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  1. Article ; Online: Primary cutaneous nocardiosis of the ankle caused by N. brasiliensis: a case report.

    Şahin, Suzan / Fidan, Ebru / Demir Tekol, Serap / Kaya, Bülent

    Infection

    2024  

    Abstract: Nocardia is a genus of aerobic, Gram-positive bacteria known for their filamentous and branching morphology. N. brasiliensis is the most common species causing cutaneous nocardiosis. We present a 67-year-old woman who developed abscesseson the back of ... ...

    Abstract Nocardia is a genus of aerobic, Gram-positive bacteria known for their filamentous and branching morphology. N. brasiliensis is the most common species causing cutaneous nocardiosis. We present a 67-year-old woman who developed abscesseson the back of her right ankle after walking barefoot on soil. Cultures from the cutaneous lesions grew N. brasiliensis. Antibiotic therapy with trimethoprim-sulfamethoxazole given for a month provided near-complete resolution of her lesions.
    Language English
    Publishing date 2024-04-26
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 185104-4
    ISSN 1439-0973 ; 0300-8126 ; 0173-2129
    ISSN (online) 1439-0973
    ISSN 0300-8126 ; 0173-2129
    DOI 10.1007/s15010-024-02273-2
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Salmonella gastroenteritis in children: six-year experience in İstanbul, Turkey.

    Karaaslan, Ayşe / Çetin, Ceren / Köle, Mehmet Tolga / Demir Tekol, Serap / Söbü, Elif / Akın, Yasemin

    Journal of infection in developing countries

    2022  Volume 16, Issue 11, Page(s) 1757–1761

    Abstract: Introduction: The aim of this study was to evaluate the demographic and clinical characteristics and treatment outcomes of children with Salmonella gastroenteritis.: Methodology: We retrospectively reviewed the medical records of pediatric patients ... ...

    Abstract Introduction: The aim of this study was to evaluate the demographic and clinical characteristics and treatment outcomes of children with Salmonella gastroenteritis.
    Methodology: We retrospectively reviewed the medical records of pediatric patients aged between 1 month and 18 years with the diagnosis of Salmonella gastroenteritis between May 2015 and December 2021.
    Results: A total of 172 children diagnosed with Salmonella gastroenteritis, including 113 outpatients and 59 hospitalized children, were included in this study. There were 95 (55.2%) males and 77 (44.8%) females with a median age of 59.5 months (interquartile range [IQR]: 33.5-96 months, min-max: 1-205 months). The most common clinical symptoms were diarrhea (n = 166, 96.5%), fever (n = 113, 65.7%) and abdominal pain (n = 73, 42.4%). Bloody diarrhea was seen in 19.2% of patients. Fifty (29.1%) of the Salmonella species could not be typed. Serogroup D (n = 106, 61.6%) was the predominant serogroup isolated from stool cultures, followed by serogroup B (n = 16, 9.3%). 62.2% of the isolates were susceptible to ampicillin, 97.7% to ciprofloxacin, 98.8% to trimethoprim-sulfamethoxazole, and 98.8% to ceftriaxone. Fever, vomiting, and underlying disease occurred more frequently in hospitalized patients than in outpatients (p: 0.005, p: 0.000, p: 0.000, respectively). C-reactive protein value was found to be higher in hospitalized patients (p: 0.000).
    Conclusions: Salmonella should be considered as a causative agent in pediatric patients with abdominal pain, fever, and bloody-mucous diarrhea, and patients with severe clinical conditions should be hospitalized and antibiotic therapy initiated if indicated.
    MeSH term(s) Female ; Male ; Humans ; Child ; Infant ; Child, Preschool ; Turkey/epidemiology ; Retrospective Studies ; Salmonella Food Poisoning ; Diarrhea/epidemiology ; Fever ; Abdominal Pain/epidemiology ; Gastroenteritis/drug therapy ; Gastroenteritis/epidemiology
    Language English
    Publishing date 2022-11-29
    Publishing country Italy
    Document type Journal Article
    ZDB-ID 2394024-4
    ISSN 1972-2680 ; 2036-6590
    ISSN (online) 1972-2680
    ISSN 2036-6590
    DOI 10.3855/jidc.17042
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Coinfection in SARS-CoV-2 Infected Children Patients.

    Karaaslan, Ayşe / Çetin, Ceren / Akın, Yasemin / Demir Tekol, Serap / Söbü, Elif / Demirhan, Recep

    Journal of infection in developing countries

    2021  Volume 15, Issue 6, Page(s) 761–765

    Abstract: Introduction: The aim of this study is to determine the coinfections with other respiratory pathogens in SARS-CoV-2 infected children patients in a pediatric unit in Istanbul.: Methodology: This retrospective descriptive study was conducted in a 1000- ...

    Abstract Introduction: The aim of this study is to determine the coinfections with other respiratory pathogens in SARS-CoV-2 infected children patients in a pediatric unit in Istanbul.
    Methodology: This retrospective descriptive study was conducted in a 1000-bedded tertiary education and research hospital in Istanbul. All children hospitalized with the diagnosis of SARS-CoV-2 infection had been investigated for respiratory agents in nasopharyngeal secretions. Laboratory confirmation of SARS-CoV-2 and the other respiratory pathogens were performed using reverse transcriptase-polymerase chain reaction (RT-PCR).
    Results: A total of 209 hospitalized children with suspected SARS-CoV-2 infection between March 2020-May 2020 were enrolled in this study. Among 209 children, 93 (44.5%) were RT-PCR positive for SARS-CoV-2 infection, and 116 (55.5%) were RT-PCR negative. The most common clinical symptoms in all children with SARS-CoV-2 infection were fever (68.8%) and cough (57.0%). The other clinical symptoms in decreasing rates were headache (10.8%), myalgia (5.4%), sore throat (3.2%), shortness of breath (3.2%), diarrhea (2.2%) and abdominal pain in one child. In 7 (7.5%) patients with SARS-CoV-2 infection, coinfection was detected. Two were with rhinovirus/enterovirus, two were with Coronavirus NL63, one was with adenovirus, and one was with Mycoplasma pneumoniae. In one patient, two additional respiratory agents (rhinovirus/enterovirus and adenovirus) were detected. There was a significantly longer hospital stay in patients with coinfection (p = 0.028).
    Conclusions: Although the coinfection rate was low in SARS-CoV-2 infected patients in our study, we found coinfection as a risk factor for length of hospital stay in the coinfected patient group.
    MeSH term(s) Adenoviridae/genetics ; Adolescent ; COVID-19/diagnosis ; COVID-19/microbiology ; COVID-19/virology ; Child ; Child, Preschool ; Coinfection/diagnosis ; Coinfection/epidemiology ; Coinfection/microbiology ; Coinfection/virology ; Hospitalization/statistics & numerical data ; Humans ; Length of Stay/statistics & numerical data ; Mycoplasma pneumoniae/genetics ; Mycoplasma pneumoniae/isolation & purification ; Nasopharynx/microbiology ; Nasopharynx/virology ; Qualitative Research ; Respiratory System/microbiology ; Respiratory System/virology ; Retrospective Studies ; SARS-CoV-2/genetics ; Tertiary Care Centers/statistics & numerical data ; Turkey/epidemiology ; Viruses/classification ; Viruses/genetics ; Viruses/isolation & purification
    Language English
    Publishing date 2021-06-30
    Publishing country Italy
    Document type Journal Article
    ZDB-ID 2394024-4
    ISSN 1972-2680 ; 2036-6590
    ISSN (online) 1972-2680
    ISSN 2036-6590
    DOI 10.3855/jidc.14314
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Infections in Pediatric Patients With Burn Injury: 6 Years of Experience.

    Karaaslan, Ayşe / Çetin, Ceren / Köle, Mehmet Tolga / Dereli, Murat / Demir Tekol, Serap / Filinte, Gaye / Akin, Yasemin

    The Pediatric infectious disease journal

    2022  Volume 42, Issue 1, Page(s) 8–12

    Abstract: Background: This study aimed to determine the frequency of bloodstream and wound infections and their possible risk factors in hospitalized children with burn injury.: Methods: We performed this retrospective descriptive study from 2015 to 2021. The ... ...

    Abstract Background: This study aimed to determine the frequency of bloodstream and wound infections and their possible risk factors in hospitalized children with burn injury.
    Methods: We performed this retrospective descriptive study from 2015 to 2021. The study subjects consisted of all the pediatric patients hospitalized in the burn unit, from whom microorganisms were isolated either from blood or wound culture samples.
    Results: We detected a total of 142 microorganisms from 97 blood culture samples and 45 wound culture samples. Among the 115 patients, 44 (38.3%) were females and 71 (61.7%) were males, with a median age of 21 months (interquartile range: 14-39 months). Gram-positive bacteria were the most common causative agents of bloodstream infections in patients with burns (54.6%), followed by Gram-negative bacteria (32.9%) and fungi (12.3%). Gram-negative bacteria were the most common causative agent of wound infections (86.7%). Prolonged hospitalization positively correlated with the extent of the burn surface area (P: 0.031), degree of burn (P: 0.001), use of central venous catheter (P: 0.028), and intensive care unit stay (P: 0.044). Independent risk factors for Gram-negative bacteremia and Gram-negative wound infections were the extent of the burn surface area (P: 0.018), degree of burn (P: 0.024) and intensive care unit stay (P: 0.023). The independent risk factor for fungemia was prolonged hospitalization (P: 0.026).
    Conclusions: To reduce infections, minimizing invasive procedures using a multidisciplinary approach would be beneficial, especially in patients who have a large burn surface area and are expected to have a long hospital stay.
    MeSH term(s) Child ; Child, Preschool ; Humans ; Infant ; Retrospective Studies ; Burns/complications ; Wound Infection
    Language English
    Publishing date 2022-10-12
    Publishing country United States
    Document type Journal Article
    ZDB-ID 392481-6
    ISSN 1532-0987 ; 0891-3668
    ISSN (online) 1532-0987
    ISSN 0891-3668
    DOI 10.1097/INF.0000000000003741
    Database MEDical Literature Analysis and Retrieval System OnLINE

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