setting. Further studies in all aspects of surgical disciplines are required.
    Mesh-Begriff(e) Rats ; Animals ; Circadian Rhythm ; Surgical Flaps ; Antioxidants ; Melatonin/pharmacology ; Postoperative Complications ; Necrosis ; Skin
    Chemische Substanzen Antioxidants ; Melatonin (JL5DK93RCL)
    Sprache Englisch
    Erscheinungsdatum 2023-11-03
    Erscheinungsland England
    Dokumenttyp Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 998996-1
    ISSN 1525-6073 ; 0742-0528
    ISSN (online) 1525-6073
    ISSN 0742-0528
    DOI 10.1080/07420528.2023.2270706
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

    Zusatzmaterialien

    Kategorien

  5. Buch ; Online ; Dissertation / Habilitation: Lentivirale Genexpressionsvektoren für die Gewinnung von Kardiomyozyten durch direkte Reprogrammierung somatischer Zellen

    Demir, Necati [Verfasser]

    2012  

    Verfasserangabe Necati Demir
    Schlagwörter Medizin, Gesundheit ; Medicine, Health
    Thema/Rubrik (Code) sg610
    Sprache Deutsch
    Verlag Deutsche Zentralbibliothek für Medizin
    Erscheinungsort Köln
    Dokumenttyp Buch ; Online ; Dissertation / Habilitation
    Datenquelle Digitale Dissertationen im Internet

    Zusatzmaterialien

    Kategorien

  6. Artikel ; Online: Focal posterior pole viral retinitis.

    Hazirolan, Dicle / Sungur, Gulten / Demir, Necati / Kasim, Remzi / Duman, Sunay

    European journal of ophthalmology

    2010  Band 20, Heft 5, Seite(n) 925–930

    Abstract: Purpose: To describe the clinical features of an atypical form of viral retinitis in immunocompetent patients.: Methods: This was a retrospective noncomparative case series. The charts of 8 patients diagnosed with and treated for focal posterior ... ...

    Abstract Purpose: To describe the clinical features of an atypical form of viral retinitis in immunocompetent patients.
    Methods: This was a retrospective noncomparative case series. The charts of 8 patients diagnosed with and treated for focal posterior viral retinitis were reviewed. Clinical and demographic features were evaluated. All the patients had extensive laboratory tests, fundus fluorescein angiography, optical coherence tomography of macula, and polymerase chain reaction of vitreous.
    Results: All the patients were referred to our Uveitis Service from other hospitals, as their uveitis symptoms deteriorated in spite of treatment. The mean age of 4 male and 4 female patients was 32.1 years (range, 22-42 years). The mean follow-up period was 10 months (range, 6-18 months). All of the patients had unilateral disease. Polymerase chain reaction analysis of vitreous specimen was positive for herpes simplex virus-1 in 5 patients and varicella zoster virus in 3 patients. Retinitis resolved after systemic acyclovir treatment in all patients.
    Conclusions: Viral etiology must be borne in mind in the differential diagnosis of atypical retinitis. It can be a milder form of viral retinitis like focal viral retinitis, as mentioned in this study. The prognosis of this disease is better than the other forms of necrotizing retinopathies involving a larger area of retina.
    Mesh-Begriff(e) Acyclovir/therapeutic use ; Adult ; Antiviral Agents/therapeutic use ; DNA, Viral/analysis ; Eye Infections, Viral/diagnosis ; Eye Infections, Viral/drug therapy ; Eye Infections, Viral/virology ; Female ; Fluorescein Angiography ; Follow-Up Studies ; Herpes Simplex/diagnosis ; Herpes Simplex/drug therapy ; Herpes Simplex/virology ; Herpes Zoster Ophthalmicus/diagnosis ; Herpes Zoster Ophthalmicus/drug therapy ; Herpes Zoster Ophthalmicus/virology ; Herpesvirus 1, Human/genetics ; Herpesvirus 1, Human/isolation & purification ; Herpesvirus 3, Human/genetics ; Herpesvirus 3, Human/isolation & purification ; Humans ; Male ; Polymerase Chain Reaction ; Retinitis/diagnosis ; Retinitis/drug therapy ; Retinitis/virology ; Retrospective Studies ; Tomography, Optical Coherence ; Vitreous Body/virology ; Young Adult
    Chemische Substanzen Antiviral Agents ; DNA, Viral ; Acyclovir (X4HES1O11F)
    Sprache Englisch
    Erscheinungsdatum 2010-05-19
    Erscheinungsland United States
    Dokumenttyp Journal Article
    ZDB-ID 1089461-5
    ISSN 1724-6016 ; 1120-6721
    ISSN (online) 1724-6016
    ISSN 1120-6721
    DOI 10.1177/112067211002000518
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

    Zusatzmaterialien

    Kategorien

  7. Artikel ; Online: Eye patching as a treatment for amblyopia in children aged 10-16 years.

    Erdem, Elif / Çınar, Gül Yılmaz / Somer, Deniz / Demir, Necati / Burcu, Ayse / Örnek, Firdevs

    Japanese journal of ophthalmology

    2011  Band 55, Heft 4, Seite(n) 389–395

    Abstract: Purpose: To investigate the effects of full-time patching regimen on the treatment of amblyopia in children aged 10-16 years.: Methods: Forty-seven patients with a mean age of 12.09 ± 1.65 years were included in this study. All of the patients ... ...

    Abstract Purpose: To investigate the effects of full-time patching regimen on the treatment of amblyopia in children aged 10-16 years.
    Methods: Forty-seven patients with a mean age of 12.09 ± 1.65 years were included in this study. All of the patients received eye patching for the entire day, 6 days a week, during the first 3 months. The patients who achieved visual acuity of 0.00 logMAR at the third month were provided with additional patching treatment (4-6 h/day). On the other hand, the patients who showed no change in their visual acuity or an increase of less than 0.00 logMAR at the third month had 3 more months of eye patching for the entire day, 6 days a week.
    Results: Prior to treatment, the best mean visual acuity of the amblyopic eyes was 0.48 ± 0.25 (range 1.00-0.15) logMAR. After follow-up, the visual acuity of the amblyopic eyes was 0.20 ± 0.22 (range 1.00-0.00) logMAR. Thus, visual acuity in the amblyopic eyes improved by 0.2 log unit or more in 38 of 47 patients (81%).
    Conclusions: The present results show that patching in older children with amblyopia improves visual acuity with no serious complications. The use of patching in children to improve amblyopia seems promising.
    Mesh-Begriff(e) Adolescent ; Amblyopia/physiopathology ; Amblyopia/therapy ; Child ; Female ; Follow-Up Studies ; Humans ; Male ; Quality of Life ; Sensory Deprivation ; Time Factors ; Vision, Ocular ; Visual Acuity/physiology
    Sprache Englisch
    Erscheinungsdatum 2011-06-07
    Erscheinungsland Japan
    Dokumenttyp Journal Article
    ZDB-ID 82032-5
    ISSN 1613-2246 ; 0021-5155
    ISSN (online) 1613-2246
    ISSN 0021-5155
    DOI 10.1007/s10384-011-0029-z
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

    Zusatzmaterialien

    Kategorien

  8. Artikel: Duration of renal failure as risk factor for conjunctival squamous metaplasia.

    Demir, Necati / Altay, Mustafa / Ozer, Elif / Unlü, Nurten / Duranay, Murat / Ustün, Hüseyin / Duman, Sunay

    Acta cytologica

    2008  Band 52, Heft 3, Seite(n) 309–312

    Abstract: Objective: To assess ocular surface changes in patients with chronic renal failure (CRF), to compare the results with the duration of illness.: Study design: Impression cytology from 48 patients with CRF on regular hemodialysis and 16 age- and sex- ... ...

    Abstract Objective: To assess ocular surface changes in patients with chronic renal failure (CRF), to compare the results with the duration of illness.
    Study design: Impression cytology from 48 patients with CRF on regular hemodialysis and 16 age- and sex-matched control subjects were studied. Specimens were taken from the temporal bulbar conjunctiva using cellulose acetate filter paper.
    Results: Among the patients with CRF who were ill for 0-10 years, 25 patients (78.1%) disclosed grade 0-1, and 7 patients (21.9%) disclosed grade 2-3 cytologic changes, whereas in those with the duration of CRF > 10 years, 9 patients (56.2%) had grade 0-1 and 7 patients (43.8%) had grade 2-3 changes. Specimens from the control group revealed 93.8% grade 0-1 and 6.2% grade 2-3 changes (p < 0.05).
    Conclusion: The ocular surfaces of patients with CRF differ significantly from those of normal individuals, and the severity of conjunctival changes is related to the duration of CRF.
    Mesh-Begriff(e) Adult ; Cell Nucleus/pathology ; Conjunctiva/pathology ; Cytoplasm/pathology ; Epithelial Cells/pathology ; Female ; Goblet Cells/pathology ; Humans ; Kidney Failure, Chronic/complications ; Kidney Failure, Chronic/pathology ; Male ; Metaplasia ; Middle Aged ; Risk Factors ; Time Factors
    Sprache Englisch
    Erscheinungsdatum 2008-05
    Erscheinungsland Switzerland
    Dokumenttyp Comparative Study ; Journal Article
    ZDB-ID 80003-x
    ISSN 1938-2650 ; 0001-5547
    ISSN (online) 1938-2650
    ISSN 0001-5547
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

    Zusatzmaterialien

    Kategorien

  9. Artikel ; Online: Concise review: induced pluripotent stem cells and lineage reprogramming: prospects for bone regeneration.

    Illich, Damir J / Demir, Necati / Stojković, Miodrag / Scheer, Martin / Rothamel, Daniel / Neugebauer, Jörg / Hescheler, Jürgen / Zöller, Joachim E

    Stem cells (Dayton, Ohio)

    2011  Band 29, Heft 4, Seite(n) 555–563

    Abstract: Bone tissue for transplantation therapies is in high demand in clinics. Osteodegenerative diseases, in particular, osteoporosis and osteoarthritis, represent serious public health issues affecting a respectable proportion of the elderly population. ... ...

    Abstract Bone tissue for transplantation therapies is in high demand in clinics. Osteodegenerative diseases, in particular, osteoporosis and osteoarthritis, represent serious public health issues affecting a respectable proportion of the elderly population. Furthermore, congenital indispositions from the spectrum of craniofacial malformations such as cleft palates and systemic disorders including osteogenesis imperfecta are further increasing the need for bone tissue. Additionally, the reconstruction of fractured bone elements after accidents and the consumption of bone parts during surgical tumor excisions represent frequent clinical situations with deficient availability of healthy bone tissue for therapeutic transplantations. Epigenetic reprogramming represents a powerful technology for the generation of healthy patient-specific cells to replace or repair diseased or damaged tissue. The recent generation of induced pluripotent stem cells (iPSCs) is probably the most promising among these approaches dominating the literature of current stem cell research. It allows the generation of pluripotent stem cells from adult human skin cells from which potentially all cell types of the human body could be obtained. Another technique to produce clinically interesting cell types is direct lineage reprogramming (LR) with the additional advantage that it can be applied directly in vivo to reconstitute a damaged organ. Here, we want to present the two technologies of iPSCs and LR, to outline the current states of research, and to discuss possible strategies for their implementation in bone regeneration.
    Mesh-Begriff(e) Animals ; Bone Regeneration ; Bone Transplantation/methods ; Bone and Bones/physiology ; Cell Lineage ; Cellular Reprogramming ; Humans ; Induced Pluripotent Stem Cells/cytology ; Induced Pluripotent Stem Cells/metabolism ; Induced Pluripotent Stem Cells/transplantation
    Sprache Englisch
    Erscheinungsdatum 2011-04
    Erscheinungsland United States
    Dokumenttyp Journal Article ; Review
    ZDB-ID 1143556-2
    ISSN 1549-4918 ; 1066-5099
    ISSN (online) 1549-4918
    ISSN 1066-5099
    DOI 10.1002/stem.611
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

    Zusatzmaterialien

    Kategorien

  10. Artikel: Duration of Renal Failure as Risk Factor for Conjunctival Squamous Metaplasia

    Demir, Necati / Altay, Mustafa / Özer, Elif / Ünlü, Nurten / Duranay, Murat / Üstün, Hüseyin / Duman, Sunay

    Acta Cytologica

    2011  Band 52, Heft 3, Seite(n) 309–312

    Körperschaft From the Departments of Ophthalmology, Nephrology and Pathology, Ankara Training and Research Hospital, Ankara, Turkey
    Sprache Englisch
    Erscheinungsdatum 2011-02-16
    Verlag S. Karger AG
    Erscheinungsort Basel, Switzerland
    Dokumenttyp Artikel
    Anmerkung Nongynecologic Cytopathology
    ZDB-ID 80003-x
    ISSN 1938-2650 ; 0001-5547
    ISSN (online) 1938-2650
    ISSN 0001-5547
    DOI 10.1159/000325512
    Datenquelle Karger Verlag

    Zusatzmaterialien

    Kategorien

Zum Seitenanfang