Article ; Online: Viral load scale-up in south Sudan: Strategic implementation of tools to monitor HIV treatment success among people living with HIV.
International journal of STD & AIDS
2022 Volume 33, Issue 8, Page(s) 784–791
Abstract: Introduction: As access to antiretroviral therapy (ART) for people with HIV (PWH) in the Republic of South Sudan (RSS) increases, viral load (VL) suppression is critical to protect global HIV response investments. We describe VL scale-up between 2017- ... ...
| Abstract | Introduction: As access to antiretroviral therapy (ART) for people with HIV (PWH) in the Republic of South Sudan (RSS) increases, viral load (VL) suppression is critical to protect global HIV response investments. We describe VL scale-up between 2017-2020 in the RSS President's Emergency Plan for AIDS Relief (PEPFAR)-supported program. Methods: President's Emergency Plan for AIDS Relief (PEPFAR) South Sudan developed a VL scale-up plan and tools spanning the VL cascade: pre-test, test and post-test and included assessment of clinical facility and laboratory readiness; clinical and laboratory forms and standard operating procedures for test ordering, specimen collection, processing, results return and utilization; procedures to map clients, monitor turn-around-times (TAT), and an electronic system to monitor VL performance. Results: Between 2017 to 2020, VL monitoring was established in 58 facilities, with 59,600 VL samples processed, and improvements in TAT (150-28 days) and rejection rates (1.9%-0.8%). VL documentation improved for dates of ART initiation, VL test request and dispatch, and HIV regimen. Total average time from high VL to repeat VL decreased from 15.9 months to 6.4 months in 2017 and 2019, respectively. Conclusions: A concerted approach to VL scale-up has been fundamental as South Sudan strives towards UNAIDS 95-95-95 targets for PWH on ART. |
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| MeSH term(s) | Acquired Immunodeficiency Syndrome/drug therapy ; Anti-HIV Agents/therapeutic use ; Anti-Retroviral Agents/therapeutic use ; HIV Infections/diagnosis ; HIV Infections/drug therapy ; Humans ; South Sudan ; Viral Load |
| Chemical Substances | Anti-HIV Agents ; Anti-Retroviral Agents |
| Language | English |
| Publishing date | 2022-05-26 |
| Publishing country | England |
| Document type | Journal Article ; Research Support, U.S. Gov't, Non-P.H.S. |
| ZDB-ID | 1018089-8 |
| ISSN | 1758-1052 ; 0956-4624 |
| ISSN (online) | 1758-1052 |
| ISSN | 0956-4624 |
| DOI | 10.1177/09564624221103045 |
| Database | MEDical Literature Analysis and Retrieval System OnLINE |
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